Toggle Main Menu Toggle Search

Open Access padlockePrints

Torching the Haystack: Modelling fast-fail strategies in drug development

Lookup NU author(s): Dr Dennis LendremORCiD, Dr Clare LendremORCiD

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Abstract

By quickly clearing the development pipeline of failing or marginal products, fast-fail strategies release resources to focus on more promising molecules. The Quick-Kill model of drug development demonstrates that fast-fail strategies will: (1) reduce the expected time to market; (2) reduce expected R&D costs; and (3) increase R&D productivity. This paper outlines the model and demonstrates the impact of fast-fail strategies. The model is illustrated with costs and risks data from pharmaceutical and biopharmaceutical companies.


Publication metadata

Author(s): Lendrem DW, Lendrem BC

Publication type: Article

Publication status: Published

Journal: Drug Discovery Today

Year: 2013

Volume: 18

Issue: 7-8

Pages: 331-336

Print publication date: 12/12/2012

ISSN (print): 1359-6446

ISSN (electronic): 1878-5832

Publisher: Elsevier

URL: http://dx.doi.org/10.1016/j.drudis.2012.11.011

DOI: 10.1016/j.drudis.2012.11.011


Altmetrics

Altmetrics provided by Altmetric


Share