Dr Sarah Fordham Dr Wei-Yu Lin Dr Helen Blair Dr Claire Elstob Dr Hayden Bell et al. | Biallelic TET2 mutations confer sensitivity to 5′-azacitidine in acute myeloid leukemia | 2023 |
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Professor James Allan
| Inherited cancer predisposing mutations in patients with therapy-related myeloid neoplasms | 2023 |
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Dr Jose Luis Marin-Rubio Dr Maria Duenas Fadic Dr Tiaan Heunis Dr Abeer Dannoura Dr Joe Inns et al. | A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia | 2022 |
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Dr Wei-yu Lin Dr Sarah Fordham Dr Nicola Sunter Dr Claire Elstob Dr Yaobo Xu et al. | Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (Nature Communications, (2021), 12, 1, (6233), 10.1038/s41467-021-26551-x) | 2022 |
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Dr Ricky Tirtakusuma Dr Katarzyna Szoltysek Professor Vasily Grinev Dr Sirintra Nakjang Dr Daniel Williamson et al. | Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia | 2022 |
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Dr Deepali Pal Dr Helen Blair Sean Hockney Dr Melanie Beckett Mankaran Singh et al. | hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia | 2022 |
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Professor James Allan
| Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility | 2021 |
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Dr Wei-Yu Lin Dr Sarah Fordham Dr Nicola Sunter Dr Claire Elstob Dr Thahira Rahman et al. | Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia | 2021 |
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Dr Wei-Yu Lin Dr Sarah Fordham Dr Nicola Sunter Dr Claire Elstob Dr Yaobo Xu et al. | Genome-wide association study identifies susceptibility loci for acute myeloid leukemia | 2021 |
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Professor James Allan Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman
| Author correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia | 2019 |
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Dr Nicola Sunter Professor Graham Jackson Professor James Allan
| Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology | 2019 |
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Professor James Allan
| Genetic susceptibility to breast cancer in lymphoma survivors | 2019 |
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Professor James Allan Professor Anthony Moorman
| Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk | 2019 |
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Professor James Allan
| Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics | 2019 |
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Professor James Allan
| Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 | 2019 |
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Professor James Allan Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman
| Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia | 2018 |
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Dr Sarah Fordham Dr Helen Blair Dr Claire Elstob Professor Ruth Plummer Dr Yvette Drew et al. | Inhibition of ATR acutely sensitises acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase | 2018 |
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Dr Lynsey McKenzie Hasan Issa Sandeep Potluri Dr Helen Blair Asmida Isa et al. | The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation | 2018 |
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Professor Anthony Moorman Professor Julie Irving Professor James Allan Professor Christine Harrison FRCPath FMedSci
| A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1 | 2017 |
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Dr Aiste McCormick Gavin Cuthbert Dr Rachel O'Donnell Dr Brian Wilson Huw Thomas et al. | Functional characterisation of a novel ovarian cancer cell line, NUOC-1 | 2017 |
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Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson Dr Helen Marr et al. | Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia | 2017 |
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Dr Nicola Sunter Professor Graham Jackson Dr Thahira Rahman Professor James Allan
| Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci | 2017 |
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Dr David Jamieson Dr Nicola Sunter Sara Muro Dr Nicola Cresti Julieann Sludden et al. | Pharmacogenetic association of MBL2 and CD95 polymorphisms with grade 3 infection following adjuvant therapy for breast cancer with doxorubicin and cyclophosphamide | 2017 |
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Professor Graham Jackson Professor James Allan
| Telomere length is a critical determinant for survival in multiple myeloma | 2017 |
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Professor James Allan
| Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism | 2016 |
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Dr Victoria Forster Mohammed Nahari Dr Natalia Martinez Soria Amy Bradburn Dr Sarah Fordham et al. | The leukemia-associated RUNX1/ETO oncoprotein confers a mutator phenotype | 2016 |
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Professor James Allan
| Whole-exome Sequence Analysis Implicates Rare Il17REL Variants in Familial and Sporadic Inflammatory Bowel Disease | 2016 |
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Dr Mark Wade Dr Nicola Sunter Dr Sarah Fordham Anna Long Dino Mašić et al. | c-MYC is a radiosensitive locus in human breast cells | 2015 |
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Professor James Allan
| Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis | 2015 |
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Fiona Middleton Dr Miranda Patterson Dr Claire Elstob Dr Sarah Fordham Dr Ashleigh Herriott et al. | Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition | 2015 |
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Dr Nicola Sunter Dr Helen Marr Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson et al. | Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk | 2015 |
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Dr Sarah Fordham Mike Cole Professor Julie Irving Professor James Allan
| Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia | 2015 |
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Professor Julie Irving Elizabeth Matheson Helen Blair Marian Case Isabella Swidenbank et al. | Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. Blood. 2014;124(23):3420-3430 | 2015 |
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Dr Helen Marr Dr Luke Gaughan Dr Susan Tudhope Professor James Allan
| Regulation of CD38 in IRF4 in Chronic Lymphocytic Leukaemia | 2015 |
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Professor James Allan
| Second cancers | 2015 |
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Professor Anthony Moorman Professor Julie Irving Professor James Allan Professor Christine Harrison FRCPath FMedSci
| The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A | 2015 |
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Dr Victoria Forster Mohammed Nahari Dr Natalia Martinez Soria Amy Bradburn Hesta McNeill et al. | The Leukemia-Associated RUNX1/ETO Oncoprotein Confers a Mutator Phenotype | 2015 |
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Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson Professor James Allan et al. | A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia | 2014 |
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Dr Sarah Fordham Mike Cole Professor Julie Irving Professor James Allan
| Cytarabine leaves a mutational fingerprint in relapsing leukemia | 2014 |
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Professor Julie Irving Elizabeth Matheson Dr Helen Blair Marian Case Isabella Swidenbank et al. | Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition | 2014 |
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Professor James Allan
| Second Malignant Neoplasms and Cardiovascular Disease Following Radiotherapy | 2014 |
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Professor James Allan
| Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease | 2014 |
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Professor James Allan
| Aetiology, genetics and prevention of secondary neoplasms in adult cancer survivors | 2013 |
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Professor Graham Jackson Professor Julie Irving Professor James Allan
| Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk | 2013 |
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Dr Sarah Fordham Dr Helen Marr Professor James Allan
| Searching for clarity in therapy-related myelodysplastic syndrome/acute myeloid leukemia prognostication | 2013 |
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Professor Julie Irving Professor James Allan
| Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype | 2013 |
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Dr Sarah Fordham Dr Victoria Forster Professor Graham Jackson Dr Simon Bomken Professor James Allan et al. | A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia | 2012 |
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Dr Andrea Beyerle Professor Olaf Heidenreich Professor James Allan
| AML1/ETO Confers a Mutator Phenotype in AML | 2012 |
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Professor Julie Irving Professor James Allan
| Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia | 2012 |
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Professor James Allan
| Second Malignant Neoplasms and Cardiovascular Disease Following Radiotherapy | 2012 |
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Dr Victoria Forster Dr Andrea Beyerle Professor Olaf Heidenreich Professor James Allan
| AML1/ETO Confers a Mutator Phenotype In Acute Myeloid Leukemia Associated with Downregulation of the Base-Excision-Repair Gene OGG1 | 2011 |
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Professor Julie Irving Professor James Allan
| DNA mismatch repair status affects cellular response to Ara-C and other anti-leukemic nucleoside analogs | 2011 |
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Dr Victoria Forster Amy Bradburn Professor James Allan Professor Olaf Heidenreich
| The Angiogenic Factor Angiopoietin-1 Is Regulated by the Acute Myeloid Leukemia Fusion Protein AML1/ETO | 2011 |
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Professor Graham Jackson Dr Simon Bomken Professor James Allan
| A Functional Polymorphism In the CD95 Cell Death Receptor Associated with Prognosis In Acute Promyelocytic Leukemia | 2010 |
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Dr Nicola Sunter Professor Graham Jackson Dr Simon Bomken Professor James Allan
| A Functional Polymorphism In the CD95 Cell Death Receptor Associated with Prognosis In Acute Promyelocytic Leukemia | 2010 |
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Professor Graham Jackson Dr Nicola Sunter Dr Andrew Hall Professor Julie Irving Professor James Allan et al. | A polymorphism in the 3' UTR of IRF4 linked to susceptibility and pathogenesis in chronic lymphocytic leukaemia and Hodgkin lymphoma has limited impact in multiple myeloma | 2010 |
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Professor Julie Irving Professor James Allan
| Cellular Response to Cytarabine Is Modulated by the DNA Mismatch Repair Pathway: Implications for Treatment of Acute Myeloid Leukemia | 2010 |
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Dr Sarah Fordham Emeritus Professor Keith Scott Professor Julie Irving Professor James Allan
| Cellular Response to Cytarabine is Modulated by the DNA Mismatch Repair Pathway: Implications for Treatment of Acute Myeloid Leukemia | 2010 |
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Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson Professor James Allan et al. | Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk | 2010 |
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Professor James Allan
| Genetic variation in the folate metabolic pathway and risk of childhood leukemia | 2010 |
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Professor Julie Irving Professor James Allan
| Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk | 2010 |
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Dr Rachel Crossland Professor Stephen Proctor Professor James Allan
| Mature MicroRNAs Mir 18, 19a, 19b, 17 5p and 92 of the Mir 17 92 Cluster Predict for Treatment Free Survival In Patients with Chronic Lymphocytic Leukaemia | 2010 |
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Dr Rachel Crossland Professor Stephen Proctor Professor James Allan Dr Tryfonia Mainou-Fowler
| Mature MicroRNAs Mir-18,-19a,-19b,-17-5p and-92 of the Mir-17-92 Cluster Predict for Treatment Free Survival In Patients with Chronic Lymphocytic Leukaemia | 2010 |
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Professor James Allan
| Melanocortin 1 receptor (MC1R), pigmentary characteristics and sun exposure: findings from a case-control study of diffuse large B-cell and follicular lymphoma | 2010 |
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Professor Julie Irving Professor James Allan
| MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukaemia | 2010 |
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Professor James Allan
| Non-Homologous End-Joining Gene Profiling Reveals Distinct Expression Patterns Associated with Lymphoma and Multiple Myeloma | 2010 |
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Professor James Allan
| Testicular Cancer Survivorship: Research Strategies and Recommendations | 2010 |
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Dr Victoria Forster Professor James Allan Professor Olaf Heidenreich
| The t(8,21) Fusion Protein AML1/ETO Promotes Susceptibility to Mutation In Acute Myeloid Leukemia | 2010 |
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Dr Victoria Forster Professor James Allan Professor Olaf Heidenreich
| The t(8;21) Fusion Protein AML1/ETO Promotes Susceptibility to Mutation In Acute Myeloid Leukemia | 2010 |
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Professor James Allan Dr Nicola Sunter Dr Andrew Hall Dr Christopher Bacon Jonathan Pointon et al. | Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia | 2010 |
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Professor Julie Irving Professor James Allan Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci
| Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk | 2010 |
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Professor James Allan
| [Meeting Abstract] DNA repair dysfunction and genomic instability in therapy-related malignancy | 2009 |
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Professor James Allan
| Association of Molecular Markers With Toxicity Outcomes in a Randomized Trial of Chemotherapy for Advanced Colorectal Cancer: The FOCUS Trial | 2009 |
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Professor James Allan
| Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility | 2009 |
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Professor Julie Irving Professor James Allan
| Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia | 2009 |
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Professor James Allan
| Polymorphisms in the nucleotide excision repair gene ERCC2/XPD and risk of non-Hodgkin lymphoma | 2009 |
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Professor James Allan
| MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility | 2008 |
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Professor James Allan Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson et al. | A Common Genetic Variant in the 3'UTR of IRF4/MUM1 Associates with Risk of Disease and Poor Prognosis in Chronic Lymphocytic Leukaemia | 2008 |
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Professor James Allan
| A Genome-Wide Analysis to Identify Novel Susceptibility Loci for Therapy-Related Acute Myeloid Leukemia | 2008 |
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Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson Professor James Allan et al. | A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia | 2008 |
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Professor James Allan
| Genetic susceptibility to radiogenic cancer in humans | 2008 |
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Professor James Allan
| Genetic variation in genes expressed in the germinal center and risk of B cell lymphoma among Caucasians | 2008 |
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Professor James Allan
| Influence of DNA repair gene polymorphisms on the initial repair of MMS-induced DNA damage in human lymphocytes as measured by the alkaline comet assay | 2008 |
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Professor James Allan
| MLH1 -93G>A promoter polymorphism and risk of mismatch repair deficient colorectal cancer | 2008 |
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Professor Graham Jackson Professor James Allan
| Polymorphic MLH1 and risk of cancer after methylating chemotherapy for Hodgkin lymphoma | 2008 |
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Professor James Allan
| Risk of Leukemia Among Survivors of Testicular Cancer: A Population-based Study of 42,722 Patients | 2008 |
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Professor James Allan
| The Genetics of Cancer Survivorship | 2008 |
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Professor James Allan
| A common genetic variant in XPD associates with risk of 5q- and 7q-deleted acute myeloid leukemia | 2007 |
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Professor James Allan
| Deregulation of homologous recombination DNA repair in alkylating agent-treatedstem cell clones: a possible role in the aetiology of chemotherapy-induced leukaemia | 2006 |
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Professor James Allan
| Mechanisms of therapy-related carcinogenesis | 2005 |
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Professor James Allan
| Genetic variation in XPD predicts treatment outcome and risk of acute myeloid leukemia following chemotherapy | 2004 |
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Professor James Allan
| An Intron Splice Acceptor Polymorphism in hMSH2 and Risk of Leukemia after Treatment with Chemotherapeutic Alkylating Agents | 2003 |
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Professor James Allan
| Genetic alterations in bronchial mucosa and plasma DNA from individuals at high risk of lung cancer | 2001 |
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Professor James Allan Professor Anthony Moorman
| Polymorphism in glutathione S-transferase PI is associated with susceptibility to chemotherapy-induced leukaemia | 2001 |
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