Publications by Professor Caroline Relton - ePrints

Browsing publications by Professor Caroline Relton.

Newcastle Authors	Title	Year
Natassia Robinson Dr Heather Brown Professor Mark Pearce Professor Caroline Relton Dr Viviana Albani et al.	Childhood DNA methylation as a marker of early life rapid weight gain and subsequent overweight	2021
Professor Caroline Relton	Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children	2020
Dr Richard Howey Dr So-Youn Shin Professor Caroline Relton Professor Heather Cordell	Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data	2020
Professor Caroline Relton	Corrigendum to ‘Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children’ [Psychoneuroendocrinology 113 March (2020) 104484] (Psychoneuroendocrinology (2020) 113, (S0306453019304755), (10.1016/j.psyneuen.2019.104484))	2020
Ushma Shah Professor Mark Walker Professor Caroline Relton Dr Hannah Elliott	Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation	2019
Professor Caroline Relton	Is high vitamin B12 status a cause of lung cancer?	2019
Professor Caroline Relton	Sensitive Periods for the Effect of Childhood Adversity on DNA Methylation: Results From a Prospective, Longitudinal Study	2019
Professor Caroline Relton	Vitamin B6 catabolism and lung cancer risk: Results from the Lung Cancer Cohort Consortium (LC3)	2019
Dr Kate Potter Professor Caroline Relton	Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics	2018
Professor Caroline Relton Dr Paul Brennan	Impaired functional vitamin B6 status is associated with increased risk of lung cancer	2018
Dr Kate Potter Professor Anthony Moorman Professor Caroline Relton Professor John Mathers Dr Gordon Strathdee et al.	Maternal red blood cell folate and infant vitamin B12 status influence methylation of genes associated with childhood acute lymphoblastic leukaemia	2018
Dr Frauke Becker Professor Caroline Relton	Women’s preferences for alternative financial incentive schemes for breastfeeding: A discrete choice experiment	2018
Professor Caroline Relton Dr Paul Brennan	Circulating concentrations of biomarkers and metabolites related to vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations	2017
Professor Caroline Relton	Circulating vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort	2016
Professor Caroline Relton	DNA Methylation and BMI: Investigating Identified Methylation Sites at HIF3A in a Causal Framework	2016
Jessica Timms Professor Caroline Relton Professor Judith Rankin Dr Gordon Strathdee Dr Jill McKay et al.	DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukaemia	2016
Professor Caroline Relton	Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies	2016
Professor Caroline Relton	Systematic identification of genetic influences on methylation across the human life course	2016
Professor Caroline Relton	A prospective study of one-carbon metabolism biomarkers and cancer of the head and neck and esophagus	2015
Sanne van Otterdijk Jean Norden Professor Anne Dickinson Professor Mark Pearce Professor Caroline Relton et al.	Aberrations in DNA methylation are detectable during remission of acute lymphoblastic leukemia and predict patient outcome	2015
Dr So-Youn Shin Professor Caroline Relton	Alcohol intake and cardiovascular risk factors: A Mendelian randomisation study	2015
Dr So-Youn Shin Professor Caroline Relton	Characterization of whole-genome autosomal differences of DNA methylation between men and women	2015
Professor Caroline Relton Professor Anil Wipat Dr Keith Flanagan Dr Allyson Lister	Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES)	2015
Professor Caroline Relton	Longitudinal analysis of DNA methylation associated with birth weight and gestational age	2015
Professor Caroline Relton	Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children	2015
Professor Caroline Relton	Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis	2015
Professor Caroline Relton	Prenatal Exposure to Maternal Cigarette Smoking and DNA Methylation: Epigenome-Wide Association in a Discovery Sample of Adolescents and Replication in an Independent Cohort at Birth through 17 Years of Age	2015
Professor Caroline Relton	Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)	2015
Professor Caroline Relton	Approaches for drawing causal inferences from epidemiological birth cohorts: A review	2014
Professor Caroline Relton	Circulating biomarkers of tryptophan and the kynurenine pathway and lung cancer risk	2014
Professor Caroline Relton	Differences in smoking associated DNA methylation patterns in South Asians and Europeans	2014
Dr Eva Morales Dr Alexandra Groom Professor Caroline Relton	DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort	2014
Dr Kamil Sitarz Dr Hannah Elliott Betul Karaman Professor Caroline Relton Professor Patrick Chinnery et al.	Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts	2014
Professor Caroline Relton	What is it about boys?	2014
Dr Sara Brown Dr Stephen Turner Professor Caroline Relton Professor Sir John Burn Dr Simon Meggitt et al.	Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects	2013
Dr Hannah Elliott Professor Caroline Relton	DNA methylation, cardio metabolic risk and type 2 diabetes in south Asians and Europeans	2013
Dr Claire Wood Dr Robert Tinnion Dr Srinivasa Korada Professor Timothy Cheetham Professor Caroline Relton et al.	Growth and metabolic outcome in adolescents born preterm (GROWMORE): follow-up protocol for the Newcastle preterm birth growth study (PTBGS)	2013
Dr Jill McKay Dr Alexandra Groom Professor Dianne Ford Lisa Coneyworth Professor John Mathers et al.	Influence of DNMT Genotype on Global and Site Specific DNA Methylation Patterns in Neonates and Pregnant Women	2013
Addison Palomino Doza Dr Ana Topf Dr John O'Sullivan Professor Caroline Relton Professor Judith Goodship et al.	Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot	2013
Professor Judith Goodship Dr Darroch Hall Dr Ana Topf Valentina Mamasoula Dr Helen Griffin et al.	A Common Variant in the PTPN11 Gene Contributes to the Risk of Tetralogy of Fallot	2012
Dr Naweed Sattar Professor Caroline Relton	Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure	2012
Valerie Turcot Dr Alexandra Groom Professor Mark Pearce Dr Kate Potter Professor Nicholas Embleton et al.	Bioinformatic selection of putative epigenetically regulated loci associated with obesity using gene expression data	2012
Professor Caroline Relton Dr Alexandra Groom Dr Daniel Swan Professor Nicholas Embleton Professor Mark Pearce et al.	DNA methylation patterns in cord blood DNA and body size in childhood	2012
Dr Kate Potter Professor Caroline Relton	Epigenetic Epidemiology. Karin B. Michels (ed)	2012
Professor Patrick Chinnery Dr Hannah Elliott Professor Gavin Hudson Professor David Samuels Professor Caroline Relton et al.	Epigenetics, epidemiology and mitochondrial DNA diseases	2012
Dr Jill McKay Dr Alexandra Groom Dr Kate Potter Lisa Coneyworth Professor Dianne Ford et al.	Genetic and Non-Genetic Influences during Pregnancy on Infant Global and Site Specific DNA Methylation: Role for Folate Gene Variants and Vitamin B^₁₂	2012
Dr Kate Potter Dr Jane Ng Professor Caroline Relton	Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA₅-CHRNA₃-CHRNB₄) interacts with maternal self-reported smoking status during pregnancy to influence birth weight	2012
Professor Mark Pearce Dr Kate Potter Laura Barrett Professor Louise Parker Professor John Mathers et al.	Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles	2012
Professor Mark Pearce Dr Kay Mann Professor Caroline Relton Emeritus Professor Roger Francis Emeritus Professor Jimmy Steele CBE et al.	How the Newcastle Thousand Families birth cohort study has contributed to the understanding of the impact of birth weight and early life socioeconomic position on disease in later life	2012
Professor Caroline Relton	Is epidemiology ready for epigenetics?	2012
Professor Caroline Relton	Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans	2012
Dr Alexandra Groom Professor Caroline Relton	People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population	2012
Dr Alexandra Groom Dr Kate Potter Valerie Turcot Professor Mark Pearce Professor Nicholas Embleton et al.	Postnatal Growth and DNA Methylation Are Associated With Differential Gene Expression of the TACSTD2 Gene and Childhood Fat Mass	2012
Professor Caroline Relton	Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?	2012
Laura Barrett Professor Caroline Relton	The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities	2012
Professor Caroline Relton	Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease	2012
Professor Mark Pearce Dr Alexandra Groom Professor Caroline Relton Professor Louise Parker Emeritus Professor Roger Francis et al.	Associations between sex hormones and bone mineral density and bone resorption in 50 year old men: The Newcastle thousand families study	2011
Professor Mark Pearce Dr Alexandra Groom Professor Caroline Relton Emeritus Professor Roger Francis	Birth weight and early socio-economic disadvantage as predictors of sex hormones and sex hormone binding globulin in men at age 49–51 years	2011
Dr Kathryn Parkinson Professor Mark Pearce Professor Caroline Relton Professor Ann Le Couteur Professor Ashley Adamson et al.	Cohort Profile: The Gateshead Millennium Study	2011
Dr Jill McKay Professor Dianne Ford Professor Caroline Relton Professor John Mathers	Consequences of Folate Depletion during Development for DNA Methylation and Gene Expression in the Fetal Mouse	2011
Professor Caroline Relton Dr Alexandra Groom Dr Daniel Swan Professor Nicholas Embleton Professor Mark Pearce et al.	DNA Methylation Patterns in Cord Blood DNA Predict Body Size in Childhood	2011
Dr Alexandra Groom Dr Hannah Elliott Professor Nicholas Embleton Professor Caroline Relton	Epigenetics and child health: basic principles	2011
Dr Jill McKay Dr Long Xie Professor Caroline Relton Professor Dianne Ford Professor John Mathers et al.	Folate Depletion during Development Causes Gene Expression Changes in Fetal and Adult Mouse Liver	2011
Professor Caroline Relton	Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC	2011
Dr Jill McKay Professor Caroline Relton Professor Dianne Ford Professor John Mathers	Maternal folate supply and sex influence gene-specific DNA methylation in the fetal gut	2011
Dr Alexandra Groom Dr Kate Potter Valerie Turcot Professor Mark Pearce Professor Nicholas Embleton et al.	Postnatal Growth Is Associated with DNA Methylation and Childhood Adiposity: Using Genetic Variation to Infer the Direction of Causation	2011
Professor Caroline Relton	Smoking, Secondhand Smoke, and Cotinine Levels in a Subset of EPIC Cohort	2011
Professor Mark Pearce Professor Caroline Relton Dr Alexandra Groom Emeritus Professor Roger Francis	A lifecourse study of bone resorption in men ages 49-51 years: The Newcastle Thousand Families cohort study	2010
Professor Caroline Relton	Epigenetic Epidemiology of Common Complex Disease: Prospects for Prediction, Prevention, and Treatment	2010
Professor Caroline Relton	Genetic selection? A study of individual variation in the enzymes of folate metabolism	2010
Professor John Mathers Dr Gordon Strathdee Professor Caroline Relton	Induction of Epigenetic Alterations by Dietary and Other Environmental Factors	2010
Dr Alison Sutherland David Kim Professor Caroline Relton Professor John Hesketh	Polymorphisms in the selenoprotein S and 15-kDa selenoprotein genes are associated with altered susceptibility to colorectal cancer	2010
Professor Caroline Relton Dr Paul Brennan	Serum B vitamin levels and risk of lung cancer	2010
Professor Caroline Relton Dr Alexandra Groom Dr Hannah Elliott Dr Jill McKay Professor Mark Pearce et al.	Epigenetic Epidemiology: Evidence for the Role of Epigenetic Variation in Complex Disease	2009
Dr Sara Brown Professor Caroline Relton Professor Heather Cordell Professor Nick Reynolds	Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children	2009
Dr Tevfik Dorak Professor Caroline Relton Professor Louise Parker Dr Andrew Hall	Hereditary Hemochromatosis Gene (HFE) Variants are Associated with Birth Weight and Childhood Leukemia Risk	2009
Professor Mark Pearce Professor Caroline Relton Professor Louise Parker Professor Nigel Unwin	Sex differences in the association between infant feeding and blood cholesterol in later life: the Newcastle thousand families cohort study at age 49-51 years	2009
Dr Jill McKay Professor Dianne Ford Professor Caroline Relton Professor John Mathers	Bioinformatic interrogation of expression array data to identify nutritionally regulated genes potentially modulated by DNA methylation	2008
Dr Sara Brown Professor Caroline Relton Professor Sir John Burn Professor Heather Cordell Professor Nick Reynolds et al.	Filaggrin mutations in atopic eczema: genotype-phenotype correlation	2008
Adillah Binti Yusof Professor Caroline Relton Dr Ian Wilson Professor Sir John Burn Professor Nick Reynolds et al.	Filaggrin null mutations and childhood atopic eczema: A population-based case-control study	2008
Dr Sara Brown Professor Caroline Relton Dr Ian Wilson Professor Sir John Burn Professor Nick Reynolds et al.	Filaggrin null mutations in mild-moderate atopic eczema: a population-based case-control study	2008
Professor Mark Pearce Professor Caroline Relton	Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey	2008
Dr Hannah Elliott Dr David Samuels James Eden Professor Caroline Relton Professor Patrick Chinnery et al.	Pathogenic Mitochondrial DNA Mutations Are Common in the General Population	2008
Dr Sara Brown Professor Caroline Relton Dr Simon Meggitt Professor Nick Reynolds Professor Heather Cordell et al.	Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema	2008
Professor Mark Pearce Professor Caroline Relton Professor Nigel Unwin Professor Ashley Adamson	The relation between diarrhoeal episodes in infancy and both blood pressure and sodium intake in later life: The Newcastle Thousand Families Study	2008
Professor Caroline Relton Professor Mark Pearce Dr John O'Sullivan	The relationship between gestational age, systolic blood pressure and pulse pressure in children	2008
Rachel MacKay Professor Caroline Relton Dr Tevfik Dorak	An HLA and leukaemia association study without HLA typing	2007
Dr Alexandra Groom Professor Caroline Relton Dr Jill McKay Laura Steedman Professor John Mathers et al.	DNA methylation status at the Igf2 locus in offspring of a mouse model of maternal diet-induced obesity	2007
Dr Jill McKay Professor Caroline Relton Professor Dianne Ford Professor John Mathers	Effects of dietary zinc supply during pregnancy on foetal liver DNA methylation of the insulin-like growth factor 2 (Igf2) gene in C57BL/J6 mice	2007
Professor Caroline Relton	Genetic epidemiologic studies of preterm birth: guidelines for research	2007
Professor Caroline Relton	Genetic epidemiologic studies of preterm birth: studies of disease or of "rescue by birth"?	2007
Professor Caroline Relton Dr Alexandra Groom Dr Jill McKay Professor Dianne Ford Professor John Mathers et al.	Polymorphic variation in DNA methyltransferase genes in relation to birth weight, smoking and folate status	2007
Professor Caroline Relton Dr Tevfik Dorak	Polymorphic variation in the haemochromatosis gene is associated with increased birth weight	2007
Professor Caroline Relton	Reply	2007
Professor Caroline Relton	Type 2 diabetes TCF7L2 risk genotypes alter birth weight: A study of 24,053 individuals	2007
Professor Caroline Relton	DNA repair gene polymorphisms in relation to chromosome aberration frequencies in retired radiation workers	2006
Professor Caroline Relton	Genotype profiles of loci encoding DNA repair enzymes in newborn and elderly populations: No evidence of association with longevity	2006
Professor Caroline Relton Gordon Taylor Professor Patrick Chinnery Emeritus Professor Doug Turnbull	Mitochondrial DNA mutations in individuals occupationally exposed to ionizing radiation	2006
Professor Caroline Relton Professor Mark Pearce Dr John O'Sullivan	The relationship between gestational age and pulse pressure in children	2006
Professor Caroline Relton Professor Mark Pearce Professor Sir John Burn Professor Louise Parker	An investigation of folate-related genetic factors in the determination of birthweight	2005
Professor Caroline Relton	DNA repair gene polymorphisms in relation to chromosome aberration frequencies in retired radiation workers	2005
Professor Caroline Relton Professor Mark Pearce Professor Sir John Burn	Folate Status and Genetic Selection	2005
Professor Caroline Relton Professor Judith Rankin	Folic acid - the challenge of unplanned pregnancy and social deprivation	2005
Professor Caroline Relton Donna Hammal Professor Judith Rankin Professor Louise Parker	Folic acid supplementation and social deprivation	2005
Professor Mark Pearce Professor Nigel Unwin Professor Caroline Relton Emeritus Professor Sir George Sir George Alberti Professor Louise Parker et al.	Lifecourse determinants of fasting and post-challenge glucose at age 50 years: The Newcastle thousand families study	2005
Professor Caroline Relton Professor Mark Pearce Professor Louise Parker	The influence of erythrocyte folate and serum vitamin B₁₂ status on birth weight	2005
Professor Caroline Relton Donna Hammal Professor Louise Parker Professor Sir John Burn	DNA repair gene polymorphisms, pre-natal factors and the frequency of somatic mutations in the glycophorin-A gene among healthy newborns	2004
Professor Caroline Relton Professor Mark Pearce James Laffey Dr Sally Lynch Professor Sir John Burn et al.	Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population	2004
Professor Caroline Relton Professor Sir John Burn	Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy	2004
Professor Caroline Relton Professor Sir John Burn	Thymidylate synthase repeat polymorphisms and risk of neural tube defects in a population from the northern United Kingdom	2004
Professor Caroline Relton Sumit Burkul	Folic acid - changes in women's knowledge	2003
Professor Caroline Relton Dr Sally Lynch	Genetic susceptibility to neural tube defect pregnancy varies with offspring phenotype	2003
Professor Caroline Relton Professor Andrew Fisher Professor Sir John Burn	Polymorphisms of the DNA repair gene XRCC1 and the frequency of somatic mutations at the glycophorin A locus in newborns	2002
Professor Caroline Relton	Polymorphisms of the DNA repair gene XRCC1 and the frequency of somatic mutations at the glycophorin A locus in newborns	2002