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Browsing publications by Dr Edwin Wong.

Newcastle AuthorsTitleYearFull text
Dr Sally Johnson
Professor David Kavanagh
Professor John Sayer
Dr Edwin Wong
Megan Bates
et al.
Description and Cross-Sectional Analyses of 25,880 Adults and Children in the UK National Registry of Rare Kidney Diseases Cohort2024
Dr Sally Johnson
Dr Edwin Wong
Developing Therapies for C3 Glomerulopathy: Report of the Kidney Health Initiative C3 Glomerulopathy Trial Endpoints Work Group2024
Dr Sally Johnson
Professor David Kavanagh
Professor John Sayer
Dr Edwin Wong
Dr Vicky Brocklebank
et al.
Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort2024
Dr Edwin Wong
Lee-Ann Naidoo
Sarah Winn
Dr Patrick Walsh
Dr Vicky Brocklebank
et al.
The Annual Report of the National Renal Complement Therapeutics Centre 2022/232024
Emily Glover
Dr Kate Smith-Jackson
Dr Vicky Brocklebank
Dr Valerie Wilson
Dr Patrick Walsh
et al.
Assessing the Impact of Prophylactic Eculizumab on Renal Graft Survival in Atypical Hemolytic Uremic Syndrome2023
Dr Vicky Brocklebank
Dr Patrick Walsh
Dr Kate Smith-Jackson
Dr Thomas Hallam
Professor Kevin Marchbank
et al.
Atypical haemolytic uraemic syndrome in the era of terminal complement inhibition- An observational cohort study2023
Dr Edwin Wong
Professor David Kavanagh
Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy2023
Dr Ruyue Sun
Dr Long Xie
Rebecca Russell
Dr Edwin Wong
Professor Neil Sheerin
et al.
Pre-eclampsia is associated with complement pathway activation in the maternal and fetal circulation, and placental tissue2023
Dr Edwin Wong
Sarah Winn
Dr Michal Malina
Dr Sally Johnson
Professor Neil Sheerin
et al.
The Annual Report of the National Renal Complement Therapeutics Centre 2021/222023
Dr Thomas Hallam
Tom Cox
Dr Kate Smith-Jackson
Dr Vicky Brocklebank
April Baral
et al.
A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in Age-related Macular Degeneration2022
Emily Hunter
Professor Anthony De Soyza
Dr Rachel Agbeko
Dr Ken Baker
Dr Quentin Campbell Hewson
et al.
Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial2022
Dr Alison Brown
Dr Katrina Wood
Dr Edwin Wong
Paraneoplastic cast nephropathy associated with malignant prolactinoma: A case report and literature review2022
Sarah Dunn
Abishek Umashankar
Andrew Bryant
Dr Sonya Carnell
Dr Thomas Chadwick
et al.
Saftey and impact of eculizumab withdrawal in patients with atypical haemolytic uraemic syndrome: protocol for a multicentre, open-label, prospective, single-arm study2022
Dr Edwin Wong
Thomas Hallam
Dr Vicky Brocklebank
Dr Patrick Walsh
Dr Kate Smith-Jackson
et al.
Functional characterisation of rare genetic variants in the N-terminus of complement factor H in aHUS, C3G and AMD2021
Dr Edwin Wong
Sarah Winn
Dr Michal Malina
Dr Sally Johnson
Professor Neil Sheerin
et al.
The Annual Report of the National Renal Complement Therapeutics Centre 2020/212021
Dr Edwin Wong
Professor Claire Harris
Professor Kevin Marchbank
Dr Sally Johnson
Large scale whole-genome sequencing reveals the genetic architecture of primary membranoproliferative glomerulonephritis and C3 glomerulopathy2020
Dr Vicky Brocklebank
Dr Kate Smith-Jackson
Dr Patrick Walsh
Professor Kevin Marchbank
Professor Claire Harris
et al.
Long-term outcomes and response to treatment in DGKE nephropathy2020
Dr Edwin Wong
Lisa Batchelor
Dr Michal Malina
Dr Sally Johnson
Professor Neil Sheerin
et al.
The Annual Report of the National Renal Complement Therapeutics Centre 2019/202020
Dr Edwin Wong
Jo Stout
Jalibani Ndebele
Angela Watt
Lisa Batchelor
et al.
The Annual Report of the National Renal Complement Therapeutics Centre 2018/192019
Dr Edwin Wong
Professor David Kavanagh
Diseases of complement dysregulation—an overview2018
Professor Patrick Chinnery
Ingrid Emmerson
Professor Rita Horvath
Dr Sally Johnson
Deborah Shipley
et al.
Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data2018
Dr Edwin Wong
Jo Stout
Jalibani Ndebele
Angela Watt
Dr Michal Malina
et al.
The Annual Report of the National Renal Complement Therapeutics Centre 2017/182018
Dr Edwin Wong
Dr Yi Yang
Professor Kevin Marchbank
Professor David Kavanagh
Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self surface-selective regulation of complement activation2017
Dr Vicky Brocklebank
Dr Sally Johnson
Dr Patrick Walsh
Dr Edwin Wong
Dr Larissa Kerecuk
et al.
Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland2017
Professor David Kavanagh
Dr Edwin Wong
Dr Vicky Brocklebank
Hemolytic Uremic Syndrome in Pregnancy and Post-Partum2017
Dr Edwin Wong
Dr Sally Johnson
Professor Neil Sheerin
Professor David Kavanagh
The Annual Report of the National Renal Complement Therapeutics Centre 2016/20172017
Rachel Challis
Dr Edwin Wong
Dr Vicky Brocklebank
Dr Valerie Wilson
Professor Kevin Marchbank
et al.
Thrombotic Microangiopathy in Inverted Formin 2-Mediated Renal Disease2017
Rachel Challis
Dr Edwin Wong
Dr Holly Anderson
Dr Valerie Wilson
Dr Vicky Brocklebank
et al.
A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H–Related 3 Gene in Atypical Hemolytic Uremic Syndrome2016
Dr Vicky Brocklebank
Dr Edwin Wong
Professor Kevin Marchbank
Professor Tim Goodship
Professor David Kavanagh
et al.
The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies2016
Dr Isabel Pappworth
Dr Edwin Wong
Professor Neil Sheerin
Professor Kevin Marchbank
An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy2015
Dr Edwin Wong
Professor David Kavanagh
Anticomplement C5 therapy with eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome2015
Dr Edwin Wong
Dr Vicky Brocklebank
Professor Tim Goodship
Professor David Kavanagh
Dr Anna Richards
et al.
Characterisation of a C3 Mutation with Increased Resistance to Complement Regulation in an Individual with Recurrent C3GN in a Renel Transplant2015
Dr Edwin Wong
Dr Jeremy Palmer
Professor Neil Sheerin
Dr Isabel Pappworth
FH1-5(18-20) ameliorates experimental C3 glomerulopathy; generation and testing of a murine version for further pre-clinical experiments2015
Dr Edwin Wong
Rachel Challis
Professor Neil Sheerin
Dr Sally Johnson
Professor David Kavanagh
et al.
Patient stratification and therapy in atypical haemolytic uraemic syndrome (aHUS)2015
Dr Edwin Wong
Dr Isabel Pappworth
Professor Claire Harris
Professor Tim Goodship
Dr Sally Johnson
et al.
The national study of membranoproliferative glomerulonephrtis and C3 glomerulopathy - characterisation of the paediatric cohort2015
Dr Vicky Brocklebank
Dr Edwin Wong
Professor Tim Goodship
Professor David Kavanagh
Atypical haemolytic uraemic syndrome associated with a CD46 mutation triggered by Shigella flexneri2014
Dr Edwin Wong
Dr Holly Anderson
Rachel Challis
Dr Lisa Turnbull
Gladys -
et al.
Characterization of a Factor H Mutation That Perturbs the Alternative Pathway of Complement in a Family with Membranoproliferative GN2014
Dr Sally Johnson
Dr Edwin Wong
Making sense of the spectrum of glomerular disease associated with complement dysregulation2014
Dr Edwin Wong
Professor John Sayer
Sarcoidosis presenting with hypercalcaemia following withdrawal of long-term immunosuppression in renal transplantation2014
Dr Edwin Wong
Professor David Kavanagh
Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration2014
Rachel Challis
Dr Holly Anderson
Dr Edwin Wong
Dr Lisa Turnbull
Professor Kevin Marchbank
et al.
Atypical haemolytic uraemic syndrome associated with a novel hybrid CFH/CFHR3 gene2013
Dr Edwin Wong
Professor Tim Goodship
Professor David Kavanagh
Complement therapy in atypical haemolytic uraemic syndrome (aHUS)2013
Dr Edwin Wong
Mark Brady
Professor Neil Sheerin
Severe intestinal oedema due to nephrotic syndrome2013
Dr Edwin Wong
Dr Holly Anderson
Rachel Challis
Professor Kevin Marchbank
Professor David Kavanagh
et al.
Familial membranoproliferative glomerulonephritis type I associated with a functionally significant mutation in complement factor H2012
Dr Edwin Wong
Successful management of bilateral emphysematous pyelonephritis in end-stage polycystic kidneys: bilateral native nephrectomies and preservation of functioning renal transplant2011