Publications by Dr Sally Coulthard - ePrints

Browsing publications by Dr Sally Coulthard.

Newcastle Authors	Title	Year
Dr Chris Redfern Dr Sally Coulthard	Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation	2021
Dr Tom Chamberlain Dr Sally Coulthard Mohammad Alshabeeb Professor Ann Daly	Drug‐Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles	2019
Dr Sally Coulthard Dr Chris Redfern	Metabolites of endophytic fungi from Australian native plants as potential anticancer agents	2018
Dr Sally Coulthard Sarah McGarrity Dr Kiran Sahota Philip Berry Dr Chris Redfern et al.	Three Faces of Mercaptopurine Cytotoxicity in vitro: Methylation, Nucleotide Homeostasis and Deoxythioguanosine in DNA	2018
Dr Sally Coulthard Professor Chris Day Professor Ann Daly	Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study	2017
Dr Sally Coulthard Philip Berry Sarah McGarrity Dr Chris Redfern	Azathioprine with Allopurinol: Lower Deoxythioguanosine in DNA and Transcriptome Changes Indicate Mechanistic Differences to Azathioprine Alone	2017
Dr Sally Coulthard Philip Berry Sarah McGarrity Dr Chris Redfern	A Novel Assay for The Direct Detection of Deoxythioguanosine (DTG) in DNA from Patients On Azathioprine Using Liquid Chromatography and Tandem Mass Spectrometry (LC-MS/MS)	2016
Dr Sally Coulthard Philip Berry Sarah McGarrity Abdul-Haq Ansari Dr Chris Redfern et al.	Deoxythioguanosine (DTG) in DNA as a Pharmacological Endpoint of Thiopurine Treatment in Inflammatory Bowel Disease Patients	2016
Dr Sally Coulthard Professor Ann Daly	HLA-DRB116:01-DQB105:02 is a novel genetic risk factor for flupirtine-induced liver injury	2016
Dr Sally Coulthard Philip Berry Sarah McGarrity Dr Chris Redfern	Liquid chromatography-mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients	2016
Dr Sally Coulthard Philip Berry Sarah McGarrity Dr Chris Redfern	Liquid chromatography-mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients	2016
Dr Sally Coulthard Professor Ann Daly	Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting	2016
Dr Sally Coulthard Philip Berry Sarah McGarrity Dr Chris Redfern	Direct Detection of Thiopurine Metabolites in Erythrocytes and Leukocytes Using a Novel LCMS/MS Method to Interrogate Drug Response and in vivo Metabolism	2014
Dr Sally Coulthard	Nomenclature for alleles of the thiopurine methyltransferase gene	2013
Professor Ann Daly Professor Gareth Veal Dr David Jamieson Dr Sally Coulthard	Pharmacogenomics research at Newcastle University	2012
Dr Sally Coulthard Dr Chris Redfern Svante Vikingsson Dr Malin Lindqvist Appell Dr Andrew Hall et al.	Increased Sensitivity to Thiopurines in Methylthioadenosine Phosphorylase-Deleted Cancers	2011
Tomasz Zaremba Huw Thomas Mike Cole Dr Sally Coulthard Professor Ruth Plummer et al.	Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers	2011
Dr Sally Coulthard Dr Chris Redfern Dr Linda Hogarth	Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers [abstract]	2010
Dr Sally Coulthard	Thiopurines: Factors influencing toxicity and response	2010
Professor Ruth Plummer Melanie Griffin Dr Sally Coulthard Julieann Sludden Professor Alan Calvert et al.	Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors	2009
Tomasz Zaremba Professor Ruth Plummer Dr Sally Coulthard Mike Cole Professor Nicola Curtin et al.	Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in a panel of human tumor cell lines [abstract]	2009
Tomasz Zaremba Mike Cole Dr Sally Coulthard Professor Ruth Plummer Professor Nicola Curtin et al.	Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines	2009
Dr Sally Coulthard	Thiopurine methyltransferase genetics is not a major risk factor for secondary malignant neoplasms after treatment of childhood acute lymphoblastic leukemia on Berlin-Frankfurt-Munster protocols	2009
Tomasz Zaremba Mike Cole Dr Sally Coulthard Professor Ruth Plummer Professor Nicola Curtin et al.	Poly(ADP-ribose) polymerase-1 (PARP-1) genomics in relation to activity in healthy volunteers and cancer patients	2008
Dr Linda Hogarth Dr Chris Redfern Dr Andrew Hall Dr Holly Anderson Marian Case et al.	The effect of thiopurine drugs on DNA methylation in relation to TPMT expression	2008
Mark Leslie Marian Case Dr Andrew Hall Dr Sally Coulthard	Expression levels of asparagine synthetase in blasts from children and adults with acute lymphoblastic leukaemia	2006
Dr Sally Coulthard Dr Linda Hogarth	The thiopurines: An update	2005
Dr Sally Coulthard Dr Linda Hogarth	Old drugs-current perspectives	2004
Dr Sally Coulthard Dr Andrew Hall Dr Linda Hogarth	The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment	2004
Professor Gareth Veal Dr Sally Coulthard Professor Alan Boddy	Chemotherapy individualization	2003
Dr Andrew Hall Dr Sally Coulthard Professor Julie Irving	Molecular diagnostics: a healthcare perspective	2003
Mark Leslie Marian Case Dr Andrew Hall Dr Sally Coulthard	Potential use of asparagine synthetase levels in the individualisation of L-asparaginase therapy	2003
Dr Linda Hogarth Dr Sally Coulthard Dr Andrew Hall Lindi Skitt	The effect of thiopurine methyltransferase on the cytotoxic action of thiopurine drugs	2003
Nadia Thornton Dr Andrew Hall Dr Sally Coulthard	The use of real-time PCR to validate methylthioadenosine phosphorylase and p16 deletions as a new drug target in childhood acute lymphoblastic leukaemia	2003
Dr Sally Coulthard Dr Linda Hogarth Dr Margaret Little Elizabeth Matheson Dr Chris Redfern et al.	The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs	2002
Dr Linda Hogarth Dr Margaret Little Lynne Minto Dr Chris Redfern Dr Andrew Hall et al.	High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine.	2001
Dr Linda Hogarth Dr Margaret Little Lynne Minto Dr Chris Redfern Dr Andrew Hall et al.	In vitro evidence for differences in 6-mercaptopurine versus 6-thioguanine metabolism depending on TPMT status	2001
Mark Leslie Marian Case Dr Andrew Hall Dr Sally Coulthard	Measurement of aspargine synthetase mRNA levels by real-time PCR	2001
Dr Sally Coulthard Dr Andrew Hall	Recent advances in the pharmacogenomics of thiopurine methyltransferase	2001
Dr Andrew Hall Dr Peter Hamilton Lynne Minto Dr Sally Coulthard	The use of denaturing high-pressure liquid chromatography for the detection of mutations in thiopurine methyltransferase	2001
Dr Sally Coulthard Dr Christopher Howell Lynne Minto Dr Peter Middleton Professor Graham Jackson et al.	A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations	2000
Dr Sally Coulthard Dr Linda Hogarth Lynne Minto Dr Chris Redfern Dr Andrew Hall et al.	High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine	2000
Dr Sally Coulthard Dr Christopher Howell Jill Robson Dr Andrew Hall	The relationship between thiopurine methyltransferase activity and genotype in blasts from patients with acute leukemia	1998
Dr Sally Coulthard Dr Anne Lennard	Abnormalities of chromosome band 8p11 in leukemia: Two clinical syndromes can be distinguished on the basis of MOZ involvement	1997
Dr David Wilson Ian Cross Professor Judith Goodship Dr Sally Coulthard Dr Hugh Bain et al.	DiGeorge syndrome with isolated aortic coarctation and isolated ventricular septal defect in three sibs with a 22q11 deletion of maternal origin	1991