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Lookup NU author(s): Emeritus Professor Tim Cawston
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Assay of collagenase activity involves the use of radiolabeled collagen. Stimulation of cartilage with proinflammatory cytokines results in the upregulation of collagenases and the subsequent release of degraded collagen fragments. These enzymes can be localized in both osteoarthritic and rheumatoid arthritis cartilage and synovial tissues.
Author(s): Cawston TE, Morgan TG
Editor(s): Cope, AP
Publication type: Book Chapter
Publication status: Published
Book Title: Arthritis Research
Year: 2007
Volume: 135
Pages: 211-226
Edition: 1st
Series Title: Methods in Molecular Medicine
Publisher: Humana Press, Inc.
Place Published: US
URL: http://dx.doi.org/10.1007/978-1-59745-401-8_13
DOI: 10.1007/978-1-59745-401-8_13
Notes: ISSN: 1543-1894 (Print) 1940-6037 (Online) Online ISBN: 9781597454018
Library holdings: Search Newcastle University Library for this item
ISBN: 9781588293442