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Browsing publications by Professor Lyle Armstrong.

Newcastle AuthorsTitleYearFull text
Marina Moya-Molina
Emily Flood
Dr Jonathan Coxhead
Dr Graham Smith
Professor Lyle Armstrong
et al.
Deciphering the impact of PROM1 alternative splicing on human photoreceptor development and maturation2024
Dr Joseph Collin
Dr Agata Rozanska
Dr Veronika Boczonadi
Marina Moya Molina
Adrienne Unsworth
et al.
Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level2024
Ivo Djidrovski
Professor Lyle Armstrong
Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures2024
Professor Lyle Armstrong
Dr Gerrit Hilgen
Professor Majlinda Lako
Investigating light sensitivity in bipolar disorder (HELIOS-BD)2024
Dr Marzena Kurzawa-Akanbi
Nik Tzoumas
Professor David Steel
Professor Lyle Armstrong
Professor Majlinda Lako
et al.
Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity2024
Rob Atkinson
Dr Maria Georgiou
Dr Chunbo Yang
Marina Moya Molina
Dr Joseph Collin
et al.
PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects2024
Dr Rozaliya Tsikandelova
Eldo Galo
Edvinas Cerniauskas
Dr Dean Hallam
Dr Maria Georgiou
et al.
Retinal cells derived from patients with DRAM2-dependent CORD21 dystrophy exhibit key lysosomal enzyme deficiency and lysosomal content accumulation2024
Ivo Djidrovski
Dr Maria Georgiou
Elena Tasinato
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
Direct transcriptomic comparison of xenobiotic metabolism and toxicity pathway induction of airway epithelium models at an air–liquid interface generated from induced pluripotent stem cells and primary bronchial epithelial cells2023
Professor Lyle Armstrong
Professor Majlinda Lako
Editorial: Methods and advances in induced pluripotent stem cells—ophthalmology2023
Dr Valeria Chichagova
Dr Maria Georgiou
Madeleine Carter
Dr Gerrit Hilgen
Dr Joseph Collin
et al.
Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids2023
Dr Maria Georgiou
Dr Chunbo Yang
Rob Atkinson
Dr Adriana Buskin
Dr Joseph Collin
et al.
Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient iPSC-derived retinal pigment epithelium cells2022
Robert Jackson
Catherine Hatton
Dr Jarmila Spegarova
Dr Maria Georgiou
Dr Joseph Collin
et al.
Conjunctival epithelial cells resist productive SARS-CoV-2 infection2022
Dr Maria Georgiou
Alex Chaudhary
Dr Joseph Collin
Dr Rachel Queen
Dr Birthe Hilgen
et al.
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina2022
Dr Agata Rozanska
Rodrigo Cerna Chavez
Dr Rachel Queen
Dr Joseph Collin
Dr Darin Zerti
et al.
pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell differentiation2022
Dr Marzena Kurzawa-Akanbi
Dr Florence Burte
Dr Birthe Hilgen
Dr Rachel Queen
Dr Jonathan Coxhead
et al.
Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina2022
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Sanja Bojic
Nicky Moyse
et al.
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells2021
Professor Lyle Armstrong
Dr Joseph Collin
Dr Islam Mostafa
Dr Rachel Queen
Professor Francisco Figueiredo
et al.
In the eye of the storm: SARS-CoV-2 infection and replication at the ocular surface?2021
Dr Chunbo Yang
Dr Maria Georgiou
Rob Atkinson
Dr Joseph Collin
Professor Lyle Armstrong
et al.
Pre-mRNA Processing Factors and Retinitis Pigmentosa: RNA Splicing and Beyond2021
Ivo Djidrovski
Dr Maria Georgiou
Marina Moya-Molina
Dr Git Chung
Professor Majlinda Lako
et al.
SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells2021
Dr Darin Zerti
Dr Birthe Hilgen
Dr Joseph Collin
Professor Lyle Armstrong
Professor Evelyne Sernagor
et al.
Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Maria Georgiou
et al.
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface2020
Edvinas Cerniauskas
Dr Marzena Kurzawa-Akanbi
Dr Long Xie
Dr Dean Hallam
Marina Moya Molina
et al.
Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of AMD by restoring lysosomal function2020
Dr Valeria Chichagova
Dr Gerrit Hilgen
Dr Ali Ghareeb
Madeleine Carter
Professor Evelyne Sernagor
et al.
Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line‐ and method‐dependent2020
Dr Sanja Bojic
Professor Lyle Armstrong
Professor Majlinda Lako
Dr Roman Bauer
Professor Miodrag Stojkovic
et al.
Platform to study intracellular polystyrene nanoplastic pollution and clinical outcomes2020
Dr Maria Georgiou
Dr Valeria Chichagova
Dr Birthe Hilgen
Professor Evelyne Sernagor
Professor Lyle Armstrong
et al.
Room temperature shipment does not affect the biological activity of pluripotent stem cell-derived retinal organoids2020
Dr Joseph Collin
Dr Darin Zerti
Dr Rachel Queen
Dr Roman Bauer
Dr Jonathan Coxhead
et al.
CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones2019
Dr Valeria Chichagova
Dr Birthe Hilgen
Majed Felemban
Dr Maria Georgiou
Professor Lyle Armstrong
et al.
Differentiation of Retinal Organoids from Human Pluripotent Stem Cells2019
Rachel Wilson
Charlotte Candlish
Dr Ibrahim Ibrahim
Dr Alistair Leitch
Dr Tarek Mamdouh Abdelghany
et al.
Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes2019
Dr Mandeep Atwal
Rebecca Swan
Ka Lee
Dr David Lee
Professor Lyle Armstrong
et al.
Intercalating TOP2 poisons attenuate topoisomerase action at higher concentrations2019
Dr Sanja Bojic
Dr Joseph Collin
Dr Min Yu
Professor Lyle Armstrong
Professor Francisco Figueiredo
et al.
Differences in the activity of endogenous BMP signalling impact on the ability of induced pluripotent stem cells to differentiate to corneal epithelial like cells2018
Dr Adriana Buskin
Dr Lili Zhu
Dr Valeria Chichagova
Dr David Dolan
Dr Joseph Collin
et al.
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa2018
Dr iRINA Neganova
Lewis Cotts
Dr Andrew Banks
Katja Gassner
Professor Lyle Armstrong
et al.
EDG5 plays an important role in induction and maintenance of pluripotency2018
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Ethical and safety issues of stem cell-based therapy2018
Minjin Jeong
Professor Majlinda Lako
Professor Lyle Armstrong
Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells2018
Dr Dean Hallam
Dr Birthe Hilgen
Dr Lili Zhu
Dr Min Yu
Dr Sanja Bojic
et al.
Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency2018
Dr Dean Hallam
David Rawlings
David Steel
Professor Lyle Armstrong
Professor Majlinda Lako
et al.
In Reply to the Letter to the Editor from Hallam et al.: An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure2018
Dario Melguizo Sanchis
Dr Yaobo Xu
Dheraj Taheem
Dr Min Yu
Dr Katarzyna Tilgner
et al.
iPSC modelling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors2018
Dr Tomas Barta
Professor Majlinda Lako
Professor Lyle Armstrong
Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study2018
Dr Irina Neganova
Dr Valeria Chichagova
Professor Lyle Armstrong
Professor Majlinda Lako
A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs2017
Dr Dean Hallam
Dr Joseph Collin
Dr Sanja Bojic
Dr Valeria Chichagova
Dr Adriana Buskin
et al.
An iPSC patient specific model of CFH (Y402H) polymorphism displays characteristic features of AMD and indicates a beneficial role for UV light exposure2017
Ellie Meader
Dr Tomas Barta
Dario Melguizo Sanchis
Dr Katarzyna Tilgner
Professor Lyle Armstrong
et al.
Brief Report: Pluripotent Stem Cell-Derived Hematopoietic Progenitors Are Unable to Downregulate Key Epithelial-Mesenchymal Transition-Associated miRNAs2017
Dario Melguizo Sanchis
Dr Sujith Samarasinghe
Professor Lyle Armstrong
Professor Majlinda Lako
Concise review: Getting to the core of inherited bone marrow failures2017
Dr Valeria Chichagova
Dr Dean Hallam
Dr Joseph Collin
Dr Adriana Buskin
Dr Gabriele Saretzki
et al.
Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A>G mitochondrial DNA mutation2017
Dr Chunbo Yang
Dr Yaobo Xu
Dr Min Yu
Dr David Lee
Dr John O'Sullivan
et al.
Induced pluripotent stem cell modelling of HLHS underlines the contribution of dysfunctional NOTCH signalling to impaired cardiogenesis2017
Professor Majlinda Lako
Professor Lyle Armstrong
Multiplex High-Throughput Targeted Proteomic Assay to Identify Induced Pluripotent Stem Cells2017
Professor Majlinda Lako
Professor Lyle Armstrong
Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience2017
Professor Lyle Armstrong
Professor Majlinda Lako
Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion2017
Dr Joseph Collin
Dr Lili Zhu
Professor Lyle Armstrong
Dr Irina Neganova
Professor Majlinda Lako
et al.
A Novel role for miR-1305 in Regulation of Pluripotency-Differentiation Balance, Cell Cycle and Apoptosis in Human Pluripotent Stem Cells2016
Professor Majlinda Lako
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Aging of Stem and Progenitor Cells: Mechanisms, Impact on Therapeutic Potential, and Rejuvenation2016
Dr Tomas Barta
Dr Joseph Collin
Dr Irina Neganova
Professor Lyle Armstrong
Professor Majlinda Lako
et al.
Inhibition of miR-145 Enhances Reprogramming of Human Dermal Fibroblasts to Induced Pluripotent Stem Cells2016
Dr Irina Neganova
Dr Evgeniya Shmeleva
Dr Jennifer Munkley
Dr Valeria Chichagova
Dr George Anyfantis
et al.
JNK/SAPK signalling is essential for efficient reprogramming of human fibroblasts to induced pluripotent stem cells2016
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Primordial Germ Cells: Current Knowledge and Perspectives2016
Dr Lili Zhu
Dr Aurora Gomez Duran
Dr Gabriele Saretzki
Dr Katarzyna Tilgner
Dario Melguizo Sanchis
et al.
The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages2016
Dr Chunbo Yang
Professor Majlinda Lako
Professor Lyle Armstrong
Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem Cells2015
Dr Valeria Chichagova
Dr Irene Sanchez-Vera
Professor Lyle Armstrong
Professor David Steel
Professor Majlinda Lako
et al.
Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population2015
Dr Saba Habibollah
Dr Katarzyna Tilgner
Dr Joseph Collin
Dr Tomas Barta
Raf Hussain
et al.
An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes2014
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Professor Majlinda Lako
Concise Review: The Epigenetic Contribution to Stem Cell Ageing: Can We Rejuvenate Our Older Cells?2014
Professor Majlinda Lako
Professor Lyle Armstrong
Engraftment's Holy Grail: is one signal enough?2014
Dr Katarzyna Tilgner
Dr Irina Neganova
Sun Yung
Chatcha Singhapol
Dr Gabriele Saretzki
et al.
A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors2013
Dr Mohammad Moad
Dr Deepali Pal
Dr Anastasia Hepburn
Dr Stuart Williamson
Laura Wilson
et al.
A novel model of urinary tract differentiation, tissue regeneration, and disease: Reprogramming human prostate and bladder cells into induced pluripotent stem cells2013
Dr Katarzyna Tilgner
Dr Irina Neganova
Chatcha Singhapol
Dr Gabriele Saretzki
Jerome Evans
et al.
Brief Report: A Human Induced Pluripotent Stem Cell Model of Cernunnos Deficiency Reveals an Important Role for XLF in the Survival of the Primitive Hematopoietic Progenitors2013
Sun Yung
Dr Katarzyna Tilgner
Dr Maria Ledran
Dr Saba Habibollah
Dr Irina Neganova
et al.
Brief Report: Human Pluripotent Stem Cell Models of Fanconi Anemia Deficiency Reveal an Important Role for Fanconi Anemia Proteins in Cellular Reprogramming and Survival of Hematopoietic Progenitors2013
Dr Stuart Atkinson
Professor Majlinda Lako
Professor Lyle Armstrong
Potential for Pharmacological Manipulation of Human Embryonic Stem Cells2013
Stuart Atkinson
Dr Joseph Collin
Dr George Anyfantis
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
A Putative Role for the Immunoproteasome in the Maintenance of Pluripotency in Human Embryonic Stem Cells2012
Dr Yan Jiang
Dr Katarzyna Tilgner
Dr Gabriele Saretzki
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
Derivation and functional analysis of patient specific induced pluripotent stem cells (IPSCS) as an in vitro model of chronic granulomatous disease2012
Dr Yan Jiang
Dr Katarzyna Tilgner
Dr Gabriele Saretzki
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
Derivation and Functional Analysis of Patient Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease2012
Dr Yan Jiang
Dr Katarzyna Tilgner
Dr Gabriele Saretzki
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease2012
Professor Lyle Armstrong
Epigenetic Control of Embryonic Stem Cell Differentiation.2012
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Our Top 10 Developments in Stem Cell Biology over the Last 30 Years2012
Dr Irina Neganova
Dr Stuart Atkinson
Dr Joao Passos
Professor Thomas von Zglinicki
Professor Lyle Armstrong
et al.
An Important Role for CDK2 in G1 to S Checkpoint Activation and DNA Damage Response in Human Embryonic Stem Cells2011
Sun Yung
Dr Maria Ledran
Ian Dimmick
Dr Nicholas Slater
Iliana Paraskevopoulou
et al.
Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells2011
Dr George Anyfantis
Professor Lyle Armstrong
Professor Majlinda Lako
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage2011
Dr Katarzyna Tilgner
Dr Stuart Atkinson
Sun Yung
Anna Golebiewska
Professor Miodrag Stojkovic
et al.
Expression of GFP Under the Control of the RNA Helicase VASA Permits Fluorescence-Activated Cell Sorting Isolation of Human Primordial Germ Cells2010
Professor Lyle Armstrong
Dr Katarzyna Tilgner
Dr Gabriele Saretzki
Dr Stuart Atkinson
Professor Miodrag Stojkovic
et al.
Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells2010
Dr Katarzyna Tilgner
Dr Chunbo Yang
Dr Irina Neganova
Professor Lyle Armstrong
Professor Majlinda Lako
et al.
Human-Induced Pluripotent Stem Cell-Derived Models for the Study of Spinal Muscular Atrophy2010
Professor Majlinda Lako
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Induced Pluripotent Stem Cells : It Looks Simple but Can Looks Deceive?2010
Professor Lyle Armstrong
Launch of the New Stem Cells Portal2010
Dr Stuart Atkinson
Professor Lyle Armstrong
Professor Derek Mann
Professor Majlinda Lako
Opposing Putative Roles for Canonical and Noncanonical NF kappa B Signaling on the Survival, Proliferation, and Differentiation Potential of Human Embryonic Stem Cells2010
Dr Katarzyna Tilgner
Professor Lyle Armstrong
Professor Majlinda Lako
Positive effect of human ESC conditioned medium on somatic cell reprogramming2010
Dr Irina Neganova
Dr Stuart Atkinson
Dr George Anyfantis
Dr Owen Hughes
Professor Tom Strachan
et al.
A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A2009
Anna Golebiewska
Stuart Atkinson
Professor Majlinda Lako
Professor Lyle Armstrong
Epigenetic Landscaping During hESC Differentiation to Neural Cells2009
Professor Majlinda Lako
Dr Irina Neganova
Professor Lyle Armstrong
G(1) to S transition and pluripotency Two sides of the same coin?2009
Dr Chunbo Yang
Dr Rebecca Stewart
Dr George Anyfantis
Stuart Atkinson
Dr Gabriele Saretzki
et al.
A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation2008
Dr Sajjad Ahmad
Sai Kolli
Ian Dimmick
Professor Lyle Armstrong
Professor Francisco Figueiredo
et al.
A putative role for RHAMM/HMMR as a negative marker of stem cell-containing population of human limbal epithelial cells2008
Professor Toivo Maimets
Dr Irina Neganova
Professor Lyle Armstrong
Professor Majlinda Lako
Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells2008
Dr Gabriele Saretzki
Theresia Walter
Dr Joao Passos
Dr Rebecca Stewart
Dr Simon Hoare
et al.
Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells2008
Dr Maria Ledran
Professor Lyle Armstrong
Ian Dimmick
Dr Rebecca Lang
Sun Yung
et al.
Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches2008
Professor Lyle Armstrong
Epigenetic control of stem cells, reprogramming, germ cells2008
Stuart Atkinson
Dr Rebecca Stewart
Professor Majlinda Lako
Professor Lyle Armstrong
Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells2008
Stuart Atkinson
Professor Lyle Armstrong
Epigenetics in embryonic stem cells: Regulation of pluripotency and differentiation2008
Dr Katarzyna Tilgner
Stuart Atkinson
Anna Golebiewska
Professor Miodrag Stojkovic
Professor Majlinda Lako
et al.
Isolation of Primordial Germ Cells from Differentiating Human Embryonic Stem Cells2008
Professor Lyle Armstrong
Law should recognize value of interspecies embryos2008
Petra Stojkovic
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Non-invasive Imaging of Stem Cells by Scanning Ion Conductance Microscopy: Future Perspective2008
Dr Rebecca Stewart
Dr Chunbo Yang
Dr George Anyfantis
Dr Nicholas Hole
Professor Tom Strachan
et al.
Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells2008
Dr Sajjad Ahmad
Dr Rebecca Stewart
Sun Yung
Sai Kolli
Professor Lyle Armstrong
et al.
Differentiation of human embryonic stem cells into corneal epithelial-like cells by in vitro replication of the corneal epithelial stem cell niche2007
Petra Stojkovic
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Derivation of human embryonic stem cells from developing and arrested embryos2006
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer2006
Professor Lyle Armstrong
Professor Majlinda Lako
The future of human nuclear transfer?2006
Professor Lyle Armstrong
Dr Owen Hughes
Sun Yung
Dr Louise Hyslop
Dr Rebecca Stewart
et al.
The role of PI3K/AKT, MAPK/ERK and NFκβ signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis2006
Petra Stojkovic
Professor Majlinda Lako
Dr Rebecca Stewart
Professor Lyle Armstrong
Jerome Evans
et al.
An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells2005
Petra Stojkovic
Professor Majlinda Lako
Dr Rebecca Stewart
Professor Lyle Armstrong
Professor Mary Herbert
et al.
An Autogeneic Feeder Cell System That Efficiently Supports Growth of Undifferentiated Human Embryonic Stem Cells2005
Professor Miodrag Stojkovic
Petra Stojkovic
Vanessa Hall
Professor Lyle Armstrong
Professor Mary Herbert
et al.
Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes2005
Dr Louise Hyslop
Professor Miodrag Stojkovic
Professor Lyle Armstrong
Theresia Walter
Petra Stojkovic
et al.
Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages2005
Petra Stojkovic
Professor Majlinda Lako
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Human embryonic stem cells express markers of pluripotency and differentiate under long-term in vitro growth conditions2005
Dr Louise Hyslop
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Professor Majlinda Lako
Human embryonic stem cells: Biology and clinical implications2005
Petra Stojkovic
Professor Majlinda Lako
Professor Lyle Armstrong
Jerome Evans
Professor Miodrag Stojkovic
et al.
Human-serum matrix supports undifferentiated growth of human embryonic stem cells2005
Professor Lyle Armstrong
Dr Gabriele Saretzki
Dr Heiko Peters
Ilka Wappler
Dr Nicholas Hole
et al.
Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage2005
Dr Sajjad Ahmad
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Ian Dimmick
Dr Louise Hyslop
et al.
The identification and characterisation of human corneal epithelial progenitors on the basis of high aldehyde dehydrogenase activity2005
Professor Lyle Armstrong
Professor Majlinda Lako
Dr Nicholas Hole
A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation2004
Professor Lyle Armstrong
Professor Majlinda Lako
Dr Gabriele Saretzki
Dr Nicholas Hole
A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation2004
Professor Miodrag Stojkovic
Professor Majlinda Lako
Petra Stojkovic
Dr Rebecca Stewart
Professor Lyle Armstrong
et al.
Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture2004
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Ian Dimmick
Dr Sajjad Ahmad
Petra Stojkovic
et al.
Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity2004
Dr Susan Campbell
Professor Lyle Armstrong
Dr Nicholas Hole
Professor Majlinda Lako
Programmed cell death gene 4 (PDCD4): A novel gene upregulated during islet neogenesis and embryonic stem cell differentiation2004
Dr Gabriele Saretzki
Professor Lyle Armstrong
Alan Leake
Professor Majlinda Lako
Professor Thomas von Zglinicki
et al.
Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells2004
Professor Majlinda Lako
Professor Lyle Armstrong
Paul Cairns
Dr Simon Harris
Dr Nicholas Hole
et al.
Hair follicle dermal cells repopulate the mouse haematopoietic system2002
Professor Majlinda Lako
Emerita Professor Susan Lindsay
Paul Cairns
Professor Lyle Armstrong
Dr Nicholas Hole
et al.
Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: Role of Wnt3 in enhancing haematopoietic differentiation2001
Dr John Perry
Professor Lyle Armstrong
Professor Kate Gould
Evaluation of p-naphtholbenzein-beta-D-galactoside as a substrate for bacterial beta-galactosidase2000
Professor Lyle Armstrong
Professor Majlinda Lako
Paul Cairns
mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells2000