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Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States

Lookup NU author(s): Professor Steven CliffordORCiD, Professor Deborah Tweddle, Dr Quentin Campbell Hewson

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).

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Author(s): George SL, Lynn C, Stankunaite R, Hughes D, Sauer CM, Chalker J, Waqar Ahmed S, Oostveen M, Proszek PZ, Yuan L, Shaikh R, Jamal S, Brew A, Tall J, Rogers T, Clifford SC, Vormoor J, Shipley JM, Tweddle DA, Jones C, Willis C, Burke GAA, Vedi A, Howell L, Johnston R, Rees H, Adams M, Jesudason A, Ronghe M, Elliott M, Ross E, Makin G, Campbell-Hewson Q, Grundy RG, Turnbull J, Wilson S, Lee V, Gray JC, Stoneham S, Gatz SA, Marshall LV, Angelini P, Anderson J, Cresswell GD, Graham TA, Al-Lazikani B, Cortes-Ciriano I, Kearns P, Hutchinson JC, Hargrave D, Jacques TS, Hubank M, Sottoriva A, Chesler L

Publication type: Article

Publication status: Published

Journal: Cancer Discovery

Year: 2025

Pages: epub ahead of print

Online publication date: 04/02/2025

Acceptance date: 17/12/2024

Date deposited: 04/03/2025

ISSN (print): 2159-8274

ISSN (electronic): 2159-8290

Publisher: American Association for Cancer Research

URL: https://doi.org/10.1158/2159-8290.CD-24-0916

DOI: 10.1158/2159-8290.CD-24-0916

Data Access Statement: All sequencing data used in this study have been made available on the European Genome-Phenome Archive under accession number: EGAS50000000549. Processed data have been made available on Mendeley (https://doi.org/10.17632/d2gynzkj42.1).

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