Sema Ejder Dr Jon Marles-Wright Professor Rick Lewis
| Molecular insights into intra-complex signal transmission during stressosome activation | 2022 |
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Dr Sven Halbedel Professor Rick Lewis
| Structural basis for interaction of DivIVA/GpsB proteins with their ligands | 2019 |
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Simon Booth Professor Rick Lewis
| Structural basis for the coordination of cell division with the synthesis of the bacterial cell envelope | 2019 |
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Dr Arnaud Basle Dr Lorraine Hewitt Dr Alan Koh Dr Heather Lamb Paul Thompson et al. | Crystal structure of NucB, a biofilm-degrading endonuclease | 2018 |
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Jan Kampf Kerstin Kruse Dr Robert Cleverley Professor Rick Lewis
| Selective Pressure for Biofilm Formation in Bacillus subtilis: Differential Effect of Mutations in the Master Regulator SinR on Bistability | 2018 |
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Dr Robert Cleverley Zoe Rutter Federico Corona Dr Richard Daniel Dr Sven Halbedel et al. | The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes | 2018 |
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Professor Rick Lewis
| The hidden lipoproteome of Staphylococcus aureus | 2018 |
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Dr Alexander Egan Dr Robert Cleverley Dr Katharina Pazos Don Pedro Professor Rick Lewis Professor Waldemar Vollmer et al. | Regulation of bacterial cell wall growth. | 2017 |
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Professor Rick Lewis Dr Jon Marles-Wright
| Structure and Function of the Stressosome Signalling Hub | 2017 |
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Professor Rick Lewis
| The GpsB files: The truth is out there | 2017 |
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Dr Agata Rozanska Dr Joanna Rorbach Dr Fei Gao Professor Rick Lewis Professor Zofia Chrzanowska-Lightowlers et al. | The human RNA-binding protein RBFA promotes the maturation of the mitochondrial ribosome | 2017 |
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Dr Robert Cleverley Harriet Lane Professor Rick Lewis Dr Sven Halbedel
| Structure of the bacterial cell division determinant GpsB and its interaction with penicillin-binding proteins | 2016 |
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Dr Robert Cleverley Dr Alexander Egan Professor Waldemar Vollmer Dr Sven Halbedel Professor Rick Lewis et al. | Subunit arrangement in GpsB a regulator of cell wall biosynthesis | 2016 |
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Professor Robin Harris Professor Rick Lewis
| The collagen type I segment long spacing (SLS) and fibrillar forms: Formation by ATP and sulphonated diazo dyes | 2016 |
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Dr Katharina Pazos Don Pedro Dr Vincent Rao Dr Jacob Biboy Dr Daniela Vollmer Professor Rick Lewis et al. | The redundancy of peptidoglycan carboxypeptidases ensures robust cell shape maintenance in Escherichia coli | 2016 |
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William Wilson Dr Hue Hornig - Do Dr Francesco Bruni Professor Rick Lewis Dr Lorraine Hewitt et al. | A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression | 2014 |
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Dr Lorraine Hewitt Professor Rick Lewis
| Control of the Diadenylate Cyclase CdaS in Bacillus subtilis: An Autoinhibitory Domain Limits c-di-AMP Production | 2014 |
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Dr Ulrike Mader Wenke Reiss Professor Rick Lewis
| Deletion of membrane-associated Asp23 leads to upregulation of cell wall stress genes in Staphylococcus aureus | 2014 |
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Dr Alexander Egan Professor Rick Lewis Professor Waldemar Vollmer
| Elongated structure of the outer-membrane activator of peptidoglycan synthesis LpoA: Implication for PBP1A stimulation. | 2014 |
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Dr Katarzyna Mickiewicz Frances Davison Professor Rick Lewis Professor Colin Brooks
| Mutagenesis of Ly49B Reveals Key Structural Elements Required for Promiscuous Binding to MHC Class I Molecules and New Insights into the Molecular Evolution of Ly49s | 2014 |
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Dr Arnaud Basle Professor Rick Lewis
| Some of the most interesting CASP11 targets through the eyes of their authors | 2014 |
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Dr Robert Cleverley Dr Arnaud Basle Dr Nhat Khai Bui Dr Lorraine Hewitt Dr Alexandra Solovyova et al. | Structure and function of a spectrin-like regulator of bacterial cytokinesis | 2014 |
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Christopher Hoyland Christine Aldridge Dr Robert Cleverley Marie-Clemence Duchene Karzan Sidiq et al. | Structure of the LdcB LD-carboxypeptidase reveals the molecular basis of peptidoglycan recognition | 2014 |
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Dr Joseph Newman Dr Cecilia Rodrigues Professor Rick Lewis
| The YmdB Phosphodiesterase Is a Global Regulator of Late Adaptive Responses in Bacillus subtilis | 2014 |
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Professor Robin Harris Dr Andrei Soliakov Professor Rick Lewis
| In vitro fibrillogenesis of collagen type I in varying ionic and pH conditions | 2013 |
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Professor Rick Lewis
| Exploring the role of SlrR and SlrA in the SinR epigenetic switch | 2013 |
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Dr Joseph Newman Dr Cecilia Rodrigues Professor Rick Lewis
| Molecular Basis of the Activity of SinR Protein, the Master Regulator of Biofilm Formation in Bacillus subtilis | 2013 |
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Professor Rick Lewis
| Simulations of stressosome activation emphasize allosteric interactions between RsbR and RsbT | 2013 |
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Professor Robin Harris Dr Andrei Soliakov Professor Rick Lewis Professor Jeremy Lakey
| Alhydrogel® adjuvant, ultrasonic dispersion and protein binding: A TEM and analytical study | 2012 |
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Alice Eberhardt Christopher Hoyland Dr Daniela Vollmer Stephanie Bisle Dr Robert Cleverley et al. | Attachment of capsular polysaccharide to the cell wall in Streptococcus pneumoniae | 2012 |
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Dr Lorraine Hewitt Dr Cecilia Rodrigues Dr Alexandra Solovyova Professor Colin Harwood Professor Rick Lewis et al. | Dissection of the network of interactions that links RNA processing with glycolysis in the Bacillus subtilis degradosome | 2012 |
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Dr Artur Rogowski Dr Adam Jackson Professor Rick Lewis Emeritus Professor Harry Gilbert Dr Jon Marles-Wright et al. | Introducing endo-xylanase activity into an exo-acting arabinofuranosidase that targets side chains | 2012 |
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Dr Elise Glen Dr Ana Topf Dr Darroch Hall Dr John O'Sullivan Linda Sneddon et al. | Nonsynonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation | 2012 |
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Professor Rick Lewis Dr Ulrike Mader
| RNA degradation in Bacillus subtilis: an interplay of essential endo- and exoribonucleases | 2012 |
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Helen Pagett Dr Jon Marles-Wright Professor Rick Lewis Professor Robin Harris Dr Gary Caldwell et al. | Structural characterisation of the N-glycan moiety of the barnacle settlement-inducing protein complex (SIPC) | 2012 |
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Alex Faulds-Pain Professor Rick Lewis Dr Jon Marles-Wright
| Structural insight into the Clostridium difficile ethanolamine utilisation microcompartment | 2012 |
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Dr John Berrisford Dr Arnaud Basle Professor Rick Lewis Dr Jon Marles-Wright
| The Bacterial Stressosome: A Modular System that Has Been Adapted to Control Secondary Messenger Signaling | 2012 |
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Charles Debieux Elizabeth Dridge Professor Rick Lewis Dr Clive Butler
| A bacterial process for selenium nanosphere assembly | 2011 |
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Cedric Montanier Dr James Flint Dr Arnaud Basle Professor Rick Lewis Emeritus Professor Harry Gilbert et al. | A novel, noncatalytic carbohydrate-binding module displays specificity for galactose-containing polysaccharides through calcium-mediated oligomerization | 2011 |
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Dr Yoshikazu Kawai Dr Jon Marles-Wright Dr Robert Cleverley Dr Robyn Emmins Nadja Heinz et al. | A widespread family of bacterial cell wall assembly proteins | 2011 |
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Professor Robin Harris Professor Rick Lewis
| Cholesterol microcrystals and cochleate cylinders: Attachment of pyolysin oligomers and domain 4 | 2011 |
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Dr Fiona Cuskin Dr Alexandra Solovyova Professor Rick Lewis Professor Paul Race
| Crystallization and preliminary X-ray analysis of the bacillaene synthase trans-acting acyltransferase PksC | 2011 |
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Dr Elise Glen Dr Ana Topf Dr Darroch Hall Dr John O'Sullivan Linda Sneddon et al. | Non-synonymous SMAD6 mutations impaired inhibition of BMP signalling in patients with congenital cardiovascular malformation | 2011 |
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Dr Joseph Newman Professor Rick Lewis
| RNase Y in Bacillus subtilis: a Natively Disordered Protein That Is the Functional Equivalent of RNase E from Escherichia coli | 2011 |
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Professor Rick Lewis Emeritus Professor Harry Gilbert
| Structure and Function of an Arabinoxylan-specific Xylanase | 2011 |
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Alan Cartmell Lauren McKee Professor Rick Lewis Emeritus Professor Harry Gilbert Dr Jon Marles-Wright et al. | The Structure and Function of an Arabinan-specific α-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases | 2011 |
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Dr Jon Marles-Wright Professor Rick Lewis
| The structure of a D-lyxose isomerase from the sigma(B) regulon of Bacillus subtilis | 2011 |
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Dr Lorraine Hewitt Dr Cecilia Rodrigues Dr Alexandra Solovyova Professor Colin Harwood Professor Rick Lewis et al. | Unusual, dual endo- and exonuclease activity in the degradosome explained by crystal structure analysis of RNaseJ1 | 2011 |
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Dr Cecilia Rodrigues Dr Lorraine Hewitt Professor Rick Lewis
| Functional Dissection of a Trigger Enzyme: Mutations of the Bacillus subtilis Glutamate Dehydrogenase RocG That Affect Differentially Its Catalytic Activity and Regulatory Properties | 2010 |
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Dr Elisabeth Lowe Elizabeth Dridge Charles Debieux Dr Ian Singleton Professor Rick Lewis et al. | Quinol-cytochrome c Oxidoreductase and Cytochrome c4 Mediate Electron Transfer during Selenate Respiration in Thauera selenatis | 2010 |
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Dr Jon Marles-Wright Professor Rick Lewis
| The stressosome: molecular architecture of a signalling hub | 2010 |
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Professor Rick Lewis
| Characterization of the Sporulation Initiation Pathway of Clostridium difficile and Its Role in Toxin Production | 2009 |
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Kathrin Schirner Dr Jon Marles-Wright Professor Rick Lewis Professor Jeff Errington
| Distinct and essential morphogenic functions for wall- and lipo-teichoic acids in Bacillus subtilis | 2009 |
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Dr Claire Dumon Dr James Flint Dr Susan Firbank Professor Rick Lewis Emeritus Professor Harry Gilbert et al. | Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function | 2009 |
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Dr Kaveh Emami Dr Topakas Topakas Tibor Nagy Joanna Henshaw Dr Kelly Jackson et al. | Regulation of the xylan-degrading apparatus of Cellvibrio japonicus by a novel two-component system | 2009 |
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Steven Hardwick Professor Rick Lewis
| Role of RsbU in controlling SigB activity in Staphylococcus aureus following alkaline stress | 2009 |
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Dr Jon Marles-Wright Professor Rick Lewis Professor Waldemar Vollmer
| Synthesis of CDP-activated ribitol for teichoic acid precursors in Streptococcus pneumoniae | 2009 |
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Dr Jon Marles-Wright Professor Rick Lewis
| The structure of bacterial RNA polymerase in complex with the essential transcription elongation factor NusA | 2009 |
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Dr Joseph Newman Professor Rick Lewis Emeritus Professor Harry Gilbert Dr James Flint
| Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides insights into the mechanism of substrate recognition | 2008 |
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Dr Claire Dumon Dr James Flint Professor Rick Lewis Professor Jeremy Lakey Carl Morland et al. | Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure | 2008 |
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Dr Jon Marles-Wright Dr Olivier Delumeau Dr Susan Firbank Dr James Murray Dr Joseph Newman et al. | Molecular architecture of the "stressosome," a signal integration and transduction hub | 2008 |
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Dr Jon Marles-Wright Professor Rick Lewis
| The Bacillus subtilis stressosome: A signal integration and transduction hub | 2008 |
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Sukhvinder Gill Dr Rory O'Neill Professor Rick Lewis Professor Bernard Connolly
| Interaction of the family-B DNA polymerase from the archaeon Pyrococcus furiosus with deaminated bases | 2007 |
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Dr Jon Marles-Wright Professor Rick Lewis
| Stress responses of bacteria | 2007 |
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Steven Hardwick Dr Olivier Delumeau Dr Jon Marles-Wright Professor Rick Lewis
| Structural and Functional Characterization of Partner Switching Regulating the Environmental Stress Response in Bacillus subtilis | 2007 |
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Elizabeth Dridge Professor Rick Lewis Dr Clive Butler
| Developing structure-based models to predict substrate specificity of D-group (Type II) molybdenum enzymes: application to a molybdo-enzyme of unknown function from Archaeglobus fulgidus | 2006 |
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Dr Olivier Delumeau Dr James Murray Professor Rick Lewis
| High-molecular-weight complexes of RsbR and paralogues in the environmental signaling pathway of Bacillus subtilis | 2006 |
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He Fang Xie Dr James Flint Professor Jeremy Lakey Professor Rick Lewis Emeritus Professor Harry Gilbert et al. | Probing the Structural Basis for the Difference in Thermostability Displayed by Family 10 Xylanases | 2006 |
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Dr James Flint Professor Rick Lewis Emeritus Professor Harry Gilbert Dr James Murray
| A family 10 Thermoascus aurantiacus xylanase utilizes arabinose decorations of xylan as significant substrate specificity determinants | 2005 |
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Professor Rick Lewis
| Molecular insights into the initiation of sporulation in Gram-positive bacteria: new technologies for an old phenomenon | 2005 |
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Dr James Murray Dr Olivier Delumeau Professor Rick Lewis
| Structure of a nonheme globin in environmental stress signaling | 2005 |
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Professor Rick Lewis
| The RsbRST stress module in bacteria: a signalling system that may interact with different output modules | 2005 |
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Professor Rick Lewis
| Dimer-induced signal progation in Spo0A | 2004 |
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Professor Rick Lewis
| DNA-binding studies on the Bacillus subtilis transcriptional regulator and AbrB homologue, SpoVT | 2004 |
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Dr Olivier Delumeau Steven Hardwick Professor Rick Lewis
| Functional and Structural Characterization of RsbU, a Stress Signaling Phosphatase 2C | 2004 |
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Professor Rick Lewis Dr Olivier Delumeau
| A supramolecular complex in the environmental stress signaling pathway of Bacillus subtilis | 2003 |
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Professor Rick Lewis
| Crystallisation and preliminary crystallographic analysis of the kinase-recruitment domain of the PP2C-type phosphatase, RsbU | 2003 |
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Professor Rick Lewis
| Response regulator Spo0A from Bacillus subtilis is heterologously phosphorylated in Escherichia coli | 2003 |
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Professor Rick Lewis Dr David Scott
| Dimer formation and transcription activation in the sporulation response regulator Spo0A | 2002 |
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Dr David Scott Professor Rick Lewis
| Oligomerization of the Bacillus subtilis division protein DivIVA | 2002 |
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Dr Olivier Delumeau Professor Rick Lewis
| Protein-protein interactions that regulate the energy stress activation of σB in Bacillus subtilis. | 2002 |
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Professor Rick Lewis
| Crystal structure of GerE, the ultimate transcriptional regulator of spore formation in Bacillus subtilis | 2001 |
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Professor Rick Lewis
| Crystallisation and preliminary X-ray analysis of the sporulation factor SpoIIAA in both its native and phosphorylated forms | 2001 |
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Professor Rick Lewis
| Lessons and questions from the structure of the Spo0A activation domain: Response | 2001 |
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Professor Rick Lewis
| Structure of the Bacillus cell fate determinant SpoIIAA in phosphorylated and unphosphorylated forms. | 2001 |
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Professor Rick Lewis
| The structural basis for control by phosphorylation | 2001 |
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