Publications by Marian Case - ePrints

Browsing publications by Marian Case.

Newcastle Authors	Title	Year
Dr Dino Masic Kayleigh Fee Dr Hayden Bell Marian Case Juan Ojeda Garcia et al.	Hyperactive CREB subpopulations increase during therapy in pediatric B-lineage acute lymphoblastic leukemia	2023
Marian Case Dr Dino Masic Dr David Jamieson Dr Frederik van Delft Professor Andrew Filby et al.	Label-Free Leukemia Monitoring by Computer Vision	2020
Liz Matheson Huw Thomas Marian Case Dr Helen Blair Rosanna Jackson et al.	Glucocorticoids and selumetinib are highly synergistic in RAS pathway mutated childhood acute lymphoblastic leukemia through upregulation of BIM	2019
Dr Paul Sinclair Dr Sarra Ryan Dr Matthew Bashton Shaun Hollern Rebecca Hanna et al.	SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain	2019
Dr Britta Vormoor Professor Gareth Veal Melanie Griffin Professor Julie Irving Lynne Minto et al.	A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia	2017
Judith Weiland Dr Deepali Pal Marian Case Professor Julie Irving Dr Frida Ponthan et al.	BCP-ALL blasts are not dependent on CD19 expression for leukaemic maintenance	2016
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Christopher Keilty Maryna Sanichar et al.	Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition	2015
Professor Julie Irving Elizabeth Matheson Helen Blair Marian Case Isabella Swidenbank et al.	Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. Blood. 2014;124(23):3420-3430	2015
Professor Julie Irving Elizabeth Matheson Dr Helen Blair Marian Case Isabella Swidenbank et al.	Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition	2014
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Marian Case Maryna Sanichar et al.	Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia	2012
Sarina Sulong Professor Anthony Moorman Professor Julie Irving Marian Case Professor Simon Bailey et al.	A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups	2009
Professor Julie Irving Marian Case Lynne Minto Sally Lawson	Establishment and validation of a standard protocol for the detection of minimal residual disease in B lineage childhood acute lymphoblastic leukemia by flow cytometry in a multi-center setting	2009
Kate Wilson Marian Case Lynne Minto Professor Simon Bailey Dr Nicholas Bown et al.	Flow minimal residue disease monitoring of candidate leukemic stem cells defined by the immunophenotype, CD34⁺CD38^lowCD19⁺ in B-lineage childhoood acute lymphoblastic leukemia	2009
Kerrie Wilson Dr Klaus Rehe Dr Simon Bomken Marian Case Professor Julie Irving et al.	In Childhood ALL, Both Blasts with a CD20(-/Low) and a CD20(High) Immunophenotype, Have the Ability to Transfer the Leukemia Onto Immune-Deficient NOD/Scid Y-/- Mice	2008
Professor Anthony Moorman Sarina Sulong Professor Julie Irving Marian Case Lynne Minto et al.	Inactivation of CDKN2A in childhood acute lymphoblastic leukaemia (ALL) occurs principally by deletion and is strongly correlated with cytogenetic subgroups	2008
Marian Case Elizabeth Matheson Lynne Minto Dr Nicholas Bown Professor Simon Bailey et al.	Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia	2008
Marian Case Elizabeth Matheson Lynne Minto Professor Christine Harrison FRCPath FMedSci Dr Nicholas Bown et al.	Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting	2008
Kerrie Wilson Marian Case Lynne Minto Professor Simon Bailey Professor Hermann Josef Vormoor et al.	The CD34⁺ CD38^Low CD19⁺ Candidate Leukemic Stem Cell Phenotype Revisited: Useful for Flow MRD Monitoring?	2008
Marian Case Dr Tina Davies Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al.	The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1	2008
Dr Linda Hogarth Dr Chris Redfern Dr Andrew Hall Dr Holly Anderson Marian Case et al.	The effect of thiopurine drugs on DNA methylation in relation to TPMT expression	2008
Elizabeth Matheson Dr Linda Hogarth Marian Case Professor Julie Irving Dr Andrew Hall et al.	DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo	2007
Professor Anthony Moorman Marian Case Professor Julie Irving Dr Andrew Hall Professor Christine Harrison FRCPath FMedSci et al.	Genomic profiling reveals multiple genetic targets in ETV6-RUNX1 positive acute lymphoblastic leukaemia (ALL)	2007
Dr Jane Carr-Wilkinson Dr Nicholas Bown Marian Case Dr Andrew Hall Professor John Lunec et al.	High-resolution analysis of allelic imbalance in neuroblastoma cell lines by single nucleotide polymorphism arrays	2007
Adillah Binti Yusof Professor Julie Irving Marian Case Lynne Minto Professor Christine Harrison FRCPath FMedSci et al.	Red blood cell alloimmunization is affected by depletion of donor white cell subsets	2007
Dr Andrew Hall Sarina Sulong Professor Christine Harrison FRCPath FMedSci Lynne Minto Dr Nicholas Bown et al.	Assessment of aneuploidy in childhood acute lymphoblastic leukaemia using high density oligonucleotide arrays.	2006
Sarina Sulong Professor Julie Irving Marian Case Lynne Minto Dr Nicholas Bown et al.	Comprehensive analysis of p16(INK4a) in childhood acute lymphoblastic leukemia reveals homozygous deletion, haploinsufficiency and acquired isodisomy at the 9p locus with intact p16(INK4a).	2006
Marian Case Dr Andrew Hall Dr Linda Hogarth Amanda Jones	Design, synthesis and initial in vitro evaluation of novel prodrugs for the treatment of cystinosis	2006
Mark Leslie Marian Case Dr Andrew Hall Dr Sally Coulthard	Expression levels of asparagine synthetase in blasts from children and adults with acute lymphoblastic leukaemia	2006
Professor Julie Irving Lynne Minto Elizabeth Matheson Marian Case Professor Simon Bailey et al.	Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse.	2006
Professor Julie Irving Clare Bloodworth Dr Nicholas Bown Marian Case Dr Linda Hogarth et al.	Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis	2005
Sarina Sulong Marian Case Lynne Minto Dr Bridget Wilkins Dr Andrew Hall et al.	The V617F mutation in Jak2 is not found in childhood acute lymphoblastic leukaemia	2005
Mark Leslie Marian Case Dr Andrew Hall Dr Sally Coulthard	Potential use of asparagine synthetase levels in the individualisation of L-asparaginase therapy	2003
Mark Leslie Marian Case Dr Andrew Hall Dr Sally Coulthard	Measurement of aspargine synthetase mRNA levels by real-time PCR	2001
Marian Case Dr Andrew Hall	Glutathione homeostasis in buthionine sulfoximine sensitive and resistant neuroblastoma cell lines	2000
Marian Case Professor Alastair Burt Joan Hughes Dr Jeremy Palmer Professor Margaret Bassendine et al.	Erratum to 'Enhanced ultrasensitive detection of structurally diverse antigens using a single immuno-PCR assay protocol' (Journal of Immunological Methods (1999) 223 (93-106))	1999
Dr Glenn Major Sarah Jane Ross Marian Case	Evidence for autoproteolysis of substrate-inactivated O-6-methylguanine-DNA methyltransferase following DNA repair	1999