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Browsing publications by
Dr Kay Padget.
Newcastle Authors
Title
Year
Full text
Catriona Manville
Kayleigh Smith
Dr Zbyslaw Sondka
Holly Rance
Dr Ian Cowell
et al.
Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells
2015
Dr Katrin Jaedicke
Dr Kay Padget
Dr Stephen Todryk
Professor Philip Preshaw
Dr John Taylor
et al.
Leptin up-regulates TLR2 in human monocytes
2013
Dr Ian Cowell
Dr Zbyslaw Sondka
Kayleigh Smith
Ka Lee
Catriona Manville
et al.
Model for
MLL
translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity
2012
Dr Kay Padget
Hannah Curtis
Dr Ian Cowell
Dr Zbyslaw Sondka
Dr Nick Morris
et al.
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA
2012
Dr Ian Cowell
Dr Nikolaos Papageorgiou
Dr Kay Padget
Professor Caroline Austin
Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin
2011
Catriona Manville
Dr Emma Clark
Dr Kay Padget
james Harvey
Dr Nick Morris
et al.
Bioinformatic analysis of topoisomerase II binding sites
2007
Dr Miguel Lopez-Lazaro
Dr Elaine Willmore
Andrew Jobson
Kathryn Gilroy
Hannah Curtis
et al.
Curcumin induces high levels of topoisomerase I- and II-DNA complexes in K562 leukemia cells
2007
Kathryn Gilroy
Chrysoula Leontiou
Dr Kay Padget
Professor Jeremy Lakey
Professor Caroline Austin
et al.
mAMSA resistant human topoisomerase IIβ mutation G465D has reduced ATP hydrolysis activity
2006
Dr Kay Padget
Professor Caroline Austin
Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis
2001
Dr Kay Padget
Dr Michael Tilby
Professor Caroline Austin
An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2,1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells
2000
Dr Kay Padget
Professor Andrew Pearson
Dr Michael Tilby
Professor Caroline Austin
Camptothecin-stabilised topoisomerase I-DNA complexes in leukaemia cells visualised and quantified in situ by the TARDIS assay (trapped in agarose DNA immunostaining)
2000
Dr Kay Padget
Professor Andrew Pearson
Professor Caroline Austin
Quantitation of DNA topoisomerase II alpha and beta in human leukaemia cells by immunoblotting
2000
Dr Kay Padget
Professor Andrew Pearson
Professor Caroline Austin
Quantitation of DNA topoisomerase IIalpha and beta in human leukaemia cells by immunoblotting
2000
Dr Elaine Willmore
Dr Adrian Frank
Dr Kay Padget
Dr Michael Tilby
Professor Caroline Austin
et al.
Etoposide targets topoisomerase IIα and IIβ in leukemic cells: Isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique
1998