Publications by Professor Peter Blain - ePrints

Browsing publications by Professor Peter Blain.

Newcastle Authors	Title	Year
Professor Peter Blain	Neurotoxicology: A clinical systems-based review	2024
Professor Peter Blain	Chemical, biological, radiological, and nuclear mass casualty medicine: a review of lessons from the Salisbury and Amesbury Novichok nerve agent incidents	2022
Dr Alistair Leitch Dr Ibrahim Ibrahim Dr Tarek Mamdouh Abdelghany Dr Alex Charlton Clair Roper et al.	The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver	2021
Dr Tarek Mamdouh Abdelghany Dr Alistair Leitch Professor Peter Blain Professor Matt Wright	Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids	2020
Professor Peter Blain	Chemical terrorism	2020
Dr Michael Dunn Dr Robert Jefferson Professor Peter Blain Professor Simon Thomas	Modest and variable efficacy of pre-exposure hydroxocobalamin and dicobalt edetate in a porcine model of acute cyanide salt poisoning	2020
Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Alex Charlton Professor Fiona Oakley Dr Lee Borthwick et al.	Renal injury and hepatic effects from the methylimidazolium ionic liquid M8OI in mouse	2020
Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Phillip Probert Dr Stephanie Meyer Dr Jeremy Palmer et al.	The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects	2020
Professor Peter Blain	Threat potential of pharmaceutical based agents	2020
Dr Stephanie Meyer Dr Michael Dunn Dr Daniel Vidler Professor Peter Blain Dr Paul Jowsey et al.	Phosphorylation of MCPH1 isoforms during mitosis followed by isoform-specific degradation by APC/C-CDH1	2019
Dr Paul Keane Dr Peter Hanson Lina Patterson Professor Peter Blain Philippa Hepplewhite et al.	Trichloroethylene and its metabolite TaClo lead to degeneration of substantia nigra dopaminergic neurones: Effects in wild type and human A30P mutant α-synuclein mice	2019
Dr Shahriar Khateri Professor Mahdi Balali-Mood Professor Peter Blain Emeritus Professor Faith Williams Dr Paul Jowsey et al.	DNA damage and repair proteins in cellular response to sulfur mustard in Iranian veterans more than two decades after exposure	2018
Dr Ann Fitchett Professor Peter Blain Dr Christopher Morris Dr Sarah Judge	Gene expression analysis reveals chronic low level exposure to the pesticide diazinon affects Psychological Disorders gene sets in the adult rat	2018
Dr Phillip Probert Dr Alistair Leitch Dr Michael Dunn Dr Stephanie Meyer Dr Jeremy Palmer et al.	Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis	2018
Rizwan Nisar Dr Peter Hanson Dr Paul Keane Dr Langping He Professor Robert Taylor et al.	Manganese-Containing Thiocarbamates Cause Free Radical Production and Caspase-Independent Cell Death following Mitochondrial Dysfunction in Neural Cells	2018
Professor Peter Blain Dr Paul Jowsey Dr Shahriar Khateri Professor Mahdi Balali-Mood	Telomere shortening associated with increased levels of oxidative stress in sulfur mustard-exposed Iranian veterans	2018
Dr Alistair Leitch Anne Lakey will Hotham Professor Loranne Agius Professor George Kass et al.	The ionic liquid 1-octyl-3-methylimidazolium (M8OI) is an activator of the human estrogen receptor alpha	2018
Dr Stephanie Meyer Dr Phillip Probert Anne Lakey Dr Alistair Leitch Dr Lynsay Blake et al.	Environmental xenoestrogens super-activate a variant murine ER beta in cholangiocytes	2017
Dr Stephanie Meyer Dr Phillip Probert Anne Lakey Andrew Axon Dr Alistair Leitch et al.	Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse	2017
Dr Ahmad Khundakar Dr Peter Hanson Dr Daniel Erskine Dr Nichola Lax Evangelia Karyka et al.	Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations	2016
Dr Simon Hill Dr Michael Dunn Professor Peter Blain Professor Simon Thomas	Clinical toxicity following analytically confirmed use of the synthetic cannabinoid receptor agonist MDMB-CHMICA. A report from the Identification Of Novel psychoActive substances (IONA) study	2016
Professor Peter Blain Dr Paul Jowsey	Fe65 is Phosphorylated on Ser²⁸⁹after UV-Induced DNA Damage	2016
Dr Sarah Judge Claire Savy Dr Madeline Campbell Rebecca Dodds Grace Laws et al.	Mechanism for the acute effects of organophosphate pesticides on the adult 5-HT system	2016
Dr Peter Hanson Professor Peter Blain Dr Christopher Morris	Neurotoxicity of novel psychoactive substances	2016
Dr Phillip Probert Dr Stephanie Meyer Fouzeyyah Alsaeedi Andrew Axon Dr Emma Fairhall et al.	An expandable donor-free supply of functional hepatocytes for toxicology	2015
Dr Paul Jowsey Professor Peter Blain	Checkpoint kinase 1 is activated and promotes cell survival after exposure to sulphur mustard	2015
Rizwan Nisar Dr Peter Hanson Dr Langping He Professor Robert Taylor Professor Peter Blain et al.	Diquat causes caspase-independent cell death in SH-SY₅Y cells by production of ROS independently of mitochondria	2015
Claire Savy Dr Ann Fitchett Professor Richard McQuade Dr Sasha Gartside Dr Christopher Morris et al.	Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour	2015
Professor Peter Blain	Mass casualty decontamination in a chemical or radiological/nuclear incident with external contamination: Guiding principles and research needs	2015
Dr Simon Hill Professor Simon Thomas Emeritus Professor Paul Flecknell Dr Aurelie Thomas Dr Christopher Morris et al.	Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes	2015
Aimen Amer Dr Phillip Probert Dr Michael Dunn Margaret Knight Dr Abigail Vallance et al.	Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation	2015
Dr Christopher Morris Claire Savy Dr Sarah Judge Professor Peter Blain	Acute toxicity of organophosphorus compounds	2014
Dr Paul Jowsey Professor Peter Blain	Fe65 Ser²²⁸ is Phosphorylated by ATM/ATR and Inhibits Fe65-APP-Mediated Gene Transcription	2014
Dr John Skamarauskas Professor Fiona Oakley Dr Fiona Smith Carlo Bawn Dr Michael Dunn et al.	Non-invasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker	2014
Craig Moore Dr Simon Wilkinson Professor Peter Blain Dr Michael Dunn Dr Gillian Aust et al.	Percutaneous absorption and distribution of organophosphates (chlorpyrifos and dichlorvos) following dermal exposure and decontamination scenarios using in vitro human skin model	2014
Dr Stephanie Meyer Andrew Axon Dr Paul Jowsey Emeritus Professor Faith Williams Professor Peter Blain et al.	Tartrazine is not an activator of the mouse oestrogen ER alpha and ER beta receptors	2014
Dr Simon Wilkinson Professor Peter Blain Professor Faith Williams	Use of a human skin in vitro model to investigate the influence of 'every-day' clothing and skin surface decontamination on the percutaneous penetration of organophosphates	2014
Dr Paul Jowsey Professor Peter Blain	Whole Genome Expression Analysis in Primary Bronchial Epithelial Cells after Exposure to Sulphur Mustard	2014
Professor Peter Blain	A screening tool to prioritize public health risk associated with accidental or deliberate release of chemicals into the atmosphere	2013
Raghu Sidaginamale Professor Tom Joyce James Lord Dr Robert Jefferson Professor Peter Blain et al.	Blood metal ion testing is an effective screening tool to identify poorly performing metal on metal bearing surfaces	2013
Dr Shahriar Khateri Dr Paul Jowsey Professor Peter Blain Professor Mahdi Balali-Mood	Deoxyribonucleic acid damage in Iranian veterans 25 years after wartime exposure to sulfur mustard	2013
Dr Simon Hill Dr Michael Dunn Professor Peter Blain Professor Simon Thomas	Severe clinical toxicity associated with analytically confirmed recreational use of 25I–NBOMe: case series	2013
Andrew Baron Professor Stephen Rushton Dr Christopher Morris Professor Peter Blain Dr Sarah Judge et al.	Sex differences in effects of low level domoic acid exposure	2013
Professor Tom Joyce Professor Peter Blain Dr Robert Jefferson	The clinical implications of elevated blood metal ion concentrations in asymptomatic patients with MoM hip resurfacings: a cohort study	2013
Professor Peter Blain	Biotoxins and Bioterrorism: Ricin and Saxitoxin	2012
Dr Peter Hanson Professor Peter Blain Dr Christopher Morris	Brominated flame retardants - Neurotoxic to humans?	2012
Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	DNA damage responses in cells exposed to sulphur mustard	2012
Dr Marzena Kurzawa-Akanbi Dr Peter Hanson Professor Peter Blain Debbie Lett Professor Ian McKeith et al.	Glucocerebrosidase Mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease	2012
Professor Simon Thomas Dr Robert Jefferson Dr Michael Dunn Dr Daniel Vidler Professor Peter Blain et al.	Rapid and complete bioavailability of antidotes for organophosphorus nerve agent and cyanide poisoning in minipigs after intraosseous administration	2012
Andrew Axon Dr Felicity May Dr Luke Gaughan Professor Faith Williams Professor Peter Blain et al.	Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity	2012
Paul Keane Dr Sarah Judge Professor Peter Blain Dr Christopher Morris	An investigation into the mechanism of trichloroethylene neurotoxicity in relation to Parkinsonism	2011
Claire Savy Dr Christopher Morris Professor Peter Blain Dr Sarah Judge	Behavioural effects of low level exposure to organophosphate pesticides	2011
Paul Keane Dr Marzena Kurzawa-Akanbi Professor Peter Blain Dr Christopher Morris	Mitochondrial dysfunction in Parkinson's Disease	2011
Andrew Baron Rachel Steeg Dr Christopher Morris Professor Peter Blain Dr Sarah Judge et al.	Motor activity is a sensitive behavioural biomarker of low level exposure to the shellfish toxin, domoic acid, in male and female rats	2011
Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	The role of homologous recombination in the cellular response to sulphur mustard	2011
Andy Axon Dr David Cowie Professor Fiona Oakley Professor Faith Williams Professor Peter Blain et al.	Acute oestradiol (E2) administration to mice results in liver portal tract inflammation	2010
Professor Peter Blain Dr Robert Jefferson	Occupational Toxicology: general principles	2010
Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	The role of homologous recombination in the cellular response to sulphur mustard	2010
Dr Robert Jefferson Professor Peter Blain Professor Simon Thomas	Diagnosis and treatment of polonium poisoning Polonium poisoning	2009
Professor Peter Blain Dr Robert Jefferson Professor Simon Thomas	Did he really bring the war home with him?	2009
Dr Kathryn Atherton Professor Faith Williams Professor Stephen Rushton Professor Peter Blain Dr Elaine Mutch et al.	DNA damage in horticultural farmers: a pilot study showing an association with organophosphate pesticide exposure	2009
Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	DNA damage, signalling and repair after exposure of cells to the sulphur mustard analogue 2-chloroethyl ethyl sulphide	2009
Seth Remington Dr Paul Jowsey Professor Faith Williams Professor Peter Blain	Investigations into the genotoxic potential of dichlorvos	2008
Dr Elaine Mutch Professor Peter Blain Professor Faith Williams	A possible mechanism for the neurotoxicity of trichloroethylene to man	2007
Ria Wilkinson Dr Christopher Jewell Dr Simon Wilkinson Professor Faith Williams Professor Peter Blain et al.	The effect of in vitro receptor media choice on the percutaneous absorption of methyl paraben	2007
Professor Peter Blain	Clinical management of casualties exposed to lung damaging agents: a critical review	2006
Zhen Jiang Dr Elaine Mutch Professor Peter Blain Professor Faith Williams	Conversion of trichloroethylene to chloral using occupationally relevant levels	2006
Professor Peter Blain	Supplement to HOSDB Evaluations of Taser Devices: A collection of medical evidence and other source material	2006
Dr Ovnair Sepai Adem BEM Professor Faith Williams David Henderson Professor Peter Blain	Biological monitoring of exposure to organochlorine pesticides in an African population	2005
Vanessa Gage Professor Peter Blain Julian Leathart Professor Ann Daly Professor Faith Williams et al.	Association of DNA damage to human peripheral lymphocytes with age and MnSOD and OGG1 genotype	2004
Vanessa Gage Professor Peter Blain Dr Elaine Mutch Professor Faith Williams	DNA damage and 8-hydroxy-2 '-deoxyguanosine formation due to hydrogen peroxide exposure in HepG2 cells	2004
Professor Peter Blain	Guidance on a strategy for the risk assessment of chemical carcinogens	2004
Emeritus Professor John Harris Professor Peter Blain	Neurotoxicology: What the neurologist needs to know	2004
Emeritus Professor John Harris Professor Peter Blain	Neurotoxicology: What the neurologist needs to know	2004
Professor Peter Blain	Report of a Royal Society Group: Making the UK safer: detecting and decontaminating chemical and biological agents	2004
Professor Peter Blain	Committee on carcinogenicity of chemicals in food, consumer products and the environment - Statement on ILSI/HESI research programme on alternative cancer models.	2003
Dr Elaine Mutch Professor Ann Daly Julian Leathart Professor Peter Blain Professor Faith Williams et al.	Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man?	2003
Professor Peter Blain	Tear gases and irritant incapacitants: 1-Chloroacetophene, 2-Chlorobenzylidene malononitrile and dibenz[B,F]-1,4-oxazepine	2003
Professor Peter Blain	Treatment of poisoning by selected chemical compounds	2003
Professor Tanja Pless-Mulloli Professor Peter Blain	Environmental Hazards and Health: A Scoping Study	2002
Professor Peter Blain	Adverse health effects after low level exposure to organophosphates	2001
Professor Peter Blain	Assessing “Sun Know How”: comparing outdoor and indoor workers.	2001
Professor Peter Blain	Genomics: Some Implications for Defence	2001
Professor Peter Blain	The Role of the Defence Scientific Advisory Council	2001
Denise Howel Professor Stephen O'Brien Dr David Chinn Professor Peter Blain	Upper aerodigestive tract cancers in former employees at an iron and steel works	2001
Dr Elaine Mutch Professor Faith Williams Professor Peter Blain	Cytogenetic response without changes in peripheral cholinesterase enzymes following exposure to a sheep dip containing diazinon in vivo and in vitro	2000
Dr Gail de Blaquiere Louise Waters Professor Peter Blain Professor Faith Williams	Electrophysiological and biochemical effects of single and multiple doses of the organophosphate diazinon in the mouse	2000
Professor Peter Blain	The Environmental Aspects of Dialysis	2000
Dr Elaine Mutch Professor Peter Blain Professor Faith Williams	The role of metabolism in determining susceptibility to parathion toxicity in man	1999
Professor Peter Blain	Occupational asthma due to porcine pancreatic amylase	1998
Professor Peter Blain Professor Faith Williams	The percutaneous absorption and skin distribution of lindane in man. II. In vitro studies	1997
Professor Peter Blain Professor Faith Williams	The effect of sulphur mustard on glutathione levels in rat lung slices and the influence of treatment with arylthiols and cysteine esters	1996
Dr Elaine Mutch Professor Peter Blain Professor Faith Williams	Interindividual variations in enzymes controlling organophosphate toxicity in man	1992