Publications by Dr Laurent Rigoreau - ePrints

Browsing publications by Dr Laurent Rigoreau.

Newcastle Authors	Title	Year
Stephanie Myers Duncan Miller Dr Lauren Molyneux Dr Mercedeh Arasta Dr Ruth Bawn et al.	Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4	2019
Stephanie Myers Dr Ruth Bawn Betty Cottyn Dr Lauren Molyneux Dr Celine Cano et al.	High-throughput screening and hit validation of extracellular-related kinase 5 (ERK5) inhibitors	2016
Tristan Reuillon Duncan Miller Stephanie Myers Dr Lauren Molyneux Dr Celine Cano et al.	Pyrrolcarboxamide Derivatives for the Inhibition of ERK5	2016
Dr Ruth Bawn Tristan Reuillon Emeritus Professor Bernard Golding Professor Roger Griffin Dr Ian Hardcastle et al.	Development of extracellular signal-regulated kinase 5 (ERK5) inhibitors for anti-cancer therapy	2014
Dr Kappusamy Saravanan Dr Celine Cano Professor Nicola Curtin Emeritus Professor Bernard Golding Dr Karen Haggerty et al.	Identification of potent water-soluble DNA-dependent protein kinase (DNA-PK) inhibitors using a small-molecule library approach [abstract]	2008
Michael Batey Dr Laurent Rigoreau Professor Roger Griffin Professor Herbie Newell Professor Nicola Curtin et al.	Potent in vitro and in vivo radiosensitisation by the selective DNA-dependent protein kinase inhibitor KU-0060648 [abstract]	2008
Jonathan Hollick Dr Laurent Rigoreau Dr Celine Cano Professor Nicola Curtin Emeritus Professor Bernard Golding et al.	Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase	2007
Dr Ian Hardcastle Professor Nicola Curtin Justin John James Leahy Martin Stockley Emeritus Professor Bernard Golding et al.	Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach	2005
Professor Roger Griffin Emeritus Professor Bernard Golding Sophie Guiard Dr Ian Hardcastle Justin John James Leahy et al.	Selective benzopyranone and pyrimido[2,1-alpha]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: Synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro	2005
Justin John James Leahy Emeritus Professor Bernard Golding Professor Roger Griffin Dr Ian Hardcastle Dr Laurent Rigoreau et al.	Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries	2004
Jonathan Hollick Emeritus Professor Bernard Golding Dr Ian Hardcastle Dr Laurent Rigoreau Professor Roger Griffin et al.	2,6-disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-dependent protein kinase (DNA-PK)	2003
Jonathan Hollick Emeritus Professor Bernard Golding Professor Roger Griffin Dr Ian Hardcastle Justin John James Leahy et al.	Application of combinatorial chemistry for the identification of pyran-4-one and thiopyran-4-one inhibitors of DNA-dependent protein kinase	2002
Professor Roger Griffin Dr Ian Hardcastle Dr Laurent Rigoreau Martin Stockley Justin John James Leahy et al.	Cassette dosing iv and ip of novel DNA dependent protein kinase inhibitors	2002
Professor Roger Griffin Dr Ian Hardcastle Dr Laurent Rigoreau Martin Stockley Justin John James Leahy et al.	High throughput pharmacokinetics of novel DNA-dependent protein kinase inhibitors	2002
Dr Stephany Veuger Professor barbara Durkacz Emeritus Professor Bernard Golding Professor Roger Griffin Professor Herbie Newell et al.	Radiosensitization by novel inhibitors of PARP, PI, and DNA-PK, NU7026, in vitro	2001
Martin Stockley Professor William Clegg Emeritus Professor Bernard Golding Nicola Martin Dr Laurent Rigoreau et al.	Synthesis, crystal structure determination, and biological properties of the DNA-dependent protein kinase (DNA-PK) inhibitor 3-cyano-6-hydrazonomethyl-5-(4-pyridyl)pyrid-[1H]-2-one (OK-1035)	2001