Dr Amy Miller Dr Jasmine Clarkson Emma Geijer Simpson Emeritus Professor Paul Flecknell Dr Matthew Leach et al. | Evaluating pain and analgesia effectiveness following routine castration in rabbits using behaviour and facial expressions | 2022 |
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Henri Bertrand Emeritus Professor Paul Flecknell
| A cervical mass in a laboratory rhesus macaque (Macaca mulatta): Suspicion of air sacculitis | 2021 |
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Henri Bertrand Professor Stuart Baker Emeritus Professor Paul Flecknell
| Influence of alphaxalone on motor somatosensory evoked potentials in a female rhesus macaque (Macaca mulatta) | 2021 |
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Dr Jasmine Clarkson Dr Matthew Leach Emeritus Professor Paul Flecknell Professor Candy Rowe
| Negative mood affects the expression of negative but not positive emotions in mice. | 2020 |
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Emeritus Professor Paul Flecknell
| Welfare Impact of Carbon Dioxide Euthanasia on Laboratory Mice and Rats: A Systematic Review | 2020 |
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Dr Matthew Leach Emeritus Professor Paul Flecknell Dr Claire Witham
| Opportunities for Refinement in Neuroscience: Indicators of Wellness and Post-operative Pain in Laboratory Macaques1 | 2019 |
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Dr Colline Poirier Caitlin Oliver Janire Castellano Bueno Emeritus Professor Paul Flecknell Professor Melissa Bateson et al. | Pacing behaviour in laboratory macaques is an unreliable indicator of acute stress | 2019 |
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Dr Jenny Lofgren Dr Amy Miller Carla Bradshaw Emeritus Professor Paul Flecknell Dr Johnny Roughan et al. | Analgesics promote welfare and sustain tumour growth in orthotopic 4T1 and B16 mouse cancer models | 2018 |
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Dr Jasmine Clarkson Emeritus Professor Paul Flecknell Dr Matthew Leach Professor Candy Rowe
| Handling method alters the hedonic value of reward in laboratory mice | 2018 |
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Henri Bertrand Emeritus Professor Paul Flecknell
| Reported analgesic and anaesthetic administration to non-human primates undergoing experimental surgical procedure: 2010-2015 | 2018 |
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Henri Bertrand Charlotte Sanders Emeritus Professor Paul Flecknell
| The use of desflurane for neurosurgical procedures in rhesus macaque (Macaca mulatta) | 2018 |
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Henri Bertrand Charlotte Sanders Jennifer Murray Emeritus Professor Paul Flecknell
| A combination of alfaxalone, medetomidine and midazolam for the chemical immobilization of Rhesus macaque (Macaca mulatta): Preliminary results | 2017 |
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Emeritus Professor Paul Flecknell Dr Aurelie Thomas
| Comparative Anesthesia and Analgesia of Laboratory Animals | 2017 |
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Henri Bertrand Svenja Springer Emeritus Professor Paul Flecknell
| Comparison of emergence times and quality between isoflurane and sevoflurane in rhesus macaque (Macaca mulatta) undergoing neurosurgical procedure | 2017 |
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Dr Aurelie Thomas Emeritus Professor Paul Flecknell
| Minimally invasive technique for intrathecal administration of morphine in rats: practicality and antinociceptive properties | 2017 |
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Henri Bertrand Emeritus Professor Paul Flecknell
| Preliminary assessment of midazolam, fentanyl and fluanisone combination for the sedation of rhesus macaques (Macaca mulatta) | 2017 |
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Emeritus Professor Paul Flecknell
| Translational pain assessment: Could natural animal models be the missing link? | 2017 |
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Henri Bertrand Dr Aurelie Thomas Yvette Ellen Robert Dorward Emeritus Professor Paul Flecknell et al. | A surgical approach in the treatment of preputial gland abscesses in mice | 2016 |
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Henri Bertrand Yvette Ellen Stevie O'Keefe Emeritus Professor Paul Flecknell
| Comparison of the effects of ketamine and fentanyl-midazolam-medetomidine for sedation of rhesus macaques (Macaca mulatta) | 2016 |
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Dr Aurelie Thomas Dr Amy Miller Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Efficacy of intrathecal morphine in a model of surgical pain in rats | 2016 |
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Emeritus Professor Paul Flecknell
| Enhancing collaboration in the UK animal welfare research community | 2016 |
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Yvette Ellen Emeritus Professor Paul Flecknell Dr Matthew Leach
| Evaluation of Using Behavioural Changes to Assess Post-Operative Pain in the Guinea Pig (Cavia porcellus) | 2016 |
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Emeritus Professor Paul Flecknell
| Hospice and palliative care | 2016 |
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Emeritus Professor Paul Flecknell
| Opportunities for improving animal welfare in rodent models of epilepsy and seizures | 2016 |
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Dr Helen Gray Henri Bertrand Claire Mindus Emeritus Professor Paul Flecknell Professor Candy Rowe et al. | Physiological, behavioral, and scientific impact of different fluid control protocols in the rhesus macaque (Macaca mulatta) | 2016 |
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Dr Amy Miller Ben Skalkoyannis Emeritus Professor Paul Flecknell Dr Matthew Leach
| Using the mouse grimace scale and behaviour to assess pain in CBA mice following vasectomy | 2016 |
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Emeritus Professor Paul Flecknell Dr Jenny Lofgren
| Chapter 24 - Preanesthesia, Anesthesia, Analgesia, and Euthanasia | 2015 |
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Dr Simon Hill Professor Simon Thomas Emeritus Professor Paul Flecknell Dr Aurelie Thomas Dr Christopher Morris et al. | Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes | 2015 |
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Aimen Amer Dr Phillip Probert Dr Michael Dunn Margaret Knight Dr Abigail Vallance et al. | Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation | 2015 |
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Dr Malcolm Coulthard Dr Clive Griffiths Dr Michael Drinnan Professor John Matthews Emeritus Professor Paul Flecknell et al. | Haemodialysing babies weighing <8 kg with the Newcastle infant dialysis and ultrafiltration system (Nidus): comparison with peritoneal and conventional haemodialysis | 2014 |
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Dr Johnny Roughan Claire Coulter Emeritus Professor Paul Flecknell Huw Thomas
| The Conditioned Place Preference Test for Assessing Welfare Consequences and Potential Refinements in a Mouse Bladder Cancer Model | 2014 |
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Emeritus Professor Paul Flecknell Dr Aurelie Thomas
| A comparison of medetomidine and its active enantiomer dexmedetomidine when administered with ketamine in mice | 2013 |
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Graciela Rocha Dr Johnny Roughan Dr Matthew Leach Emeritus Professor Paul Flecknell Professor Colin Ingram et al. | Antinociceptive Activities of Hyptis crenata Pohl | 2013 |
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Siân Wright-Williams Emeritus Professor Paul Flecknell Dr Johnny Roughan
| Comparative Effects of Vasectomy Surgery and Buprenorphine Treatment on Faecal Corticosterone Concentrations and Behaviour Assessed by Manual and Automated Analysis Methods in C57 and C3H Mice | 2013 |
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Dr Amy Miller Siân Wright-Williams Emeritus Professor Paul Flecknell Dr Johnny Roughan
| A comparison of abdominal and scrotal approach methods of vasectomy and the influence of analgesic treatment in laboratory mice | 2012 |
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Dr Aurelie Thomas Dr Matthew Leach Emeritus Professor Paul Flecknell
| An alternative method of endotracheal intubation of common marmosets (Callithrix jacchus). | 2012 |
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Dr Matthew Leach Kristel Klaus Dr Amy Miller Emeritus Professor Paul Flecknell
| Are we looking in the right place? - Implications for assessing pain | 2012 |
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Dr Aurelie Thomas Emeritus Professor Paul Flecknell Dr Huw Golledge
| Combining Nitrous Oxide with Carbon Dioxide decreases the time to loss of consciousness during euthanasia in mice — refinement of animal welfare? | 2012 |
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Dr Stephanie Keating Dr Aurelie Thomas Emeritus Professor Paul Flecknell Dr Matthew Leach
| Evaluation of EMLA Cream for Preventing Pain during Tattooing of Rabbits: Changes in Physiological, Behavioural and Facial Expression Responses | 2012 |
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Veronique Brieuc Emeritus Professor Paul Flecknell Dr Amy Miller Dr Matthew Leach
| Peut-on utilliser les expressions faciales pour étudier la douleur chez les rongeurs? (Can we use facial expressions to study pain in rodents?) | 2012 |
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Emeritus Professor Paul Flecknell
| Response to Westlund's commentary: 'Can conditioned reinforcers and variable-Ratio Schedules make food- and fluid control redundant?' | 2012 |
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Dr Matthew Leach Dr Amy Miller Emeritus Professor Paul Flecknell
| The Assessment of Post-Vasectomy Pain in Mice using Behaviour and the Mouse Grimace Scale | 2012 |
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Dr Amy Miller Emeritus Professor Paul Flecknell Dr Matthew Leach Dr Johnny Roughan
| A comparison of a manual and an automated behavioural analysis method for assessing post-operative pain in mice | 2011 |
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Susan Stamp Dr Kathryn White Dr Katrina Wood Dr Aurelie Thomas Annie Russell et al. | A novel perfusion fluid for DCD donor kidneys; better as a flush or a storage medium? | 2011 |
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Emeritus Professor Paul Flecknell Dr Matthew Leach Professor Melissa Bateson
| Affective state and quality of life in mice | 2011 |
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Dr Matthew Leach Claire Coulter Dr Claire Richardson Emeritus Professor Paul Flecknell
| Are We Looking in the Wrong Place? Implications for Behavioural-Based Pain Assessment in Rabbits (Oryctolagus cuniculi) and Beyond? | 2011 |
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Dr Chris Ray Susan Stamp Dr Kathryn White Dr Katrina Wood Dr Aurelie Thomas et al. | Large animal renal allotransplantation; a porcine recovery model to assess delayed graft function | 2011 |
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Emeritus Professor Paul Flecknell Dr Matthew Leach Dr Claire Richardson
| Reported analgesic administration to rabbits undergoing experimental surgical procedures | 2011 |
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Dr Huw Golledge Emeritus Professor Paul Flecknell
| The effect of behavioural state and cage environment on responses to euthanasia with isoflurane or carbon dioxide in BALB/c mice | 2011 |
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Dr Matthew Leach Dr Amy Miller Dr Johnny Roughan Emeritus Professor Paul Flecknell
| A preliminary investigation into the practicality of use and duration of action of slow-release preparations of morphine and hydromorphone in laboratory rats | 2010 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Anaesthesia with a combination of ketamine and medetomidine in the rabbit: effect of premedication with buprenorphine | 2010 |
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Steven White Professor James Shaw Emeritus Professor Paul Flecknell Professor Alastair Burt Professor Matthew Wright et al. | Chronic elevated systemic glucocorticoid results in widespread pancreatic-hepatic trans-differentiation in vivo | 2010 |
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Dr Karen Wallace Emeritus Professor Paul Flecknell Professor Alastair Burt Professor Matthew Wright
| Disrupted Pancreatic Exocrine Differentiation and Malabsorption in Response to Chronic Elevated Systemic Glucocorticoid | 2010 |
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Emeritus Professor Paul Flecknell
| Do mice have a pain face? | 2010 |
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Dr Matthew Leach Alison Forrester Emeritus Professor Paul Flecknell
| Influence of preferred foodstuffs on the antinociceptive effects of orally administered buprenorphine in laboratory rats | 2010 |
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Dr Amy Miller Dr Matthew Leach Emeritus Professor Paul Flecknell
| Mesure de la fiabilité et de la precision des expressions facials pour évaluer la douler chez la souris | 2010 |
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Emeritus Professor Paul Flecknell
| Refinement of the use of food and fluid control as motivational tools for macaques used in behavioural neuroscience research Report of a Working Group of the NC3Rs | 2010 |
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Dr Matthew Leach Emeritus Professor Paul Flecknell
| The use of propofol and sevoflurane for surgical anaesthesia in New Zealand White rabbits | 2010 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Automated analysis of postoperative behaviour: assessment of HomeCageScan as a novel method to rapidly identify pain and analgesic effects in mice | 2009 |
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Dr Matthew Leach Dr Claire Richardson Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Behavioural effects of ovariohysterectomy and oral administration of meloxicam in laboratory housed rabbits | 2009 |
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Dr Matthew Leach Dr Claire Richardson Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Identifying potential behavioural indicators of pain in rabbits following ovariohysterectomy - Preliminary study | 2009 |
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Dr Amy Miller Dr Matthew Leach Emeritus Professor Paul Flecknell
| Influence of early neonatal experience on nociceptive responses and analgesic effects in rats | 2009 |
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Emeritus Professor Paul Flecknell
| Laboratory Animal Anaesthesia | 2009 |
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Claire Coulter Emeritus Professor Paul Flecknell Dr Claire Richardson
| Reported analgesic administration to rabbits, pigs, sheep, dogs and non-human primates undergoing experimental surgical procedures | 2009 |
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Emeritus Professor Paul Flecknell Dr Claire Richardson
| Reported analgesic and anaesthetic administration to rodents undergoing experimental surgical procedures | 2009 |
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Dr Amy Miller Dr Matthew Leach Emeritus Professor Paul Flecknell
| The analgesic effects of oral paracetamol in two strains of mice undergoing vasectomy | 2009 |
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Graciela Rocha Dr Johnny Roughan Dr Matthew Leach Emeritus Professor Paul Flecknell Professor Colin Ingram et al. | Traditional use, chemical analysis and antinociceptive effects of Hyptis crenato Pohl | 2009 |
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Emeritus Professor Paul Flecknell
| Analgesia from a veterinary perspective | 2008 |
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Emeritus Professor Paul Flecknell Jon Gledhill Dr Claire Richardson
| Assessing animal health and welfare and recognising pain and distress | 2007 |
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Dr Claire Richardson Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Effects of vasectomy surgery and meloxicam treatment on faecal corticosterone levels and behaviour in two strains of laboratory mouse | 2007 |
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Dr Claire Richardson Lee Niel Dr Matthew Leach Emeritus Professor Paul Flecknell
| Evaluation of the efficacy of a novel electronic pain assessment device, the Pain Gauge®, for measuring postoperative pain in rats | 2007 |
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Emeritus Professor Paul Flecknell Dr Claire Richardson
| Laboratory Animals | 2007 |
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Emeritus Professor Paul Flecknell
| Assessing the welfare of genetically altered mice | 2006 |
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Dr Huw Golledge Dr Matthew Leach Emeritus Professor Paul Flecknell
| Newcastle Consensus Meeting on Carbon Dioxide Euthanasia of Laboratory Animals | 2006 |
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Dr Claire Richardson Emeritus Professor Paul Flecknell
| Routine neutering of rabbits and rodents | 2006 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Training in behaviour-based post-operative pain scoring in rats - An evaluation based on improved recognition of analgesic requirements | 2006 |
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Dr Claire Richardson Emeritus Professor Paul Flecknell
| Anaesthesia and post-operative analgesia following experimental surgery in laboratory rodents: Are we making progress? | 2005 |
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Hannah Orr Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Assessment of ketamine and medetomidine anaesthesia in the domestic rabbit | 2005 |
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Rakesh Rai Emeritus Professor Paul Flecknell Dr Claire Richardson Professor Derek Manas
| Creation of porcine liver tumor using human hepatoma cell lines: Experimental study | 2005 |
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Emeritus Professor Paul Flecknell
| Partnerships for progress | 2005 |
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Dr Claire Richardson Emeritus Professor Paul Flecknell Dr Helen Robertson Professor Alastair Burt Professor Derek Manas et al. | Study of apoptosis and heat shock protein (HSP) expression in hepatocytes following radiofrequency ablation (RFA) | 2005 |
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Dr Nilofer Sabrine Dr Johnny Roughan Emeritus Professor Paul Flecknell
| [abstract] Assessment of post-operative pain in infants and neonates | 2004 |
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Emeritus Professor Paul Flecknell
| Assessing and managing pain and distress for ethics committees | 2004 |
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Emeritus Professor Paul Flecknell Dr Johnny Roughan
| Assessing pain in animals - Putting research into practice | 2004 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell Dr Barry Davies
| Behavioural assessment of the effects of tumour growth in rats and the influence of tne analgesics carprofen and meloxicam | 2004 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Behaviour-based assessment of the duration of laparotomy-induced abdominal pain and the analgesic effects of carprofen and buprenorphine in rats | 2004 |
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Luis Antunes Dr Huw Golledge Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Comparison of electroencephalogram activity and auditory evoked responses during isoflurane and halothane anaesthesia in the rat | 2003 |
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Luis Antunes Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Effects of different propofol infusion rates on EEG activity and AEP responses in rats | 2003 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Evaluation of a short duration behaviour-based post-operative pain scoring system in rats | 2003 |
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Luis Antunes Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Excitatory effects of fentanyl upon the rat electroencephalogram and auditory-evoked potential responses during anaesthesia | 2003 |
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Professor Simi Ali Emeritus Professor John Kirby Emeritus Professor Paul Flecknell Professor John Dark
| Improvements in lung compliance after pulmonary transplantation: Correlation with interleukin 8 expression | 2003 |
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Dr Doug Aitchison Hannah Orr Emeritus Professor Paul Flecknell Emeritus Professor John Kirby Professor John Dark et al. | Nitric oxide during perfusion improves posttransplantation function of non-heart-beating donor lungs | 2003 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Pain assessment and control in laboratory animals | 2003 |
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Emeritus Professor Paul Flecknell Professor John Dark
| Pentoxifylline is as effective as leukocyte depletion for modulating pulmonary reperfusion injury | 2003 |
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Hannah Orr Dr Johnny Roughan Luis Antunes Emeritus Professor Paul Flecknell
| Anaesthesia with ketamine/medetomidine in the rabbit: influence of route of administration and the effect of combination with butorphanol | 2002 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Buprenorphine: a reappraisal of its antinociceptive effects and therapeutic use in alleviating post-operative pain in animals | 2002 |
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Emeritus Professor Paul Flecknell Professor Jonathan Rees
| Production of acute and chronic itch with histamine and contact sensitizers in the mouse and guinea pig | 2002 |
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Dr Malcolm Coulthard Emeritus Professor Paul Flecknell Hannah Orr Professor Derek Manas Dr Marie O'Donnell et al. | Renal scaring caused by vesicoureteric reflux and urinary infection: A study in pigs | 2002 |
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Emeritus Professor Paul Flecknell
| Replacement, reduction and refinement | 2002 |
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Emeritus Professor Paul Flecknell
| Replacement, reduction and refinement | 2002 |
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Diana Levett Emeritus Professor Paul Flecknell Professor David Neal Kilian Mellon Dr Barry Davies et al. | Transfection of S100A4 produces metastatic variants of an orthotopic model of bladder cancer | 2002 |
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Emeritus Professor Paul Flecknell
| Analgesia of small mammals | 2001 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Behavioural effects of laparotomy and analgesic effects of ketoprofen and carprofen in rats | 2001 |
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Dr Doug Aitchison Hannah Orr Emeritus Professor Paul Flecknell Emeritus Professor John Kirby Professor John Dark et al. | Functional assessment of non-heart-beating donor lungs: Prediction of post-transplant function | 2001 |
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Dr Johnny Roughan Luis Antunes Hannah Orr Emeritus Professor Paul Flecknell
| Induction of anaesthesia with desflurane and isoflurane in the rabbit | 2001 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Effects of repeated anaesthesia with ketamine/medetomidine and of pre-anaesthetic administration of buprenorphine in rats | 2000 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Effects of surgery and analgesic administration on spontaneous behaviour in singly housed rats | 2000 |
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Emeritus Professor Paul Flecknell
| Pain Management in Animals | 2000 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| Sufentanil and medetomidine anaesthesia in the rat and its reversal with atipamezole and butorphanol | 2000 |
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Dr Gavin Clowry Emeritus Professor Paul Flecknell
| The successful use of fentanyl/fluanisone ('Hypnorm') as an anaesthetic for intracranial surgery in neonatal rats | 2000 |
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Emeritus Professor Paul Flecknell
| A comparison of pre- and post-surgical administration of bupivacaine or buprenorphine following laparotomy in the rat | 1999 |
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Stephen Clark Dr Johnny Roughan Emeritus Professor Paul Flecknell Professor John Dark
| A new porcine model of reperfusion injury after lung transplantation | 1999 |
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Emeritus Professor Paul Flecknell Hannah Orr Dr Johnny Roughan Robert Stewart
| Comparison of the effects of oral or subcutaneous carprofen or ketoprofen in rats undergoing laparotomy. | 1999 |
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Emeritus Professor Paul Flecknell Dr Johnny Roughan
| Induction of anaesthesia with sevoflurane and isoflurane in the rabbit | 1999 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell Professor John Dark
| Modulation of reperfusion injury after single lung transplantation by pentoxifylline, inositol polyanions, and SIN-1 | 1999 |
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Dr Johnny Roughan Emeritus Professor Paul Flecknell
| The influence of pre-anaesthetic administration of buprenorphine on the anaesthetic effects of ketamine/medetomidine and pentobarbitone in rats and the consequences of repeated anaesthesia | 1999 |
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Emeritus Professor Paul Flecknell Dr Johnny Roughan Robert Stewart
| Use of oral buprenorphine ('buprenorphine jello') for postoperative analgesia in rats - A clinical trial | 1999 |
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