Publications by Dr Joao Passos - ePrints

Browsing publications by Dr Joao Passos.

Newcastle Authors	Title	Year
Leena Habiballa Dr Antoneta Granic Dr Richard Dodds Susan Hillman Diana Jurk et al.	Determining the feasibility of characterising cellular senescence in human skeletal muscle and exploring associations with muscle morphology and physical function at different ages: findings from the MASS_Lifecourse Study	2023
Dr Rachael Redgrave Dr Emily Dookun Laura Booth Dr Maria Camacho Encina Dr Omowumi Folaranmi et al.	Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction	2023
Dr Anna Walaszczyk Dr Emily Dookun Dr Rachael Redgrave Dr Pawel Palmowski Dr Simon Tual-Chalot et al.	Therapeutic potential of navitoclax in age-related cardiovascular diseases	2022
Emily Dookun Dr Joao Passos Professor Helen Arthur Professor Gavin Richardson	Therapeutic Potential of Senolytics in Cardiovascular Disease	2022
Dr Arianna Bianchi Dr Letizia Marchetti Dr Hannah Paish Dr Kile Green Dr Dina Tiniakos et al.	Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis	2021
Dr Ed Fielder Dr Clare Tweedy Dr Caroline Wilson Professor Fiona Oakley Dr Fiona LeBeau et al.	Anti-inflammatory treatment rescues memory deficits during aging in nfkb1−/− mice	2020
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Pawel Palmowski Dr Simon Tual-Chalot et al.	Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery	2020
Dr Axel Kowald Dr Joao Passos Emeritus Professor Thomas Kirkwood	On the evolution of cellular senescence	2020
Stella Victorelli Dr Joao Passos	Telomeres: beacons of autocrine and paracrine DNA damage during skin aging	2020
Dr Ed Fielder Melanie Weigand Dr Diana Jurk Dr Joao Passos	Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk	2020
Dr Diana Jurk Dr Joao Passos Professor Thomas von Zglinicki	Cellular Senescence: Defining a Path Forward	2019
Dr Mikolaj Ogrodnik Hanna Salmonowicz Dr Diana Jurk Dr Joao Passos	Expansion and Cell-Cycle Arrest: Common Denominators of Cellular Senescence	2019
Rhys Anderson Anthony Lagnado Damien Maggiorani Dr Anna Walaszczyk Emily Dookun et al.	Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence	2019
Leena Habiballa Hanna Salmonowicz Dr Joao Passos	Mitochondria and cellular senescence: Implications for musculoskeletal ageing	2019
Dr James Chapman Dr Ed Fielder Dr Joao Passos	Mitochondrial dysfunction and cell senescence: deciphering a complex relationship	2019
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al.	Navitoclax eliminates senescence attenuating remodelling and improving outcome to cardiac ischemia-reperfusion injury	2019
Dr Mikolaj Ogrodnik Patrick Kruger Dr Ed Fielder Stella Victorelli Rifqha Ruswhandi et al.	Obesity-Induced Cellular Senescence Drives Anxiety And Impairs Neurogenesis	2019
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Dr Simon Tual-Chalot Professor Ioakim Spyridopoulos et al.	Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction.	2019
Clara Correia Melo Dr Jodie Birch Dr Ed Fielder Dr James Chapman Dr Anthony Lagnado et al.	Rapamycin improves healthspan but not inflammaging in nfkb1-/- mice	2019
Stella Victorelli Dr Joao Passos	Reactive Oxygen Species Detection in Senescent Cells	2019
Dr Joao Passos	Senescent cells evade immune clearance via HLA-E-mediated NK and CD8⁺ T cell inhibition	2019
Stella Victorelli Dr Anthony Lagnado Jessica Halim Dr James Chapman Dr Jodie Birch et al.	Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction	2019
Oliver Yausep Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot et al.	The Effects of Senolytics on Murine Cardiac Function and Morphology Post-Ischemia Reperfusion Injury	2019
Dr Jodie Birch Dr Joao Passos	The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype	2019
Dr Diana Jurk Dr Joao Passos	A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline	2018
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al.	Accumulation of cardiomyocyte senescence following ischaemia-reperfusion injury (IRI); a potential therapeutic target?	2018
Emily Dookun Dr Anna Walaszczyk Dr Rachael Redgrave Dr Simon Tual-Chalot Oliver Yausep et al.	Cardiomyocyte Senescence accumulates following Myocardial Infarction and Ischaemia-Reperfusion Injury.	2018
Rhys Anderson Professor Gavin Richardson Dr Joao Passos	Mechanisms driving the ageing heart	2018
Dr Jodie Birch Dr Joao Passos	Mitochondria, telomeres and cell senescence: Implications for lung ageing and disease	2018
Dr James Chapman Dr Joao Passos	Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis	2018
Damien Maggiorani Dr Joao Passos	Monoamine oxidase-A is a novel driver of stress-induced premature senescence through inhibition of parkin-mediated mitophagy	2018
Dr Bernadette Carroll Diego Manni Dr Rhoda Stefanatos Fiona Menzies Dr Graham Smith et al.	Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis	2018
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Dr Simon Tual-Chalot Rhys Anderson et al.	Senescence as a therapeutic target for myocardial ageing	2018
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Professor Ioakim Spyridopoulos Professor Helen Arthur et al.	Senescence contributes age related cardiac dysfunction	2018
Dr Anna Walaszczyk Emily Dookun Dr Rachael Redgrave Professor Ioakim Spyridopoulos Professor Helen Arthur et al.	Senescence contributes to reduced survival and impaired cardiac function following myocardial infraction in aged mice.	2018
Dr Joao Passos	Stress, cell senescence and organismal ageing	2018
Damien Maggiorani Professor Gavin Richardson Dr Joao Passos	Young vs Old mouse cardiomyocytes RNA-Seq.	2018
Dr Mikolaj Ogrodnik Dr Satomi Miwa Dr Dina Tiniakos Dr Caroline Wilson Professor Chris Day et al.	Cellular senescence drives age-dependent hepatic steatosis	2017
Dr Jodie Birch Dr Joao Passos	Cellular senescence mediates fibrotic pulmonary disease	2017
Dr Clara Correia Melo Dr Joao Passos	Depletion of mitochondria in mammalian cells through enforced mitophagy	2017
Hanna Salmonowicz Dr Joao Passos	Detecting senescence: a new method for an old pigment	2017
Dr Jodie Birch Dr Joao Passos	Targeting the SASP to combat ageing: Mitochondria as possible intracellular allies?	2017
Stella Victorelli Dr Joao Passos	Telomeres and Cell Senescence - Size Matters Not	2017
Dr Bernadette Carroll Gisela Otten Matthew Ratcliff Dr Graham Smith Dr Joao Passos et al.	Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity	2016
Dr Irina Neganova Dr Evgeniya Shmeleva Dr Jennifer Munkley Dr Valeria Chichagova Dr George Anyfantis et al.	JNK/SAPK signalling is essential for efficient reprogramming of human fibroblasts to induced pluripotent stem cells	2016
Dr Clara Correia Melo Francisco Marques Rhys Anderson Dr Graeme Hewitt Dr Bernadette Carroll et al.	Mitochondria are required for pro-ageing features of the senescent phenotype	2016
Dr Clara Correia Melo Dr Jodie Birch Dr Joao Passos	Powering senescence: The ugly side of mitochondria	2016
Dr Graeme Hewitt Dr Bernadette Carroll Dr Clara Correia Melo Mikolaj Ogrodnik Dr Glyn Nelson et al.	SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair	2016
Dr Jodie Birch Stella Victorelli Rhys Anderson Kasim Jiwa Dr Elizabeth Moisey et al.	Telomere Dysfunction and Senescence-associated Pathways in Bronchiectasis	2016
Professor Bob Anderson Dr Simon Tual-Chalot Dr Rachael Redgrave Rebecca Dodds Dr Andrew Owens et al.	The role of cardiomyocyte senescence and regeneration in Ageing	2016
Dr Jodie Birch Rhys Anderson Clara Correia Melo Dr Diana Jurk Dr Graeme Hewitt et al.	DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease	2015
Dr Clara Correia Melo Dr Joao Passos	Mitochondria: Are they causal players in cellular senescence?	2015
Dr Caroline Wilson Dr Diana Jurk Nicola Fullard Paul Banks Dr Agata Page et al.	NFkB1 is a suppressor of neutrophil-driven hepatocellular carcinoma	2015
Dr Irina Neganova Dr Katarzyna Tilgner Dr Adriana Buskin Iliana Paraskevopoulou Dr Stuart Atkinson et al.	CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cells	2014
Dr Diana Jurk Dr Caroline Wilson Dr Joao Passos Professor Fiona Oakley Clara Correia Melo et al.	Chronic inflammation induces telomere dysfunction and accelerates ageing in mice	2014
Dr Graeme Hewitt Professor Thomas von Zglinicki Dr Joao Passos	Cell sorting of young and senescent cells	2013
Professor Viktor Korolchuk Dr Joao Passos	Lysosome-mediated processing of chromatin in senescence	2013
Jen Birch Dr Gavin Johnson Professor Christopher Ward Dr John Taylor Dr Joao Passos et al.	Small Airway Epithelial Cell Senescence Present in COPD and Bronchiectasis?	2013
Dr Conor Lawless Dr Diana Jurk Dr Colin Gillespie Dr Daryl Shanley Dr Gabriele Saretzki et al.	A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations	2012
Dr Joao Passos Professor Thomas von Zglinicki	Mitochondrial dysfunction and cell senescence - skin deep into mammalian aging	2012
Dr Graeme Hewitt Dr Diana Jurk Francisco Marques Clara Correia Melo Dr Timothy Hardy et al.	Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence	2012
Dr Irina Neganova Dr Stuart Atkinson Dr Joao Passos Professor Thomas von Zglinicki Professor Lyle Armstrong et al.	An Important Role for CDK2 in G1 to S Checkpoint Activation and DNA Damage Response in Human Embryonic Stem Cells	2011
Dr Joao Passos Dr Glyn Nelson Dr Cedric Simillion Dr Carole Proctor Dr Satomi Miwa et al.	Feedback between p21 and reactive oxygen production is necessary for cell senescence	2010
Dr Conor Lawless Dr Diana Jurk Alina Merz Professor Thomas von Zglinicki Dr Joao Passos et al.	Quantitative assessment of markers for cell senescence	2010
Dr Joao Passos Dr Cedric Simillion Dr Jennifer Hallinan Professor Anil Wipat Professor Thomas von Zglinicki et al.	Cellular senescence: Unravelling complexity	2009
Dr Shaheda Ahmed Dr Joao Passos Matthew Birket Professor Thomas von Zglinicki	Telomerase protects mitochondria and lowers oxidative stress	2009
Matthew Birket Dr Joao Passos Professor Thomas von Zglinicki Professor Mark Birch-Machin	The Relationship between the Aging- and Photo-Dependent T414G Mitochondrial DNA Mutation with Cellular Senescence and Reactive Oxygen Species Production in Cultured Skin Fibroblasts	2009
Dr Gabriele Saretzki Theresia Walter Dr Joao Passos Dr Rebecca Stewart Dr Simon Hoare et al.	Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells	2008
Matthew Birket Dr Joao Passos Professor Thomas von Zglinicki Professor Mark Birch-Machin	Investigation of the relationship between the ageing- and photodependent T414G mitochondrial DNA mutation with cellular senescence and reactive oxygen species production in cultured skin fibroblasts	2008
Dr Joao Passos Dr Sharon Olijslagers Professor Thomas von Zglinicki	Mitochondrial dysfunction is a possible cause of accelerated senescence of mesothelial cells exposed to high glucose	2008
Dr Joao Passos	Portugal gets ready to embrace ageing research	2008
Dr Joao Passos Professor Thomas von Zglinicki	Retrograde response, oxidative stress and cellular senescence	2008
Dr Joao Passos	Role of respiration and glutathione in cadmium-induced oxidative stress in Escherichia coli K-12	2008
Avgi Tsolou Dr Joao Passos Dr Glyn Nelson Dr Yasumichi Arai Professor Thomas von Zglinicki et al.	ssDNA fragments induce cell senescence by telomere uncapping	2008
Dr Saeed Ahmed Dr Joao Passos Matthew Birket Dr Heiko Peters Professor Mark Birch-Machin et al.	Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress	2008
Dr Joao Passos Dr Glyn Nelson Professor Thomas von Zglinicki	Telomeres, Senescence, Oxidative stress and heterogeneity	2008
Dr Joao Passos Dr Gabriele Saretzki Professor Thomas von Zglinicki	DNA damage in telomeres and mitochondria during cellular senescence: Is there a connection?	2007
Dr Joao Passos Professor Thomas von Zglinicki	Methods for cell sorting of young and senescent cells	2007
Dr Joao Passos Professor Thomas von Zglinicki Emeritus Professor Thomas Kirkwood	Mitochondria and ageing: Winning and losing in the numbers game	2007
Professor Thomas von Zglinicki Dr Joao Passos Dr Gabriele Saretzki	Mitochondria and telomeres: Strange bedfellows in cell senescence	2007
Dr Joao Passos Dr Gabriele Saretzki Dr Saeed Ahmed Dr Glyn Nelson Torsten Richter et al.	Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence	2007
Dr Hamid Reza Soleimanpour Lichaei Dr Joao Passos Dr Mateusz Wydro Dr Joanna Rorbach Dr Richard Temperley et al.	mtRF1a Is a Human Mitochondrial Translation Release Factor Decoding the Major Termination Codons UAA and UAG	2007
Dr Joao Passos Dr Glyn Nelson Dr Gabriele Saretzki Professor Thomas von Zglinicki	Oxygen free radicals in senescence: Are they signal transducers?	2007
Dr Joao Passos Dr Sharon Olijslagers Dr Gabriele Saretzki Dr Carmen Martin-Ruiz Professor Thomas von Zglinicki et al.	Premature senescence of mesothelial cells is associated with non-telomeric DNA damage	2007
Dr Carmen Martin-Ruiz Dr Joao Passos Professor Thomas von Zglinicki	Extended lifespan and long telomeres in rectal fibroblasts from late-onset ulcerative colitis patients	2006
Dr Joao Passos Dr Gabriele Saretzki Professor Thomas von Zglinicki	Mechanisms and role of oxidative damage to telomeres	2006
Dr Joao Passos Dr Gabriele Saretzki Professor Thomas von Zglinicki	Mechanisms and role of oxidative damage to telomeres	2006
Dr Joao Passos Professor Thomas von Zglinicki Dr Gabriele Saretzki	Mitochondrial dysfunction and cell senescence: Cause or consequence?	2006
Dr Joao Passos Professor Thomas von Zglinicki	Oxygen free radicals in cell senescence: Are they signal transducers?	2006
Dr Joao Passos Professor Thomas von Zglinicki	Mitochondria, telomeres and cell senescence	2005
Dr Joao Passos	Strain PM2, a novel methylotrophic fluorescent Pseudomonas sp	2003