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Browsing publications by Professor Derek Manas.

Newcastle AuthorsTitleYearFull text
Professor Derek Manas
Guidelines Development Group for the British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma2024
Abdullah Malik
David Talbot
Steven White
David Rix
Professor Derek Manas
et al.
Incidental lymphadenopathy in renal transplantation2024
Daniel Saleh
Professor Derek Manas
International consensus recommendations on face transplantation: A 2-step Delphi study2024
Professor Derek Manas
Long-Term Kidney Transplant Survival Across the Globe2024
Dr Balaji Mahendran
Dr Sam Tingle
Abdullah Malik
Rodrigo Figueiredo
John Hammond
et al.
Racial disparities in outcomes after liver transplantation in the UK: registry analysis2024
Steven White
Professor Derek Manas
Response to “Following the Flow: Changes in Organ Preservation Methods Require Changes in Our Data Collection”2024
Dr Sam Tingle
David Rix
Professor Derek Manas
Professor Colin Wilson
Routine intraoperative ureteric stenting for kidney transplant recipients2024
Professor Derek Manas
Gourab Sen
Severe Cholestasis Predicts Recurrent Primary Sclerosing Cholangitis Following Liver Transplantation2024
Abdullah Malik
Professor Derek Manas
Surgical management, including the role of transplantation, for intrahepatic and peri-hilar cholangiocarcinoma2024
Abdullah Malik
Dr Sam Tingle
Dr Balaji Mahendran
Professor Derek Manas
Professor Colin Wilson
et al.
The impact of time to death in donors after circulatory death on recipient outcome in simultaneous pancreas-kidney transplantation2024
Dr Guy MacGowan
S Clark
Dr Zdenka Reinhardt
Professor Derek Manas
A national pilot of donation after circulatory death (DCD) heart transplantation within the United Kingdom2023
Professor Derek Manas
British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma2023
Professor Derek Manas
Where Are We Now with Liver Transplantation in Neuroendocrine Neoplasms? The Place of Liver Transplantation for Grades 1 and 2 Well-Differentiated Unresectable Liver Metastatic Neuroendocrine Tumours2023
Professor Derek Manas
Steven White
Adjuvant chemotherapy for perihilar cholangiocarcinoma: A population-based comparative cohort study2022
Nathania Sutandi
Gourab Sen
John Hammond
Professor Derek Manas
Jeremy French
et al.
Comparative analysis of open, laparoscopic and robotic distal pancreatic resection: The United Kingdom′s first single-centre experience2022
Dr Daniel Geh
Robyn Watson
Gourab Sen
Jeremy French
John Hammond
et al.
COVID-19 and liver cancer: Lost patients and larger tumours2022
Professor Kofi Oppong
Dr Manu Nayar
Dr Beate Haugk
Dr Antony Darne
Professor Derek Manas
et al.
Impact of prior biliary stenting on diagnostic performance of endoscopic ultrasound for mesenteric vascular staging in patients with head of pancreas and periampullary malignancy2022
Abdullah Malik
Professor Sanjay Pandanaboyana
Gourab Sen
Professor Stuart McPherson
Dr Jess Dyson
et al.
Risk factors for decompensation and death following umbilical hernia repair in patients with end-stage liver disease2022
Professor Helen Reeves
Professor Derek Manas
Dr Peter Littler
Selective internal radiation therapy (SIRT) for hepatocellular carcinoma (HCC): Informing clinical practice for multidisciplinary teams in England2022
Professor Derek Manas
Professor James Shaw
Professor Colin Wilson
Steven White
105.2: Pancreas and Islet Transplantation in the UK During the COVID-19 Era2021
Dr Steven Masson
Professor Derek Manas
A coordinated national UK liver transplant program response, prioritizing waitlist recipients with the highest need, provided excellent outcomes during the first wave of the COVID-19 pandemic2021
Professor Derek Manas
Steven White
A network meta-analysis of induction immunosuppression for simultaneous pancreas-kidney transplant from randomized clinical trials2021
Matt Byrne
Dr Avinash Sewpaul
Dr Sam Tingle
Emily Thompson
Marcus Brookes
et al.
Early protocol computer tomography and endovascular interventions in pancreas transplantation2021
Dr Thomas Berney
Professor Derek Manas
Steven White
Impact of SARS-CoV-2 on pancreas transplant activity: Survey of international surgeons2021
Dr Peter Littler
Gourab Sen
Professor Derek Manas
Professor Sanjay Pandanaboyana
Margin Accentuation Irreversible Electroporation in Stage III Pancreatic Cancer: A Systematic Review2021
John Hammond
Steven White
Jeremy French
Professor Derek Manas
Professor Sanjay Pandanaboyana
et al.
Meta-analysis of survival outcomes following surgical and non surgical treatments for colorectal cancer metastasis to the lung2021
Dr Sam Tingle
Dr Emily Thompson
Rodrigo Figueiredo
Dr Mark Hudson
Gourab Sen
et al.
Risk factors and impact of early anastomotic biliary complications after liver transplantation: UK registry analysis2021
Jeremy French
Dr Colin Wilson
Professor Derek Manas
Steven White
Professor Sanjay Pandanaboyana
et al.
Systematic review and meta-analysis of risk factors of postoperative pancreatic fistula after distal pancreatectomy in the era of 2016 International Study Group pancreatic fistula definition2021
Dr Ruth Owen
Dr Emily Thompson
Dr Sam Tingle
Dr Ibrahim Ibrahim
Professor Derek Manas
et al.
Too Fat for Transplant? The Impact of Recipient BMI on Pancreas Transplant Outcomes2021
Professor Helen Reeves
Professor Derek Manas
Steven White
Treatment strategies for early stage hepatocellular carcinoma: a systematic review and network meta-analysis of randomised clinical trials2021
Professor Derek Manas
Steven White
A systematic review and network meta-analysis of different surgical approaches for pancreaticoduodenectomy2020
Professor Colin Wilson
Gourab Sen
John Hammond
Jeremy French
Professor Derek Manas
et al.
A systematic review and network meta-analysis of parenchymal transection techniques during hepatectomy: an appraisal of current randomised controlled trials2020
Professor Derek Manas
Steven White
A systematic review and network meta-analysis of phase III randomised controlled trials for adjuvant therapy following resection of pancreatic ductal adenocarcinoma (PDAC)2020
Dr Jack Leslie
Dr Marina Garcia Macia
Dr Saimir Luli
Dr Julie Worrell
William Reilly
et al.
c-Rel orchestrates energy-dependant epithelial and macrophage reprogramming in fibrosis2020
Gourab Sen
John Hammond
Jeremy French
Professor Colin Wilson
Professor Derek Manas
et al.
Haemostatic Efficacy of Topical Agents During Liver Resection: A Network Meta-Analysis of Randomised Trials2020
Sebastian Mafeld
Dr Peter Littler
Dr Hannah Hayhurst
Professor Derek Manas
John Moir
et al.
Liver Resection After Selective Internal Radiation Therapy with Yttrium-90: Safety and Outcomes2020
Jeremy French
Professor Derek Manas
John Hammond
Professor Sanjay Pandanaboyana
Meta-Analysis and Meta-Regression of Risk Factors for Surgical Site Infections in Hepatic and Pancreatic Resection2020
Professor Derek Manas
Steven White
Robotic Versus Conventional Laparoscopic Liver Resections: A Systematic Review and Meta-Analysis2020
Professor Derek Manas
Steven White
Robotic versus conventional laparoscopic pancreaticoduodenectomy a systematic review and meta-analysis2020
John Moir
Anna Long
Dr Beate Haugk
Jeremy French
Richard Charnley
et al.
Therapeutic Strategies Toward Lactate Dehydrogenase Within the Tumor Microenvironment of Pancreatic Cancer2020
Dr Hannah Paish
Lee Reed
Helen Brown
Mark Bryan
Dr Olivier Govaere
et al.
A bioreactor technology for modelling fibrosis in human and rodent precision-cut liver slices2019
Sebastian Mafeld
Professor Helen Reeves
Professor Derek Manas
Dr Peter Littler
Early Experience of Trans-arterial Chemo-Embolisation for Hepatocellular Carcinoma with a Novel Radiopaque Bead2019
Dr Abdullah Malik
Dr Steven Masson
Dr Mark Hudson
Professor Derek Manas
Impact of Regional Organ Sharing and Allocation in the UK Northern Liver Alliance on Waiting Time to Liver Transplantation and Waitlist Survival2019
Professor Derek Manas
Gourab Sen
Incidence and outcome of colorectal cancer in liver transplant recipients: A national, multicentre analysis on 8115 patients2019
Dr Aimen Amer
Professor Colin Wilson
Professor Derek Manas
Liver transplantation for unresectable malignancies: Beyond hepatocellular carcinoma2019
Dr Bill Scott
Professor Derek Manas
Professor James Shaw
Oxygen Perfusion (Persufflation) of Human Pancreata Enhances Insulin Secretion and Attenuates Islet Proinflammatory Signaling2019
David Talbot
Professor Derek Manas
Steven White
Preemptive appendicectomy at the time of pancreas transplantation: Is it necessary?2019
Abdullah Malik
Stuart Robinson
Jeremy French
Gourab Sen
Professor Colin Wilson
et al.
Surgery for Hilar cholangiocarcinoma: the Newcastle upon Tyne Liver Unit experience2019
Dr Aimen Amer
Gourab Sen
Jeremy French
Professor Colin Wilson
Professor Derek Manas
et al.
The association of pregnane X receptor activation with outcomes after liver transplantation—A retrospective study2019
Sebastian Mafeld
Dr Steven Masson
Aimen Amer
Professor Colin Wilson
Professor Derek Manas
et al.
Treatment of Visceral Transplant Pseudoaneurysms Using Physician-Modified Fenestrated Stent Grafts: Initial Experience2019
Dr Emily Thompson
Ellie Irwin
Dr Ibrahim Ibrahim
Dr Sam Tingle
Steven White
et al.
UK registry analysis of donor substance misuse and outcomes following pancreas transplantation2019
Professor Derek Manas
Yttrium-90 Transarterial Radioembolization for Chemotherapy-Refractory Intrahepatic Cholangiocarcinoma: A Prospective, Observational Study2019
Professor Derek Manas
Analysis of a National Programme for Selective Internal Radiation Therapy for Colorectal Cancer Liver Metastases2018
Abdullah Malik
Dr Jeffry Hogg
Professor John Lunec
Professor Derek Manas
Jeremy French
et al.
External validation of nomograms for prediction of survival outcome in retroperitoneal sarcoma using the North East England cohort2018
Sebastian Mafeld
Jeremy French
Dr Dina Tiniakos
Dr Beate Haugk
Professor Derek Manas
et al.
Fibrolamellar Hepatocellular Carcinoma: Treatment with Yttrium-90 and Subsequent Surgical Resection2018
Dr Jane Margetts
Laura Ogle
Dr Anthony Chan
Dr David Jamieson
Dr Catherine Willoughby
et al.
Neutrophils: driving progression and poor prognosis in hepatocellular carcinoma?2018
Dr Louise Coats
Dr John O'Sullivan
Dr David Crossland
Dr Beate Haugk
Dr Mark Hudson
et al.
Combined heart-liver transplantation for failing Fontan circulation in a late survivor with single-ventricle physiology.2017
Professor Derek Manas
Professor Helen Reeves
Comparing clinical presentations, treatments and outcomes of hepatocellular carcinoma due to hepatitis C and non-alcoholic fatty liver disease2017
Dr Avinash Sewpaul
Rodrigo Figueiredo
Dr Jakub Chmelo
Steven White
Professor Derek Manas
et al.
High postoperative tacrolimus variability predisposes to early pancreas graft loss2017
Professor Derek Manas
The Post-SIR-Spheres Surgery Study (P4S): Retrospective Analysis of Safety Following Hepatic Resection or Transplantation in Patients Previously Treated with Selective Internal Radiation Therapy with Yttrium-90 Resin Microspheres2017
Dr Bill Scott
Minna Honkanen-Scott
Dr Julian De Havilland
Professor Derek Manas
Professor James Shaw
et al.
Diversifying the Indications for Pancreas Resection and Autologous Islet Cell Transplantation (IAT) in both Adults and Children2016
Minna Honkanen-Scott
Dr Julian De Havilland
Professor Derek Manas
Professor James Shaw
Professor Anne Dickinson
et al.
Expanding the indications for pancreas resection and autologous islet cell transplantation (IAT) in both adults and children2016
Stuart Robinson
Jeremy French
Professor Derek Manas
Richard Charnley
Steven White
et al.
First UK experience of robotic versus laparoscopic distal pancreatectomy2016
Dr Mat Elameer
Jeremy French
Professor Derek Manas
Professor Helen Reeves
Dr Peter Littler
et al.
Implementation of a one-stop multidisciplinary clinic for liver-directed therapy in patients with primary or secondary liver malignancies2016
John Moir
Dr Peter Littler
Dr Kate Sumpter
Steven White
Jeremy French
et al.
Initial experience in irreversible electroporation for the treatment of locally advanced unresectable pancreatic cancer2016
Professor Helen Reeves
Professor Derek Manas
Long-term impact of liver function on curative therapy for hepatocellular carcinoma: application of the ALBI grade2016
John Moir
Professor Derek Mann
Professor Jelena Mann
Richard Charnley
Professor Derek Manas
et al.
Metabolic relationships within the tumour microenvironment of pancreatic ductal adenocarcinoma - pancreatic stellate cells induce glycolysis in cancer cells2016
Stuart Robinson
Professor Derek Mann
Professor Derek Manas
Professor Fiona Oakley
Professor Jelena Mann
et al.
Response to 'Comment on 'The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndrome''2016
Dr Jeffry Hogg
Professor Derek Manas
Dr Daniela Lee
Dr Petra Dildey
Professor John Lunec
et al.
Surgical outcome and patterns of recurrence for retroperitoneal sarcoma at a single centre.2016
John Moir
Professor Derek Mann
Professor Jelena Mann
Richard Charnley
Professor Derek Manas
et al.
The effect of monocarboxylate transporter 1 inhibition in the tumour microenvironment of pancreatic ductal adenocarcinoma2016
Dr Colin Wilson
Jeremy French
Richard Charnley
Professor Derek Manas
Gourab Sen
et al.
Trends in Gall bladder surgery in England - a decade of progress2016
Dr Colin Wilson
Jeremy French
Gourab Sen
Professor Derek Manas
Trends in Liver surgery in England - a decade and beyond2016
Gourab Sen
Dr Mark Hudson
Professor Derek Manas
Umbilical Hernia Repair in Cirrhosis: Outcomes and Prognostic Factors in a Liver Transplant Unit2016
Dr Gus Brooks
Dr Aaron Liew
Dr Helen Marshall
Dr Ali Aldibbiat
Professor Neil Sheerin
et al.
De Novo Donor-Specific HLA Antibodies Are Associated With Rapid Loss of Graft Function Following Islet Transplantation in Type 1 Diabetes2015
Liam Cornell
Dr Joanne Martin
Laura Ogle
Dr Catherine Willoughby
Dr Despina Televantou
et al.
DNA-PK-A Candidate Driver of Hepatocarcinogenesis and Tissue Biomarker That Predicts Response to Treatment and Survival2015
Dr Jess Dyson
Dr Steven Masson
Professor Stuart McPherson
Professor Derek Manas
Dr Mark Hudson
et al.
Experience of Using Advagraf in a Single Liver Transplant Centre in the United Kingdom2015
Dr Rachael Coates
Dr Faryal Afridi
Steven White
Professor Derek Manas
David Talbot
et al.
Procurement Damage of DCD Pancreas Alone Grafts is it a Problem? A Single Centre Experience2015
Professor Derek Manas
Darius Mirza
Gourab Sen
Risk factors for recurrent primary sclerosing cholangitis after liver transplantation2015
John Moir
Steven White
Dr Peter Littler
Professor Derek Manas
Jeremy French
et al.
Selective internal radiation therapy for liver malignancies2015
Dr Julian De Havilland
Minna Honkanen-Scott
Richard Charnley
Professor Derek Manas
Professor James Shaw
et al.
Successful autologous islet transplantation post-frey's procedure using a side-vented 'therapeutic infusion needle' for improved enzyme delivery2015
John Moir
Steven White
Jeremy French
Dr Peter Littler
Professor Derek Manas
et al.
Systematic review of irreversible electroporation in the management of pancreatic cancer2015
Stuart Robinson
Jeremy French
Gourab Sen
Richard Charnley
Professor Derek Manas
et al.
The impact of open colectomy on resection of colorectal liver metastases2015
Dr Abigail Vallance
Professor Colin Wilson
Professor Derek Manas
Steven White
Total pancreatectomy and islet autotransplantation for chronic pancreatitis2015
Stuart Robinson
Dr Steven Masson
Dr Mark Hudson
Professor Derek Manas
Umbilical hernia repair in cirrhosis: outcomes and prognostic factors in a liver transplant unit2015
Steven White
Jeremy French
Professor Derek Manas
A Cadaver Lab Training Facility to Facilitate Laparoscopic Liver Resection2014
Dr Jess Dyson
Dr Mark Hudson
Professor Derek Manas
Dr Steven Masson
A Positive Complement Dependent Cytotoxic (CDC) Crossmatch Does Not Impact on Patient Survival or Increase the Risk of Acute Cellular Rejection, or Biliary Strictures after Liver Transplantation2014
Nikil Vasdev
Professor Naeem Soomro
David Rix
Bryon Jaques
Professor Derek Manas
et al.
A prospective randomised paired trial of sirolimus versus tacrolimus as primary immunosuppression following non-heart beating donor kidney transplantation2014
Dr Shafiq Rehman
Jeremy French
Professor Derek Manas
Steven White
A single centre experience of first "one hundred laparoscopic liver resections"2014
Professor Kofi Oppong
Professor David Jones
Richard Charnley
Professor Derek Manas
Bryon Jaques
et al.
Autoimmune Pancreatitis - Diagnosis, Management and Longterm Follow-up2014
Stuart Robinson
John Moir
Dr Ashraf Azzabi
Professor Derek Manas
Steven White
et al.
Defining the optimal conversion chemotherapy regimen for patients with inoperable liver only metastases from colorectal cancer - a systematic review and meta-analysis2014
Richard Charnley
Bryon Jaques
Steven White
Jeremy French
Professor Derek Manas
et al.
Endoscopic ultrasound in patients with normal liver blood tests and unexplained dilatation of common bile duct and or pancreatic duct2014
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
Folfox induced sinusoidal obstruction syndrome (SOS) is a potentially reversible condition2014
Dr Jess Dyson
Dr Dipanker Chattopadhyay
Rajiv Lochan Jayadeva
Dr Imran Patanwala
Mike Cole
et al.
Hepatocellular cancer: The impact of obesity, type 2 diabetes and a multidisciplinary team2014
Bryon Jaques
Professor Derek Manas
Richard Charnley
Jeremy French
Steven White
et al.
Oncological Feasibility of Laparoscopic Distal Pancreatectomy for Adenocarcinoma: A Single-Institution Comparative Study2014
Professor Derek Manas
Steven White
Outcomes Following Pancreas Retransplantation: The United Kingdom Experience2014
Dr Shafiq Rehman
Jeremy French
Professor Derek Manas
Gourab Sen
Steven White
et al.
Role of prophylactic octreotide in pancreaticoduodenectomy patients: single centre comparative study2014
Professor Derek Manas
Dr Beate Haugk
Professor John Dark
Bryon Jaques
Simultaneous liver resection and double cardiac valve replacement. A case report2014
John Moir
Steven White
Jeremy French
Dr Peter Littler
Professor Derek Manas
et al.
Systematic review of irreversible electroporation in the treatment of advanced pancreatic cancer2014
Sandra Robinson
Colin Wilson
Professor Derek Manas
The role of cardiopulmonary bypass in the management of retrohepatic vena cava injury - A case report and review of the literature2014
Dr Abigail Vallance
Sandra Robinson
Professor Derek Manas
Jeremy French
Richard Charnley
et al.
Treatment outcomes of foregut visceral arterial aneurysms (FVAA)2014
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
An experimental MODEL study to investigate the pathogenesis of oxaliplatin-induced liver injury2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
An experimental study to identify the potential role of pharmacogenomics in determining the occurrence of oxaliplatin-induced liver injury2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Antioxidant therapy is able to prevent the development of oxaliplatin induced sinusoidal obstruction syndrome2013
Dr Christopher Snowden
Dr James Prentis
Dr Helen Anderson
Professor Derek Manas
Professor Mike Trenell
et al.
Cardiorespiratory Fitness Predicts Mortality and Hospital Length of Stay After Major Elective Surgery in Older People2013
Mohamed Noormohamed
Professor Matthew Wright
Dr David Cowie
Susan Stamp
David Talbot
et al.
Extracorporeal membrane oxygenation for resuscitation of deceased cardiac donor livers for hepatocyte isolation2013
Dr Helen Marshall
Professor James Shaw
Professor Derek Manas
Human Pancreas Persufflation Ameliorates Hypoxia-Induced Impairment of Islet Function Post-Isolation2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Identification of molecular pathways implicated in the pathogenesis of oxaliplatin induced sinusoidal obstruction syndrome2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Is FOLFOX induced sinusoidal obstruction syndrome (SOS) a potentially reversible condition?2013
Steven White
Dr Rachael Coates
Professor Derek Manas
Liver damage during organ donor procurement in donation after circulatory death compared with donation after brain death2013
Professor Colin Wilson
David Rix
Professor Derek Manas
Routine intraoperative ureteric stenting for kidney transplant recipients2013
John Asher
Professor Colin Wilson
David Talbot
Professor Derek Manas
Steven White
et al.
Successful Endovascular Salvage of a Pancreatic Graft After a Venous Thrombosis: Case Report and Literature Review2013
Stuart Robinson
Professor Derek Mann
Professor Derek Manas
Professor Fiona Oakley
Professor Jelena Mann
et al.
The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndrome2013
Dr Ased Ali
Professor John Dark
Professor Derek Manas
David Thomas
The surgical management and prognosis of renal cell cancer with IVC tumor thrombus: 15-Years of experience using a multi-specialty approach at a single UK referral center2013
Dr Colin Wilson
Nikil Vasdev
Professor Derek Manas
David Talbot
David Rix
et al.
Therapeutic kidney donation: A potential source of precious organs2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Alastair Burt
Professor Derek Mann
et al.
An experimental study to determine the pathogenesis of oxaliplatin induced sinusoidal obstruction syndrome2012
Stuart Robinson
Professor Derek Manas
Professor Alastair Burt
Steven White
Biliary dysfunction in patients with sinusoidal obstruction syndrome2012
Dr Shafiq Rehman
Stuart Robinson
Dr Beate Haugk
Professor Derek Manas
Steven White
et al.
Biliary invasion in colorectal liver metastasis—does it matter?2012
Stuart Robinson
Dr Caroline Wilson
Professor Alastair Burt
Professor Derek Manas
Steven White
et al.
Chemotherapy associated liver injury: a systematic review and meta-analysis2012
Stuart Robinson
Professor Colin Wilson
Professor Alastair Burt
Professor Derek Manas
Steven White
et al.
Chemotherapy-Associated Liver Injury in Patients with Colorectal Liver Metastases: A Systematic Review and Meta-analysis2012
Dr Shafiq Rehman
Dr Abigail Vallance
Stuart Robinson
Professor Derek Manas
Steven White
et al.
Colorectal liver metastasis (CRLM): increasing role of laparoscopic liver resection-a single unit comparative analysis2012
Stuart Robinson
Professor Jelena Mann
Professor Alastair Burt
Professor Derek Manas
Professor Derek Mann
et al.
Does a pro-thrombotic environment contribute to the development of chemotherapy associated liver injury in patients with colorectal liver metastases?2012
Dr Abigail Vallance
Professor Derek Manas
Dr James Prentis
Dr Christopher Snowden
Richard Charnley
et al.
Double bypass for inoperable pancreatic malignancy at laparotomy: postoperative complications and long-term outcome2012
Dr Christopher Snowden
Dr James Prentis
Dr Luke Holmes
Bryon Jaques
Steven White
et al.
Effects of low cardiopulmonary reserve on pancreatic leak following pancreaticoduodenectomy2012
Dr Matthew Thomas
Professor Colin Wilson
Professor Derek Manas
Professor Mark Walker
Professor James Shaw
et al.
Endoscopic Botulinum Toxin Injection for the Treatment of Diabetic Gastropathy in Pancreas and Islet-cell Transplant Patients2012
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Expression of the copper export transporter atpase 7B correlates with tissue specific injury in a murine model of colorectal liver metastases2012
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Gene expression in oxaliplatin related sinusoidal obstruction syndrome2012
Stuart Robinson
Dr Alexei von Delwig
Professor Derek Manas
Steven White
Immunotherapy for treating metastatic colorectal cancer2012
Douglas Hui
Stuart Robinson
Dr Gillian Patman
Professor Derek Manas
Professor Helen Reeves
et al.
KLF6 splice variant 1 in patients with colorectal liver metastasis correlates with a higher clinical risk score2012
Dr Abigail Vallance
Dr Shafiq Rehman
Stuart Robinson
Richard Charnley
Bryon Jaques
et al.
Prognostic factors influencing survival after liver resection for colorectal metastasis2012
Dr James Prentis
Professor Derek Manas
Professor Mike Trenell
Dr Mark Hudson
Dr Christopher Snowden
et al.
Submaximal cardiopulmonary exercise testing predicts 90-day survival after liver transplantation2012
Dr Aimen Amer
Professor Derek Manas
Professor Matthew Wright
Steven White
The effect of hypoxic stress on activated hepatic stellate cell chemotaxis in-vitro2012
Dr Ali Aldibbiat
Dr Graham Holliman
Linda Ferguson
Kenneth Brigham
Dr Josephine Wardle
et al.
Validation of Islet Transport From a Geographically Distant Isolation Center Enabling Equitable Access and National Health Service Funding of a Clinical Islet Transplant Program for England2012
John Asher
Jeremy French
Bryon Jaques
Professor Derek Manas
Steven White
et al.
Beware the pancreas transplant recipient with elevated fibrinogen and hypotension.2011
Dr James Prentis
David Jones
Professor Derek Manas
Dr Christopher Snowden
Cardiorespiratory Reserve Is Associated with 90 Day Mortality Following Liver Transplantation.2011
Rehan Saif
Stuart Robinson
Professor Derek Manas
Steven White
Laparoscopic Pringle's manoeuvre for liver resection - how I do it2011
Dr Imran Patanwala
Professor Derek Manas
Dr Mark Hudson
Professor Helen Reeves
NAFLD and the changing face of hepatocellular cancerER (HCC)2011
Dr Imran Patanwala
Dr John Rose
Bryon Jaques
Professor Derek Manas
Dr Mark Hudson
et al.
NAFLD related HCC is rising dramatically in the North of England2011
Professor Stuart McPherson
Professor Derek Manas
Dr Mark Hudson
Dr Stephen Stewart
Outcomes of liver transplantation for alcoholic liver disease are good, but cancer is a frequent cause of death2011
Stuart Robinson
Professor Jelena Mann
Professor Alastair Burt
Professor Derek Manas
Professor Derek Mann
et al.
Pathogenesis of chemotherapy associated liver injury prior to major hepatic resection2011
Dr Colin Wilson
Dr Nicholas Torpey
Bryon Jaques
Dr Lisa Turnbull
David Talbot
et al.
Successful Simultaneous Liver-Kidney Transplant in an Adult With Atypical Hemolytic Uremic Syndrome Associated With a Mutation in Complement Factor H2011
Dr Alison Brown
Professor Tim Goodship
Professor Neil Sheerin
Professor Derek Manas
Successful Treatment of De Novo Posttransplant Thrombotic Microangiopathy With Eculizumab2011
Stuart Robinson
Professor Derek Manas
Professor Derek Mann
Steven White
Systemic chemotherapy and its implications for resection of colorectal liver metastasis2011
Dhakshina Vijayanand
Ajay Gupta
Nikil Vasdev
Professor Naeem Soomro
David Rix
et al.
A prospective randomised paired trial of sirolimus versus tacrolimus as primary immunosuppression following non heart beating donor kidney transplantation after anti-IL2 monoclonal antibody induction2010
Professor Derek Manas
Assessment of reproducibility of creatinine measurement and MELD scoring in four liver transplant units in the UK2010
Mohamed Noormohamed
Professor Matthew Wright
Dr David Cowie
Susan Stamp
Professor Derek Mann
et al.
Extracorporeal membranous oxygenation in a porcine non-heart beating liver model - a valuable tool for improving hepatocyte viability2010
Mohamed Noormohamed
Dr David Cowie
Susan Stamp
Professor Derek Manas
Professor Matthew Wright
et al.
Hepatoycte isolation a surrogate for liver transplant- extracorporeal membranous oxygenation a valuable tool for improved hepatocyte viability in a non-heart beating porcine model2010
Dr Petros Perros
Professor Derek Manas
Survival of Neuroendocrine Tumor Patients in Newcastle NHS Foundation Trust2010
Liam Cornell
Dr Joanne Martin
Febrina Budhisetiawan
Professor Herbie Newell
Professor Derek Manas
et al.
Synthetic lethality in liver cancer cell lines treated with inhibitors of DNA double strand break repair2010
Dr Joseph Gray
Dr Dipanker Chattopadhyay
Dr Gary Beale
Dr Gillian Patman
Dr Luca Miele
et al.
A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease2009
Professor Fiona Oakley
Dr Martha Watson
Professor Derek Manas
Professor Derek Mann
Angiotensin II Activates IκB Kinase Phosphorylation of RelA at Ser536 to Promote Myofibroblast Survival and Liver Fibrosis2009
Dhakshina Vijayanand
Professor Derek Manas
Professor Naeem Soomro
David Talbot
David Rix
et al.
Laparoscopic donor nephrectomy: Effects of large volume intra-operative fluid administration2009
Dr Catherine Arden
Dr Laura Hampson
Professor James Shaw
Dr Ali Aldibbiat
Dr Graham Holliman
et al.
A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic β-cells2008
Dr Gary Beale
Dr Dipanker Chattopadhyay
Dr Joseph Gray
Dr Stephen Stewart
Dr Mark Hudson
et al.
AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease2008
John Asher
Professor Derek Manas
Immunosuppressive T cell antibodies for liver transplant recipients2008
Dr Martha Watson
Dr Karen Wallace
Dr Roben Gieling
Professor Derek Manas
Professor Derek Mann
et al.
NF-κB is a critical regulator of the survival of rodent and human hepatic myofibroblasts2008
Dhakshina Vijayanand
Professor Colin Wilson
Dr Brian Shenton
Susan Stamp
Dr Katrina Wood
et al.
A comparison of C4d staining in renal allograft biopsies from heart beating and non heart beating donors2007
Dr Colin Wilson
Dr Nicholas Torpey
Professor Derek Manas
ABO incompatible liver transplantation: a case of immediate need2007
Professor Derek Manas
Accuracy of staging as a predictor for recurrence after liver transplantation for hepatocellular carcinoma2007
Professor Colin Wilson
John Asher
Dhakshina Vijayanand
Hugh Wyrley-Birch
Susan Stamp
et al.
Comparison of HTK and hypertonic citrate to intraarterial cooling in human non-heart-beating kidney donors2007
Leo Smith
Bryon Jaques
Dr Kaushik Agarwal
Dr Mark Hudson
David Talbot
et al.
Do laparoscopy and intraoperative ultrasound have a role in the assessment of patients with end-stage liver disease and hepatocellular carcinoma for liver transplantation?2007
Dr Colin Wilson
David Rix
Professor Derek Manas
David Talbot
Donation after cardiac death kidneys with low severity pre-arrest acute renal failure2007
Aliu Sanni
Professor Colin Wilson
Hugh Wyrley-Birch
Dhakshina Vijayanand
Bryon Jaques
et al.
Donor risk factors for renal graft thrombosis2007
Dr Ali Aldibbiat
Dr Brian Shenton
Professor James Shaw
Dr Noel Carter
Professor Derek Manas
et al.
Hypothermic machine perfusion for preservation and viability assessment of porcine non-heart-beating-donor pancreas: Initial results2007
Dr Kaushik Agarwal
Professor Alastair Burt
David Talbot
Bryon Jaques
Professor Derek Manas
et al.
Late humoral rejection in a compliant ABO-compatible liver transplant recipient (vol 82, pg 988, 2006)2007
Professor Derek Manas
Dr Viney Wadehra
Professor Kofi Oppong
Linear endoscopic ultrasound (EUS) assessment and EUS-fine needle aspiration of hilar lesions2007
Steven White
Professor Derek Manas
Liver resection for colorectal liver metastasis2007
Dr Mark Hudson
Professor Derek Manas
Non-transplant surgery for dominant stricture in primary sclerosing cholangitis: Revisited2007
Dhakshina Vijayanand
Professor Derek Manas
David Talbot
Outcomes of damaged donor livers following liver transplantation2007
Bryon Jaques
Dr Nicholas Torpey
Professor Derek Manas
Pancreas graft salvage using pancreatico-duodenectomy with enteric drainage2007
Professor Derek Manas
Richard Charnley
Professor Kofi Oppong
Preoperative staging of pancreaticobiliary tumours: The role of endoscopic ultrasound (EUS) with EUS fine needle aspiration when computed tomography is inconclusive2007
John Asher
Professor Colin Wilson
Muhammed Gok
David Rix
Professor Naeem Soomro
et al.
Significance of the duration of delayed graft function in DCD kidney transplantation2007
Dr Dipanker Chattopadhyay
Professor Derek Manas
Professor Helen Reeves
The development of targeted therapies for hepatocellular cancer2007
Dr Ali Aldibbiat
Professor Anne Dickinson
Professor Derek Manas
Professor James Shaw
[abstract] Confirmation of maintained sterility, viability and function in clinical-grade human islets following transport from an approved geographically-distance isolation facility2006
John Asher
Colin Wilson
Aliu Sanni
Hugh Wyrley-Birch
David Rix
et al.
Agonal period in potential non-heart-beating donors2006
Professor Derek Manas
Dr Nicholas Thompson
Anthropometric markers and outcome from liver transplant2006
Dr Ee Lim
Denise Carr
Professor Derek Manas
Dr Richard Quinton
Dr Robert James
et al.
Carcinoid tumour: spontaneous regression following pregnancy2006
Professor Kofi Oppong
Dr David Richardson
Bryon Jaques
Professor Derek Manas
Richard Charnley
et al.
CT and endoscopic ultrasound in the diagnosis and staging of pancreatic and periampullary malignancy2006
Abouzar Sohrabi
Aliu Sanni
Hugh Wyrley-Birch
David Rix
Professor Derek Manas
et al.
Diabetic donors as a source of non-heart-beating renal transplants2006
Hugh Wyrley-Birch
Dhakshina Vijayanand
Aliu Sanni
Professor Derek Manas
David Rix
et al.
Dual renal transplantation for kidneys from marginal non-heart-beating donors2006
Dr Graham Holliman
Dr Ali Aldibbiat
Dr Susan Campbell
Professor Derek Manas
Professor Majlinda Lako
et al.
Expression of the pluripotent stem cell marker OCT-4 in normal adult human pancreas2006
Rajiv Lochan Jayadeva
Dr Mark Bennett
Professor Derek Manas
Granular cell tumor as an unusual cause of obstruction at the hepatic hilum: Report of a case2006
Dr Kaushik Agarwal
Professor Derek Manas
Dr Mark Hudson
How good are we at minimising cardiovascular risk following orthotopic liver transplant?2006
Muhammed Gok
Dr Brian Shenton
Dr David Mantle
David Rix
Bryon Jaques
et al.
Ischemia-reperfusion injury in cadaveric nonheart beating, cadaveric heart beating and live donor renal transplants2006
Dr Caroline Wilson
Professor Derek Manas
Dr Mbithe Mutunga
Dr William Howell
Late antibody mediated rejection in liver transplantation - A case study, or proof of principle?2006
Dr Kaushik Agarwal
David Talbot
Bryon Jaques
Professor Derek Manas
Professor Alastair Burt
et al.
Late humoral rejection in a compliant ABO-compatible liver transplant recipient2006
Dr Kaushik Agarwal
Professor Derek Manas
Dr Mark Hudson
MELD, MELD-s and donor graft quality do not predict patient or graft survival post liver transplant.2006
Aliu Sanni
Professor Colin Wilson
Hugh Wyrley-Birch
Dhakshina Vijayanand
Muhammed Gok
et al.
Non-heart-beating kidney transplantation: 6-year outcomes2006
Aliu Sanni
John Asher
Dr Caroline Wilson
Hugh Wyrley-Birch
Dhakshina Vijayanand
et al.
Predisposing factors for biliary complications following liver transplantation2006
Dr Caroline Wilson
John Asher
Aliu Sanni
Hugh Wyrley-Birch
Dhakshina Vijayanand
et al.
Renal graft function after prolonged agonal time in non-heart-beating donors2006
Dr Caroline Wilson
Aliu Sanni
Hugh Wyrley-Birch
Dhakshina Vijayanand
David Rix
et al.
Renal transplants from category III non-heart-beating donors with evidence of pre-arrest acute renal failure2006
Professor Colin Wilson
David Rix
Professor Derek Manas
A meta-analysis of the prophylactic use of ureteric stents in renal transplantation2005
John Asher
Professor Colin Wilson
Muhammed Gok
Dr Brian Shenton
David Rix
et al.
A simple cardiovascular risk score can predict poor outcome in NHBD renal transplantation2005
Rakesh Rai
Emeritus Professor Paul Flecknell
Dr Claire Richardson
Professor Derek Manas
Creation of porcine liver tumor using human hepatoma cell lines: Experimental study2005
Professor Derek Manas
Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen: Results of a five-year, prospective, randomized study2005
Muhammed Gok
John Asher
Dr Brian Shenton
Professor Naeem Soomro
Bryon Jaques
et al.
Do recipients of kidneys from donors treated with streptokinase develop anti-streptokinase antibodies?2005
Ajay Gupta
Dr Brian Shenton
Susan Stamp
Bryon Jaques
Professor Derek Manas
et al.
Functional assessment of Epstein Barr virus specific cytotoxic T cells using MHC class I-PEPTIDE complexes2005
Dr Mark Hudson
Dr Christopher Snowden
Dr Ahmed Chishti
Professor Derek Manas
Dr Kaushik Agarwal
et al.
Liver transplantation in acute liver failure: Intracranial pressure monitoring optimizes patient selection and outcome2005
David Rix
Professor Derek Manas
Routine intraoperative stenting for renal transplant recipients2005
Dr Claire Richardson
Emeritus Professor Paul Flecknell
Dr Helen Robertson
Professor Alastair Burt
Professor Derek Manas
et al.
Study of apoptosis and heat shock protein (HSP) expression in hepatocytes following radiofrequency ablation (RFA)2005
Professor Kofi Oppong
Dr David Richardson
Dr Mark Egan
Professor Derek Manas
Bryon Jaques
et al.
The performance of linear EUS, endoscopist aspirate assessment, fluid cytology, and fluid tumour markers in the diagnosis of pancreatic cystic lesions2005
John Asher
Professor Colin Wilson
Muhammed Gok
Professor Naeem Soomro
David Rix
et al.
Variation in organ donation in northeastern England 1986 to 20032005
John Asher
Professor Colin Wilson
Muhammed Gok
Dr Brian Shenton
David Rix
et al.
Viability assessment allows use of uncontrolled and extended criteria kidneys from donors after cardiac death.2005
John Asher
Professor Colin Wilson
Muhammed Gok
Dr Brian Shenton
Basav Sen
et al.
Does donor cardiopulmonary resuscitation time affect outcome in uncontrolled non-heart-beating donor renal transplants?2004
John Asher
Professor Colin Wilson
Muhammed Gok
Professor Naeem Soomro
David Rix
et al.
Factors predicting duration of delayed graft function in non-heart-beating donor kidney transplantation2004
Muhammed Gok
John Asher
Dr Brian Shenton
David Rix
Professor Naeem Soomro
et al.
Graft function after kidney transplantation from non-heartbeating donors according to Maastricht category2004
Richard Charnley
Professor Derek Manas
Dr Mark Bennett
Seamus Kelly
Growth-promoting effect of progastrin in liver metastases from colorectal cancer2004
Richard Charnley
Bryon Jaques
Professor Derek Manas
Management and outcome of bile duct injuries complicating cholecystectomy2004
Richard Charnley
Bryon Jaques
Professor Derek Manas
Management of Hilar cholangiocarcinoma (Klatskin tumour): A single centre experience2004
Professor Kofi Oppong
Richard Charnley
Professor Derek Manas
Bryon Jaques
Dr David Richardson
et al.
Prospective audit of the introduction of EUS-FNA to a regional pancreatico-biliary cancer centre2004
Rakesh Rai
Dr John Rose
Professor Derek Manas
An unusual case of haemobilia2003
Muhammed Gok
Dr Brian Shenton
Dr David Mantle
Bryon Jaques
Professor Naeem Soomro
et al.
Creatinine clearance and viability biomarkers of machine perfused non-heart-beating donors: Is there a correlation?2003
Muhammed Gok
Dr Brian Shenton
Dr David Mantle
Professor Naeem Soomro
Bryon Jaques
et al.
Do tissue damage biomarkers used to assess machine-perfused NHBD kidneys predict long-term renal function post-transplant?2003
Muhammed Gok
Professor Naeem Soomro
Professor Derek Manas
David Talbot
En bloc pediatric into adult recipients: The Newcastle experience2003
Rakesh Rai
Professor Derek Manas
Factors predictive of 5-year survival after transarterial chemoembolization for inoperable hepatocellular carcinoma (Br J Surg 2003; 90 : 325-331)2003
Muhammed Gok
Dr Brian Shenton
Professor Naeem Soomro
Bryon Jaques
Professor Derek Manas
et al.
How to improve the quality of kidneys from non-heart-beating donors: A randomised controlled trial of thrombolysis in non-heart-beating donors2003
Rakesh Rai
Professor Derek Manas
Lesion progression with time and the effect of vascular occlusion following radiofrequency ablation of the liver2003
Dr John Rose
Professor Derek Manas
Potentially fatal haemobilia due to inappropriate use of an expanding biliary stent2003
Dr John Rose
Professor Derek Manas
Radiofrequency ablation of recurrent cholangiocarcinoma after orthotopic liver transplantation2003
Professor Derek Manas
Radiofrequency ablation of unresectable liver tumours2003
Rakesh Rai
David Talbot
Professor Derek Manas
The use of isosafe verifiable temperature control unit-for liver graft storage prior to orthotopic liver transplantation2003
Muhammed Gok
Dr Brian Shenton
Dr David Mantle
Professor Naeem Soomro
Bryon Jaques
et al.
Use of thrombolytic streptokinase as a preflush in the NHBD procurement2003
David Talbot
Professor Derek Manas
Dr Brian Shenton
[Meeting abstract] Comparison of panel reactive antibody methodologies2002
Rakesh Rai
David Talbot
Professor Derek Manas
Clinical benefit of monitoring cyclosporine C2 and C4 in long-term liver transplant recipients2002
Professor Derek Manas
Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen in stable kidney transplant recipients: A randomized, controlled study2002
Muhammed Gok
Dr Brian Shenton
Professor Naeem Soomro
Professor Derek Manas
David Talbot
et al.
Long-term renal function after transplantation from non-heart-beating donor kidneys2002
Muhammed Gok
Dr Brian Shenton
Dr Helen Robertson
Professor Naeem Soomro
Bryon Jaques
et al.
Long-term renal function in kidneys from non-heart-beating donors: A single-center experience2002
Rakesh Rai
Professor Derek Manas
Percutaneous radiofrequency thermoablation as an alternative to surgery for treatment of liver tumour recurrence after hepatectomy2002
Dr Malcolm Coulthard
Emeritus Professor Paul Flecknell
Hannah Orr
Professor Derek Manas
Dr Marie O'Donnell
et al.
Renal scaring caused by vesicoureteric reflux and urinary infection: A study in pigs2002
Dr Birju Rana
Dr Chris Redfern
Professor Derek Manas
Professor Margaret Bassendine
Retinoic acid receptor-selective ligands and hepatocellular carcinoma (HCC)2002
Muhammed Gok
Dr Brian Shenton
Professor Derek Manas
Professor Naeem Soomro
David Talbot
et al.
Creatinine clearance in recipients of kidneys from non-heartbeating donors2001
Dr Brian Shenton
Professor Derek Manas
Professor John Dark
David Talbot
Alison Bell
et al.
Immune monitoring of anti-thymocyte globulin (ATG) treatment in transplant patients2001
Dr Nicholas Hoenich
Dr Christopher Snowden
Professor Derek Manas
Emeritus Professor John Kirby
David Talbot
et al.
Machine perfusion for kidneys: How to do it at minimal cost2001
Dr Stephen Stewart
Dr Mark Hudson
David Talbot
Professor Derek Manas
Professor Chris Day
et al.
Mycophenolate mofetil monotherapy in liver transplantation2001
Professor John Magee
Dr Mark Hudson
Professor Derek Manas
Professor Kate Gould
Dr Katherine Orr
et al.
Tuberculosis transmitted through transplantation2001
Emeritus Professor John Kirby
Professor Derek Manas
David Talbot
Assessment of non-heart-beating donor (NHBD) kidneys for viability on machine perfusion2000
David Talbot
Dr Christopher Snowden
Professor Derek Manas
Emeritus Professor John Kirby
Comparison of proteolytic enzymes and glutathione S-transferase levels in non-heart-beating donors' (NHBD) kidney perfusates2000
Basav Sen
Professor Derek Manas
Early results of a non-heartbeating donor (NHBD) programme with machine perfusion2000
Dr David Mantle
Dr Brian Shenton
Muhammed Gok
Professor Naeem Soomro
Professor Derek Manas
et al.
Machine perfusion and viability assessment of non-heart-beating donor kidneys: A single-centre result2000
Dr Christopher Snowden
Professor Derek Manas
Emeritus Professor John Kirby
David Talbot
Non-heart-beating kidney donors (multiple letters)2000
Professor Derek Manas
Professor Simi Ali
Emeritus Professor John Kirby
David Talbot
The impact of cytomegalovirus serology for 7-year graft survival in cadaveric kidney transplantation - The Newcastle experience2000
Vassillios Avlonitis
Professor Derek Manas
Gary Cavanagh
David Talbot
The relevance of donor T cell-directed immunoglobulin G in historic sera in the age of flow cytometry2000
Dr Christopher Snowden
Dr Paul Griffiths
Professor Derek Manas
Emeritus Professor John Kirby
The trouble with kidneys derived from the non heart-beating donor: A single center 10-year experience2000
David Talbot
David Rix
Professor Derek Manas
"En bloc" paediatric renal donors into adult recipients - the Newcastle technique1999
Professor Derek Manas
Anomalous pancreaticobiliary junction without congenital choledochal cyst1999
Professor Derek Manas
Richard Charnley
During liver regeneration following right portal vein embolization the growth rate of liver metastases is more rapid than that of the liver parenchyma1999
Professor Derek Manas
Michael Thick
David Talbot
Early regrafting after primary liver transplantation carries increased risk of death1999
Professor Derek Manas
David Talbot
Expansion of donor pool: lack of function predictors1999
Professor Derek Manas
Induced hypothermia in the management of cerebral oedema secondary to fulminant liver failure1999
Professor Derek Manas
Preliminary results of a randomised, controlled study investigating the withdrawal of neoral in stable renal transplant recipients receiving mycophenolate mofetil in addition to neoral and steroids1999
Dr Kaushik Agarwal
Professor Derek Manas
Dr Mark Hudson
Terbinafine and fulminant hepatic failure1999
Professor Helen Reeves
Professor Derek Manas
Professor Margaret Bassendine
Dr Mark Hudson
Emeritus Professor Oliver James
et al.
Intravenous bisphosphonate pre liver transplant prevents osteoporotic vertebral collapse1996