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Browsing publications by
Dr Jonathan Coxhead.
Newcastle Authors
Title
Year
Full text
Dr Jamie Soul
Yao Hao
Hua Lin
Dr Katarzyna Pirog
Dr Jonathan Coxhead
et al.
Comparative transcriptomic analysis of articular cartilage of post-traumatic osteoarthritis mouse models.
2024
Marina Moya-Molina
Emily Flood
Dr Jonathan Coxhead
Dr Graham Smith
Professor Lyle Armstrong
et al.
Deciphering the impact of
PROM1
alternative splicing on human photoreceptor development and maturation
2024
Dr Joseph Collin
Dr Agata Rozanska
Dr Veronika Boczonadi
Marina Moya Molina
Adrienne Unsworth
et al.
Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level
2024
Ben Whittle
Dr Hannah Lowes
Dr Dasha Deen
Dr Angela Pyle
Dr Jonathan Coxhead
et al.
Early-stage idiopathic Parkinson's disease is associated with reduced circular RNA expression
2024
Dr Joseph Collin
Dr Agata Rozanska
Zerti Zerti
Adrienne Unsworth
Moira Crosier
et al.
Single-cell analyses reveal transient retinal progenitor cells in the ciliary margin of developing human retina
2024
Dr Ken Baker
Dr David McDonald
Dr Gill Hulme
Raf Hussain
Dr Jonathan Coxhead
et al.
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission
2024
Dr Angela Pyle
Dr Brendan Payne
Dr Jonathan Coxhead
Professor Gavin Hudson
Moira Crosier
et al.
Author Correction: Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos (Nature Cell Biology, (2018), 20, 2, (144-151), 10.1038/s41556-017-0017-8)
2023
Jing Lim
Grace Mallett
Dr David McDonald
Dr Gill Hulme
Dr Stephanie Laba
et al.
Programmed cell death-1 receptor-mediated regulation of Tbet
+
NK1.1
-
innate lymphoid cells within the tumor microenvironment
2023
Rebecca Harris
Dr Maninder Heer
Dr Mark Levasseur
Dr Tyrell Cartwright
Beth Weston
et al.
Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
2023
Dr Joseph Collin
Dr Megan Hasoon
Zerti Zerti
Sarah Hammadi
Professor David Steel
et al.
Single-cell RNA sequencing reveals transcriptional changes of human choroidal and retinal pigment epithelium cells during fetal development, in healthy adult and intermediate age-related macular degeneration
2023
Dr Rachel Queen
Moira Crosier
Dr Lorraine Eley
Dr Janet Kerwin
Jasmin Turner
et al.
Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves
2023
Jason Powell
Steven Powell
Michael Mather
Lauren Beck
Dr Pawel Palmowski
et al.
Tracheostomy in children is associated with neutrophilic airway inflammation
2023
Hannah Smith
Francesco Kumara Mastrorosa
Dr Giles Holt
Dr Brendan Houston
Dr Bilal Alobaidi
et al.
A
de novo
paradigm for male infertility
2022
Dr Paul Donaghy
Dr Simon Cockell
Dr Carmen Martin-Ruiz
Dr Jonathan Coxhead
Dr Joseph Kane
et al.
Blood mRNA expression in Alzheimer’s disease and dementia with Lewy bodies
2022
Robert Jackson
Catherine Hatton
Dr Jarmila Spegarova
Dr Maria Georgiou
Dr Joseph Collin
et al.
Conjunctival epithelial cells resist productive SARS-CoV-2 infection
2022
Andrea Masi
Professor Chris Lamb
Dr Simon Cockell
Dr Jonathan Coxhead
Professor Nicholas Embleton
et al.
Distinct gene expression profiles between human preterm- and adult-derived intestinal organoids exposed to
Enterococcus faecalis
: A pilot study
2022
Dr Angela Pyle
Dr Helen Griffin
Dr Jonathan Coxhead
Raf Hussain
Professor Gavin Hudson
et al.
Heteroplasmic mitochondrial DNA variants in cardiovascular diseases
2022
Dr Deepali Pal
Dr Helen Blair
Sean Hockney
Dr Melanie Beckett
Mankaran Singh
et al.
hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia
2022
Dr Jill Hunter
Dr Jacqueline Butterworth
Helene Sellier
Dr Nicola Hannaway
Dr Saimir Luli
et al.
Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance
2022
Dr Agata Rozanska
Rodrigo Cerna Chavez
Dr Rachel Queen
Dr Joseph Collin
Dr Darin Zerti
et al.
pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell differentiation
2022
Dr Jill Hunter
Dr Nicola Hannaway
Scott Kerridge
Dr Saimir Luli
Dr Jacqueline Butterworth
et al.
Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway
2022
Dr Marzena Kurzawa-Akanbi
Dr Florence Burte
Dr Birthe Hilgen
Dr Rachel Queen
Dr Jonathan Coxhead
et al.
Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina
2022
Dr Marina Danilenko
Dr Claire Keeling
Dr Stephen Crosier
Dr Martina Finetti
Dr Daniel Williamson
et al.
Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development
2022
Lauren Beck
Andrea Masi
Professor Chris Lamb
Rachel Smith
Dr Jonathan Coxhead
et al.
Strain-specific impacts of probiotics are a significant driver of gut microbiome development in very preterm infants
2022
Dr Jill Hunter
Scott Kerridge
Dr Nicola Hannaway
Dr Saimir Luli
Dr Iglika Ivanova
et al.
Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells
2022
Ramada Khasawneh
Dr Ralf Kist
Dr Rachel Queen
Raf Hussain
Dr Jonathan Coxhead
et al.
Msx1
haploinsufficiency modifies the
Pax9
-deficient cardiovascular phenotype
2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Sanja Bojic
Nicky Moyse
et al.
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells
2021
Dr Laura Jardine
Dr Simone Webb
Issac Goh
Dr Gary Reynolds
Dr Michael Mather
et al.
Blood and immune development in human fetal bone marrow and Down syndrome
2021
Catherine Hatton
Dr Rachel Botting
Dr Maria Duenas Fadic
Dr Iram Haq
Dr Bernard Verdon
et al.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2
2021
Dr Gary Reynolds
Dr Peter Vegh
Dr James Fletcher
Dr Beth Poyner
Dr Emily Stephenson
et al.
Developmental cell programs are co-opted in inflammatory skin disease
2021
Emily Stephenson
Dr Gary Reynolds
Dr Rachel Botting
Justin Engelbert
Dr Bayanne Olabi
et al.
Single-cell multi-omics analysis of the immune response in COVID-19
2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Maria Georgiou
et al.
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface
2020
Dr Hannah Lowes
Dr Fiona Robertson
Dr Angela Pyle
Raf Hussain
Dr Jonathan Coxhead
et al.
The Human Coronavirus Receptor ANPEP (CD13) Is Overexpressed in Parkinson's Disease
2020
Dr Joseph Collin
Dr Darin Zerti
Dr Rachel Queen
Dr Roman Bauer
Dr Jonathan Coxhead
et al.
CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones
2019
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Raf Hussain
et al.
Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina
2019
Dr Kirsty Hodgson
Dr Ed Schwalbe
Dr Jonathan Coxhead
Naomi Sinclair
Dr Simon Cockell
et al.
Epigenetic modifiers
DNMT3A
and
BCOR
are recurrently mutated in
CYLD
cutaneous syndrome
2019
Dr Christopher Duncan
Angela Grainger
Andrew Skelton
Raf Hussain
Dr Joe Willet
et al.
Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in
TNFAIP3
(A20)
2018
Dr Lauren Walker
Dr Jonathan Coxhead
Dr Ian Wilson
Dr Matthew Bashton
Dr Christopher Morris
et al.
High prevalence of focal and multi-focal somatic genetic variants in the human brain
2018
Dr Vasileios Floros
Dr Angela Pyle
Dr Wei Wei
Dr Brendan Payne
Dr Jonathan Coxhead
et al.
Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos
2018
Dr Michael Keogh
Dr Wei Wei
Dr Ian Wilson
Dr Jonathan Coxhead
Dr Helen Griffin
et al.
Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource
2017
Dr Michael Keogh
Dr Ian Wilson
Dr Jonathan Coxhead
Dr Helen Griffin
Dr Marzena Kurzawa-Akanbi
et al.
Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains
2017
Emerita Professor Susan Lindsay
Dr Yaobo Xu
Dr Steven Lisgo
Lauren Harkin
Dr Gavin Clowry
et al.
HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development
2016
Dr Jonathan Coxhead
Dr Marzena Kurzawa-Akanbi
Raf Hussain
Dr Angela Pyle
Professor Patrick Chinnery
et al.
Somatic mtDNA variation is an important component of Parkinson's disease
2016
Dr Brendan Payne
Kris Gardner
Dr Jonathan Coxhead
Professor Patrick Chinnery
Deep Resequencing of Mitochondrial DNA
2015
Dr Angela Pyle
Professor Gavin Hudson
Dr Ian Wilson
Dr Jonathan Coxhead
Tania Smertenko
et al.
Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans
2015
Dr Charalampos Tzoulis
Dr Jonathan Coxhead
Dr Brendan Payne
Professor Patrick Chinnery
Professor Laurence Bindoff
et al.
Molecular Pathogenesis of Polymerase Gamma-Related Neurodegeneration
2014
Dr Gerald Pfeffer
Professor Grainne Gorman
Dr Helen Griffin
Dr Marzena Kurzawa-Akanbi
Dr Ian Wilson
et al.
Mutations in the
SPG7
gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance
2014
Dr Maria Lastowska
Hani Al-Afghani
Haya AL-Balool
Harsh SHETH
Dr Jonathan Coxhead
et al.
Identification of a neuronal transcription factor network involved in medulloblastoma development
2013
Smatanova Borras
Dayne Bromley
Philip Scully
Dr Jonathan Coxhead
Dr Ann Curtis
et al.
'Noonan Spectrum Test' - comprehensive screening for RASopathies
2012
Dr Brendan Payne
Dr Ian Wilson
Dr Patrick Yu Wai Man
Dr Jonathan Coxhead
Professor David Deehan
et al.
Universal heteroplasmy of human mitochondrial DNA
2012
Haya AL-Balool
Dr Mark Wade
Dr Jonathan Coxhead
Professor Julie Irving
Professor David Elliott
et al.
Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant
2011
Dr Jonathan Coxhead
Seamus Kelly
Professor John Mathers
Differential antineoplastic effects of butyrate in cells with and without a functioning DNA mismatch repair
2010
Dr Jonathan Coxhead
Seamus Kelly
Professor Sir John Burn
Professor John Mathers
Cell kinetics and gene expression changes in colorectal cancer patients given resistant starch: a randomised controlled trial
2009
Dr Mark Leaver
Dr Patricia Dominguez Cuevas
Dr Jonathan Coxhead
Dr Richard Daniel
Professor Jeff Errington
et al.
Life without a wall or division machine in
Bacillus subtilis
2009
Dr Jonathan Coxhead
Professor Sir John Burn
Dr Ann Curtis
Early experiences in amplicon sequencing using the Roche GS-FLX massively parallel DNA sequencer and its application within a diagnostic laboratory
2008
Dr Jonathan Coxhead
Seamus Kelly
Professor John Mathers
Role of DNA-mismatch repair in anti-neoplastic effects of butyrate
2008
Professor John Mathers
Dr Jonathan Coxhead
Dr John Tyson
Nutrition and DNA repair - Potential molecular mechanisms of action
2007
Dr Jonathan Coxhead
Seamus Kelly
Professor John Mathers
Role of resistant starch in colorectal cancer prevention: A prospective randomised controlled trial
2007
Dr Jonathan Coxhead
Wendy Bal
Dr Liz Williams
Professor John Mathers
Reactive oxygen species generation in mismatch repair-proficient and -deficient colorectal cancer cell lines exposed to butyrate
2006
Dr Jonathan Coxhead
Dr Liz Williams
Professor John Mathers
DNA mismatch repair status may influence anti-neoplastic effects of butyrate
2005
Dr Jonathan Coxhead
Wendy Bal
Dr Brian Shenton
Dr Liz Williams
Professor John Mathers
et al.
Effect of butyrate on induction of aneuploidy in colorectal carcinoma cell lines
2005
Dr Liz Williams
Dr Jonathan Coxhead
Professor John Mathers
Anti-cancer effects of butyrate: Use of micro-array technology to investigate mechanisms
2003