Publications by Dr Nichola Lax - ePrints

Browsing publications by Dr Nichola Lax.

Newcastle Authors	Title	Year
Dr Laura Alexandra Smith Dr Chun Chen Dr Nichola Lax Professor Robert Taylor Dr Daniel Erskine et al.	Astrocytic pathology in Alpers’ syndrome	2023
Chris Hatton Dr Amy Reeve Dr Nichola Lax Dr Alasdair Blain Dr Yi Ng et al.	Complex I reductions in the nucleus basalis of Meynert in Lewy body dementia: the role of Lewy bodies	2020
Dr Daniel Erskine Dr Amy Reeve Dr Tuomo Polvikoski Dr Andrew Schaefer Professor Robert Taylor et al.	Lewy body pathology is more prevalent in older individuals with mitochondrial disease than controls	2020
Dr Hannah Hayhurst Maria Anagnostou Helen Bogle Dr John Grady Professor Robert Taylor et al.	Dissecting the neuronal vulnerability underpinning Alpers' syndrome: A clinical and neuropathological study	2019
Dr Nichola Lax Shuna Whyte Dr Alistair Jenkins Emeritus Professor Doug Turnbull Mark Cunningham et al.	The role of astrocytes in seizure generation: insights from a novel in vitro seizure model based on mitochondrial dysfunction	2019
Dr Yi Ng Dr Nichola Lax Dr Charlotte Alston Philippa Hepplewhite Professor Patrick Chinnery et al.	MT-ND5 Mutation Exhibits Highly Variable Neurological Manifestations at Low Mutant Load	2018
Dr Kyle Thompson Dr Monika Olahova Dr Filippo Scialo Dr Nichola Lax Dr Fiona Robertson et al.	OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect	2018
Dr Nichola Lax Professor Grainne Gorman Emeritus Professor Doug Turnbull	Central nervous system involvement in mitochondrial disease	2017
Dr Charlotte Alston Dr Mariana Rocha Dr Nichola Lax Emeritus Professor Doug Turnbull Professor Robert Taylor et al.	The genetics and pathology of mitochondrial disease	2017
Dr Ahmad Khundakar Dr Peter Hanson Dr Daniel Erskine Dr Nichola Lax Evangelia Karyka et al.	Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations	2016
Jonathan Phillips Dr Alex Laude Professor Robert Lightowlers Dr Christopher Morris Emeritus Professor Doug Turnbull et al.	Development of passive CLARITY and immunofluorescent labelling of multiple proteins in human cerebellum: understanding mechanisms of neurodegeneration in mitochondrial disease	2016
Dr Nichola Lax Dr John Grady Dr Alex Laude Felix Chan Philippa Hepplewhite et al.	Extensive respiratory chain defects in inhibitory interneurones in patients with mitochondrial disease	2016
Alexia Chrysostomou Dr John Grady Dr Alex Laude Professor Robert Taylor Emeritus Professor Doug Turnbull et al.	Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease	2016
Jonathan Phillips Dr Hannah Hayhurst Dr Nichola Lax	Neurodegeneration in mitochondrial disorders	2016
Felix Chan Dr Nichola Lax Emeritus Professor Doug Turnbull Professor Mark Cunningham	Neuronal oscillations: a physiological correlate for targeting mitochondrial dysfunction in neurodegenerative diseases?	2016
Dr Yi Ng Dr John Grady Dr Nichola Lax Dr John Bourke Dr Charlotte Alston et al.	Sudden adult death syndrome in m.3243A>G-related mitochondrial disease: an unrecognized clinical entity in young, asymptomatic adults	2016
Professor Roger Whittaker Professor Grainne Gorman Dr Andrew Schaefer Professor Rita Horvath Dr Yi Ng et al.	Epilepsy in Adults With Mitochondrial Disease: A Cohort Study	2015
Dr Nichola Lax Dr Langping He Gavin Falkous Professor Bobby McFarland Professor Robert Taylor et al.	Neuropathologic Characterization of Pontocerebellar Hypoplasia Type 6 Associated With Cardiomyopathy and Hydrops Fetalis and Severe Multisystem Respiratory Chain Deficiency due to Novel RARS2 Mutations	2015
Dr Anne Grunewald Dr Nichola Lax Dr Amy Reeve Philippa Hepplewhite Karolina Rygiel et al.	Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue	2014
Dr Yi Ng Dr Nichola Lax Dr Andrew Schaefer Professor Robert Taylor Emeritus Professor Doug Turnbull et al.	Sudden Unexpected Death in Adults with M.3243A>G Mutation	2014
Dr Nichola Lax Dr Charlotte Alston Dr Tuomo Polvikoski Dr Evelyn Jaros Dr John Yarham et al.	Early-Onset Cataracts, Spastic Paraparesis, and Ataxia Caused by a Novel Mitochondrial tRNA(Glu) (MT-TE) Gene Mutation Causing Severe Complex I Deficiency: A Clinical, Molecular, and Neuropathologic Study	2013
Helen Bogle Dr Nichola Lax Dr Evelyn Jaros Professor Bobby McFarland Professor Robert Taylor et al.	Neuropathological changes in Alpers' syndrome	2013
Dr Amy Reeve Dr Martin Meagher Dr Nichola Lax Dr Eve Cosgrave Philippa Hepplewhite et al.	The Impact of Pathogenic Mitochondrial DNA Mutations on Substantia Nigra Neurons	2013
Dr Nichola Lax Philippa Hepplewhite Dr Amy Reeve Dr Victoria Nesbitt Professor Bobby McFarland et al.	Cerebellar Ataxia in Patients With Mitochondrial DNA Disease: A Molecular Clinicopathological Study	2012
Dr Nichola Lax Graham Campbell Dr Amy Reeve Jessica Zambonin Professor Robert Taylor et al.	Loss of Myelin-Associated Glycoprotein in Kearns-Sayre Syndrome	2012
Dr Nichola Lax Dr Ilse Pienaar Dr Amy Reeve Philippa Hepplewhite Dr Evelyn Jaros et al.	Microangiopathy in the cerebellum of patients with mitochondrial DNA disease	2012
Dr Nichola Lax Emeritus Professor Doug Turnbull	Mitochondrial allostatic load? The combined effect of glucose intolerance and mitochondrial DNA mutations on the incidence of neurological symptoms	2012
Dr Nichola Lax Dr Evelyn Jaros	Neurodegeneration in primary mitochondrial disorders	2012
Dr Amy Reeve Tae-Kyung Park Dr Evelyn Jaros Graham Campbell Dr Nichola Lax et al.	Relationship Between Mitochondria and α-Synuclein: A Study of Single Substantia Nigra Neurons	2012
Dr Nichola Lax Professor Roger Whittaker Philippa Hepplewhite Dr Amy Reeve Dr Evelyn Jaros et al.	Sensory neuronopathy in patients harbouring recessive polymerase γ mutations	2012
Dr Nichola Lax Emeritus Professor Doug Turnbull Dr Amy Reeve	Mitochondrial mutations: newly discovered players in neuronal degeneration	2011
Dr Nichola Lax Dr Daria Diodato Emeritus Professor Doug Turnbull	The mitochondrial brain: From mitochondrial genome to neurodegeneration	2010
Dr Don Mahad Dr Iryna Ziabreva Graham Campbell Dr Nichola Lax Dr Kathryn White et al.	Mitochondrial changes within axons in multiple sclerosis	2009