Publications by Dr Ilse Pienaar - ePrints

Browsing publications by Dr Ilse Pienaar.

Newcastle Authors	Title	Year
Dr Joanna Elson Dr Ilse Pienaar	A Novel Mitochondria-Targeting Iron Chelator Neuroprotects Multimodally via HIF-1 Modulation Against a Mitochondrial Toxin in a Dopaminergic Cell Model of Parkinson’s Disease	2023
Dr Hilmar Sigurdsson Heather Hunter Dr Lisa Alcock Ross Wilson Dr Ilse Pienaar et al.	Safety and tolerability of adjunct non-invasive vagus nerve stimulation in people with parkinson's: a study protocol	2023
Dr Jannetta Steyn Dr Ilse Pienaar Dr Joanna Elson	Mitochondrial DNA population variation is not associated with Alzheimer's in the Japanese population: A consistent finding across global populations	2022
Dr Ilse Pienaar Dr Joanna Elson	Investigation of the Correlation Between Mildly Deleterious mtDNA Variations and the Clinical Progression of Multiple Sclerosis	2021
Dr Joanna Elson Dr Ilse Pienaar	Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants	2020
Dr Joanna Elson Dr Meera Soundararajan Dr Ilse Pienaar	Novel 1-hydroxypyridin-2-one metal chelators prevent and rescue ubiquitin proteasomal-related neuronal injury in an in vitro model of Parkinson’s disease	2020
Dr Cara Tomas Dr Ilse Pienaar Vicki Strassheim Professor Fai Ng Emerita Professor Julia Newton et al.	MtDNA population variation in Myalgic encephalomyelitis/Chronic fatigue syndrome in two populations: a study of mildly deleterious variants	2019
Rebecca Brennan Dr Ilse Pienaar Professor Francois van der Westhuizen Dr Joanna Elson	The unresolved role of mitochondrial DNA in Parkinson's disease: An overview of published studies, their limitations, and future prospects	2019
Dr Joanna Elson Dr Ilse Pienaar	Temporal-Spatial Profiling of Pedunculopontine Galanin-Cholinergic Neurons in the Lactacystin Rat Model of Parkinson’s Disease	2018
Dr Ilse Pienaar Dr Joanna Elson	Mildly deleterious mitochondrial DNA variants are less frequent in healthy older individuals, but not more prevalent in Alzheimer’s patients	2017
Alex Bury Dr Angela Pyle Dr Joanna Elson Professor Laura Greaves Dr Christopher Morris et al.	Mitochondrial DNA changes in pedunculopontine cholinergic neurons in Parkinson disease	2017
Dr Ilse Pienaar Dr Joanna Elson	MutPred mutational load analysis shows mildly deleterious mitochondrial DNA variants are not more prevalent in Alzheimer's patients, but may be under-represented in healthy older individuals	2017
Dr Ilse Pienaar Dr Joanna Elson Alex Bury	An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease	2015
Dr Ilse Pienaar Dr Joanna Elson Professor Raj Kalaria	Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease	2015
Dr Ilse Pienaar Dr Sasha Gartside Sabine Gretenkord Dr Joanna Elson	Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's disease	2015
Dr Ilse Pienaar Professor Patrick Chinnery	Existing and emerging mitochondrial-targeting therapies for altering Parkinson's disease severity and progression	2013
Dr Ilse Pienaar Dr Joanna Elson Dr Claudia Racca Dr Glyn Nelson Emeritus Professor Doug Turnbull et al.	Mitochondrial Abnormality Associates with Type-Specific Neuronal Loss and Cell Morphology Changes in the Pedunculopontine Nucleus in Parkinson Disease	2013
Dr Carole Proctor Dr Ilse Pienaar Dr Joanna Elson Emeritus Professor Thomas Kirkwood	Aggregation, impaired degradation and immunization targeting of amyloid-beta dimers in Alzheimer's disease: A stochastic modelling approach	2012
Dr Nichola Lax Dr Ilse Pienaar Dr Amy Reeve Philippa Hepplewhite Dr Evelyn Jaros et al.	Microangiopathy in the cerebellum of patients with mitochondrial DNA disease	2012