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Browsing publications by Dr Jeremy Palmer.

Newcastle AuthorsTitleYearFull text
Dr Min Cao
Dr Alison Day
Dr Martin Galler
Heather Latimer
Tom Foy
et al.
A peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanisms2023
Lucy Gee
Dr Ben Barron-Millar
Dr Marco Zaki
Dr Saimir Luli
Rachel Burgoyne
et al.
Anti–Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct–Ligated Mice2023
Dr Olivier Govaere
Dr Rebecca Darlay
Dr Julien Peltier
Dr Jeremy Palmer
Dr Massimo Younes
et al.
Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease2022
Dr Aaron Wetten
Dr Laura Ogle
Dr George Mells
Dr Vinod Hegade
Dr Laura Jopson
et al.
Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis?2022
Dr Sam Tingle
Dr Emily Thompson
Lucy Bates
Dr Ibrahim Ibrahim
Dr Olivier Govaere
et al.
Pharmacological testing of therapeutics using normothermic machine perfusion: A pilot study of 2,4-dinitrophenol delivery to steatotic human livers2022
Dr Claire Granger
Professor Chris Lamb
Professor Nicholas Embleton
Lauren Beck
Andrea Masi
et al.
sIgA in preterm infants: determination of normal values in breast milk and stool2022
Professor David Jones
Dr Aaron Wetten
Dr Ben Barron-Millar
Dr Laura Ogle
Dr George Mells
et al.
The relationship between disease activity and UDCA response criteria in primary biliary cholangitis: A cohort study2022
Dr Claire Granger
Professor Nicholas Embleton
Dr Jeremy Palmer
Professor Chris Lamb
Professor Janet Berrington
et al.
Maternal breastmilk, infant gut microbiome and the impact on preterm infant health2021
Dr Alistair Leitch
Dr Ibrahim Ibrahim
Dr Tarek Mamdouh Abdelghany
Dr Alex Charlton
Clair Roper
et al.
The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver2021
Dr Ben Barron-Millar
Dr Laura Ogle
Emeritus Professor John Kirby
Dr Jeremy Palmer
Dr Laura Jopson
et al.
The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis2021
Professor Quentin Anstee
Dr Rebecca Darlay
Dr Simon Cockell
Dr Olivier Govaere
Dr Dina Tiniakos
et al.
Genome-Wide Association Study of Non-Alcoholic Fatty Liver and Steatohepatitis in a Histologically-Characterised Cohort2020
Dr Alistair Leitch
Dr Tarek Mamdouh Abdelghany
Dr Phillip Probert
Dr Stephanie Meyer
Dr Jeremy Palmer
et al.
The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects2020
Dr Olivier Govaere
Dr Simon Cockell
Dr Dina Tiniakos
Dr Rachel Queen
Dr Massimo Younes
et al.
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis2020
Dr Phillip Probert
Dr Alistair Leitch
Dr Michael Dunn
Dr Stephanie Meyer
Dr Jeremy Palmer
et al.
Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis2018
Dr Emma Scott
Dr Jeremy Palmer
Professor Quentin Anstee
Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD2017
Dr Phillip Probert
Dr Jeremy Palmer
Dr Aimen Amer
Steven White
Professor David Jones
et al.
Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1′-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism2016
Dr Jess Dyson
Dr Jeremy Palmer
Dr Lin Lee Wong
Dr Stuart Kendrick
Professor David Jones
et al.
Understanding the importance of pro- and anti-inflammatory cytokines in autoimmune hepatitis2016
Dr Edwin Wong
Dr Jeremy Palmer
Professor Neil Sheerin
Dr Isabel Pappworth
FH1-5(18-20) ameliorates experimental C3 glomerulopathy; generation and testing of a murine version for further pre-clinical experiments2015
Dr Jeremy Palmer
Dr Yang-Lin Liu
Professor Chris Day
Professor Ann Daly
Professor Quentin Anstee
et al.
Mechanistic Study of TM6SF2 in NAFLD pathogenesis: Stably transfected Huh7 cells over-expressing the TM6SF2 E167K variant exhibit greater levels of oxidative stress2015
Dr Laura Jopson
Emerita Professor Julia Newton
Dr Jeremy Palmer
Achilleas FLOUDAS
Professor John Isaacs
et al.
RITPBC: B-Cell Depleting Therapy (rituximab) as a treatment for fatigue in Primary Biliary Cirrhosis: study protocol for a randomised controlled trial2015
Dr Laura Jopson
Emerita Professor Julia Newton
Denise Howel
Dr Jeremy Palmer
Professor John Isaacs
et al.
RITPBC: B-cell depleting therapy (RITUXIMAB) as a treatment for fatigue in primary biliary cirrhosis: study protocol for a randomised controlled trial2015
Dr Jeremy Palmer
Professor David Jones
Dr Jess Dyson
Emeritus Professor John Kirby
Understanding the Mechanisms Underpinning Treatment Non-Response in Primary Biliary Cirrhosis: A Tool for Treatment Stratification2014
Dr Jeremy Palmer
Dr Jess Dyson
Professor David Jones
Emeritus Professor John Kirby
Understanding the mechanisms underpinning treatment non-response in Primary Biliary Cirrhosis: a tool for treatment stratification2014
Achilleas FLOUDAS
Dr Laura Jopson
Dacia Jones
Dr Andrew Knight
Dr Jeremy Palmer
et al.
Altered B cell populations and cytokine production in primary biliary cirrhosis2013
Greta Pells
Samantha Ducker
Dr Jeremy Palmer
Emerita Professor Julia Newton
Dacia Jones
et al.
Patient Impact of Inflammation in Primary Biliary Cirrhosis (PBC): Inflammatory Cytokine Levels are Elevated but Unrelated to Fatigue Severity2013
Dr Jeremy Palmer
Professor Farhad Kamali
Quality of bevacizumab compounded for intravitreal administration2013
Dr Graeme O'Boyle
Christopher Fox
Dr Hannah Walden
Dr Joe Willet
Dr Emily Mavin
et al.
Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation2012
Dr Jeremy Palmer
Dr Andrew Knight
Professor Kevin Marchbank
A novel chimeric antigen hC3d-TTCF-hC4BP interacts with mCR2 allowing extensive testing as a novel adjuvant using murine models2010
Dr Stuart Kendrick
Dr Graeme O'Boyle
Professor Jelena Mann
Dr Mujdat Zeybel
Dr Jeremy Palmer
et al.
Acetate, the Key Modulator of Inflammatory Responses in Acute Alcoholic Hepatitis2010
Dr Jeremy Palmer
Dr Imran Patanwala
Elsbeth Henderson
Professor Chris Day
Professor David Jones
et al.
Allo- and auto-antibody responses in ALD as biomarkers of prognosis2010
Dr Stuart Kendrick
Elsbeth Henderson
Dr Jeremy Palmer
Professor David Jones
Professor Chris Day
et al.
Theophylline improves steroid sensitivity in acute alcoholic hepatitis2010
Dr Jeremy Palmer
Dr Hannah Walden
Emeritus Professor John Kirby
Professor David Jones
680: Incorporation of 6-bromohexanoic acid (6BH) into cellular pyruvate dehydrogenase complex (PDC): Further evidence for generation of an autoimmunogenic neoantigen in primary billary cirrhosis (PBC)2009
Dr Stuart Kendrick
Dr Graeme O'Boyle
Dr Jeremy Palmer
Professor David Jones
Enhanced inflammatory responses in alcoholic liver disease: is acetate the key?2008
Dr Jeremy Palmer
Professor David Jones
Emeritus Professor John Kirby
Human Th17 cells: investigation of T cell differentiation in the presence of TGF-beta and a range of pro-inflammatory cytokines2008
Emerita Professor Julia Newton
Dr Kieren Hollingsworth
Dr Jeremy Palmer
Professor Roy Taylor
Professor Andrew Blamire
et al.
Mitochondrial dysfunction and muscle PH abnormality post-exercise: A two-hit mechanism for fatigue pathogenesis in primary biliary cirrhosis2008
Dr Kieren Hollingsworth
Emerita Professor Julia Newton
Professor Roy Taylor
Dr Claire McDonald
Dr Jeremy Palmer
et al.
Pilot Study of Peripheral Muscle Function in Primary Biliary Cirrhosis: Potential Implications for Fatigue Pathogenesis2008
Professor David Jones
Dr Jeremy Palmer
Professor Alastair Burt
Emeritus Professor John Kirby
The specificity of liver inflammation in mouse models of primary biliary cirrhosis2008
Dr Hannah Walden
Emeritus Professor John Kirby
Emeritus Professor Steve Yeaman
Dr Joseph Gray
Professor David Jones
et al.
Xenobiotic Incorporation into Pyruvate Dehydrogenase Complex Can Occur Via the Exogenous Lipoylation Pathway2008
Dr Stuart Kendrick
Dr Jeremy Palmer
Professor David Jones
Professor Chris Day
Lymphocyte steroid sensitivity in severe alcoholic hepatitis2007
Dr Hannah Walden
Dr Jeremy Palmer
Emeritus Professor John Kirby
Dr Stuart Kendrick
Professor David Jones
et al.
Substrate promiscuity in the pyruvate dehydrogenase complex (PDC) lipoylation pathway: Xenobiotic incorporation as a potential mechanism for the pathogenesis of primary biliary cirrhosis (PBC)2007
Professor David Jones
Dr Amanda Robe
Dr Jeremy Palmer
Emeritus Professor John Kirby
Adoptive transfer of self-PDC reactive T-cells into naive mice induces portal tract and bile duct changes characteristic of primary biliary cirrhosis (PBC)2006
Dr Amanda Greenall
Katherine Martin
Dr Jeremy Palmer
Dr Joseph Gray
Dr Simon Whitehall
et al.
Hip3 interacts with the HIRA proteins Hip1 and Slm9 and is required for transcriptional silencing and accurate chromosome segregation2006
Anna McHugh
Dr Amanda Robe
Dr Jeremy Palmer
Professor David Jones
PDC-E3BP is not a dominant T-cell autoantigen in primary biliary cirrhosis2006
Dr Amanda Robe
Emeritus Professor John Kirby
Professor David Jones
Dr Jeremy Palmer
A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse2005
Dr Amanda Robe
Emeritus Professor John Kirby
Professor David Jones
Dr Jeremy Palmer
A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse2005
Dr Jeremy Palmer
Emeritus Professor John Kirby
Professor David Jones
Apoptosis as a mechanism for cell surface expression of the autoantigen pyruvate dehydrogenase complex2004
Dr Amanda Robe
Dr Jeremy Palmer
Emeritus Professor John Kirby
Professor David Jones
Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process2004
Dr Amanda Robe
Dr Jeremy Palmer
Emeritus Professor John Kirby
Professor David Jones
Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process2004
Dr Jeremy Palmer
Dr Amanda Robe
Professor Alastair Burt
Emeritus Professor John Kirby
Professor David Jones
et al.
Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse2004
Anna McHugh
Dr Jeremy Palmer
Emeritus Professor Steve Yeaman
Professor David Jones
Is PDC-E3BP (protein X) a T-cell autoantigen in primary biliary cirrhosis?2003
Dr Amanda Robe
Dr Jeremy Palmer
Emeritus Professor John Kirby
Professor Margaret Bassendine
Professor David Jones
et al.
[abstract] Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC)2002
Professor David Jones
Dr Jeremy Palmer
Professor Alastair Burt
Dr Amanda Robe
Emeritus Professor John Kirby
et al.
Bacterial motif DNA as an adjuvant for the breakdown of immune self-tolerance to pyruvate dehydrogenase complex2002
Dr Jeremy Palmer
Emeritus Professor John Kirby
Professor David Jones
Breakdown of tolerance is seen to both PDC-E2 and PDC-E3BP, individual antigens in primary biliary cirrhosis, in a mouse model of PDC autoreactivity2002
Dr Amanda Robe
Dr Jeremy Palmer
Emeritus Professor John Kirby
Professor David Jones
Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC)2002
Professor David Jones
Dr Jeremy Palmer
Dr Amanda Robe
Emeritus Professor John Kirby
Oral tolerisation to pyruvate dehydrogenase complex as a potential therapy for primary biliary cirrhosis2002
Dr Jeremy Palmer
Emeritus Professor John Kirby
Professor David Jones
The immunology of primary biliary cirrhosis: The end of the beginning?2002
Dr Jeremy Palmer
Emeritus Professor Steve Yeaman
Professor David Jones
Epitope specificity of anti-PDC E1 alpha antibodies in primary biliary cirrhosis (PBC)2001
Dr Jeremy Palmer
Emeritus Professor John Kirby
Emeritus Professor Steve Yeaman
Professor Margaret Bassendine
Professor David Jones
et al.
Secretory autoantibodies in primary biliary cirrhosis (PBC)2000
Dr Jeremy Palmer
Professor David Jones
Professor Janet Quinn
Anna McHugh
Emeritus Professor Steve Yeaman
et al.
Characterization of the autoantibody responses to recombinant E3 binding protein (protein X) of pyruvate dehydrogenase in primary biliary cirrhosis1999
Marian Case
Professor Alastair Burt
Joan Hughes
Dr Jeremy Palmer
Professor Margaret Bassendine
et al.
Erratum to 'Enhanced ultrasensitive detection of structurally diverse antigens using a single immuno-PCR assay protocol' (Journal of Immunological Methods (1999) 223 (93-106))1999
Dr Jeremy Palmer
Emeritus Professor John Kirby
Emeritus Professor Steve Yeaman
Professor David Jones
Persistence of secretory autoantibodies in PBC patients post-liver transplant: a potential mechanism for disease recurrence?1999
Dr Jeremy Palmer
Emeritus Professor Steve Yeaman
Professor Margaret Bassendine
Professor David Jones
T cell responses to the putative dominant autoepitope in primary biliary cirrhosis (PBC)1999
Dr Ian Brotherick
Dr Brian Shenton
Emeritus Professor John Kirby
Dr Jeremy Palmer
Emeritus Professor Steve Yeaman
et al.

Production of immunosuppressive factors by a cultured tumor cell line and their effect on lymphocyte proliferation and cells cycle response

1993