Publications by Dr Birthe Hilgen - ePrints

Browsing publications by Dr Birthe Hilgen.

Newcastle Authors	Title	Year
Dr Maria Georgiou Alex Chaudhary Dr Joseph Collin Dr Rachel Queen Dr Birthe Hilgen et al.	Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina	2022
Dr Marzena Kurzawa-Akanbi Dr Florence Burte Dr Birthe Hilgen Dr Rachel Queen Dr Jonathan Coxhead et al.	Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina	2022
Dr Darin Zerti Marina Moya-Molina Dr Birthe Hilgen Dr Roman Bauer Professor Majlinda Lako et al.	IGFBPs mediate IGF-1’s functions in retinal lamination and photoreceptor development during pluripotent stem cell differentiation to retinal organoids	2021
Dr Darin Zerti Dr Birthe Hilgen Dr Joseph Collin Professor Lyle Armstrong Professor Evelyne Sernagor et al.	Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration	2021
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Maria Georgiou et al.	Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface	2020
Dr Darin Zerti Dr Birthe Hilgen Majed Felemban Dr Ali Ghareeb Dr Min Yu et al.	Developing a simple method to enhance the generation of cone and rod photoreceptors in pluripotent stem cell‐derived retinal organoids	2020
Dr Maria Georgiou Dr Valeria Chichagova Dr Birthe Hilgen Professor Evelyne Sernagor Professor Lyle Armstrong et al.	Room temperature shipment does not affect the biological activity of pluripotent stem cell-derived retinal organoids	2020
Dr Carla Jackson Dr Roman Bauer Dr Joseph Collin Dr Birthe Hilgen Dr Darin Zerti et al.	An integrated transcriptional analysis of the developing human retina	2019
Majed Felemban Dr Birthe Hilgen Dr Darin Zerti Dr Nicola Hunt Dr Dean Hallam et al.	Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids	2019
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Raf Hussain et al.	Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina	2019
Dr Valeria Chichagova Dr Birthe Hilgen Majed Felemban Dr Maria Georgiou Professor Lyle Armstrong et al.	Differentiation of Retinal Organoids from Human Pluripotent Stem Cells	2019
Dr Carla Jackson Dr Joseph Collin Dr Rachel Queen Dr Birthe Hilgen Dr Darin Zerti et al.	Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences	2019
Dr Valeria Chichagova Dr Dean Hallam Dr Joseph Collin Dr Darin Zerti Dr Birthe Hilgen et al.	Cellular regeneration strategies for macular degeneration: past, present and future	2018
Majed Felemban Dr Birthe Hilgen Dr Nicola Hunt Dr Dean Hallam Dr Darin Zerti et al.	Extracellular matrix components expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix	2018
Dr Dean Hallam Dr Birthe Hilgen Dr Lili Zhu Dr Min Yu Dr Sanja Bojic et al.	Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency	2018
Dr Birthe Hilgen Majed Felemban Alex Sharpe Dr Roman Bauer Dr Dean Hallam et al.	Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation	2018
Dr Joseph Collin Dr Carla Jackson Dr Birthe Hilgen Professor Majlinda Lako	Using Zinc Finger Nuclease Technology to Generate CRX-Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation	2016
Dr Birthe Hilgen	Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions	2015
Majed Felemban Dr Nicola Hunt Dr Birthe Hilgen Dr Carla Mellough Professor Majlinda Lako et al.	Investigation of extracellular matrix (ECM) component expression in developing retina	2015
Professor Majlinda Lako Dr Joseph Collin Dr Carla Jackson Dr Birthe Hilgen	Using zinc finger nuclease technology to generate reporter-labelled human pluripotent stem cells as a tool to optimize photoreceptor transplantation	2015
Dr Gerrit Hilgen Dr Birthe Hilgen	AII amacrine cells discriminate between heterocellular and homocellular locations when assembling connexin36-containing gap junctions	2014
Dr Katarina Kranz Dr Birthe Hilgen	Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout	2013
Dr Birthe Hilgen	Ablation of Retinal Horizontal Cells from Adult Mice Leads to Rod Degeneration and Remodeling in the Outer Retina	2012