Publications by Dr Nicholas Bown - ePrints

Browsing publications by Dr Nicholas Bown.

Newcastle Authors	Title	Year
Dr Laura Woodhouse Clark Crawford Dr Scott Marshall Dr Nicholas Bown Dr Elaine Willmore et al.	Assessment and targeting of the MDM2-p53 network in CLL	2015
Professor Tim Gray Dr Nicholas Bown	Crisis Within Social Capital? The Negative Impact on Natural Resources of Tension Between Household and Community Social Capital in a Migrant Ladino Enclave on Utila	2012
Sarah Nicholson Dr Nicholas Bown Professor Steven Clifford	A feasibility study of real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma in the United Kingdom	2011
Dr Nicholas Bown Professor John Lunec Professor Deborah Tweddle	A Multilocus Technique for Risk Evaluation of Patients with Neuroblastoma	2011
Professor Anthony Moorman Dr Lucy Chilton Dr Jennifer Wilkinson Hannah Ensor Dr Nicholas Bown et al.	A population-based cytogenetic study of adults with acute lymphoblastic leukemia	2010
Dr Nicholas Bown Professor Christine Harrison FRCPath FMedSci	Cytogenetics of long-term survivors of ETV6-RUNX1 fusion positive acute lymphoblastic leukemia	2010
Sarah Nicholson Dr Nicholas Bown Professor Steven Clifford	Establishment of real-time centralised pathology review (CPR) and molecular diagnostics for medulloblastoma in the United Kingdom	2010
Dr Fathi Azribi Dr Nicholas Bown Dr Petra Dildey Stephen Clark Professor Ruth Plummer et al.	Extraosseous Pericardial Ewing's Sarcoma	2010
Sarina Sulong Professor Anthony Moorman Professor Julie Irving Marian Case Professor Simon Bailey et al.	A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups	2009
Professor Steven Clifford Dr Nicholas Bown	A feasibility study of real-time biological characterisation of medulloblastoma in the United Kingdom	2009
Kate Wilson Marian Case Lynne Minto Professor Simon Bailey Dr Nicholas Bown et al.	Flow minimal residue disease monitoring of candidate leukemic stem cells defined by the immunophenotype, CD34⁺CD38^lowCD19⁺ in B-lineage childhoood acute lymphoblastic leukemia	2009
Professor Andrew Gennery Dr Nicholas Bown Dr Terence Flood Professor Andrew Cant Dr Mario Abinun et al.	Assessment of reduced intensity conditioning regimens for haematopoietic stem cell transplantation in primary immunodeficiency	2008
Professor Roderick Skinner Dr Mark Velangi Dr Nicholas Bown	Donor lymphocyte infusions for post-transplant relapse of refractory anemia with excess blasts and monosomy 7	2008
Professor Anne Dickinson Dr Nicholas Bown Professor Andrew Cant Dr Mario Abinun Professor Andrew Gennery et al.	Long-term immune reconstitution after anti-CD52-treated or anti-CD34-treated hematopoietic stem cell transplantation for severe T-lymphocyte immunodeficiency	2008
Marian Case Elizabeth Matheson Lynne Minto Dr Nicholas Bown Professor Simon Bailey et al.	Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia	2008
Dr Michael Griffiths Dr Nicholas Bown	Ploidy and karyotype complexity are powerful prognostic indicators in the Ewing's sarcoma family of tumors: A study by the United Kingdom cancer cytogenetics and the children's cancer and leukaemia group	2008
Marian Case Elizabeth Matheson Lynne Minto Professor Christine Harrison FRCPath FMedSci Dr Nicholas Bown et al.	Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting	2008
Dr Nicholas Bown	Comparison of MLPA and interphase FISH in chronic lymphocytic leukaemia	2007
Dr Jane Carr-Wilkinson Dr Nicholas Bown Marian Case Dr Andrew Hall Professor John Lunec et al.	High-resolution analysis of allelic imbalance in neuroblastoma cell lines by single nucleotide polymorphism arrays	2007
Daniel Routledge Dr David Bourn Dr Nicholas Bown Mike Cole Professor Andrew Gennery et al.	Quantitative assessment of mixed chimerism in allogeneic stem cell transplant patients - A comparison of molecular genetic and cytogenetic approaches	2007
Dr Andrew Hall Sarina Sulong Professor Christine Harrison FRCPath FMedSci Lynne Minto Dr Nicholas Bown et al.	Assessment of aneuploidy in childhood acute lymphoblastic leukaemia using high density oligonucleotide arrays.	2006
Dr Jackie Langdon Dr Jayne Lamont Dr Debbie Scott Dr Nicholas Bown Professor David Ellison et al.	Combined genome-wide allelotyping and copy number analysis identify frequent genetic losses without copy number reduction in medulloblastoma	2006
Sarina Sulong Professor Julie Irving Marian Case Lynne Minto Dr Nicholas Bown et al.	Comprehensive analysis of p16(INK4a) in childhood acute lymphoblastic leukemia reveals homozygous deletion, haploinsufficiency and acquired isodisomy at the 9p locus with intact p16(INK4a).	2006
Professor Julie Irving Lynne Minto Elizabeth Matheson Marian Case Professor Simon Bailey et al.	Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse.	2006
Professor Anthony Moorman Dr Nicholas Bown Professor Christine Harrison FRCPath FMedSci	PAX5-ETV6 fusion in acute lymphoblastic leukaemia des not define the dic(9;12)	2006
Dr Michael Griffiths Dr Hazel Powell Dr Ann Curtis Dr Nicholas Bown	Acquired isodisomy for chromosome 13 is common and associated with FLT3-itd mutations in AML	2005
Dr Ann Curtis Dr Nicholas Bown	Acquired Isodisomy for chromosome 13 is common in AML, and associated with FLT3-itd mutations	2005
Professor Julie Irving Clare Bloodworth Dr Nicholas Bown Marian Case Dr Linda Hogarth et al.	Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis	2005
Dr Hazel Powell Dr Ann Curtis Dr Nicholas Bown Dr Philip Taylor	No correlation between trisomy 13 and FLT3 duplication in acute myeloid leukemia	2005
Dr Nicholas Bown Dr David Bourn	Quantitative assessment of mixed chimerism in bone marrow transplant patients: a comparison of molecular genetic and cytogenetic approaches.	2005
Dr Nicholas Bown Dr Hazel Powell Dr Ann Curtis	Incidence and clinical significance of FLT3 internal tandem duplications in acute myeloid leukaemia.	2004
Dr Andrew Hall Clare Bloodworth Dr Linda Hogarth Dr Nicholas Bown Professor Julie Irving et al.	Loss of heterozygosity in childhood acute lymphoblastic leukaemia detected by genome-wide microarray single nucleotide polymorphism analysis	2004
Dr John Byrne Julie Freeman-Edward Gavin Cuthbert Dr Nicholas Bown	Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions	2003
Professor Anthony Moorman Dr Nicholas Bown Dr Penelope Taylor Professor Stephen Proctor	Population-based study of unselected acute myeloid leukemia cases reveals distinct cytogenetic pathways analogous to therapy-related AML/MDS	2003
Dr Nicholas Bown Julie Freeman-Edward Professor John Lunec Dr Katia Mazzocco Steven O'Neill et al.	Quality assessment of genetic markers used for therapy stratification	2003
Dr Mark Velangi Dr Michael Reid Dr Nicholas Bown Professor Graham Jackson Professor Stephen Proctor et al.	Acute lymphoblastic leukaemia of the L3 subtype in adults in the Northern health region of England 1983-99	2002
Dr Nicholas Bown Simon Cotterill Dr Michael Griffiths	Cytogenetic abnormalities and clinical outcome in Wilms tumor: A study by the UK Cancer Cytogenetics Group and the UK Children's Cancer Study Group	2002
Dr Nicholas Bown	Diagnostic detection of AML1/ETO gene fusion by polymerase chain reaction	2002
Dr Anne Lennard Dr Nicholas Bown	Late-appearing MLL rearrangement arising as a secondary change in adult acute myeloid leukemia	2002
Dr Seamus O'Neill Dr Nicholas Bown	Comparative genomic hybridization in pineal parenchymal tumors	2001
Dr Maria Lastowska Simon Cotterill Dr Nicholas Bown Dr Katia Mazzocco Professor Andrew Pearson et al.	Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors	2001
Gavin Cuthbert Julie Freeman-Edward Dr Anne Lennard Professor Stephen O'Brien Dr Nicholas Bown et al.	Der(9) deletions and response to STI571(Glivec (R)) treatment in chronic phase CML patients.	2001
Professor Deborah Tweddle Professor Archibald Malcolm Dr Nicholas Bown Professor Andrew Pearson Professor John Lunec et al.	Evidence for the development of p53 mutations after cytotoxic therapy in a neuroblastoma cell line	2001
Dr Maria Lastowska Dr Nicholas Bown Professor John Lunec Professor Tom Strachan Professor Andrew Pearson et al.	Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma	2001
Dr Maria Lastowska Dr Nicholas Bown Professor John Lunec Professor Tom Strachan Professor Andrew Pearson et al.	Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma	2001
Gavin Cuthbert Professor Christine Harrison FRCPath FMedSci Dr Michael Griffiths Dr Nicholas Bown	MLL amplification in acute leukaemia: a United Kingdom Cancer Cytogenetics Group (UKCCG) study	2000
Simon Cotterill Dr Nicholas Bown	Cytogenetically cryptic AML1 - ETO and CBFβ - MYH11 gene rearrangements: Incidence in 412 cases of acute myeloid leukaemia	2000
Dr Nicholas Bown Professor John Lunec Professor Archibald Malcolm Professor Andrew Pearson	Fluorescence in situ hybridization techniques for the rapid detection of genetic prognostic factors in neuroblastoma	2000
Gavin Cuthbert Karen Thompson Dr Nicholas Bown	Sensitivity of FISH in detection of MLL traslocations	2000
Dr Nicholas Bown Simon Cotterill Dr Maria Lastowska Dr Seamus O'Neill Professor Andrew Pearson et al.	Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma	1999
Dr Maria Lastowska Dr Nicholas Bown Professor John Lunec Professor Tom Strachan Professor Andrew Pearson et al.	Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines	1998
Simon Cotterill Professor Andrew Pearson Dr Nicholas Bown	Gain of chromosome arm 17q predicts unfavourable outcome in neuroblastoma patients	1997
Dr Maria Lastowska Professor Andrew Pearson Dr John Wolstenholme Dr Nicholas Bown	Promiscuous translocations of chromosome arm 17q in human neuroblastomas	1997
Dr Nicholas Bown Professor Archibald Malcolm Dr Michael Reid Professor Andrew Pearson	Solid alveolar rhabdomyosarcoma with a t(2;13)	1995
Dr Nicholas Bown Dr Michael Reid Professor Archibald Malcolm Emeritus Professor Alan Craft Professor Andrew Pearson et al.	Cytogenic abnormalities of small round-cell tumors	1994
Dr Nicholas Bown Dr Michael Reid Professor Archibald Malcolm Professor Andrew Pearson	Rapid detection of prognostic genetic factors in neuroblastoma using fluorescence in situ hybridisation on tumour imprints and bone marrow smears. United Kingdom Children's Cancer Study Group	1994
Dr Penelope Taylor Dr Michael Reid Dr Nicholas Bown Dr Peter Hamilton Professor Stephen Proctor et al.	Acute myeloid leukemia in the over 55s: A population-based study of incidence, treatment and outcome	1993
Dr Nicholas Bown Professor Andrew Pearson Dr Michael Reid	High incidence of constitutional balanced translocations in neuroblastoma	1993
Dr Michael Reid Dr Peter Saunders Dr Nicholas Bown Emeritus Professor Alan Craft Professor Archibald Malcolm et al.	Alveolar rhabdomyosarcoma infiltrating bone marrow at presentation: the value to diagnosis of bone marrow trethine biopsy specimens	1992
Dr Nicholas Bown Professor Andrew Pearson Dr Michael Reid	Cytogenetic studies of childhood solid tumors	1989
Dr Nicholas Bown Professor Andrew Pearson Dr Michael Reid	Cytogenetic studies of pediatric solid tumors	1989
Dr Nicholas Bown Professor Andrew Pearson Professor Archibald Malcolm	Cytogenetic abnormalities in a primitive neuroectodermal tumor	1988
Professor Andrew Pearson Dr Michael Reid Dr Nicholas Bown Professor Archibald Malcolm Emeritus Professor Alan Craft et al.	Cytogenetic investigations of solid tumours of children	1988
Dr Nicholas Bown Professor Andrew Pearson Peter Crawford Emeritus Professor Robert Perry	Multiple chromosome rearrangements in a childhood ependymoma	1988
Dr Nicholas Bown Dr Michael Reid Professor Andrew Pearson Professor Archibald Malcolm Emeritus Professor Alan Craft et al.	Cytogenic investigations in the assessment of response to treatment in neuroblastoma	1987