Publications by Professor Catharien Hilkens - ePrints

Browsing publications by Professor Catharien Hilkens.

Newcastle Authors	Title	Year
Dan Salthouse Peter Goulding Sophie Reay Emma Jackson Professor Katarina Novakovic et al.	Amine-reactive crosslinking enhances type 0 collagen hydrogel properties for regenerative medicine	2024
Dr Luke Milross Bethany Hunter Dr David McDonald George Merces Dr Amanda Thomson et al.	Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19	2024
Bethany Hunter Dr Ioana Nicorescu Emma Foster Dr David McDonald Dr Gill Hulme et al.	OPTIMAL: An OPTimized Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration	2024
Professor Catharien Hilkens Julie Diboll Dr Fiona Cooke Dr Amy Anderson	In vitro generation of human tolerogenic monocyte-derived dendritic cells	2023
Professor Catharien Hilkens	Challenges in tolerogenic dendritic cell therapy for autoimmune diseases: the route of administration	2023
Dr Sophie Reay Emma Jackson Dan Salthouse Dr Ana Ferreira-Duarte Professor Catharien Hilkens et al.	Effective Endotoxin Removal from Chitosan That Preserves Chemical Structure and Improves Compatibility with Immune Cells	2023
Sophie Reay Emma Jackson Dan Salthouse Dr Ana Ferreira-Duarte Professor Catharien Hilkens et al.	Effective Endotoxin Removal from Chitosan that Preserves Chemical Structure and Improves Compatibility with Immune Cells	2023
Dan Salthouse Professor Katarina Novakovic Professor Catharien Hilkens Dr Ana Ferreira-Duarte	Interplay between biomaterials and the immune system: Challenges and opportunities in regenerative medicine	2023
Ayesha Sahar Dr Ioana Nicorescu Professor Catharien Hilkens Dr Phillip Lord	Tolerogenic dendritic cell reporting: Has a minimum information model made a difference?	2023
Dr Sophie Reay Emma Jackson Dr Ana Ferreira-Duarte Professor Catharien Hilkens Professor Katarina Novakovic et al.	In vitro evaluation of the biodegradability of chitosan–genipin hydrogels	2022
Dr Fiona Cooke Dr Mary Neal Dr Matthew Wood Dr Amy Anderson Julie Diboll et al.	Fluorine labelling of therapeutic human tolerogenic dendritic cells for 19F-magnetic resonance imaging	2022
Professor John Isaacs Sarah Brockbank Dr Ayako Pedersen Professor Catharien Hilkens Dr Amy Anderson et al.	RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients	2022
Professor Katarina Novakovic Dr Sophie Reay Dr Ana Ferreira-Duarte Professor Catharien Hilkens	Towards biocompatible pulsatile materials	2022
Dr Fiona Rayner Dr Amy Anderson Dr Ken Baker Professor Christopher Buckley Dr Bernard Dyke et al.	BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study	2021
Leonie Schittenhelm Dr Arthur Pratt Professor Catharien Hilkens	Dendritic cell integrin expression patterns regulate inflammation in the rheumatoid arthritis joint	2021
Professor Catharien Hilkens Professor Paul Garside	Preclinical models of arthritis for studying immunotherapy and immune tolerance	2021
Dr Amanda Thomson Professor Catharien Hilkens	Synovial Macrophages in Osteoarthritis: The Key to Understanding Pathogenesis?	2021
Dr Matthew Wood Adam Leckenby Dr Gary Reynolds Dr Rachel Spiering Dr Arthur Pratt et al.	Macrophage proliferation distinguishes 2 subgroups of knee osteoarthritis patients	2019
Dr Rachel Spiering Professor Catharien Hilkens	Matured tolerogenic dendritic cells effectively inhibit autoantigen specific CD4+ T cells in a murine arthritis model	2019
Dr Rachel Spiering Matthew Wood Anshor Fath Oliver Eltherington Dr Amy Anderson et al.	Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis	2019
Professor Catharien Hilkens	Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective	2019
Dr Rachel Spiering Professor John Isaacs Professor Catharien Hilkens Dr Phillip Lord	Minimum information about T regulatory cells: A step toward reproducibility and standardization	2018
Dr Faye Cooles Dr Amy Anderson Andrew Skelton Dr Arthur Pratt Professor Iain McInnes et al.	Phenotypic and transcriptomic analysis of peripheral blood plasmacytoid and conventional dendritic cells in early drug naïve rheumatoid arthritis	2018
Dr Rachel Spiering Professor John Isaacs Professor Catharien Hilkens	Targeting of tolerogenic dendritic cells towards heat-shock proteins: A novel therapeutic strategy for autoimmune diseases?	2018
Dr Aisha Blfgeh Dr Jennifer Warrender Professor Catharien Hilkens Dr Phillip Lord	A document-centric approach for developing the tolAPC ontology	2017
Dr Gillian Bell Dr Amy Anderson Julie Diboll Oliver Eltherington Dr Rachel Harry et al.	Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis	2017
Professor Catharien Hilkens	Cell-based tolerogenic therapy, experience from animal models of multiple sclerosis, type 1 diabetes and rheumatoid arthritis	2017
Dr Faye Cooles Dr Amy Anderson Dr Dennis Lendrem Julie Norris Dr Arthur Pratt et al.	The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy	2017
Dr Amy Anderson Dr David Swan Oliver Eltherington Dr Arthur Pratt Dr Gary Reynolds et al.	Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4⁺ T-cells partly via TGF-β1	2017
Joseph Cowell Matthew Buck Rebecca Clarke Professor Waldemar Vollmer Dr Daniela Vollmer et al.	Traceless-Cleavage of Protein-Biotin Conjugates Under Biologically-Compatible Conditions	2017
Dr Tom Clifford Matt Wood Philip Stocks Professor Emma Stevenson Professor Catharien Hilkens et al.	T-regulatory cells exhibit a biphasic response to prolonged endurance exercise in humans	2017
Leonie Schittenhelm Professor Catharien Hilkens	β2 Integrins As Regulators of Dendritic Cell, Monocyte, and Macrophage Function	2017
Dr Aisha Blfgeh Dr Jennifer Warrender Professor Catharien Hilkens Dr Phillip Lord	A document-centric approach for developing the tolAPC Ontology	2016
Dr Katherine Crossland Dr Mario Abinun Professor Timothy Cheetham Professor Simon Pearce Professor Catharien Hilkens et al.	AIRE is not essential for the induction of human tolerogenic dendritic cells	2016
Professor Ioakim Spyridopoulos Dr Carmen Martin-Ruiz Professor Catharien Hilkens Mohammad Yadegarfar Professor John Isaacs et al.	CMV-seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians - results from the Newcastle 85+ study	2016
Professor Catharien Hilkens	Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4⁺ T Cells	2016
Dr Phillip Lord Dr Rachel Spiering Dr Amy Anderson Julie Diboll Emeritus Professor Lindsay Marshall et al.	Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies	2016
Dr Phillip Lord Professor Catharien Hilkens	Ontology in Immunology	2016
Chris Tibbitt Dr Jane Falconer Dr Jeroen Stoop Emeritus Professor John Robinson Professor Catharien Hilkens et al.	Reduced TCR-dependent activation through citrullination of a T-cell epitope enhances Th17 development by disruption of the STAT3/5 balance	2016
Dr Gary Reynolds Dr Arthur Pratt Dr David Coady Dr Graham Raftery Dr Alice Lorenzi et al.	Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis	2016
Professor Catharien Hilkens	Treatment with Dexamethasone and Monophosphoryl Lipid A Removes Disease-Associated Transcriptional Signatures in Monocyte-Derived Dendritic Cells from Rheumatoid Arthritis Patients and Confers Tolerogenic Features	2016
Dr Gary Reynolds Dr Paul Milne Dr Venetia Bigley Professor Matthew Collin Professor John Isaacs et al.	Use of the dendritic cell marker, B and T lymphocyte attenuator, to identify functionally distinct subsets of human CD1c+ dendritic cells	2016
Professor Catharien Hilkens Dr Phillip Lord	Clinical Use of Tolerogenic Dendritic Cells-Harmonization Approach in European Collaborative Effort	2015
Professor Catharien Hilkens	Hurdles in therapy with regulatory T cells	2015
Dr Faye Cooles Dr Amy Anderson Professor Catharien Hilkens Professor John Isaacs	The Interferon Gene Signature in Early Rheumatoid Arthritis Demonstrates No Significant Association with Disease Activity	2015
Harriet Purvis Dr Amy Anderson Professor David Young Professor John Isaacs Professor Catharien Hilkens et al.	A Negative Feedback Loop Mediated by STAT3 Limits Human Th17 Responses	2014
Dr Gillian Bell Dr Amy Anderson Julie Diboll Dr Rachel Harry Emerita Professor Elaine McColl et al.	Autologous Tolerogenic Dendritic Cells for Rheumatoid and Inflammatory Arthritis.	2014
Dr Gillian Bell Dr Amy Anderson Dr Rachel Harry Julie Diboll Emerita Professor Elaine McColl et al.	Autologous tolerogenic dendritic cells in rheumatoid and inflammatory arthritis	2014
Dr Nicola Maney Dr Gary Reynolds Dr Anja Krippner-Heidenreich Professor Catharien Hilkens	Dendritic Cell Maturation and Survival Are Differentially Regulated by TNFR1 and TNFR2	2014
Dr Gary Reynolds Dr Faye Cooles Professor John Isaacs Professor Catharien Hilkens	Emerging immunotherapies for rheumatoid arthritis	2014
Dr Katherine Crossland Professor Simon Pearce Dr Mario Abinun Professor Timothy Cheetham Professor Catharien Hilkens et al.	Role of Aire in the Induction of Human Tolerogenic Dendritic Cells	2014
Dr Gillian Bell Dr Amy Anderson Julie Diboll Dr Rachel Harry Emerita Professor Elaine McColl et al.	Autologous Tolerogenic Dendritic Cells In Rheumatoid and Inflammatory Arthritis	2013
Dr Naomi McGovern Dr Laura Jardine Harriet Purvis Professor Catharien Hilkens Professor Matthew Collin et al.	IRF4 Transcription Factor-Dependent CD11b⁺ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses	2013
Dr Jeroen Stoop Chris Tibbitt Professor John Robinson Professor Catharien Hilkens	The choice of adjuvant determines the cytokine profile of T cells in proteoglycan-induced arthritis but does not influence disease severity	2013
Professor Catharien Hilkens Professor John Isaacs	Tolerogenic dendritic cell therapy for rheumatoid arthritis: where are we now?	2013
Dr Arthur Pratt Dr Daniel Swan Dr Sarah Richardson Gillian Wilson Professor Catharien Hilkens et al.	A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly anti-citrullinated peptide antibody-negative disease	2012
Dr Gillian Bell Dr Amy Anderson Dr Rachel Harry Dr Jeroen Stoop Professor Catharien Hilkens et al.	Autologous tolerogenic dendritic cells in rheumatoid arthritis	2012
Dr Joanna Collerton Dr Carmen Martin-Ruiz karen Davies Professor Catharien Hilkens Professor John Isaacs et al.	Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: Cross-sectional findings from the Newcastle 85+ Study	2012
Harriet Purvis Dr Amy Anderson Professor Catharien Hilkens	Human T helper 17 responses: the effect of T-cell density	2012
Dr Amy Anderson Dr Alice Lorenzi Dr Arthur Pratt Thomas Wooldridge Julie Diboll et al.	Immunity 12 years after alemtuzumab in RA: CD5+ B-cell depletion, thymus-dependent T-cell reconstitution and normal vaccine responses	2012
Dr Arthur Pratt Dr Sarah Richardson Gillian Wilson Professor Catharien Hilkens Professor David Young et al.	A Transcriptional Profile Present in CD4+T-Cells of Patients with Undifferentiated Arthritis Predicts the Future Development of Seronegative Rheumatoid Arthritis and Implicates IL-6 in Disease Evolution	2011
Dr Carmen Martin-Ruiz Emerita Professor Carol Jagger Dr Andrew Kingston Dr Joanna Collerton Professor Mike Catt et al.	Assessment of a large panel of candidate biomarkers of ageing in the Newcastle 85+ study	2011
Dr Jeroen Stoop Professor John Robinson Professor Catharien Hilkens	Developing tolerogenic dendritic cell therapy for rheumatoid arthritis: what can we learn from mouse models?	2011
Harriet Purvis Dr Amy Anderson Professor Catharien Hilkens	Human Th17 responses: the effect of T-cell density	2011
Dr Malcolm Brodlie Dr Michael McKean Dr Amy Anderson Professor Catharien Hilkens Professor Andrew Fisher et al.	Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease	2011
Professor Catharien Hilkens Professor John Isaacs	Development of dendritic cell-based immunotherapy for autoimmunity	2010
Dr Rachel Harry Dr Amy Anderson Professor John Isaacs Professor Catharien Hilkens	Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis	2010
Harriet Purvis Dr Jeroen Stoop Professor Jelena Mann Steven Woods Anne Kozijn et al.	Low strength T-cell activation promotes Th17 responses	2010
Dr Jeroen Stoop Professor Jelena Mann Steven Woods Anne Kozijn Professor Sophie Hambleton et al.	Low-strength T-cell activation promotes Th17 responses	2010
Dr Arthur Pratt Dr Daniel Swan Dr Sarah Richardson Professor Catharien Hilkens Professor David Young et al.	Peripheral Blood CD4 T Cell Gene Expression Profiles as Predictive Biomarkers in Early Arthritis	2010
Dr Nicola Maney Helen Baldwin Dr Anja Krippner-Heidenreich Professor Catharien Hilkens	Regulation of dendritic cell survival and function by tumour necrosis factor receptors 1 and 2	2010
Dr Jeroen Stoop Professor John Robinson Professor Catharien Hilkens	The choice of adjuvant determines the cytokine profile of T cells in proteoglycan induced arthritis	2010
Dr Jeroen Stoop Dr Rachel Harry Dr Alexei von Delwig Professor John Isaacs Professor John Robinson et al.	Therapeutic Effect of Tolerogenic Dendritic Cells in Established Collagen-Induced Arthritis Is Associated With a Reduction in Th17 Responses	2010
Helen Baldwin Dr Toshiko Ihara Professor John Isaacs Professor Catharien Hilkens	Tumour necrosis factor alpha blockade impairs dendritic cell survival and function in rheumatoid arthritis	2010
Dr Arthur Pratt Dr Daniel Swan Professor David Young Professor Catharien Hilkens Professor John Isaacs et al.	A High-Throughput Transcriptomics Approach to Biomarker Discover in Early Arthritis	2009
Dr Rachel Lakey Emeritus Professor Drew Rowan Professor John Isaacs Emeritus Professor Tim Cawston Professor Catharien Hilkens et al.	A novel paradigm for dendritic cells as effectors of cartilage destruction	2009
Dr Malcolm Brodlie Professor Catharien Hilkens Professor Christopher Ward	Airway epithelial cells as guardians of immune homeostasis?	2009
Professor Christopher Ward Julie Diboll Professor Andrew Fisher Dr Malcolm Brodlie Dr James Lordan et al.	Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells	2009
Professor Muzlifah Haniffa Dr Xiao Wang Dr Venetia Bigley Ian Dimmick Dr Trevor Booth et al.	Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation	2009
Dr Amy Anderson Dr David Swan Bethan Sayers Dr Rachel Harry Dr Angela Patterson et al.	LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells	2009
Dr Xiao Wang Dr Udo Holtick Professor Matthew Collin Professor Graham Jackson Professor Catharien Hilkens et al.	Regulatory T-Cell Suppression of CD8⁺ T-Cell-Mediated Graft-Versus-Host Reaction Requires Their Presence During Priming	2009
Dr Rachel Harry Dr Amy Anderson Dr Graham Raftery Professor John Isaacs Professor Catharien Hilkens et al.	Development of clinical-grade tolerogenic dendritic cells for the treatment of rheumatoid arthritis	2008
Dr Amy Anderson Bethan Sayers Professor Muzlifah Haniffa Dr David Swan Julie Diboll et al.	Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells	2008
Dr Jeroen Stoop Dr Alexei von Delwig Professor John Isaacs Professor John Robinson Professor Catharien Hilkens et al.	Immunotherapy with tolerogenic dendritic cells inhibits the progression of collagen-induced arthritis	2008
Dr Udo Holtick Dr Scott Marshall Dr Xiao Wang Professor Catharien Hilkens Professor Anne Dickinson et al.	Impact of Psoralen/UVA-treatment on survival, activation, and immunostimulatory capacity of monocyte-derived dendritic cells	2008
Dr Xiao Wang Professor Muzlifah Haniffa Dr Udo Holtick Professor Catharien Hilkens Professor Anne Dickinson et al.	Naturally occurring regulatory T-cells suppress CD8+lymphocyte induced graft-versus-host reactions in an in vitro human GvHD model	2008
Dr Amy Anderson Bethan Sayers Dr David Swan Professor John Isaacs Professor Catharien Hilkens et al.	Tolerogenic dendritic cell therapy for rheumatoid arthritis	2008
Professor Muzlifah Haniffa Dr Xiao Wang Dr Udo Holtick Dr Michelle Rae Professor John Isaacs et al.	Adult Human Fibroblasts Are Potent Immunoregulatory Cells and Functionally Equivalent to Mesenchymal Stem Cells	2007
Bethan Sayers Professor Muzlifah Haniffa Julie Diboll Professor John Isaacs Professor Catharien Hilkens et al.	Generation of dexamethasone and vitamin D3-treated human monocyte-derived dendritic cells with tolerogenic properties	2007
Dr Xiao Wang Dr Udo Holtick Suzanne Alshemali Professor Nick Reynolds Professor Anne Dickinson et al.	Human dermal broblasts ameliorate in vitro graft-versushost reactions and are functionally indistinguishable from bone marrow mesenchymal stromal cells	2007
Dr Udo Holtick Professor Catharien Hilkens Dr Xiao Wang Professor Anne Dickinson	Immature dendritic cells downregulate graft versus host reactions in the human skin explant model after co-culture with in vitro PUVA treated lymphocytes	2007
Professor Muzlifah Haniffa Dr Xiao Wang Dr Udo Holtick Dr Daniel Swan Professor Anne Dickinson et al.	Mesenchymal stem cells and fibroblasts have similar immunoregulatory properties in vitro but distinct gene expression profiles: Implications for cellular therapy	2007
Dr Amy Anderson Bethan Sayers Julie Diboll Professor John Isaacs Professor Catharien Hilkens et al.	Tolerogenic dendritic cells differentially modulate naïve and memory CD4⁺ T cells	2007
Suzanne Alshemali Dr Xiao Wang Professor Catharien Hilkens Professor Muzlifah Haniffa Professor Anne Dickinson et al.	Dermal dendritic cells but not Langerhans cells stimulate lymphocytes in an in vitro model of cutaneous graft-versus-host disease	2006
Dr Alexei von Delwig Professor Catharien Hilkens Professor John Isaacs Dr Helen Robertson Professor John Robinson et al.	Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice	2006
Dr Udo Holtick Dr Scott Marshall Dr Xiao Wang Professor Catharien Hilkens Professor Anne Dickinson et al.	Investigating the role of dendritic cells in extracorporeal photopheresis using an in vitro model	2006
Dr Udo Holtick Dr Scott Marshall Professor Muzlifah Haniffa Professor Catharien Hilkens Dr Xiao Wang et al.	Investigating the role of dendritic cells in extracorporeal photopheresis using an in vitro model	2006
Dr Udo Holtick Dr Scott Marshall Dr Xiao Wang Professor Catharien Hilkens Professor Anne Dickinson et al.	Modulation of dendritic cells in a human in vitro model of extracorporeal photopheresis	2006
Dr Udo Holtick Dr Scott Marshall Dr Xiao Wang Professor Catharien Hilkens Professor Anne Dickinson et al.	The fate of monocytes and monocyte-derived dendritic cells in an in vitro model of extracorporeal photopheresis	2006
Dr Udo Holtick Dr Scott Marshall Professor Catharien Hilkens Dr Xiao Wang Professor Anne Dickinson et al.	Examining the role of dendritic cells in extracorporeal photopheresis using an in vitro model	2005
Bethan Sayers Professor Muzlifah Haniffa Julie Diboll Professor John Isaacs Professor Catharien Hilkens et al.	Generation of dexamethasone and vitamin D3 treated human monocyte derived dendritic cells with tolerogenic properties	2005
Professor Catharien Hilkens	Sustained IL-12 Signaling Is Required for Th1 Development	2004
Professor Catharien Hilkens	α-type-1 polarized dendritic cells: A novel immunization tool with optimized CTL-inducing activity	2004
Professor Catharien Hilkens	Differential Responses to IFN-α Subtypes in Human T Cells and Dendritic Cells	2003
Professor Catharien Hilkens	Cell-type and Donor-specific Transcriptional Responses to Interferon-α: Use of customized gene arrays	2002
Professor Catharien Hilkens	A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130	2001
Professor Catharien Hilkens	How to deal with polarized Th2 cells: exploring the Achilles' heel	2001
Professor Catharien Hilkens	IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression	2001
Professor Catharien Hilkens	Atopic allergy: a failure of antigen-presenting cells to properly polarize helper T cells?	2000
Professor Catharien Hilkens	Final maturation of dendritic cells is associated with impaired responsiveness to IFN-gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells	1999
Professor Catharien Hilkens	T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal	1999
Professor Catharien Hilkens	The paradigm of type 1 and type 2 antigen-presenting cells. Implications for atopic allergy	1999
Professor Catharien Hilkens	High-level IL-12 production by human dendritic cells requires two signals	1998
Professor Catharien Hilkens	Prostaglandin E₂ induces the final maturation of IL-12-deficient CD1a⁺CD83⁺ dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation	1998
Professor Catharien Hilkens	The role of antigen-presenting cells in the regulation of allergen-specific T cell responses	1998
Professor Catharien Hilkens	Dendritic cells, obtained from peripheral blood precursors in the presence of PGE2, promote Th2 responses	1997
Professor Catharien Hilkens	Human dendritic cells require exogenous interleukin-12-inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype	1997
Professor Catharien Hilkens	IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells	1997
Professor Catharien Hilkens	Accessory cell-derived IL-12 and prostaglandin E2 determine the IFN-gamma level of activated human CD4+ T cells	1996
Professor Catharien Hilkens	Accessory cell-derived interleukin-12 and prostaglandin E2 determine the level of interferon-gamma produced by activated human CD4+ T cells	1996
Professor Catharien Hilkens	CD30 expression does not discriminate between human Th1- and Th2-type T cells	1996
Professor Catharien Hilkens	Lack of IL-12 signaling in human allergen-specific Th2 cells	1996
Professor Catharien Hilkens	Modulation of T-cell cytokine secretion by accessory cell-derived products	1996
Professor Catharien Hilkens	Production and modulation of T-cell cytokines in atopic allergy	1996
Professor Catharien Hilkens	Reduced IL-12 production by monocytes upon ultraviolet-B irradiation selectively limits activation of T helper-1 cells	1996
Professor Catharien Hilkens	Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit	1996
Professor Catharien Hilkens	The role of accessory cell products in the regulation of T cell cytokine production	1996
Professor Catharien Hilkens	Differential modulation of T helper type 1 (Th1) and T helper type 2 (Th2) cytokine secretion by prostaglandin E₂ critically depends on interleukin-2	1995
Professor Catharien Hilkens	Functional maturation of human naive T helper cells in the absence of accessory cells. Generation of IL-4-producing T helper cells does not require exogenous IL-4	1995
Professor Catharien Hilkens	Considerations in compiling a database of clinical test images	1992