Browse by author
Lookup NU author(s): Dr Celine CanoORCiD, Emeritus Professor Bernard Golding, Dr Ian HardcastleORCiD, Professor Nicola CurtinORCiD, Professor Roger Griffin
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
The synthesis and biological evaluation of libraries of 8-biarylchromen-4-ones enabled the elucidation of structure-activity relationships for inhibition of the DNA-dependent protein kinase (DNA-PK), with 8-(3-(thiophen-2-yl)phenyl)chromen-4-one and 8-(3-(thiophen-3-yl)phenyl)chromen-4-one being especially potent inhibitors. © 2008 Elsevier Ltd. All rights reserved.
Author(s): Murr M, Cano C, Golding BT, Hardcastle IR, Hummersome M, Frigerio M, Curtin NJ, Menear K, Richardson C, Smith G, Griffin R
Publication type: Article
Publication status: Published
Journal: Bioorganic and Medicinal Chemistry Letters
Year: 2008
Volume: 18
Issue: 17
Pages: 4885-4890
Date deposited: 29/04/2010
ISSN (print): 0960-894X
ISSN (electronic): 1464-3405
Publisher: Pergamon
URL: http://dx.doi.org/10.1016/j.bmcl.2008.07.066
DOI: 10.1016/j.bmcl.2008.07.066
Altmetrics provided by Altmetric