Publications by Emeritus Professor Andrew Mellor - ePrints

Browsing publications by Emeritus Professor Andrew Mellor.

Newcastle Authors	Title	Year
Dr Rui Chen Dr Jarmila Spegarova Dr Joe Willet Dr Helen Griffin Dr Akshada Gajbhiye et al.	NUDCD3 deficiency disrupts V(D)J recombination to cause SCID and Omenn syndrome	2024
Gemma Vidal Pedrola Najib Naamane Dr Arthur Pratt Emeritus Professor Andrew Mellor Professor John Isaacs et al.	Characterization of age-associated B cells in early drug-naïve rheumatoid arthritis patients	2023
Dr Lei Huang Emeritus Professor Andrew Mellor	Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment	2021
Nga Vo Dr Lei Huang Emeritus Professor Andrew Mellor Professor Katarina Novakovic	Genipin‐crosslinked chitosan hydrogels: Preliminary evaluation of the in vitro biocompatibility and biodegradation	2021
Dr Lei Huang Emeritus Professor Andrew Mellor	Indoleamine 2,3 Dioxygenase, Age, and Immune Activation in People Living with Hiv	2021
Dr Emily Thompson Lucy Bates Dr Ibrahim Ibrahim Dr Avinash Sewpaul Rodrigo Figueiredo et al.	Novel delivery of cellular therapy to reduce ischaemia reperfusion injury in kidney transplantation	2021
Dr Nicola Maney Dr Ben Barron-Millar Dr Christopher Carey Ian Herron Dr Amy Anderson et al.	Pim Kinases as Therapeutic Targets in Early Rheumatoid Arthritis	2021
Dr Lei Huang Emeritus Professor Andrew Mellor	STING Negatively Regulates Allogeneic T-Cell Responses by Constraining Antigen-Presenting Cell Function	2021
Dr Daniel Lin Dr Lei Huang James O'Hara Emerita Professor Janet Wilson Emeritus Professor Andrew Mellor et al.	The immunotherapeutic role of indoleamine 2,3-dioxygenase in head and neck squamous cell carcinoma: A systematic review	2021
Dr Lei Huang Emeritus Professor Andrew Mellor	A Validation Study on IDO Immune Biomarkers for Survival Prediction in Non–Small Cell Lung Cancer: Radiation Dose Fractionation Effect in Early-Stage Disease	2020
Dr Lei Huang Emeritus Professor Andrew Mellor	CD40 Accelerates the Antigen-Specific Stem-Like Memory CD8+ T Cells Formation and Human Papilloma Virus (HPV)-Positive Tumor Eradication	2020
Dr Lei Huang Emeritus Professor Andrew Mellor	CD73 on cancer-associated fibroblasts enhanced by the A_2B-mediated feedforward circuit enforces an immune checkpoint	2020
Dr Henrique De Paula Lemos Dr Rong Ou Dr Caroline McCardle Dr Lei Huang Emeritus Professor Andrew Mellor et al.	Co-treatments to boost IDO activity and inhibit production of downstream catabolites induce durable suppression of Experimental Autoimmune Encephalomyelitis	2020
Dr Rong Ou Dr Caroline McCardle Jack Minett Dr Lei Huang Emeritus Professor Andrew Mellor et al.	Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity	2020
Nga Vo Dr Lei Huang Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor Professor Katarina Novakovic et al.	Poly(ethylene glycol)‐interpenetrated genipin‐crosslinked chitosan hydrogels: Structure, pH responsiveness, gelation kinetics, and rheology	2020
Dr Lei Huang Emeritus Professor Andrew Mellor	Adoptive CD8⁺ T cell therapy against cancer：Challenges and opportunities	2019
Dr Henrique De Paula Lemos Dr Lei Huang Emeritus Professor Andrew Mellor	Immune control by amino acid catabolism during tumorigenesis and therapy	2019
Dr Lei Huang Emeritus Professor Andrew Mellor	Limited effect of indolamine 2,3-dioxygenase expression and enzymatic activity on lupus-like disease in b6.Nba2 mice	2019
Emeritus Professor Andrew Mellor Dr Lei Huang	Metabolic requirements for expanding and arming a clone army	2019
Nga Vo Dr Lei Huang Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor Professor Katarina Novakovic et al.	Smart chitosan-based hydrogels for targeted drug delivery applications	2019
Dr Henrique De Paula Lemos Dr Lei Huang Dr Rong Ou Emeritus Professor Andrew Mellor	Stimulator of Interferon Genes Agonists attenuate type I diabetes progression in NOD mice	2019
Dr Lei Huang Emeritus Professor Andrew Mellor	IDO Immune Status after Chemoradiation May Predict Survival in Lung Cancer Patients	2018
Nga Vo Dr Lei Huang Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor Professor Katarina Novakovic et al.	Smart chitosan-based hydrogels for targeted drug delivery application	2018
Dr Henrique De Paula Lemos Dr Lei Huang Emeritus Professor Andrew Mellor	Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity	2017
Emeritus Professor Andrew Mellor Dr Henrique De Paula Lemos Dr Lei Huang	Indoleamine 2,3-Dioxygenase and tolerance: Where Are We Now?	2017
Emeritus Professor Andrew Mellor Dr Henrique De Paula Lemos Dr Lei Huang	Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?	2017
Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor	Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes	2017
Dr Lei Huang Emeritus Professor Andrew Mellor	An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis	2016
Emeritus Professor Andrew Mellor	IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance	2016
Dr Henrique De Paula Lemos Dr Lei Huang Dr Rong Ou Emeritus Professor Andrew Mellor	STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation	2016
Dr Lei Huang Dr Rong Ou Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor	Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase	2016
Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor	Alkylating Agent Melphalan Augments the Efficacy of Adoptive Immunotherapy Using Tumor-Specific CD4⁺ T Cells	2015
Emeritus Professor Andrew Mellor	Canonical Wnt Signaling in Dendritic Cells Regulates Th1/Th17 Responses and Suppresses Autoimmune Neuroinflammation	2015
Emeritus Professor Andrew Mellor	IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.	2015
Dr Henrique De Paula Lemos Dr Lei Huang Emeritus Professor Andrew Mellor	STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy?	2015
Dr Lei Huang Emeritus Professor Andrew Mellor	The PTEN pathway in Tregs is a critical driver for the suppressive tumor microenvironment	2015
Emeritus Professor Andrew Mellor	β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells	2015
Dr Henrique De Paula Lemos Dr Lei Huang Emeritus Professor Andrew Mellor	Activation of the STING Adaptor Attenuates Experimental Autoimmune Encephalitis.	2014
Dr Henrique De Paula Lemos Dr Lei Huang Emeritus Professor Andrew Mellor	Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA	2014
Emeritus Professor Andrew Mellor	GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology	2014
Emeritus Professor Andrew Mellor	IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation	2014
Dr Henrique De Paula Lemos Dr Lei Huang Emeritus Professor Andrew Mellor	Immunosuppressive Myeloid Cells Induced by Chemotherapy Attenuate Antitumor CD4⁺T-Cell Responses through the PD-1-PD-L1 Axis	2014
Emeritus Professor Andrew Mellor	Indoleamine 2,3-dioxygenase (IDO) activity during the primary immune response to influenza infection modifies the memory T cell response to influenza challenge	2014
Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor	Marginal zone CD169⁺ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance	2014
Dr Lei Huang Emeritus Professor Andrew Mellor	Metabolic control of tumour progression and antitumour immunity.	2014
Emeritus Professor Andrew Mellor	T cell costimulation molecules CD80/86 inhibit osteoclast differentiation by inducing the IDO/tryptophan pathway	2014
Emeritus Professor Andrew Mellor	The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma	2014
Emeritus Professor Andrew Mellor	TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation	2014
Dr Henrique De Paula Lemos Fan Pan Emeritus Professor Andrew Mellor	An Inherently Bifunctional Subset of Foxp3⁺ T Helper Cells is Controlled by the Transcription Factor Eos	2013
Emeritus Professor Andrew Mellor	B7h (ICOS-L) maintains tolerance at the fetomaternal interface	2013
Dr Lei Huang Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor	Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses	2013
Emeritus Professor Andrew Mellor	Indoleamine 2,3-Dioxygenase 1 (Ido1) Is Involved in the Control of Mouse Caput Epididymis Immune Environment	2013
Dr Lei Huang Emeritus Professor Andrew Mellor	Induction and role of indoleamine 2,3 dioxygenase in mouse models of influenza a virus infection	2013
Dr Lei Huang Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor	Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases	2012
Dr Lei Huang Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor	Amino acid catabolism: a pivotal regulator of innate and adaptive immunity	2012
Dr Lei Huang Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor	Engineering DNA Nanoparticles as Immunomodulatory Reagents that Activate Regulatory T Cells	2012
Dr Henrique De Paula Lemos Emeritus Professor Andrew Mellor	Leishmania major Attenuates Host Immunity by Stimulating Local Indoleamine 2,3-Dioxygenase Expression	2011
Emeritus Professor Andrew Mellor	B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase	2010
Emeritus Professor Andrew Mellor	Reprogrammed Foxp3⁺ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8⁺ T Cell Priming in Naive Mice	2010
Emeritus Professor Andrew Mellor	IDO activates regulatory T cells and blocks their conversion into Th17-like T cells	2009
Emeritus Professor Andrew Mellor	Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase	2008