Publications by Dr Andrew Hall - ePrints

Browsing publications by Dr Andrew Hall.

Newcastle Authors	Title	Year
Dr Carmela Ciardullo Dr Katarzyna Szoltysek Dr Peixun Zhou Dr Elaine Willmore Dr Amir Enshaei et al.	Low BACH2 expression predicts adverse outcome in chronic lymphocytic leukaemia	2022
Dr Katarzyna Szoltysek Dr Carmela Ciardullo Dr Peixun Zhou Dr Anna Walaszczyk Dr Elaine Willmore et al.	Dap kinase-related apoptosis-inducing protein kinase 2 (Drak2) is a key regulator and molecular marker in chronic lymphocytic leukemia	2020
Dr Peixun Zhou Dr Alex Blain Alex Newman Dr Masood Zaka Dr Ugo Offor et al.	Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif	2019
Dr Max Robinson Professor Philip Sloan Dr Andrew Hall	Training and accreditation standards for pathologists undertaking clinical trial work	2019
Dr Andrew Hall	Barriers to the release of human tissue for clinical trials research in the UK: A national survey of cellular pathology laboratories on behalf of the National Cancer Research Institute's Cellular Molecular Pathology (CM-Path) initiative	2018
Dr Peixun Zhou Alex Newman Filbert Adlar Casey Broadbent Dr Alison Blain et al.	Investigation of FOXO1 mutations in paediatric endemic and sporadic Burkitt lymphoma	2018
Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson Dr Helen Marr et al.	Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia	2017
Dr Carmela Ciardullo Dr Elaine Willmore Dr Amir Enshaei Dr Peixun Zhou Dr Vikki Rand et al.	BACH2 and BCL6 Cooperatively Fuction as Tumour Suppressors in CLL	2016
Dr Carmela Ciardullo Dr Elaine Willmore Dr Peixun Zhou Dr Vikki Rand Professor Christine Harrison FRCPath FMedSci et al.	Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia	2016
Dr Carmela Ciardullo Dr Peixun Zhou Dr Elaine Willmore Professor Christine Harrison FRCPath FMedSci Dr Andrew Hall et al.	Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia	2016
Alison Page Dr Ghada Malik Dr Andrew Hall Professor Deborah Tweddle	The National Children's Cancer and Leukaemia Group Tissue Bank similar to Facilitating a Comprehensive Range of Paediatric Oncology Research	2016
Katie Dormon Elda Latif Dr Matthew Bashton Dr Deepali Pal Dr Helen Blair et al.	A Whole Genome In Vivo Crispr Screen in Primary ALL Predicts Leukaemic Relapse	2015
Dr Nicola Sunter Dr Helen Marr Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson et al.	Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk	2015
Dr Linda Hogarth Dr Andrew Hall	p21^WAF1 modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia	2015
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Christopher Keilty Maryna Sanichar et al.	Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition	2015
Dr Jeyanthy Eswaran Dr Paul Sinclair Professor Olaf Heidenreich Professor Julie Irving Dr Lisa Russell et al.	The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia	2015
Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson Professor James Allan et al.	A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia	2014
Dr Vikki Rand Stephen Johnstone Dr Rachel Crossland Sarah Wilkinson Dr Andrew Hall et al.	The Genomic Landscape of Relapsed B-Cell Acute Lymphoblastic Leukaemia (B-ALL) in Adolescents and Adults	2014
Dr Vikki Rand Dr Andrew Hall	BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint	2013
Dr Klaus Rehe Kerrie Wilson Dr Simon Bomken Dr Daniel Williamson Professor Julie Irving et al.	Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations	2013
Dr Andrew Hall	BACH2 Is Required for Pre-B Cell Receptor Checkpoint Control and p53-Dependent Tumor Surveillance	2012
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Marian Case Maryna Sanichar et al.	Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia	2012
Michael Batey Dr Yan Zhao Dr Helen Maitland Professor Hing Leung Dr Andrew Hall et al.	Comparative pre-clinical evaluation of receptor tyrosine kinase inhibitors for the treatment of multiple myeloma	2011
Dr Sally Coulthard Dr Chris Redfern Svante Vikingsson Dr Malin Lindqvist Appell Dr Andrew Hall et al.	Increased Sensitivity to Thiopurines in Methylthioadenosine Phosphorylase-Deleted Cancers	2011
Dr Linda Hogarth Dr Andrew Hall	p53-independent Epigenetic Repression of the p21^WAF1 Gene in T-cell Acute Lymphoblastic Leukemia	2011
Haya AL-Balool Dr Mark Wade Dr Jonathan Coxhead Professor Julie Irving Professor David Elliott et al.	Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant	2011
Dr Lindsay Nicholson Charlotte Evans Elizabeth Matheson Lynne Minto Christopher Keilty et al.	Quantitative Proteomic Analysis Reveals Maturation As a Mechanism Underlying Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia and PAX5 As a Re-Sensitising Therapeutic Target	2011
Professor Graham Jackson Dr Nicola Sunter Dr Andrew Hall Professor Julie Irving Professor James Allan et al.	A polymorphism in the 3' UTR of IRF4 linked to susceptibility and pathogenesis in chronic lymphocytic leukaemia and Hodgkin lymphoma has limited impact in multiple myeloma	2010
Dr Amy Peasland Elizabeth Matheson Dr Andrew Hall Professor Julie Irving	Alternative splicing of hMLH1 in childhood acute lymphoblastic leukaemia and characterisation of the variably expressed Δ9/10 isoform as a dominant negative species	2010
Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson Professor James Allan et al.	Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk	2010
Elizabeth Matheson Lynne Minto Dr Andrew Hall Professor Julie Irving	Mismatch repair and the downstream target genes, PAX5 and Ikaros, in childhood acute lymphoblastic leukemia	2010
Dr Lindsay Nicholson Dr Andrew Hall Dr Chris Redfern Professor Julie Irving	NF kappa B modulators in a model of glucocorticoid resistant, childhood acute lymphoblastic leukemia	2010
Professor James Allan Dr Nicola Sunter Dr Andrew Hall Dr Christopher Bacon Jonathan Pointon et al.	Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia	2010
Sarina Sulong Professor Anthony Moorman Professor Julie Irving Marian Case Professor Simon Bailey et al.	A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups	2009
Dr Andrew Hall	Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms	2009
Dr Tevfik Dorak Professor Caroline Relton Professor Louise Parker Dr Andrew Hall	Hereditary Hemochromatosis Gene (HFE) Variants are Associated with Birth Weight and Childhood Leukemia Risk	2009
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Christopher Keilty Dr Andrew Hall et al.	Quantitative Proteomic Analysis Implicates An Altered B-Cell Differentiation State as a Mechanism Underlying GC-Resistance in An Acute Lymphoblastic Leukaemia (ALL) Cell Line Model	2009
Neil Johnson Professor Nicola Curtin Dr Andrew Hall	A comparative study of genome-wide SNP, CGH microarray and protein expression analysis to explore genotypic and phenotypic mechanisms of acquired antiestrogen resistance in breast cancer	2008
Professor James Allan Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson et al.	A Common Genetic Variant in the 3'UTR of IRF4/MUM1 Associates with Risk of Disease and Poor Prognosis in Chronic Lymphocytic Leukaemia	2008
Dr Nicola Sunter Dr Andrew Hall Dr Tryfonia Mainou-Fowler Professor Graham Jackson Professor James Allan et al.	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia	2008
Professor Julie Irving Lynne Minto Dr Andrew Hall	Genomic analysis of different clonal evolution in a twin pair with t(12;21) positive acute lymphoblastic leukemia sharing the same prenatal clone [8]	2008
Elizabeth Matheson Lynne Minto Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al.	Heterogeneous breakpoints target PAX5 in acute lymphoblastic leukaemia patients with dicentric chromosomes	2008
Michael Batey Dr Helen Maitland Professor Hing Leung Dr Andrew Hall Professor Graham Jackson et al.	In vitro activity of the multi targeted receptor tyrosine kinase inhibitor sunitinib against multiple myeloma cell lines is not predictive of in vivo xenograft response	2008
Professor Anthony Moorman Sarina Sulong Professor Julie Irving Marian Case Lynne Minto et al.	Inactivation of CDKN2A in childhood acute lymphoblastic leukaemia (ALL) occurs principally by deletion and is strongly correlated with cytogenetic subgroups	2008
Elizabeth Matheson Mike Cole Dr Bridget Wilkins Dr Andrew Hall	Mismatch repair defects in childhood acute lymphoblastic leukaemia at diagnosis and relapse	2008
Marian Case Elizabeth Matheson Lynne Minto Dr Nicholas Bown Professor Simon Bailey et al.	Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia	2008
Marian Case Elizabeth Matheson Lynne Minto Professor Christine Harrison FRCPath FMedSci Dr Nicholas Bown et al.	Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting	2008
Marian Case Dr Tina Davies Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al.	The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1	2008
Dr Linda Hogarth Dr Chris Redfern Dr Andrew Hall Dr Holly Anderson Marian Case et al.	The effect of thiopurine drugs on DNA methylation in relation to TPMT expression	2008
Elizabeth Matheson Professor Anthony Moorman Dr Andrew Hall Professor Christine Harrison FRCPath FMedSci Professor Julie Irving et al.	Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer	2008
Dr Andrew Hall	Acquired isodisomy is common in atypical myeloproliferative disorders	2007
Elizabeth Matheson Dr Linda Hogarth Marian Case Professor Julie Irving Dr Andrew Hall et al.	DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo	2007
Professor Anthony Moorman Marian Case Professor Julie Irving Dr Andrew Hall Professor Christine Harrison FRCPath FMedSci et al.	Genomic profiling reveals multiple genetic targets in ETV6-RUNX1 positive acute lymphoblastic leukaemia (ALL)	2007
Dr Jane Carr-Wilkinson Dr Nicholas Bown Marian Case Dr Andrew Hall Professor John Lunec et al.	High-resolution analysis of allelic imbalance in neuroblastoma cell lines by single nucleotide polymorphism arrays	2007
Dr Maria Lastowska Dr Mauro Santibanez Koref Ilka Wappler Dr Heiko Peters Dr Andrew Hall et al.	Identification of candidate genes involved in neuroblastoma progression by combining genomic and expression microarrays with survival data	2007
Adillah Binti Yusof Professor Julie Irving Marian Case Lynne Minto Professor Christine Harrison FRCPath FMedSci et al.	Red blood cell alloimmunization is affected by depletion of donor white cell subsets	2007
Elizabeth Matheson Lynne Minto Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al.	Variable Breakpoints Target PAX5 in Patients with Dicentric Chromosomes: A Model for the Basis of Unbalanced Translocations in Cancer	2007
Dr Andrew Hall Sarina Sulong Professor Christine Harrison FRCPath FMedSci Lynne Minto Dr Nicholas Bown et al.	Assessment of aneuploidy in childhood acute lymphoblastic leukaemia using high density oligonucleotide arrays.	2006
Dr Akheel Syed Professor Julie Irving Dr Chris Redfern Dr Andrew Hall Professor Nigel Unwin et al.	Association of glucocorticoid receptor polymorphism A3669G in exon 9β with reduced central adiposity in women	2006
Sarina Sulong Professor Julie Irving Marian Case Lynne Minto Dr Nicholas Bown et al.	Comprehensive analysis of p16(INK4a) in childhood acute lymphoblastic leukemia reveals homozygous deletion, haploinsufficiency and acquired isodisomy at the 9p locus with intact p16(INK4a).	2006
Marian Case Dr Andrew Hall Dr Linda Hogarth Amanda Jones	Design, synthesis and initial in vitro evaluation of novel prodrugs for the treatment of cystinosis	2006
Mark Leslie Marian Case Dr Andrew Hall Dr Sally Coulthard	Expression levels of asparagine synthetase in blasts from children and adults with acute lymphoblastic leukaemia	2006
Professor Julie Irving Lynne Minto Elizabeth Matheson Dr Lindsay Nicholson Dr Andrew Hall et al.	Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor	2006
Professor Julie Irving Lynne Minto Elizabeth Matheson Marian Case Professor Simon Bailey et al.	Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse.	2006
Diana Levett Professor Roderick Skinner Dr Andrew Hall Dr John Hanley	Novel mutations in a child with congenital amegakaryocytic thrombocytopenia	2006
Dr Andrew Hall Professor Julie Irving Lynne Minto	Reply to 'ATM variants and predisposition to childhood T-lineage acute lymphoblastic leukaemia' by Gumy-Pause et al. [6]	2006
Professor Nick Reynolds Dr Helen Anderson Gordon Taylor Dr Andrew Hall Dr Linda Hogarth et al.	Thioguanine nucleotide levels correlate with clinical response in atopic eczema patients treated with azathioprine	2006
Dr Simon Meggitt Professor Nick Reynolds Dr Helen Anderson Gordon Taylor Dr Andrew Hall et al.	Thioguanine nucleotides in patients with moderate-to-severe atopic eczema treated with azathioprine	2006
Professor Julie Irving Dr Andrew Hall	Constitutional segmental uniparental disomy in a twin pair with t(12;21) positive acute lymphoblastic leukemia characterized by the same prenatal clone and divergent clonal evolution	2005
Dr Mark Velangi Elizabeth Matheson Dr Andrew Hall Professor Julie Irving	Detecting mismatch repair defects in myeloma	2005
Professor Julie Irving Lynne Minto Professor Simon Bailey Dr Andrew Hall	Loss of heterozygosity and somatic mutations of the Glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course	2005
Professor Julie Irving Clare Bloodworth Dr Nicholas Bown Marian Case Dr Linda Hogarth et al.	Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis	2005
Dr Andrew Hall Professor Julie Irving Lynne Minto	Relation between genetic variants of the ataxia telangiectasia-mutated (ATM) gene, drug resistance, clinical outcome and predisposition to childhood T-lineage acute lymphoblastic leukaemia	2005
Sarina Sulong Marian Case Lynne Minto Dr Bridget Wilkins Dr Andrew Hall et al.	The V617F mutation in Jak2 is not found in childhood acute lymphoblastic leukaemia	2005
Dr Sandeep Pal Lynne Minto Dr Andrew Hall	Antibodies against 9-O-acetylated sialoglycans: A potent marker to monitor clinical status in childhood acute lymphoblastic leukemia	2004
Dr Mark Velangi Elizabeth Matheson Dr Penelope Taylor Professor Graham Jackson Dr Andrew Hall et al.	BRAF gene is not mutated in mismatch repair-proficient or -deficient plasma cell dyscrasias	2004
Dr Mark Velangi Elizabeth Matheson Professor Graham Jackson Dr Penelope Taylor Dr Andrew Hall et al.	DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma	2004
Professor Penny Lovat Professor Andrew Pearson Dr Andrew Hall Dr Chris Redfern	Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide	2004
Dr Andrew Hall Professor Julie Irving Lynne Minto	Genetic variants of ataxia telangiectasia mutated (ATM) and susceptibility for childhood T-lineage acute lymphoblastic leukemia.	2004
Dr Andrew Hall Clare Bloodworth Dr Linda Hogarth Dr Nicholas Bown Professor Julie Irving et al.	Loss of heterozygosity in childhood acute lymphoblastic leukaemia detected by genome-wide microarray single nucleotide polymorphism analysis	2004
Dr Akheel Syed Professor Julie Irving Dr Chris Redfern Dr Andrew Hall Professor Nigel Unwin et al.	Low Prevalence of the N363S Polymorphism of the Glucocorticoid Receptor in South Asians Living in the United Kingdom	2004
Dr Sally Coulthard Dr Andrew Hall Dr Linda Hogarth	The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment	2004
Professor Julie Irving Professor Stephen O'Brien Dr Anne Lennard Lynne Minto Dr Feng Lin et al.	Use of Denaturing HPLC for Detection of Mutations in the BCR-ABL Kinase Domain in Patients Resistant to Imatinib	2004
Elizabeth Matheson Dr Andrew Hall	Assessment of mismatch repair function in leukaemic cell lines and blasts from children with acute lymphoblastic leukaemia	2003
Dr Andrew Hall	ATM (Ataxia Telangiectasia Mutated) gene alterations are frequently found in childhood T-ALL	2003
Dr Mark Velangi Professor Graham Jackson Dr Penelope Taylor Dr Andrew Hall Professor Julie Irving et al.	DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma	2003
Dr Pamela Kearns Professor Zofia Chrzanowska-Lightowlers Dr Andrew Hall	Expression of GSTM isoforms in childhood acute lymphoblastoid leukaemia	2003
Elizabeth Matheson Dr Andrew Hall	Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX	2003
Penelope Mason Elizabeth Matheson Dr Andrew Hall Professor Robert Lightowlers	Mismatch repair activity in mammalian mitochondria	2003
Dr Andrew Hall Elizabeth Matheson	Mismatch repair defects in acute lymphoblastic leukaemia	2003
Dr Andrew Hall Dr Sally Coulthard Professor Julie Irving	Molecular diagnostics: a healthcare perspective	2003
Dr Pamela Kearns Professor Zofia Chrzanowska-Lightowlers Dr Andrew Hall	Mu class glutathione S-transferase mRNA isoform expression in acute lymphoblastic leukaemia	2003
Mark Leslie Marian Case Dr Andrew Hall Dr Sally Coulthard	Potential use of asparagine synthetase levels in the individualisation of L-asparaginase therapy	2003
Clare Bloodworth Dr Linda Hogarth Dr Andrew Hall	Role of mismatch repair in determining sensitivity to the topoisomerase II poisons	2003
Dr Linda Hogarth Dr Sally Coulthard Dr Andrew Hall Lindi Skitt	The effect of thiopurine methyltransferase on the cytotoxic action of thiopurine drugs	2003
Professor Julie Irving Professor Stephen O'Brien Dr Anne Lennard Dr Feng Lin Dr Andrew Hall et al.	The use of denaturing high-performance liquid chromatography (DHPLC) for the detection of mutations in the bcr-abl oncogene in patients resistant to imatinib	2003
Nadia Thornton Dr Andrew Hall Dr Sally Coulthard	The use of real-time PCR to validate methylthioadenosine phosphorylase and p16 deletions as a new drug target in childhood acute lymphoblastic leukaemia	2003
Dr Andrew Hall	Cellular glutathione content, in vitro chemoresponse, and the effect of BSO modulation in samples derived from patients with advanced ovarian cancer	2002
Diana Levett Dr Andrew Hall Dr John Hanley Professor Julie Irving	Comparitive study of conformation sensitive gel electrophoresis (CSGE) and denaturing high pressure liquid chromatography (DHPLC) for mutation detection in von Willebrands disease	2002
Dr John Anderson Dr Katrina Wood Professor John Lunec Dr Andrew Hall Dr Michael Reid et al.	Loss of nuclear expression of the p33ING1b inhibitor of growth protein in childhood acute lymphoblastic leukaemia	2002
Dr Andrew Hall Professor Julie Irving	New drugs, new drug resistance mechanisms	2002
Dr Sally Coulthard Dr Linda Hogarth Dr Margaret Little Elizabeth Matheson Dr Chris Redfern et al.	The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs	2002
Elizabeth Matheson Dr Andrew Hall	Drug discovery - High throughput automated 2-D gel analysis - Tutorial: Proteomic analysis with nonlinear dynamics' progenesis image analysis software	2001
Dr Linda Hogarth Dr Margaret Little Lynne Minto Dr Chris Redfern Dr Andrew Hall et al.	High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine.	2001
Dr Linda Hogarth Dr Margaret Little Lynne Minto Dr Chris Redfern Dr Andrew Hall et al.	In vitro evidence for differences in 6-mercaptopurine versus 6-thioguanine metabolism depending on TPMT status	2001
Mark Leslie Marian Case Dr Andrew Hall Dr Sally Coulthard	Measurement of aspargine synthetase mRNA levels by real-time PCR	2001
Professor Julie Irving Dr Andrew Hall	Mismatch repair defects as a cause of resistance to cytotoxic drugs	2001
Dr John Anderson Professor John Lunec Dr Andrew Hall Dr Michael Reid Dr Brian Angus et al.	p33(ING1b) tumour suppresser protein expression in childhood acute lymphoblastic leukaemia by immunohistochemistry	2001
Professor Ann Daly Dr Andrew Hall	Pharmacogenetics of cytotoxic drugs	2001
Dr Pamela Kearns Professor Andrew Pearson Dr Andrew Hall	Raised blast glutathione levels are associated with an increased risk of relapse in childhood acute lymphocytic leukemia	2001
Dr Sally Coulthard Dr Andrew Hall	Recent advances in the pharmacogenomics of thiopurine methyltransferase	2001
Professor Julie Irving Dr Penelope Taylor Professor Graham Jackson Dr Andrew Hall	The presence of mismatch repair defects in plasma cell dyscrasias	2001
Professor Simon Bailey Dr Andrew Hall Professor Andrew Pearson Dr Chris Redfern	The role of AP-1 in glucocorticoid resistance in leukaemia	2001
Dr Andrew Hall Dr Peter Hamilton Lynne Minto Dr Sally Coulthard	The use of denaturing high-pressure liquid chromatography for the detection of mutations in thiopurine methyltransferase	2001
Dr Sally Coulthard Dr Christopher Howell Lynne Minto Dr Peter Middleton Professor Graham Jackson et al.	A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations	2000
Dr Andrew Hall	Demonstration of functional DNA mismatch repair in lymphoblasts from patients with leukaemia	2000
Marian Case Dr Andrew Hall	Glutathione homeostasis in buthionine sulfoximine sensitive and resistant neuroblastoma cell lines	2000
Dr Sally Coulthard Dr Linda Hogarth Lynne Minto Dr Chris Redfern Dr Andrew Hall et al.	High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine	2000
Dr Linda Hogarth Elizabeth Matheson Lynne Minto Dr Margaret Little Dr Andrew Hall et al.	Measurement of resistance to thiopurine drugs in cells with defective mismatch repair	2000
Dr Andrew Hall	Optimizing antimetabolite-based chemotherapy for the treatment of childhood acute lymphoblastic leukaemia	2000
Dr Andrew Hall	Analysis of thiopurine methyltransferase variant alleles in childhood acute lymphoblastic leukaemia	1999
Dr Pamela Kearns Dr Andrew Hall Professor Andrew Pearson	Different expression of glutathione S-transferase α, µ and π in childhood acute lymphoblastic and myeloid leukaemia	1999
Dr Andrew Hall	Evidence for the involvement of the glutathione pathway in drug resistance in AML	1999
Professor Simon Bailey Dr Andrew Hall Professor Andrew Pearson Dr Michael Reid Dr Chris Redfern et al.	Glucocorticoid resistance and the AP-1 transcription factor in leukaemia	1999
Dr Andrew Hall	Glutathione and the regulation of cell death	1999
Dr Pamela Kearns Professor Andrew Pearson Dr Andrew Hall	Glutathione in childhood acute leukaemias	1999
Dr Linda Hogarth Dr Andrew Hall	Increased BAX expression is associated with an increased risk of relapse in childhood acute lymphocytic leukemia	1999
Andrew Lodge Dr Andrew Hall Dr Katrina Wood Dr John Anderson Dr Brian Angus et al.	NCL-CD10-270: A new monoclonal antibody recognizing CD10 in paraffin- embedded tissue	1999
Dr Andrew Hall	The role of glutathione in the regulation of apoptosis	1999
Andrew Lodge Dr Andrew Hall Dr John Anderson Dr Michael Reid Dr Brian Angus et al.	A study of the prognostic significance of topoisomerase IIα in childhood acute lymphoblastic Leukaemia	1998
Professor Roderick Skinner Dr Andrew Hall Professor Andrew Pearson	Acute changes in urine protein excretion may predict chronic ifosfamide nephrotoxicity: a preliminary observation	1998
Dr Pamela Kearns Dr Andrew Hall	Glutathione and the response of malignant cells to chemotherapy	1998
Dr Pamela Kearns Professor Andrew Pearson Dr Andrew Hall	Glutathione levels in leukaemic blasts	1998
Dr Sally Coulthard Dr Christopher Howell Jill Robson Dr Andrew Hall	The relationship between thiopurine methyltransferase activity and genotype in blasts from patients with acute leukemia	1998
Dr Andrew Hall Professor John Lunec Professor Herbie Newell Professor Andrew Pearson Geoffrey Taylor et al.	Thymidylate synthase expression in nolatrexed and methotrexate-resistant human leukaemia cell lines	1998
Dr Pamela Kearns Dr Andrew Hall	Alkylating agent resistance in pediatric oncology	1997
Professor Alan Calvert Dr Andrew Hall Professor John Lunec Professor Herbie Newell Professor Andrew Pearson et al.	The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ® in human leukaemia and colorectal carcinoma cell lines	1997
Dr Andrew Hall Dr Janet McLelland	Thiopurine methyltransferase levels should be measured before commencing patients on azathioprine	1997
Dr Andrew Hall Professor Graham Jackson	Congenital deficiency of thiopurine methyltransferase as a cause of pancytopenia in patients treated with azathioprine	1996
Dr Andrew Hall Dr Linda Hogarth	Sensitivity of testis tumour cells to chemotherapeutic drugs: Role of detoxifying pathways	1996
Dr Linda Hogarth Professor Andrew Pearson Dr Andrew Hall	The effect of treatment with high dose melphalan, cisplatin or carboplatin on levels of glutathione in plasma, erythrocytes, mononuclear cells and urine	1996
Dr Andrew Hall Professor Alan Calvert Dr James Sunter Professor Herbie Newell	The relationship between tumour glutathione concentration, glutathione S-transferase isoenzyme expression and response to single agent carboplatin in epithelial ovarian cancer patients	1996
Dr Michael Reid Elizabeth Matheson Dr Penelope Taylor Professor Stephen Proctor Dr Andrew Hall et al.	Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia	1995
Dr Andrew Hall	Second primary head and neck squamous cell carcinoma predicted by the glutathione S-transferase expression in healthy tissue in the direct vicinity of the first tumor	1995
Dr Andrew Hall Professor Archibald Malcolm Mike Cole Dr Jennifer Kernahan Dr Michael Reid et al.	Expression of mu class glutathione S-transferase correlates with event-free survival in childhood acute lymphoblastic leukemia	1994
Dr Andrew Hall Professor Andrew Pearson Professor Archibald Malcolm Dr Michael Reid	Glutathione S-transferase in bone marrow metastases of disseminated neuroblastoma	1994
Dr Andrew Hall Professor Hermann Josef Vormoor	Increased DNA-repair capacity and the modulation of 2 proteins in and metallothionein overexpressing Chinese hamster cell line	1994
Dr Andrew Hall Elizabeth Matheson Dr Linda Hogarth	Purification of an alpha class glutathione S-transferase from melphalan-resistant Chinese hamster ovary cells and demonstration of its ability to catalyze melphalan-glutathione adduct formation	1994
Dr Linda Hogarth Dr Michael Reid Professor Stephen Proctor Dr Peter Hamilton Dr Andrew Hall et al.	Raised intracellular glutathione levels correlate with in vitro resistance to cytotoxic drugs in leukaemic cells from patients with acute lymphoblastic leukaemia	1994
Dr Michael Reid Professor Andrew Pearson Professor Stephen Proctor Dr Peter Hamilton Dr Andrew Hall et al.	The relationship between bcl-2 expression and response to chemotherapy in acute leukaemia	1994
Dr Linda Hogarth Dr Andrew Hall	Cytosolic glutathione (GSH) levels of leukemic blasts in relation to in vitro anthracycline resistance	1993
Dr Andrew Hall Professor Robert Lightowlers	Identification of bovine glutamate dehydrogenase as an RNA-binding protein	1993
Dr Andrew Hall Dr Michael Reid Professor Stephen Proctor	Invitro drug sensitivity testing in acute lymphoblastic-leukemia using the tetrazolium-based MTT assay	1993
Dr Andrew Hall Deanne Crowther	Glutathione S-transferase activity and isoenzyme distribution in ovarian tumour biopsies taken before or after cytotoxic chemotherapy	1992
Dr Andrew Hall Dr Robert Nelson Professor Alastair Burt	Glutathione S-transferases in neonatal liver disease	1992
Craig Wright Dr Andrew Hall	Immunohistochemical demonstration of glutathione S-transferases in primary human breast carcinomas	1992
Dr Andrew Hall Dr Michael Tilby	Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies	1992
Professor Craig Robson Dr Andrew Hall	Reduced topoisomerase II and elevated α class glutathione S-transferase expression in a multidrug resistant CHO cell line highly cross-resistant to mitomycin C	1992
Dr Christopher Wright Dr Andrew Hall	Response to mitoxantrone in advanced breast cancer: correlation with expression of c-erbB-2 protein and glutathione S-transferases	1992
Dr Sally Davies Dr Andrew Hall	Isolation and partial characterisation of a mammalian cell mutant hypersensitive to topoisomerase II inhibitors and X-rays	1990
Dr Brian Angus Dr Andrew Hall Professor Stephen Proctor	Glutathione S-transferase (placental) as a marker of transformation in the human cervix uteri: an immunohistochemical study	1990
Dr Andrew Hall Professor Stephen Proctor	Purification and characterization of a pi class glutathione S-transferase from human leukaemic cells	1990
Dr Andrew Hall Dr Charles Kelly	Exercise testing soon after myocardial infarction: its relation to course and outcome at one year in patients aged less than 55 years	1989
Dr Andrew Hall Professor Stephen Proctor	Mechanisms of drug resistance in acute leukaemia	1989
Dr Andrew Hall Professor Craig Robson Professor Stephen Proctor	Possible role of inhibition of glutathione S-transferase in the partial reversal of chlorambucil resistance by indomethacin in a Chinese hamster ovary cell line	1989
Dr Andrew Hall Professor Craig Robson Professor Stephen Proctor	Potentation of alkylating agents using indomethacin	1988
Professor Craig Robson Dr Andrew Hall	Bleomycin and X-ray-hypersensitive Chinese hamster ovary cell mutants: Genetic analysis and cross-resistance to neocarzinostatin	1988
Dr Andrew Hall Professor Stephen Proctor	Case report: Hodgkin's disease involving the large bowel	1988
Dr Andrew Hall Professor Stephen Proctor Dr Peter Saunders	Increased platelet associated immunoglobulin in myelodysplastic syndromes	1987
Dr Andrew Hall Professor Anne Dickinson Professor Stephen Proctor	Measurement of in vitro drug sensitivity to human myeloma and chronic lymphocytic-leukemia	1987
Professor Craig Robson Dr Andrew Hall Professor Stephen Proctor	Reduced levels of drug-induced DNA cross-linking in nitrogen mustard-resistant Chinese hamster ovary cells expressing elevated glutathione S-transferase activity	1987
Dr Andrew Hall Professor Stephen Proctor	Melphalan resistance in myeloma	1986
Professor Stephen Proctor Dr Peter Hamilton Dr Michael Reid Dr Andrew Hall	Progress in acute leukaemia in adults	1986