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Browsing publications by Dr Simon Cockell.

Newcastle AuthorsTitleYearFull text
Chile Siachisumo
Dr Sara Luzzi
Saad Aldalaqan
Dr Gerald Hysenaj
Caroline Dalgliesh
et al.
An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression2024
Professor Fiona Oakley
Dr Simon Cockell
Dr Olivier Govaere
Professor Ann Daly
Professor Arun Sanyal
et al.
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)2024
Dr Olivier Govaere
Dr Simon Cockell
Michalina Zatorska
Kristy Wonders
Professor Dina Tiniakos
et al.
Pharmacogene expression during progression of metabolic dysfunction-associated steatotic liver disease: Studies on mRNA and protein levels and their relevance to drug treatment2024
Neela Codadu
Dr Simon Cockell
Professor Andrew Trevelyan
Dr Ryley Parrish
RNA Sequencing Demonstrates Ex Vivo Neocortical Transcriptomic Changes Induced by Epileptiform Activity in Male and Female Mice2024
Dr Olivier Govaere
Dr Megan Hasoon
Dr Simon Cockell
Dr Dina Tiniakos
Professor Ann Daly
et al.
A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures2023
Lefteris Zormpas
Dr Rachel Queen
Dr Simon Cockell
Mapping the transcriptome: Realizing the full potential of spatial data analysis2023
Dr Rachel Queen
Moira Crosier
Dr Lorraine Eley
Dr Janet Kerwin
Jasmin Turner
et al.
Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves2023
Hannah Smith
Francesco Kumara Mastrorosa
Dr Giles Holt
Dr Brendan Houston
Dr Bilal Alobaidi
et al.
A de novo paradigm for male infertility2022
Dr Paul Donaghy
Dr Simon Cockell
Dr Carmen Martin-Ruiz
Dr Jonathan Coxhead
Dr Joseph Kane
et al.
Blood mRNA expression in Alzheimer’s disease and dementia with Lewy bodies2022
Andrea Masi
Professor Chris Lamb
Dr Simon Cockell
Dr Jonathan Coxhead
Professor Nicholas Embleton
et al.
Distinct gene expression profiles between human preterm- and adult-derived intestinal organoids exposed to Enterococcus faecalis: A pilot study2022
Dr Katherine James
Professor Anil Wipat
Dr Simon Cockell
Expanding Interactome Analyses beyond Model Eukaryotes2022
Dr Katherine Johnson
Dr Peter Leary
Dr Olivier Govaere
Dr Matthew Barter
Sarah Charlton
et al.
Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance2022
Dr Katherine James
Aoesha Alsobhe
Dr Simon Cockell
Professor Anil Wipat
Dr Matthew Pocock
et al.
Integration of probabilistic functional networks without an external Gold Standard2022
Dr Harish Datta
Dr Stephen Tuck
Dr Simon Cockell
Michael Prediger
Dr Mark Birch
et al.
Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis2022
Dr Aidan Hanrath
Catherine Hatton
Dr Florian Gothe
Connie Browne
Dr Simon Cockell
et al.
Type I Interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia2022
Dr Olivier Govaere
Dr Dina Tiniakos
Professor Pierre Bedossa
Dr Simon Cockell
Dr Massimo Younes
et al.
NASH limits anti-tumor surveillance in immunotherapy-treated HCC2021
Rachel Roberts
Dr Sophie Weatherhead
Dika Pawitri
Dr Graham Smith
Dr Ashley Rider
et al.
Therapeutic wavelengths of ultraviolet B radiation activate apoptotic, circadian rhythm, redox signalling and key canonical pathways in psoriatic epidermis2021
Dr Olivier Govaere
Dr Simon Cockell
Professor Ann Daly
Professor Quentin Anstee
Transcriptomics Identify Thrombospondin-2 as a Biomarker for Nonalcoholic Steatohepatitis and Advanced Liver Fibrosis2021
Professor Quentin Anstee
Dr Rebecca Darlay
Dr Simon Cockell
Dr Olivier Govaere
Dr Dina Tiniakos
et al.
Genome-Wide Association Study of Non-Alcoholic Fatty Liver and Steatohepatitis in a Histologically-Characterised Cohort2020
Stephen Ball
Dr Simon Cockell
Emerita Professor Janet Wilson
Professor Derek Mann
Professor Andrew Fisher
et al.
Microarray analysis of primary epithelial and fibroblast cells in chronic rhinosinusitis without nasal polyps2020
Dr Olivier Govaere
Dr Simon Cockell
Dr Dina Tiniakos
Dr Rachel Queen
Dr Massimo Younes
et al.
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis2020
Dr Rachel Queen
Dr Simon Cockell
Professor Majlinda Lako
Understanding the complexity of retinal and pluripotent stem cell derived retinal organoids with single cell RNA sequencing: current progress, remaining challenges and future prospectives2020
Dr Helen Phillips
Catherine Stothard
Dr Wasay Shaikh Qureshi
Dr Alberto Briones Leon
Ramada Khasawneh
et al.
Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis2019
Dr Ingrid Ehrmann
Dr Katherine James
Yilei Liu
Dr Sushma Grellscheid
Dr Jannetta Steyn
et al.
An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning2019
Dr Jennifer Munkley
SR Gokul Krishnan
Gerald Hysenaj
Dr Emma Scott
Caroline Dalgliesh
et al.
Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer2019
Kat Cheung
Marjolein Burgers
Professor David Young
Dr Simon Cockell
Dr Louise Reynard
et al.
Correlation of Infinium HumanMethylation450K and MethylationEPIC BeadChip arrays in cartilage2019
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Raf Hussain
et al.
Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina2019
Dr Kirsty Hodgson
Dr Ed Schwalbe
Dr Jonathan Coxhead
Naomi Sinclair
Dr Simon Cockell
et al.
Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome2019
Dr Olivier Govaere
Dr Simon Cockell
Dr Arianna Bianchi
High-throughput sequencing identifies aetiology-dependent differences in ductular reaction in human chronic liver disease2019
Dr Katarzyna Szoltysek
Dr Simon Cockell
Professor Neil Perkins
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation2018
Dr Katherine James
Dr Simon Cockell
Dr Colin Gillespie
Dr Jennifer Hallinan
Dr Francesca Barone
et al.
B-cell activity markers are associated with different disease activity domains in primary Sjögren's syndrome2018
Dr Katarzyna Szoltysek
Dr Anna Walaszczyk
Dr Simon Cockell
Pro-inflammatory cytokine and high doses of ionizing radiation have similar effects on the expression of NF-kappaB-dependent genes2018
Dr Alex Elder
Dr Simon Bomken
Dr Ian Wilson
Dr Helen Blair
Dr Simon Cockell
et al.
Abundant and equipotent founder cells establish and maintain acute lymphoblastic leukaemia2017
Dr Louise Pease
Dr Carole Proctor
Dr Daryl Shanley
Dr Simon Cockell
Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females2017
Dr Katherine James
Dr Simon Cockell
Professor Nikolay Zenkin
Deep sequencing approaches for the analysis of prokaryotic transcriptional boundaries and dynamics2017
Dr Katherine James
Dr Pamela Gamba
Dr Simon Cockell
Professor Nikolay Zenkin
Misincorporation by RNA polymerase is a major source of transcription pausing in vivo2017
Dr Anna Moles Fernandez
Dr Jacqueline Butterworth
Dr Jill Hunter
Dr Jack Leslie
Helene Sellier
et al.
A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-kB dependent liver regeneration and cancer2016
Joseph Mullen
Dr Simon Cockell
Professor Anil Wipat
An Integrated Data Driven Approach to Drug Repositioning Using Gene-Disease Associations2016
Dr Ahmad Khundakar
Dr Peter Hanson
Dr Daniel Erskine
Dr Nichola Lax
Evangelia Karyka
et al.
Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations2016
Joseph Mullen
Dr Simon Cockell
Professor Anil Wipat
Mining integrated semantic networks for drug repositioning opportunities2016
Dr Jill Hunter
Dr Jacqueline Butterworth
Helene Sellier
Huw Thomas
Dr Christopher Bacon
et al.
The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma2016
Dr Catherine Meplan
Dr Simon Cockell
David Bradburn
Dr Daniel Commane
Dr Ramesh Arasaradnam
et al.
Transcriptomics and proteomics show that selenium affects inflammation, cytoskeleton, and cancer pathways in human rectal biopsies2016
Dr Joy Hardyman-Carlile
Dr John Tyson
Dr Kelly Jackson
Christine Aldridge
Dr Simon Cockell
et al.
Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc2016
Dr Katherine James
Shereen Al-Ali
Dr Jessica Tarn
Dr Simon Cockell
Dr Colin Gillespie
et al.
A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren’s Syndrome2015
Jessica Tarn
Dr Simon Cockell
Dr Colin Gillespie
Emerita Professor Julia Newton
Professor Anil Wipat
et al.
A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome2015
Dr Al Gabriel
Fadhel Alsaid Naji
Dr Ed Schwalbe
Dr Sirintra Nakjang
Dr Simon Cockell
et al.
Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia2015
Shereen Al-Ali
Dr Jessica Tarn
Dr Simon Cockell
Dr Colin Gillespie
Professor John Isaacs
et al.
Gene Set Enrichment Analysis Across Multiple Expression Studies Reveals a Core Subset of Primary Sjögren's Syndrome-Related Genes2015
Dr Marion Dubarry
Dr Conor Lawless
Dr Andrew Banks
Dr Simon Cockell
Professor David Lydall
et al.
Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae2015
Dr Alex Elder
Dr Helen Blair
Katie Dormon
Dr Simon Bomken
Dr Simon Cockell
et al.
High Abundance of Acute Lymphoblastic Leukaemia Founder Clones Does Not Translate to Functional Heterogeneity2015
Shereen Al-Ali
Dr Simon Cockell
Dr Jessica Tarn
Dr Katherine James
Sarah Bowman
et al.
Identification of Whole Blood Gene Expression Signature in Primary Sjogren's Syndrome Associated Lymphoma2015
Dr Simon Cockell
Dr Colin Gillespie
Professor Fai Ng
Serum Free Light Chains are Associated with Clinical Disease Activity of Primary Sjögren's Syndrome in the Cutaneous, Biological and Renal Domains2015
Dr Luisa Wakeling
Laura Ions
Suzie Escolme
Dr Simon Cockell
Tianhong Su
et al.
SIRI1 effects DNA methylation of polycomb protein target genes, a hotspot of the epigenetic shift observed in ageing2015
Ogo Ogo
Dr John Tyson
Dr Simon Cockell
Dr Alison Howard
Professor Ruth Valentine
et al.
The zinc finger protein ZNF658 regulates the transcription of genes involved in zinc homeostasis and affects ribosome biogenesis through the zinc transcriptional regulatory element (ZTRE)2015
Dr Keith Flanagan
Dr Simon Cockell
Professor Colin Harwood
Dr Jennifer Hallinan
Dr Sirintra Nakjang
et al.
A distributed computational search strategy for the identification of diagnostics targets: Application to finding aptamer targets for methicillin-resistant staphylococci2014
Dr Simon Cockell
Dr Colin Gillespie
Professor Fai Ng
Baff and B2m, but not Free Light Chains, Correlate with Disease Activity in Primary Sjögren's Syndrome (PSS)2014
Dr Simon Cockell
Dr Matthew Bashton
Dr Colin Gillespie
Bioconductor tools for microarray data analysis2014
Dr Andreas Werner
Dr Simon Cockell
Dr Jane Falconer
Mark Carlile
Dr Sammer Alnumeir
et al.
Contribution of natural antisense transcription to an endogenous siRNA signature in human cells2014
Shereen Al-Ali
Dr Simon Cockell
Andrew Skelton
Dr Katherine James
Dr Jessica Tarn
et al.
Identification of Whole Blood Gene Expression Signature in Primary Sjogren's Syndrome Associated Lymphoma2014
Dr Alessio Iannetti
Dr Adeline Ledoux
Dr Susan Tudhope
Helene Sellier
Adam Moore
et al.
Regulation of p53 and Rb Links the Alternative NF-kappaB Pathway to EZH2 Expression and Cell Senescence2014
Dr Phillip Probert
Git Chung
Dr Simon Cockell
Professor Loranne Agius
Steven White
et al.
Utility of B-13 Progenitor-Derived Hepatocytes in Hepatotoxicity and Genotoxicity Studies2014
Dr Jessica Tarn
Dr Simon Cockell
Dr Colin Gillespie
Shereen Al-Ali
Dr Katherine James
et al.
Whole Blood microRNA Signature for Primary Sjogren's Syndrome-Related Lymphoma2014
Dr Arthur Pratt
Dr Philip Brown
Dr Simon Cockell
Gillian Wilson
Professor John Isaacs
et al.
A CD4+T-Cell Gene Expression Signature Predicts Drug Survival on Methotrexate Monotherapy in Early Rheumatoid Arthritis2013
Dr Victoria Nesbitt
Dr Robert Pitceathly
Dr Simon Cockell
Professor Michael Hanna
Professor Patrick Chinnery
et al.
The Medical Research Council Neuromuscular Centre for Translational Research Mitochondrial Disease Patient Cohort Study UK: From Conceptualisation to Utilisation2013
Dr Simon Cockell
Dr Harish Datta
Transcriptome Profiling Reveals that Postmenopausal Osteoporosis and Bone Density Correlate with Fat Metabolism but not Adiposity2013
Dr Arthur Pratt
Dr Philip Brown
Dr Simon Cockell
Gillian Wilson
Professor John Isaacs
et al.
A CD4+T-Cell Gene Expression Signature Predicts Drug Survival On Methotrexate Monotherapy in Early Rheumatoid Arthritis.2012
Jochen Weile
Dr Katherine James
Dr Jennifer Hallinan
Dr Simon Cockell
Dr Phillip Lord
et al.
Bayesian integration of networks without gold standards2012
Dr Kay Padget
Hannah Curtis
Dr Ian Cowell
Dr Zbyslaw Sondka
Dr Nick Morris
et al.
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA2012
Dr Victoria Nesbitt
Dr Robert Pitceathly
Dr Simon Cockell
Professor Michael Hanna
Emeritus Professor Doug Turnbull
et al.
The medical research council neuromuscular centre for translational research mitochondrial disease patient cohort study UK: from conceptualisation to utilisation2012
Dr Phillip Lord
Dr Simon Cockell
Three Steps to Heaven: Semantic Publishing in a Real World Workflow2012
Dr Goksel Misirli
Dr Jennifer Hallinan
Dr Matthew Pocock
Dr Simon Cockell
Jochen Weile
et al.
BacillOndex: An Integrated Data Resource for Systems and Synthetic Biology2011
Dr Daniel Swan
Dr Simon Cockell
BioStar: An Online Question & Answer Resource for the Bioinformatics Community2011
Jochen Weile
Dr Matthew Pocock
Dr Simon Cockell
Dr Phillip Lord
James Dewar
et al.
Customizable views on semantically integrated networks for systems biology2011
Dr Simon Cockell
Dr Phillip Lord
Kcite - A tool for producing citations and bibliographies in WordPress posts2011
Dr Simon Cockell
Dr Phillip Lord
Mathjax-Latex Wordpress Plugin2011
Dr Simon Cockell
Professor Anil Wipat
Professor Colin Harwood
Dr Neil Keegan
Structure-function studies of an engineered scaffold protein derived from Stefin A. II: Development and applications of the SQT variant.2011
Dr Simon Cockell
Jochen Weile
Dr Phillip Lord
Dmytro Andriychenko
Dr Matthew Pocock
et al.
An integrated dataset for in silico drug discovery2010
Dr Kaveh Emami
Dr Nick Morris
Dr Simon Cockell
Professor Angharad MR Gatehouse
Changes in Protein Expression Profiles between a Low Phytic Acid Rice (Oryza sativa L. Ssp japonica) Line and Its Parental Line: A Proteomic and Bioinformatic Approach2010
Dr Frank Gibson
Dr Simon Cockell
Guidelines for reporting the use of gel image informatics in proteomics2010
Dr Simon Cockell
Structure-based evaluation of in silico predictions of protein-protein interactions using Comparative Docking2007