Publications by Professor Robert Hirt - ePrints

Browsing publications by Professor Robert Hirt.

Newcastle Authors	Title	Year
Charlotte Brown Karla Helena Bueno Professor Robert Hirt Dr Sergey Melnikov	A Conserved Ribosomal Protein Has Entirely Dissimilar Structures in Different Organisms	2024
Lenshina Mpeyako Adam Hart Dr Nick Bailey Professor Robert Hirt	Comparative genomics between Trichomonas tenax and Trichomonas vaginalis: CAZymes and candidate virulence factors	2024
Professor Robert Hirt	ICAP 2024: anaerobic protozoology in focus, a partnership with parasitology societies in the South Pacific	2024
Dr Nick Bailey Professor Robert Hirt	Evolutionary conservation of Trichomonas-mycoplasma symbiosis across the host species barrier	2023
Omar Al-Jourani Dr Jenn Ross Dr Nick Bailey Dr Tiaan Heunis Joseph Manion et al.	Identification of D-arabinan-degrading enzymes in mycobacteria	2023
Dr Jacob Biboy Dr Joseph Gray Professor Waldemar Vollmer Professor Robert Hirt	NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli	2023
Dr Nick Bailey Professor Robert Hirt	Revisiting faecal metatranscriptomics analyses of macaques with idiopathic chronic diarrhoea with a focus on trichomonad parasites	2023
Dr Marco Salamina Dr Johan Panek Karla Helena Bueno Charlotte Brown Professor Robert Hirt et al.	Adaptation to genome decay in the structure of the smallest eukaryotic ribosome	2022
Dr Valentina Margarita Dr Nick Bailey Professor Robert Hirt	Effect of the Symbiosis with Mycoplasma hominis and Candidatus Mycoplasma girerdii on Trichomonas vaginalis Metronidazole Susceptibility	2022
Dr Kacper Sendra Andrew Watson Ekaterina Kozhevnikova Emeritus Professor T. Martin Embley FMedSci FRS Professor Robert Hirt et al.	Inhibition of mitosomal alternative oxidase causes lifecycle arrest of early-stage Trachipleistophora hominis meronts during intracellular infection of mammalian cells	2022
Dr Valentina Margarita Dr Nick Bailey Professor Robert Hirt	Two different species of Mycoplasma endosymbionts can influence Trichomonas vaginalis pathophysiology	2022
Tamara Salloum Salloum Professor Robert Hirt	Advances in Understanding Leishmania Pathobiology: What does RNA-Seq Tell Us?	2021
Dr Nick Bailey Professor Robert Hirt	Sporadic isolation of Tetratrichomonas species from the cattle urogenital tract	2021
Heli Monttinen Dr Cedric Bicep Dr Timothy Williams Professor Robert Hirt	The genomes of nucleocytoplasmic large DNA viruses: viral evolution writ large	2021
Will Lewis Dr Kacper Sendra Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Convergent evolution of hydrogenosomes from mitochondria by gene transfer and loss	2020
Tamara Salloum Salloum Professor Robert Hirt	Expanded genome-wide comparisons give novel insights into population structure and genetic heterogeneity of Leishmania tropica complex	2020
Dr Peter Major Dr Kacper Sendra Dr Paul Dean Dr Tom Williams Andrew Watson et al.	A new family of cell surface located purine transporters in Microsporidia and related fungal endoparasites	2019
Dr Ewen Sommerville Professor Robert Hirt	Characterization of the BspA and Pmp protein family of trichomonads	2019
Professor Robert Hirt	Mucosal microbial parasites/symbionts in health and disease: an integrative overview	2019
Dr Jacob Biboy Professor Waldemar Vollmer Professor Robert Hirt	The Protozoan Trichomonas vaginalis Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases	2018
Dr Paul Dean Dr Kacper Sendra Dr Tom Williams Andrew Watson Dr Peter Major et al.	Transporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites	2018
Dr Alina Goldberg Cavalleri Dr Paul Dean Dr Tom Williams Dr Sirintra Nakjang Dr Shaojun Long et al.	Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis	2017
Dr Tom Williams Dr Sirintra Nakjang Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	A Recent Whole-Genome Duplication Divides Populations of a Globally Distributed Microsporidian	2016
Dr Paul Dean Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Microsporidia: why make nucleotides if you can steal them?	2016
Dr Valentina Margarita Professor Robert Hirt	Symbiotic Association with Mycoplasma hominis Can Influence Growth Rate, ATP Production, Cytolysis and Inflammatory Response of Trichomonas vaginalis	2016
Professor Robert Hirt Dr Cecilia Alsmark Emeritus Professor T. Martin Embley FMedSci FRS	Lateral gene transfers and the origins of the eukaryote proteome: a view from microbial parasites	2015
Andrew Watson Dr Tom Williams Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Transcriptomic profiling of host-parasite interactions in the microsporidian Trachipleistophora hominis	2015
Professor Robert Hirt	Trichomonas vaginalis origins, molecular pathobiology and clinical considerations	2015
Dr Eva Heinz Dr Paul Dean Dr Alina Goldberg Cavalleri Dr Sirintra Nakjang Dr Alison Gregory et al.	Plasma Membrane-Located Purine Nucleotide Transport Proteins are Key Components for Host Exploitation by Microsporidian Intracellular Parasites	2014
Dr Paul Dean Dr Peter Major Dr Sirintra Nakjang Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS et al.	Transport proteins of parasitic protists and their role in nutrient salvage	2014
Professor Robert Hirt	What is the importance of zoonotic trichomonads for human health?	2014
Professor Robert Hirt	Trichomonas vaginalis virulence factors: an integrative overview	2013
Dr Cecilia Alsmark Dr Sirintra Nakjang Emeritus Professor T. Martin Embley FMedSci FRS Professor Robert Hirt	Patterns of prokaryotic lateral gene transfers affecting parasitic microbial eukaryotes	2013
Dr Sirintra Nakjang Dr Tom Williams Dr Eva Heinz Andrew Watson Dr Peter Foster et al.	Reduction and Expansion in Microsporidian Genome Evolution: New Insights from Comparative Genomics	2013
Dr Sirintra Nakjang Dr Didier Ndeh Professor Anil Wipat Dr David Bolam Professor Robert Hirt et al.	A Novel Extracellular Metallopeptidase Domain Shared by Animal Host-Associated Mutualistic and Pathogenic Microbes	2012
Matt Collison Professor Robert Hirt Professor Anil Wipat Dr Sirintra Nakjang	Data mining the human gut microbiota for therapeutic targets	2012
Dr Keith Flanagan Dr Sirintra Nakjang Dr Jennifer Hallinan Professor Colin Harwood Professor Robert Hirt et al.	Microbase2.0: a generic framework for computationally intensive bioinformatics workflows in the cloud	2012
Dr Eva Heinz Dr Tom Williams Dr Sirintra Nakjang Dr Christophe Noel Dr Daniel Swan et al.	The Genome of the Obligate Intracellular ParasiteTrachipleistophora hominis: New Insights into Microsporidian Genome Dynamics and Reductive Evolution	2012
Professor Robert Hirt Dr Sirintra Nakjang	Trichomonas vaginalis Pathobiology: New Insights from the Genome Sequence	2011
Dr Sirintra Nakjang Professor Robert Hirt Professor Anil Wipat	Automatic extraction of microorganisms and their habitats from free text using text mining workflows	2011
Professor Robert Hirt	Trichomonas vaginalis genome	2010
Dr Christophe Noel Professor Robert Hirt	Trichomonas vaginalis vast BspA-like gene family: evidence for functional diversity from structural organisation and transcriptomics	2010
Professor Robert Hirt	A metazoan/plant-like capping enzyme and cap modified nucleotides in the unicellular eukaryote Trichomonas vaginalis	2010
Dr Karin Hjort Dr Alina Goldberg Cavalleri Anastasios Tsaousis Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS et al.	Diversity and reductive evolution of mitochondria among microbial eukaryotes	2010
Dr Cecilia Alsmark Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Horizontal gene transfer in eukaryotic parasites: a case study of Entamoeba histolytica and Trichomonas vaginalis	2009
Anastasios Tsaousis Dr Alina Goldberg Cavalleri Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi	2008
Dr Alina Goldberg Cavalleri Anastasios Tsaousis Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Localization and functionality of microsporidian iron-sulphur cluster assembly proteins	2008
Dr Simon Harris Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Reductive Evolution of the Mitochondrial Processing Peptidases of the Unicellular Parasites Trichomonas vaginalis and Giardia intestinalis	2008
Christopher Cox Professor Robert Hirt Dr Simon Harris Emeritus Professor T. Martin Embley FMedSci FRS	The archaebacterial origin of eukaryotes	2008
Professor Robert Hirt Dr Christophe Noel	Trichomonas vaginalis surface proteins: a view from the genome	2007
Professor Robert Hirt	A genomic survey of the fish parasite Spironucleus salmonicida indicates genomic plasticity among diplomonads and significant lateral gene transfer in eukaryote genome evolution	2007
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Golgi-associated genes in the oxymonad Monocercomonoides sp suggest the presence of a cryptic organelle.	2007
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Of clades and clans: terms for phylogenetic relationships in unrooted trees	2007
Dr Christophe Noel Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Structure and Content of the Entamoeba histolytica Genome	2007
Dr Christophe Noel Professor Robert Hirt	Dramatic reorganisation of Trichomonas endomembranes during amoebal transformation: A possible role for G-proteins	2006
Professor Robert Hirt	Evolution of four gene families with patchy phylogenetic distributions: Influx of genes into protist genomes	2006
Professor Robert Hirt	Identification of a very large Rab GTPase family in the parasitic protozoan Trichomonas vaginalis	2005
Dr Cecilia Alsmark Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	The genome of the protist parasite Entamoeba histolytica	2005
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I	2004
Professor Robert Hirt	An overview on eukaryote origins and evolution: the beauty of the cell and the fabulous gene phylogenies	2004
Professor Robert Hirt	Organelles, Genomes and Eukaryote Phylogeny: An Evolutionary Synthesis in the Age of Genomics	2004
Professor Robert Hirt	RACE and RAGE cloning in parasitic microbial eukaryotes	2004
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS Dr Scott Muller	The amitochondriate eukaryote Trichomonas vaginalis contains a divergent thioredoxin-linked peroxiredoxin antioxidant system	2004
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Biochemical and genetic evidence for a family of heterotrimeric G-proteins in Trichomonas vaginalis	2003
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Horizontal gene transfer and the evolution of parasitic protozoa	2003
Professor Robert Hirt	Molecular evolution of the vertebrate blood coagulation network	2003
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	A mitochondrial remnant in the microsporidian Trachipleistophora hominis	2002
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	A novel potential surface protein in Trichomonas vaginalis contains a leucine-rich repeat shared by micro-organisms from all three domains of life	2002
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	A novel potential surface protein in Trichomonas vaginalis contains a leucine-rich repeat shared by micro-organisms from all three domains of life	2002
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	The diversity and evolution of thioredoxin reductase: new perspectives	2002
Professor Robert Hirt Dr Katalin Kovacs Emeritus Professor T. Martin Embley FMedSci FRS	The ribulose-1,5-bisphosphate carboxylase/oxygenase gene cluster of Methylococcus capsulatus (Bath)	2002
Professor Robert Hirt	Liddle's syndrome: a novel mouse Nedd4 isoform regulates the activity of the epithelial Na⁺ channel	2001
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	A single eubacterial origin of eukaryotic pyruvate: ferredoxin oxidoreductase genes: implications for the evolution of anaerobic eukaryotes	1999
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Microsporidia are related to Fungi: evidence from the largest subunit of RNA polymerase II and other proteins	1999
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Microsporidia are related to Fungi: Evidence from the largest subunit of RNA polymerase II and other proteins	1999
Emeritus Professor T. Martin Embley FMedSci FRS Professor Robert Hirt	Early branching eukaryotes?	1998
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Molecular and cellular evolution of ciliates: a phylogenetic perspective	1998
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Molecular phylogeny of Trichomonads and Naegleria: implication for the relative timing of the mitochondrion endosymbiosis	1998
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	A mitochondrial Hsp70 orthologue in Vairimorpha necatrix: molecular evidence that microsporidia once contained mitochondria	1997
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	A mitochondrial-like targeting signal on the hydrogenosomal malic enzyme from the anaerobic fungus Neocallimastix frontalis: support for the hypothesis that hydrogenosomes are modified mitochondria	1997
Professor Robert Hirt	Assessment of cell polarity	1996
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Molecular data suggest an early acquisition of the mitochondrion endosymbiont	1996
Emeritus Professor T. Martin Embley FMedSci FRS Professor Robert Hirt	Multiple origins of anaerobic ciliates with hydrogenosomes within the radiation of aerobic ciliates	1995
Professor Robert Hirt Emeritus Professor T. Martin Embley FMedSci FRS	Phylogenetic relationships among karyorelictids and heterotrichs inferred from small subunit rRNA sequences: resolution at the base of the ciliate tree	1995
Professor Robert Hirt	The polymeric immunoglobulin receptor: signals for polarized expression	1995
Emeritus Professor T. Martin Embley FMedSci FRS Professor Robert Hirt	Biodiversity at the molecular level: the domains, kingdoms and phyla of life	1994
Professor Robert Hirt	Inducible protein expression using a glucocorticoid-sensitive vector	1994
Emeritus Professor T. Martin Embley FMedSci FRS Professor Robert Hirt	Some rumen ciliates have endosymbiotic methanogens	1994
Professor Robert Hirt	Transcytosis of the polymeric Ig receptor requires phosphorylation of serine 664 in the absence but not the presence of dimeric IgA	1993
Professor Robert Hirt	Highly inducible synthesis of heterologous proteins in epithelial cells carrying a glucocorticoid-responsive vector	1992
Professor Robert Hirt	Role of transepithelial transport in triggering a mucosal immune response and in delivery of mucosal antibodies into secretions	1992
Professor Robert Hirt	Production and use of monoclonal IgA antibodies complexed with recombinant secretory component for passive mucosal protection	1991