Publications by Professor John Robinson - ePrints

Browsing publications by Professor John Robinson.

Newcastle Authors	Title	Year
Dr Julie Musson Professor John Robinson	CD4+T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor	2016
Professor John Robinson	Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokines	2015
Dr Julie Musson Professor John Robinson	T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute Melioidosis	2015
Dr Caroline Wilson Dr Lindsay Murphy Jack Leslie Dr Stuart Kendrick Jeremy French et al.	Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease	2015
Dr Julie Musson Professor John Robinson	Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4⁺T cell immunity	2014
Dr Marzena Ciechomska Dr Caroline Wilson Achilleas FLOUDAS Emeritus Professor Drew Rowan Professor John Robinson et al.	Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4⁺ T-cell activation	2014
Dr Julie Musson Professor Anthony De Soyza Professor John Robinson	CD4⁺ T Cell Epitopes of FliC Conserved between Strains of Burkholderia: Implications for Vaccines against Melioidosis and Cepacia Complex in Cystic Fibrosis	2014
Dr Andreas Werner Dr Simon Cockell Dr Jane Falconer Mark Carlile Dr Sammer Alnumeir et al.	Contribution of natural antisense transcription to an endogenous siRNA signature in human cells	2014
Dr Jane Falconer Katie Lowes Professor Fai Ng Professor John Robinson	Intramolecular polyspecificity in CD4 T-cell recognition of A^d-restricted epitopes of proteoglycan aggrecan	2014
Dr Michael Gray Professor John Robinson Dr Jane Falconer	The role of cystic fibrosis transmembrane conductance regulator in antigen processing and presentation to CD4+T-cells	2014
Professor John Robinson	Exposure to anthrax toxin alters human leucocyte expression of anthrax toxin receptor 1	2013
Dr Marta Radwan Christos Gavriilidis Professor John Robinson Emeritus Professor Drew Rowan Professor David Young et al.	Matrix metalloproteinase-13 expression in response to double-stranded RNA in human chondrocytes	2013
Dr Jeroen Stoop Chris Tibbitt Professor John Robinson Professor Catharien Hilkens	The choice of adjuvant determines the cytokine profile of T cells in proteoglycan-induced arthritis but does not influence disease severity	2013
Professor John Robinson	Identification of immunodominant T cell epitopes from anthrax protective antigen for inclusion in a rationally designed sub-unit based vaccine	2012
Dr Marta Radwan Emeritus Professor Drew Rowan Professor John Robinson Emeritus Professor Tim Cawston Professor David Young et al.	Involvement of pattern recognition receptors in poly(I:C)-mediated MMP-13 expression	2012
Dominic Hine Ariel Pradipta Professor Jeffrey Pearson Professor John Robinson Dr Andrew Knight et al.	Presentation of the candidate rheumatoid arthritis autoantigen aggrecan by antigen-specific B cells induces enhanced CD4+T helper type 1 subset differentiation	2012
Dr Marzena Ciechomska Dr Caroline Wilson Emeritus Professor Drew Rowan Professor John Robinson Dr Andrew Knight et al.	Antigen-specific B cells can acquire and present the rheumatoid arthritis candidate autoantigen aggrecan from a non-internalisable surface	2011
Dr Jeroen Stoop Professor John Robinson Professor Catharien Hilkens	Developing tolerogenic dendritic cell therapy for rheumatoid arthritis: what can we learn from mouse models?	2011
Dr Marta Radwan Emeritus Professor Drew Rowan Professor John Robinson Emeritus Professor Tim Cawston Professor David Young et al.	Pattern recognition receptors in osteoarthritic cartilage	2011
Dr Marzena Ciechomska Dr Caroline Wilson Emeritus Professor Drew Rowan Professor John Robinson Dr Andrew Knight et al.	Examination of the ability of autoreactive B cells to acquire and present the rheumatoid arthritis candidate autoantigen, aggrecan, from a non-internalizable surface	2010
Harriet Purvis Dr Jeroen Stoop Professor Jelena Mann Steven Woods Anne Kozijn et al.	Low strength T-cell activation promotes Th17 responses	2010
Dr Jeroen Stoop Professor Jelena Mann Steven Woods Anne Kozijn Professor Sophie Hambleton et al.	Low-strength T-cell activation promotes Th17 responses	2010
Professor John Robinson	Natural Exposure to Cutaneous Anthrax Gives Long-Lasting T Cell Immunity Encompassing Infection-Specific Epitopes	2010
Professor John Robinson	Repertoire of HLA-DR1-Restricted CD4 T-Cell Responses to Capsular Caf1 Antigen of Yersinia pestis in Human Leukocyte Antigen Transgenic Mice	2010
Dr Alexei von Delwig James Locke Professor John Robinson Professor Fai Ng	Response of Th17 Cells to a Citrullinated Arthritogenic Aggrecan Peptide in Patients With Rheumatoid Arthritis	2010
Dr Jeroen Stoop Professor John Robinson Professor Catharien Hilkens	The choice of adjuvant determines the cytokine profile of T cells in proteoglycan induced arthritis	2010
Professor John Robinson Dr Andrew Knight	The role of B cells as antigen presenting cells in an animal model of rheumatoid arthritis	2010
Dr Jeroen Stoop Dr Rachel Harry Dr Alexei von Delwig Professor John Isaacs Professor John Robinson et al.	Therapeutic Effect of Tolerogenic Dendritic Cells in Established Collagen-Induced Arthritis Is Associated With a Reduction in Th17 Responses	2010
Professor John Robinson	Colony variability under the spotlight in animal models of arthritis	2009
Dr Caroline Wilson Professor John Robinson Dr Andrew Knight	Efficient processing and presentation of the Rheumatoid Arthritis candidate autoantigen aggrecan, by antigen-specific B cells	2009
Dr Amy Anderson Dr David Swan Bethan Sayers Dr Rachel Harry Dr Angela Patterson et al.	LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells	2009
Dr Alexei von Delwig James Locke Professor John Robinson Professor Fai Ng	T cell responses to citrullinated aggrecan peptide in rheumatoid arthritis	2009
Jane Falconer Professor Fai Ng Professor John Robinson	Type A and type B T cell recognition of an arthritogenic CD4 T cell epitope from proteoglycan aggrecan studied in mice	2009
Professor John Robinson Dr Andrew Knight	A comparison of autoantigen processing by B cells, macrophages and dendritic cells	2008
Dr Jane Falconer Professor John Robinson	Degeneracy in CD4 T cell recognition of proteoglycan aggrecan in mice	2008
Dr Gary Litherland Dr Matthew Barter Emeritus Professor Tim Cawston Professor John Robinson Emeritus Professor Drew Rowan et al.	Differential Toll-like receptor-dependent collagenase expression in chondrocytes	2008
Dr Jane Falconer Divya Venkatesh Professor John Robinson	Fine specificity of type A and type B T-cell recognition of an arthritogenic CD4 T-cell epitope from proteoglycan aggrecan in BALB/c mice	2008
Dr Jeroen Stoop Dr Alexei von Delwig Professor John Isaacs Professor John Robinson Professor Catharien Hilkens et al.	Immunotherapy with tolerogenic dendritic cells inhibits the progression of collagen-induced arthritis	2008
Professor John Robinson	John Leyden’s Lyra Viol Manuscript in Newcastle University Library and George Farquhar Graham’s Copy in the National Library of Scotland	2008
Professor John Robinson	Pillars of Immunology article: Generation of T-cell Function in Organ Culture of Foetal Mouse Thymus. I. Mitogen Responsiveness	2008
Dr Jane Falconer Dr Jenny Milner Professor John Robinson	The role of metallo-proteinases in processing of the candidate joint autoantigen proteoglycan aggrecan for presentation to CD4 T cells	2008
Dr Alexei von Delwig Dr Fraser Charlton Professor John Isaacs Professor John Robinson	T cell responses to a non-glycosylated epitope predominate in type II collagen-immunised HLA-DRB1*0101 transgenic mice	2007
Professor John Robinson	The fraction 1 and V protein antigens of Yersinia pestis activate dendritic cells to induce primary T cell responses	2007
Dr Alexei von Delwig Professor John Isaacs Professor Jeremy Lakey Professor John Robinson	Febrile temperatures enhance antigen processing of type II collagen for presentation to CD4 T cells.	2006
Dr David Allen Chalton Dr Heather Lamb Professor John Robinson Professor Jeremy Lakey	Immunogenicity of a Yersinia pestis vaccine antigen monomerized by circular permutation	2006
Dr Alexei von Delwig Professor Catharien Hilkens Professor John Isaacs Dr Helen Robertson Professor John Robinson et al.	Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice	2006
Dr Helen Harper Dr Alexei von Delwig Professor John Robinson	Mechanisms of major histocompatibility complex class II-restricted processing and presentation of the V antigen of Yersinia pestis	2006
Dr Julie Musson Dr Helen Harper Professor John Robinson	Sequential proteolytic processing of the capsular Caf1 antigen of Yersinia pestis for major histocompatibility complex class II-restricted presentation to T lymphocytes	2006
Dr Alexei von Delwig Professor John Isaacs Dr Norman Balfour-McKie Professor John Robinson	The impact of glycosylation on HLA-DR1-restricted T cell recognition of type II collagen in a mouse model	2006
Professor John Robinson	A description of the Medici Lute Manuscript (MS II.C.23) in the Dolmetsch Library, and a summary of modern studies	2005
Katie Lowes Dr Alexei von Delwig Emeritus Professor Drew Rowan Professor John Robinson	CD4 T cells cross-react between several arthritogenic epitopes of aggrecan in BALB/c mice	2005
Dr Alexei von Delwig Dr Julie Musson Dr Jeong-Jin Lee Professor John Robinson	Distribution of productive antigen-processing activity for MHC class II presentation in macrophages	2005
Dr Sanj Ugrinovic Professor Colin Brooks Professor Carlos Hormaeche Professor John Robinson	H2-M3 major histocompatibility complex class Ib-restricted CD8 T cells induced by Salmonella enterica serovar typhimurium infection recognize proteins released by Salmonella serovar typhimurium	2005
Dr Alexei von Delwig Professor John Isaacs Professor John Robinson	Human type II collagen is processed in lysosomal compartments of macrophages for presentation of the glycosylated arthritogenic epitope hCII(259-273) to CD4 T cells in HLA-DR1 transgenic mice	2005
Dr Alexei von Delwig Dr Julie Musson Dr Joseph Gray Dr Norman Balfour-McKie Professor John Robinson et al.	Major histocompatibility class II molecules prevent destructive processing of exogenous peptides at the cell surface of macrophages for presentation to CD4 T cells	2005
Dr Alexei von Delwig Dr Julie Musson Ho-Ki Shim Christopher Harding Professor John Robinson et al.	Non-lysosomal compartments of macrophages participate in antigen processing for presentation by mature MHC class II molecules	2005
Katie Lowes Dr Alexei von Delwig Professor Judith Goodship Emeritus Professor Drew Rowan Professor John Robinson et al.	Specificity of CD4 T cell responses to aggrecan in BALB/c and DR1 transgenic mice	2005
Katie Lowes Dr Alexei von Delwig Emeritus Professor Drew Rowan Professor John Robinson	Specificity of CD4 T-cell responses to aggrecan in BALB/c and DR1 transgenic mice	2005
Dr Alexei von Delwig Professor John Isaacs Professor John Robinson	The role of uptake and intracellular trafficking of type II collagen in presentation of the glycosylated arthritogenic epitope CII259-273, to CD4 T cells in HLA-DR1 transgenic mice	2005
Dr Mbithe Mutunga Dr Julie Musson Professor John Robinson Dr Anjam Khan Professor Carlos Hormaeche et al.	Attenuated Salmonella typhimurium htrA mutants cause fatal infections in mice deficient in NADPH oxidase and destroy NADPH oxidase-deficient macrophage monolayers	2004
Professor John Robinson	Cellular and molecular foundations of presentation of antigens	2004
Dr Simon Bridge Professor John Robinson	Differential efficacy of vaccinia virus envelope proteins administered by DNA immunisation in protection of BALB/c mice from a lethal intranasal poxvirus challenge	2004
Dr Alexei von Delwig Professor John Isaacs Professor John Robinson	Mechanisms of MHC class II-restricted antigen processing and presentation of human type II collagen in antigen-presenting cells from humanized DR1 transgenic mice	2004
Dr Julie Musson Professor John Robinson	Differential Processing of CD4 T-cell Epitopes from the Protective Antigen of Bacillus anthracis	2003
Dr Alexei von Delwig Professor John Robinson	Localization of peptide/MHC class II complexes in macrophages following antigen processing of viable Streptococcus pyogenes	2003
Dr Alexei von Delwig Dr Julie Musson Dr Norman Balfour-McKie Dr Joseph Gray Professor John Robinson et al.	Regulation of peptide presentation by major histocompatibility complex class II molecules at the surface of macrophages	2003
Professor John Robinson	Uptake of the Protective Antigen of Bacillus anthracis for MHC class II-restricted antigen presentation to T cells	2003
Dr Julie Musson Professor John Robinson Dr Andreas Werner	A novel isoform of the Shank adaptor protein family (Shank 3b) is expressed in immune cells and colocalizes with actin	2002
Professor John Robinson Dr Alexei von Delwig	Diversity in mhc class ii antigen presentation	2002
Karen Fraser Frances Davison Professor John Robinson Professor Colin Brooks	NK cells developing in vitro from fetal mouse progenitors express at least one member of the Ly49 family that is acquired in a time-dependent and stochastic manner independently of CD94 and NKG2	2002
Dr Julie Musson Dr Alexei von Delwig Professor Carlos Hormaeche Professor John Robinson	Processing of viable Salmonella typhimurium for presentation of a CD4 T cell epitope from the Salmonella invasion protein C (SipC)	2002
Dr Jeong-Jin Lee Professor Michael Kehoe Professor John Robinson	Structural and functional role of threonine 112 in a superantigen Staphylococcus aureus enterotoxin B	2002
Dr Alexei von Delwig Dr Jeong-Jin Lee Professor Zofia Chrzanowska-Lightowlers Professor John Robinson	TGF-β1 and IFN-γ cross-regulate antigen presentation to CD4 T cells by macrophages	2002
Dr Alexei von Delwig Professor John Robinson	The route of bacterial uptake by macrophages influences the repertoire of epitopes presented to CD4 T cells	2002
Professor John Robinson	CD4 T-cell epitope mapping	2001
Professor John Robinson	Testing meningococcal vaccines for mitogenicity and superantigenicity	2001
Professor John Robinson	Neisseria meningitidis: From the antigenic structure to new generation vaccines	2000
Dr Alexei von Delwig Professor John Robinson	The role of calcium homeostasis and flux during bacterial antigen processing in murine macrophages	1999
Dr Alexei von Delwig Professor John Robinson	Different endosomal proteolysis requirements for antigen processing of two T-cell epitopes of the M5 protein from viable Streptococcus pyogenes	1998
Professor Andrew Gennery Professor John Robinson Dr Gavin Spickett Professor Andrew Cant	Immunological studies on children with the 22q11 deletion syndrome	1998
Dr Julia Harrison Professor John Robinson Professor Carlos Hormaeche	Interleukin-12 is required for control of the growth of attenuated aromatic-compound-dependent salmonellae in BALB/c mice: Role of gamma interferon and macrophage activation	1998
Professor John Robinson	Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages	1998
Professor John Robinson	Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells	1998
Professor John Robinson	Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells	1998
Dr Alexei von Delwig Professor John Robinson	Two T cell epitopes from the M5 protein of viable Streptococcus pyogenes engage different pathways of bacterial antigen processing in mouse macrophages	1998
Dr Beverley Degnan Professor John Robinson Professor Michael Kehoe	Streptococcus pyogenes type 5 M protein is an antigen, not a superantigen, for human T cells	1997
Dr Alexei von Delwig Professor John Robinson	T-cell epitope mapping the PorB protein of serogroup B Neisseria meningitidis in B10 congenic strains of mice	1997
Emeritus Professor Reg Jordan Professor John Robinson	Thymic epithelium and the induction of transplantation tolerance in nude mice	1985
Professor John Robinson	The ontogeny of antigen presenting cells in fetal thymus evaluated by MLR stimulation	1983
Professor John Robinson Emeritus Professor Reg Jordan	Thymus in vitro	1983
Professor John Robinson	Transplantation tolerance induced in foetal mouse thymus in vitro	1978
Professor John Robinson	Generation of T cell function in organ culture of foetal mouse thymus. II. Mixed lymphocyte culture reactivity	1977
Professor John Robinson	A comparison of four methods for measuring cutaneous delayed type hypersensitivity reactions to protein antigens in mice	1976
Professor John Robinson	Generation of T cell function in organ culture of foetal mouse thymus I. Mitogen responsiveness	1976