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Lookup NU author(s): James Alastair McLaughlin McLaughlin, Dr Goksel Misirli, Professor Anil Wipat
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© Copyright © 2020 McLaughlin, Beal, Mısırlı, Grünberg, Bartley, Scott-Brown, Vaidyanathan, Fontanarrosa, Oberortner, Wipat, Gorochowski and Myers.The Synthetic Biology Open Language (SBOL) is a community-developed data standard that allows knowledge about biological designs to be captured using a machine-tractable, ontology-backed representation that is built using Semantic Web technologies. While early versions of SBOL focused only on the description of DNA-based components and their sub-components, SBOL can now be used to represent knowledge across multiple scales and throughout the entire synthetic biology workflow, from the specification of a single molecule or DNA fragment through to multicellular systems containing multiple interacting genetic circuits. The third major iteration of the SBOL standard, SBOL3, is an effort to streamline and simplify the underlying data model with a focus on real-world applications, based on experience from the deployment of SBOL in a variety of scientific and industrial settings. Here, we introduce the SBOL3 specification both in comparison to previous versions of SBOL and through practical examples of its use.
Author(s): McLaughlin JA, Beal J, Misirli G, Grunberg R, Bartley BA, Scott-Brown J, Vaidyanathan P, Fontanarrosa P, Oberortner E, Wipat A, Gorochowski TE, Myers CJ
Publication type: Article
Publication status: Published
Journal: Frontiers in Bioengineering and Biotechnology
Year: 2020
Volume: 8
Online publication date: 11/09/2020
Acceptance date: 31/07/2020
Date deposited: 12/01/2021
ISSN (electronic): 2296-4185
Publisher: Frontiers Media S.A.
URL: https://doi.org/10.3389/fbioe.2020.01009
DOI: 10.3389/fbioe.2020.01009
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