Publications by Professor Alison Tyson-Capper - ePrints

Browsing publications by Professor Alison Tyson-Capper.

Newcastle Authors	Title	Year
Shannon Jamieson Amy Mawdesley Dr Philip Hyde Emeritus Professor John Kirby Professor Alison Tyson-Capper et al.	Activation of Osteoblasts by Cobalt-Chromium Occurs Via a TLR4-Mediated Pathway	2022
Shannon Jamieson Dr Sami Anjum Josh Kirby Professor Alison Tyson-Capper	Ceramic Biomaterials: what are their biological implications?	2021
Vic Hart Dr Hannah Gautrey Josh Kirby Professor Alison Tyson-Capper	HER2 splice variants in breast cancer: their impact on diagnosis and treatment outcomes	2021
Vic Hart Marco Silipo Swapna Satam Dr Hannah Gautrey Emeritus Professor John Kirby et al.	HER2-PI9 and HER2-I12: two novel and functionally active splice variants of the oncogene HER2 in breast cancer	2021
Shannon Jamieson Amy Mawdesley Professor David Deehan Emeritus Professor John Kirby Professor Alison Tyson-Capper et al.	Inflammatory responses to metal oxide ceramic nanopowders	2021
Shannon Jamieson Professor Alison Tyson-Capper Dr Philip Hyde Emeritus Professor John Kirby	Understanding the immunobiology of orthopaedic biomaterials	2021
Amy Mawdesley Dr Sami Anjum Emeritus Professor John Kirby Professor Alison Tyson-Capper	Effect of cobalt ions on chemokine expression: Case report of immune cell infiltration in patient undergoing replacement of a metal-on-metal implant	2020
Anna Stanton Dr Catherine Mowbray Marcelo Lanz Dr Karen Brown Paul Hilton et al.	Topical Estrogen Treatment Augments the Vaginal Response to Escherichia coli Flagellin	2020
Dr Richard Hetherington Professor Alison Tyson-Capper	Research led teaching to Teaching led Research	2019
Professor Alison Tyson-Capper Dr Hannah Gautrey	Regulation of Mcl-1 alternative splicing by hnRNP F, H1 and K in breast cancer cells	2018
Dr Marina Danilenko Caroline Dalgliesh Dr Ingrid Ehrmann Professor Alison Tyson-Capper Dr Gavin Clowry et al.	Binding site density enables paralog-specific activity of SLM2 and Sam68 proteins in Neurexin2 AS4 splicing control	2017
Marco Silipo Dr Hannah Gautrey Swapna Satam Professor Tom Lennard Professor Alison Tyson-Capper et al.	How is Herstatin, a tumor suppressor splice variant of the oncogene HER2, regulated?	2017
Ased Ali Dr Catherine Mowbray Marcelo Lanz Anna Stanton Paul Hilton et al.	Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection	2017
Dr Helen Lawrence Professor David Deehan James Holland Dr Sami Anjum Amy Mawdesley et al.	Cobalt ions recruit inflammatory cells in vitro through human Toll-like receptor 4	2016
Dr Sami Anjum Dr Helen Lawrence James Holland Emeritus Professor John Kirby Professor David Deehan et al.	Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells	2016
Dr Helen Lawrence Amy Mawdesley James Holland Emeritus Professor John Kirby Professor David Deehan et al.	Targeting Toll-like receptor 4 prevents cobalt-mediated inflammation	2016
Dr Andrew Best Dr Katherine James Gerald Hysenaj Professor Alison Tyson-Capper Professor David Elliott et al.	Transformer2 proteins protect breast cancer cells from accumulating replication stress by ensuring productive splicing of checkpoint kinase 1	2016
Marco Silipo Dr Hannah Gautrey Professor Alison Tyson-Capper	Deregulation of splicing factors and breast cancer development	2015
Dr Gareth Waring Dr Judith Bulmer Professor Steve Robson Professor Alison Tyson-Capper	Inflammatory Signalling in Fetal Membranes: Increased Expression Levels of TLR 1 in the Presence of Preterm Histological Chorioamnionitis	2015
Dr Hannah Gautrey Anna-Lena Dittrich Professor Thomas Lennard Professor Alison Tyson-Capper	SRSF3 and hnRNP H1 regulate a splicing hotspot of HER2 in breast cancer cells	2015
Elaine Hong Dr Andrew Best Dr Hannah Gautrey Professor David Elliott Professor Alison Tyson-Capper et al.	Unravelling the RNA-Binding Properties of SAFB Proteins in Breast Cancer Cells	2015
Dr Helen Lawrence Professor David Deehan James Holland Emeritus Professor John Kirby Professor Alison Tyson-Capper et al.	Can cobalt from metal-on-metal joints activate human TLR4 and cause an inflammatory response?	2014
Andy Best Caroline Dalgliesh Elaine Hong Mahsa Kheirollahi Kouhestani Dr Yaobo Xu et al.	Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons	2014
Professor Janet Eyre Ian Harvey Professor Thomas Lennard Professor Alison Tyson-Capper Dr Annette Meeson et al.	Reversing paclitaxel resistance in ovarian cancer cells via inhibition of the ABCB1 expressing side population	2014
Anna-Lena Dittrich Dr Hannah Gautrey Professor Alison Tyson-Capper	The HER2 Signaling Network in Breast Cancer-Like a Spider in its Web	2014
Dr Helen Lawrence Professor David Deehan Emeritus Professor John Kirby Professor Alison Tyson-Capper	The immunobiology of cobalt: demonstration of a potential aetiology for inflammatory pseudotumours after metal-on-metal replacement of the hip	2014
Dr Andrew Best Caroline Dalgliesh Mahsa Kheirollahi Kouhestani Dr Marina Danilenko Dr Ingrid Ehrmann et al.	Tra2 protein biology and mechanisms of splicing control	2014
Dr Hannah Gautrey Professor Alison Tyson-Capper	Clinical significance of HER-2 splice variants in breast cancer progression and drug resistance	2013
Emeritus Professor Nick Europe-Finner Professor Alison Tyson-Capper	Estrogen Alters the Splicing of Type 1 Corticotropin-Releasing Hormone Receptor in Breast Cancer Cells	2013
Andy Best Dr Ingrid Ehrmann Mahsa Kheirollahi Kouhestani Professor Alison Tyson-Capper Professor David Elliott et al.	Expression of Tra2ß in cancer cells as a potential contributory factor to neoplasia and metastasis	2013
Dr Gareth Waring Professor Steve Robson Dr Judith Bulmer Professor Alison Tyson-Capper	Inflammatory signalling in fetal membranes: the transcriptome of chorioamnionitis	2013
Dr Gareth Waring Professor Steve Robson Dr Judith Bulmer Professor Alison Tyson-Capper	Inflammatory Signalling in Fetal Membranes: The Transcriptome of Chorioamnionitis	2013
Dr Gareth Waring Professor Steve Robson Dr Judith Bulmer Professor Alison Tyson-Capper	Inflammatory signalling in fetal membranes: the transcriptome of chorioamnionitis	2013
Professor Alison Tyson-Capper Dr Helen Lawrence James Holland Professor David Deehan Emeritus Professor John Kirby et al.	Metal-on-metal hips: cobalt can induce an endotoxin-like response	2013
David Cork Professor Steve Robson Dr Julian Venables Professor Alison Tyson-Capper	Myometrial-Specific Spatiotemporal Splicing Patterns in Pregnancy	2013
Dr David Cork Professor Steve Robson Dr Julian Venables Professor Alison Tyson-Capper	Myometrial-specific spatiotemporal splicing patterns in pregnancy	2013
Professor Alison Tyson-Capper Dr Helen Lawrence James Holland Professor David Deehan Emeritus Professor John Kirby et al.	The Molecular Mechanism of Cell Activation by Cobalt Ions. Comment on Ninomiya et al.: Metal Ions Activate Vascular Endothelial Cells and Increase Lymphocyte Chemotaxis and Binding	2013
Dr Elaine Hong Professor David Elliott Professor Alison Tyson-Capper	Identification of SAFB1 and SAFB2 Target Genes within the Oestrogen Receptor-Signalling Pathway in Breast Cancer Cells	2012
Dr Amena Shelleh Emeritus Professor John Kirby Professor Steve Robson Professor Alison Tyson-Capper	Preterm Birth: A Modulatory Role for HMGB1?	2012
Dr David Cork Emeritus Professor Tom Lennard Professor Alison Tyson-Capper	Progesterone receptor (PR) variants exist in breast cancer cells characterised as PR negative	2012
Dr David Cork Professor Thomas Lennard Professor Alison Tyson-Capper	Progesterone receptor (PR) variants exist in breast cancer cells characterised as PR negative	2012
Dr Hannah Gautrey Professor Alison Tyson-Capper	Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells	2012
Elaine Hong Dr Hannah Gautrey Professor David Elliott Professor Alison Tyson-Capper	SAFB1 and SAFB2 mediated transcriptional repression: relevance in cancer	2012
Dr David Cork Professor Thomas Lennard Professor Alison Tyson-Capper	The Functional Impact of Progesterone Receptor Alternative Splicing in Breast Cancer Cells	2012
Professor Alison Tyson-Capper Dr Kelly Britton Professor Steve Robson Dr Annette Meeson	The temporal and spatial expression patterns of ABCG2 in the developing human heart	2012
Dr Farah Sethna Professor Alison Tyson-Capper Liz Shiells Professor Steve Robson	The expression of glucocorticoid receptor in human myometrium in pregnancy and labour	2011
Professor Alison Tyson-Capper Qi Zhang Professor Steve Robson	Anti-Inflammatory Action of Progesterone on TLR-4 and COX-2 Activation Is Not Mediated by Nuclear Progesterone Receptors	2010
Emeritus Professor John Kirby Liz Shiells Professor Steve Robson Professor Alison Tyson-Capper	Characterisation of HMGB1 in the Human Myometrium during Pregnancy	2010
Professor Alison Tyson-Capper	Effect of Oestrogen on RNA-Binding Splicing Regulators in Breast Cancer Cells	2010
David Cork Professor Thomas Lennard Professor Alison Tyson-Capper	Hormone Responsive Expression of Naturally Occurring Truncated Progesterone Receptor Variants in Breast Cancer Cell Lines	2009
Professor Alison Tyson-Capper Liz Shiells Professor Steve Robson	Interplay between polypyrimidine tract binding protein-associated splicing factor and human myometrial progesterone receptors	2009
Professor Alison Tyson-Capper Liz Shiells Professor Steve Robson	Myometrial Progesterone Receptors at Term and in Labour: The Story Continues	2009
Kelly Harper Professor Steve Robson Emeritus Professor Nick Europe-Finner Professor Alison Tyson-Capper	Acetylation and phosphorylation status of HDACS and the epigenetics of myometrial quiescent and pro-contractile genes	2008
Dr Marie Smith Professor Alison Tyson-Capper Professor Steve Robson	Alternative signalling pathways contribute towards mediation of anti-inflammatory properties of progestins	2008
Dr David Cork Professor Thomas Lennard Professor Alison Tyson-Capper	Alternative splicing and the progresterone receptor in breast cancer	2008
Kelly Harper Professor Alison Tyson-Capper	Complexity of COX-2 gene regulation	2008
Dr Farah Sethna Professor Alison Tyson-Capper Liz Shiells Professor Steve Robson	Expression of glueocorticoid receptor in human myometrium during pregnancy and labour	2008
Liz Shiells Professor Steve Robson Professor Alison Tyson-Capper	Progesterone and progesterone receptor c in human myometrial and amnion derived WISH cells	2008
Professor Alison Tyson-Capper Professor Steve Robson	Progestins and the glucocorticoid receptor in human myometrial and amnion-derived WISH cells	2008
Professor Alison Tyson-Capper Liz Shiells Professor Steve Robson	The ambiguity of myometrial progesterone receptor expression in pregnancy and labour	2008
Professor Alison Tyson-Capper	Alternative splicing: An important mechanism for myometrial gene regulation that can be manipulated to target specific genes associated with preterm labour	2007
Professor Alison Tyson-Capper Dr David Cork Liz Shiells Andrew Loughney	Characterization of cellular retinoid-binding proteins in human myometrium during pregnancy	2006
Professor Alison Tyson-Capper Emeritus Professor Nick Europe-Finner	Novel targeting of COX-2 pre-mRNA using antisense morpholino oligonucleotides: suppression of Cox-2 activity in human myometrial cells and amnion-derived WISH cells	2006
Professor Alison Tyson-Capper Emeritus Professor Nick Europe-Finner	Novel targeting of COX-2 pre-mRNA using antisense morpholino oligonucleotides: Suppression of COX-2 activity in human myometrial cells and amnion-derived wish cells.	2006
Professor Alison Tyson-Capper Emeritus Professor Nick Europe-Finner	Novel targeting of cyclooxygenase-2 (COX-2) pre-mRNA using antisense morpholino oligonucleotides directed to the 3′ acceptor and 5′ donor splice sites of exon 4: Suppression of COX-2 activity in human amnion-derived WISH and myometrial cells	2006
Professor Alison Tyson-Capper Dr David Cork Elizabeth Kokkinos Emeritus Professor Nick Europe-Finner Andrew Loughney et al.	The role of the retinoids in the differentiation of the myometrium during pregnancy	2006
Dr Magdalena Karolczak-Bayatti Professor Alison Tyson-Capper Professor Steve Robson Emeritus Professor Nick Europe-Finner	Transcriptional regulation of the protein kinase a regulatory subunit II alpha (RIIalpha PKA) in the myometrium.	2006
Dr Jarrod Bailey Professor Alison Tyson-Capper Kate Gilmore Professor Steve Robson Emeritus Professor Nick Europe-Finner et al.	Identification of human myometrial target genes of the cAMP pathway: The role of cAMP-response element binding (CREB) and modulator (CREMα and CREMτ2α) proteins	2005
Dr Robert Phillips Professor Alison Tyson-Capper Dr Jarrod Bailey Professor Steve Robson Emeritus Professor Nick Europe-Finner et al.	Regulation of expression of the chorionic gonadotropin/luteinizing hormone receptor gene in the human myometrium: Involvement of specificity protein-1 (Sp1), Sp3,Sp4, Sp-like proteins, and histone deacetylases	2005
Professor Alison Tyson-Capper Dr Jarrod Bailey Professor Steve Robson Emeritus Professor Nick Europe-Finner	The switch in alternative splicing of cyclic AMP-response element modulator protein CREMτ2α (activator) to CREMα (repressor) in human myometrial cells is mediated by SRp40	2005
Professor Alison Tyson-Capper Professor Steve Robson Emeritus Professor Nick Europe-Finner	Alternative splicing of the adenylyl cyclase stimulatory G-protein Gαs is regulated by SF2/ASF and heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) and involves the use of an unusual TG 3′-splice site	2002
Dr Jarrod Bailey Dr Robert Phillips Professor Alison Tyson-Capper Kate Gilmore Professor Steve Robson et al.	Characterization and functional analysis of cAMP response element modulator protein and activating transcription factor 2 (ATF2) isoforms in the human myometrium during pregnancy and labor: Identification of a novel ATF2 species with potent transactivation properties	2002
Professor Alison Tyson-Capper Professor Steve Robson Emeritus Professor Nick Europe-Finner	Spatio-temporal expression of the Trans-acting splicing factors SF2/ASF and heterogeneous ribonuclear proteins A1/A1B in the myometrium of the pregnant human uterus: A molecular mechanism for regulating regional protein isoform expression in Vivo	2000