Publications by Professor David Elliott - ePrints

Browsing publications by Professor David Elliott.

Newcastle Authors	Title	Year
Chile Siachisumo Dr Sara Luzzi Saad Aldalaqan Dr Gerald Hysenaj Caroline Dalgliesh et al.	An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression	2024
Dr Ingrid Ehrmann Professor David Elliott	Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development	2024
Rob Atkinson Dr Maria Georgiou Dr Chunbo Yang Marina Moya Molina Dr Joseph Collin et al.	PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects	2024
Dr Kirsty Hodgson Maggie Orozco Moreno Emily Archer Goode Dr Rebecca Garnham Karen Livermore et al.	Sialic acid blockade inhibits the metastatic spread of prostate cancer to bone	2024
Maggie Orozco Moreno Dr Kirsty Hodgson Amirah Nabilah Meera Murali Jess Peng et al.	Sialylation Inhibition Can Partially Revert Acquired Resistance to Enzalutamide in Prostate Cancer Cells	2024
Rebecca Garnham Dr Daniel Geh Ryan Nelson Erik Ramon Gil Laura Wilson et al.	ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer	2024
Caroline Dalgliesh Professor David Elliott	Clustered variants in the 5′ coding region of TRA2B cause a distinctive neurodevelopmental syndrome	2023
Rahul Advani Dr Sara Luzzi Dr Emma Scott Caroline Dalgliesh Dr Jennifer Munkley et al.	Epithelial specific splicing regulator proteins as emerging oncogenes in aggressive prostate cancer	2023
Rebecca Garnham Dr Daniel Geh Ryan Nelson Erik Ramon Gil Laura Wilson et al.	ST3Gal1 synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer	2023
Dr Kirsty Hodgson Maggie Orozco Moreno Dr Emma Scott Rebecca Garnham Karen Livermore et al.	The role of GCNT1 mediated O-glycosylation in aggressive prostate cancer	2023
Dr Emma Scott Dr Kirsty Hodgson Kat Cheung Edward Yo Laura Wilson et al.	Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth	2023
Chile Siachisumo Professor David Elliott	YBX1-interacting small RNAs and RUNX2 can be blocked in primary bone cancer using CADD522	2023
Hannah Smith Francesco Kumara Mastrorosa Dr Giles Holt Dr Brendan Houston Dr Bilal Alobaidi et al.	A de novo paradigm for male infertility	2022
Saad Aldalaqan Caroline Dalgliesh Dr Sara Luzzi Chile Siachisumo Dr Louise Reynard et al.	Cryptic splicing: common pathological mechanisms involved in male infertility and neuronal diseases	2022
Dr Emma Scott Rebecca Garnham Adam Duxfield Professor David Elliott Dr Jennifer Munkley et al.	Pro-Survival Factor EDEM3 Confers Therapy Resistance in Prostate Cancer	2022
Kayla Bastian Dr Emma Scott Professor David Elliott Dr Jennifer Munkley	Fut8 alpha-(1,6)-fucosyltransferase in cancer	2021
Dr Emma Scott Professor David Elliott Dr Jennifer Munkley	Tumour associated glycans: A route to boost immunotherapy?	2020
Alice Coomer Dr Fiona Black Professor Alastair Greystoke Dr Jennifer Munkley Professor David Elliott et al.	Alternative splicing in lung cancer	2019
Dr Ingrid Ehrmann Dr Katherine James Yilei Liu Dr Sushma Grellscheid Dr Jannetta Steyn et al.	An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning	2019
Dr Carla Jackson Dr Roman Bauer Dr Joseph Collin Dr Birthe Hilgen Dr Darin Zerti et al.	An integrated transcriptional analysis of the developing human retina	2019
Dr Jennifer Munkley SR Gokul Krishnan Gerald Hysenaj Dr Emma Scott Caroline Dalgliesh et al.	Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer	2019
Professor David Elliott Caroline Dalgliesh Gerald Hysenaj Dr Ingrid Ehrmann	RBMX family proteins connect the fields of nuclear RNA processing, disease and sex chromosome biology	2019
Dr Osagie Izuogu Dr Carla Mellough Dr Joseph Collin Dr Richard Gallon Francesco Kumara Mastrorosa et al.	Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular	2018
Dr Jennifer Munkley Karen Livermore Dr Ingrid Ehrmann Dr Katherine James Dr Prabhakar Rajan et al.	Androgen-dependent alternative mRNA isoform expression in prostate cancer cells	2018
Dr Adriana Buskin Dr Lili Zhu Dr Valeria Chichagova Dr David Dolan Dr Joseph Collin et al.	Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa	2018
Gerald Hysenaj Professor David Elliott	SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions	2018
Dr Marina Danilenko Caroline Dalgliesh Dr Ingrid Ehrmann Professor Alison Tyson-Capper Dr Gavin Clowry et al.	Binding site density enables paralog-specific activity of SLM2 and Sam68 proteins in Neurexin2 AS4 splicing control	2017
Dr Jennifer Munkley Karen Livermore Dr Prabhakar Rajan Professor David Elliott	RNA splicing and splicing regulator changes in prostate cancer pathology	2017
Dr Jennifer Munkley Dr Urszula McClurg Karen Livermore Dr Ingrid Ehrmann Professor Craig Robson et al.	The cancer-associated cell migration protein TSPAN1 is under control of androgens and its upregulation increases prostate cancer cell migration	2017
Dr Ingrid Ehrmann Caroline Dalgliesh Dr Yaobo Xu Dr Marina Danilenko Marie Maclennan et al.	A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior	2016
Karen Livermore Dr Jennifer Munkley Professor David Elliott	Androgen receptor in prostate cancer	2016
Dr Jannetta Steyn Professor David Elliott Dr Mauro Santibanez Koref Dr Michael Jackson	Circular RNA enrichment in platelets is a signature of transcriptome degradation	2016
Dr Ginikachukwu Izuogu Dr Mauro Santibanez Koref Professor David Elliott Dr Michael Jackson	Erratum to: PTESFinder: A computational method to identify post-transcriptional exon shuffling (PTES) events [BMC Bioinf. 2016; 17: 31]	2016
Dr Jennifer Munkley Karen Livermore Dr Katherine James Dr Brian Wilson Professor Craig Robson et al.	Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability	2016
Dr Jennifer Munkley Professor David Elliott	Hallmarks of glycosylation in cancer	2016
Dr Irina Neganova Dr Evgeniya Shmeleva Dr Jennifer Munkley Dr Valeria Chichagova Dr George Anyfantis et al.	JNK/SAPK signalling is essential for efficient reprogramming of human fibroblasts to induced pluripotent stem cells	2016
Dr Ingrid Ehrmann Professor David Elliott	STARs in the CNS	2016
Dr Sushma Grellscheid Dr Marina Danilenko Caroline Dalgliesh Yilei Liu Professor David Elliott et al.	Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68	2016
Dr Jennifer Munkley Professor David Elliott	Sugars and cell adhesion: the role of ST6GalNAc1 in prostate cancer progression	2016
Dr Jennifer Munkley Professor David Elliott	The role of glycans in the development and progression of prostate cancer	2016
Dr Andrew Best Dr Katherine James Gerald Hysenaj Professor Alison Tyson-Capper Professor David Elliott et al.	Transformer2 proteins protect breast cancer cells from accumulating replication stress by ensuring productive splicing of checkpoint kinase 1	2016
Dr Jennifer Munkley Professor Craig Robson Professor Hing Leung Dr Prabhakar Rajan Professor David Elliott et al.	Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer	2015
Alicia Madgwick Dr Peter Hanson Professor David Elliott Dr Christopher Morris Dr Julian Venables et al.	Neural Differentiation Modulates the Vertebrate Brain Specific Splicing Program	2015
Dr Jennifer Munkley Dr Brian Wilson Karen Livermore Dr Vasileios Floros Professor Craig Robson et al.	The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer	2015
Dr Jennifer Munkley Karen Livermore Dr Urszula McClurg Professor Craig Robson Dr Prabhakar Rajan et al.	The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells	2015
Dr Jacqueline Stockley Professor Craig Robson Professor David Elliott Professor Hing Leung Dr Prabhakar Rajan et al.	The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7	2015
Elaine Hong Dr Andrew Best Dr Hannah Gautrey Professor David Elliott Professor Alison Tyson-Capper et al.	Unravelling the RNA-Binding Properties of SAFB Proteins in Breast Cancer Cells	2015
Dr Veronika Boczonadi Dr Juliane Mueller Dr Angela Pyle Dr Jennifer Munkley Michele Giunta et al.	EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia	2014
Dr Jennifer Munkley Dr Prabhakar Rajan Caroline Dalgliesh Robert Jackson Professor Craig Robson et al.	A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation	2014
Andy Best Caroline Dalgliesh Elaine Hong Mahsa Kheirollahi Kouhestani Dr Yaobo Xu et al.	Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons	2014
Professor David Elliott	Illuminating the Transcriptome through the Genome	2014
Dr Andrew Best Caroline Dalgliesh Mahsa Kheirollahi Kouhestani Dr Marina Danilenko Dr Ingrid Ehrmann et al.	Tra2 protein biology and mechanisms of splicing control	2014
Andy Best Dr Ingrid Ehrmann Mahsa Kheirollahi Kouhestani Professor Alison Tyson-Capper Professor David Elliott et al.	Expression of Tra2ß in cancer cells as a potential contributory factor to neoplasia and metastasis	2013
Dr Sushma Grellscheid Dr Ingrid Ehrmann Caroline Dalgliesh Dr Marina Danilenko Professor David Elliott et al.	The splicing landscape is globally reprogrammed during male meiosis	2013
Dr Ingrid Ehrmann Caroline Dalgliesh Dr Marina Danilenko Moira Crosier Lynne Overman et al.	The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Neurexin Pre-mRNAs in the Brain	2013
Professor David Elliott Andy Best Caroline Dalgliesh Dr Ingrid Ehrmann Dr Sushma Grellscheid et al.	How does Tra2 beta protein regulate tissue-specific RNA splicing?	2012
Dr Elaine Hong Professor David Elliott Professor Alison Tyson-Capper	Identification of SAFB1 and SAFB2 Target Genes within the Oestrogen Receptor-Signalling Pathway in Breast Cancer Cells	2012
Elaine Hong Dr Hannah Gautrey Professor David Elliott Professor Alison Tyson-Capper	SAFB1 and SAFB2 mediated transcriptional repression: relevance in cancer	2012
Dr Sushma Grellscheid Caroline Dalgliesh Andy Best Yilei Liu Dr Ingrid Ehrmann et al.	Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development	2011
Dr Prabhakar Rajan Caroline Dalgliesh Pip Carling Dr Sushma Grellscheid Dr Kelly Coffey et al.	Identification of Novel Androgen-Regulated Pathways and mRNA Isoforms through Genome-Wide Exon-Specific Profiling of the LNCaP Transcriptome	2011
Dr Sushma Grellscheid Caroline Dalgliesh Dr Agata Rozanska Professor David Elliott	Molecular design of a splicing switch responsive to the RNA binding protein Tra2β	2011
Haya AL-Balool Dr Mark Wade Dr Jonathan Coxhead Professor Julie Irving Professor David Elliott et al.	Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant	2011
Yilei Liu Professor David Elliott	Coupling genetics and post-genomic approaches to decipher the cellular splicing code at a systemswide level	2010
Professor David Elliott	Coupling genetics and post-genomic approaches to decipher the cellular splicing code at a systems-wide level	2010
Dr Ingrid Ehrmann Professor David Elliott	Expression and functions of the start proteins Sam68 and T-Star in mammalian spermatogenesis	2010
Yilei Liu Dr Ingrid Ehrmann Professor David Elliott	Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-β	2010
Professor David Elliott	Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients	2010
Professor David Elliott Dr Prabhakar Rajan	The role of the RNA-binding protein Sam68 in mammary tumourigenesis	2010
Professor David Elliott Professor Craig Robson Professor Hing Leung	Alternative splicing and biological heterogeneity in prostate cancer	2009
Dr Sarra Ryan Professor David Elliott Professor David Ellison Professor Simon Bailey Professor Steven Clifford et al.	Amplification and overexpression of Hsa-miR-3ob, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma	2009
Professor David Elliott	Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regionsin pre-mRNA	2009
Dr Prabhakar Rajan Caroline Dalgliesh Dr Kaveh Emami Dr Emma Clark Professor Craig Robson et al.	Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies	2009
Professor David Elliott	The Germ Cell Nuclear Proteins hnRNP G-T and RBMY Activate a Testis-Specific Exon	2009
Dr Emma Clark Professor David Elliott Professor Craig Robson	Coupling transcription to RNA processing via the p68 DEAD box RNA helicase androgen receptor co-activator in prostate cancer	2008
Dr Ingrid Ehrmann Caroline Dalgliesh Anastasios Tsaousis Dr Ralf Kist Weiping Li et al.	Haploinsufficiency of the germ cell-specific nuclear RNA binding protein hnRNP G-T prevents functional spermatogenesis in the mouse	2008
Dr Prabhakar Rajan Dr Luke Gaughan Caroline Dalgliesh Dr Amira El-Sherif Professor Craig Robson et al.	Regulation of gene expression by the RNA-binding protein Sam68 in cancer	2008
Dr Emma Clark Dr Anne Coulson Caroline Dalgliesh Dr Prabhakar Rajan Professor Rakesh Heer et al.	The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer	2008
Dr Prabhakar Rajan Dr Luke Gaughan Caroline Dalgliesh Dr Amira El-Sherif Professor Craig Robson et al.	The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptor	2008
Caroline Dalgliesh Dr Julian Venables Professor David Elliott	Alternative RNA splicing complexes containing the scaffold attachment factor SAFB2	2007
Professor Karim Nayernia Dr Jae Ho Lee Dr Ingrid Ehrmann Professor David Elliott	From stem cells to germ cells and from germ cells to stem cells	2007
Dr Sushma Grellscheid Professor David Elliott	The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction	2007
Professor David Elliott Dr Sushma Grellscheid	Alternative RNA splicing regulation in the testis	2006
Professor Karim Nayernia Dr Jae Ho Lee Dr Ingrid Ehrmann Professor David Elliott	In Vitro-Differentiated Embryonic Stem Cells Give Rise to Male Gametes that Can Generate Offspring Mice	2006
Dr Alexandra Reis Dr Mark Levasseur Professor David Elliott Professor Keith Jones	The CRY box: A second APC^cdh1-dependent degron in mammalian cdc20	2006
Dr Jared Thornton Caroline Dalgliesh Dr Julian Venables Dr Ingrid Ehrmann Professor David Elliott et al.	The tumour-suppressor protein ASPP1 is nuclear in human germ cells and can modulate ratios of CD44 exon V5 spliced isoforms in vivo	2006
Professor David Elliott	Molecular markers for the assessment of postnatal male germ cell development in the mouse	2005
Professor David Elliott	Pairing, connecting, exchanging, pausing and pulling chromosomes	2005
Dr Alexander McDougall Professor David Elliott	Pairing, connecting, exchanging, pausing and pulling chromosomes	2005
Dr Ingrid Ehrmann Professor David Elliott	Post-transcriptional control in the male germ line	2005
Dr Julian Venables Caroline Dalgliesh Professor David Elliott	Up-regulation of the ubiquitous alternative splicing factor Tra2β causes inclusion of a germ cell-specific exon	2005
Professor David Elliott	A prevalent POLG CAG microsatellite length allele in humans and African great apes	2004
Dr Louise Hyslop Dr Victoria Nixon Dr Mark Levasseur Fiona Chapman Dr Alexander McDougall et al.	Ca²⁺-promoted cyclin B1 degradation in mouse oocytes requires the establishment of a metaphase arrest	2004
Professor David Elliott	Does Rbmy have a role in sperm development in mice? (vol 103, pg 330, 2003)	2004
Professor David Elliott	Erratum: Does Rbmy have a role in sperm development in mice? (Cytogenetic and Genome Research (2003) 103 (330-336))	2004
Emeritus Professor Stephen Jarvis Professor David Elliott Debra Morgan	Molecular markers for the assessment of' postnatal male germ cell development in the mouse	2004
Dr Julian Venables Caroline Dalgliesh Lindi Skitt Dr Jared Thornton Professor Keith Jones et al.	SIAH1 targets the alternative splicing factor T-STAR for degradation by the proteasome	2004
Professor David Elliott	The role of potential splicing factors including RBMY, RBMX, hnRNPG-T and STAR proteins in spermatogenesis	2004
Professor Michael Taggart Professor David Elliott	Absence of mDazl produces a final block on germ cell development at meiosis	2003
Professor David Elliott	Does Rbmy have a role in sperm development in mice?	2003
Professor David Elliott	Double immunolabeling by the RBM and the PLAP markers for identifying intratubular (in situ) germ cell neoplasia of the testis	2003
Professor David Elliott	Lack of RBM expression as a marker for carcinoma in situ of prepubertal dysgenetic testis	2003
Professor David Elliott	Pathways of post-transcriptional gene regulation in mammalian germ cell development	2003
Dr Julian Venables Professor David Elliott	tr-kit promotes the formation of a multimolecular complex composed by Fyn, PLCγ1 and Sam68	2003
Professor David Elliott	Localization of a specific germ cell marker, DAZL1, in testicular germ cell neoplasias	2002
Professor David Elliott	Localization of the germ cell-specific protein, hnRNP G-T, in testicular biopsies of azoospermic men	2002
Professor David Elliott	Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist	2002
Professor David Elliott	Intratubular germ cell neoplasia: Associated infertility and review of the diagnostic modalities	2001
Professor David Elliott	Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility	2001
Professor David Elliott	The contribution of RNA-binding motif (RBM) antibody to the histopathologic evaluation of testicular biopsies from infertile men	2001
Professor David Elliott	A mammalian germ cell-specific RNA binding protein interacts with ubiquitously expressed proteins involved in splice site selection	2000
Professor David Elliott Dr Julian Venables	An evolutionarily conserved germ cell-specific hnRNP is encoded by a retrotransposed gene	2000
Dr Julian Venables Professor David Elliott	RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing	2000
Professor David Elliott	Splicing and the single cell	2000
Dr Julian Venables Professor David Elliott	T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis	1999