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Lookup NU author(s): Dr Ayat Bashir, John Hammond, Steven White, Professor James Shaw, Professor Sanjay PandanaboyanaORCiD
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© 2024 Lippincott Williams and Wilkins. All rights reserved. Objectives: This scoping review aims to provide evidence synthesis of continuous glucose monitoring (CGM) and insulin pump use after undergone total pancreatectomy (TP) with or without islet autotransplantation (TPIAT). Methods: The review was conducted adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) checklist. Results 15 studies including 147 patients (adult n=71/paediatric n=76) reported on CGM use post-TP (n=42) and TPIAT (n=105). 4 were randomized controlled trials and 10 observational studies. 6 studies evaluated CGM use in the peri-operative and 6 in the immediate post-operative period (n=8) with variable follow-up (14 hours -20 months). CGM was used as a stand-alone device (8 studies) which allowed assessment of dynamic islet function and detection of hypoglycemia (n=1) resulting in lower glucose levels (n=1). 6 studies evaluated insulin pump with CGM with reduction in post-operative mean glucose (n=4), and hypoglycaemic episodes (n=2). There were no patient reported outcome measures (PROMs) or quality of life (QoL) measures reported. Conclusions: CGM can be used following TP for glucose monitoring and/or linked with insulin pump device in the peri-operative period with improved glycaemic control. However, the data are limited by short follow-up and lack of PROMs and QoL measures.
Author(s): Bashir A, Joseph N, Hammond JS, White S, Abu-El-Haija M, Drewes AM, Shaw JAM, Pandanaboyana S
Publication type: Review
Publication status: Published
Journal: Pancreas
Year: 2024
Pages: Epub ahead of print
Online publication date: 29/11/2024
Acceptance date: 02/04/2018
ISSN (print): 0885-3177
ISSN (electronic): 1536-4828
Publisher: Lippincott Williams and Wilkins
URL: https://doi.org/10.1097/MPA.0000000000002424
DOI: 10.1097/MPA.0000000000002424
PubMed id: 39626176
