Publications by Dr Karen Wallace - ePrints

Browsing publications by Dr Karen Wallace.

Newcastle Authors	Title	Year
Dr Emma Fairhall Dr Michelle Charles Dr Phillip Probert Dr Karen Wallace Jen Gibb et al.	Pancreatic B-13 Cell Trans-Differentiation to Hepatocytes Is Dependent on Epigenetic-Regulated Changes in Gene Expression	2016
Dr Phillip Probert Dr Stephanie Meyer Fouzeyyah Alsaeedi Andrew Axon Dr Emma Fairhall et al.	An expandable donor-free supply of functional hepatocytes for toxicology	2015
Dr Emma Fairhall Dr Karen Wallace Professor Matthew Wright	Co-culture of B-13 hepatocyte progenitors with liver myofibroblasts promotes progenitor WNT signalling repression in response to glucocorticoids and enhances their transdifferentiation towards hepatocyte-like cells	2014
Dr Michelle Charles Dr Karen Wallace Dr Phillip Probert Professor Fiona Oakley Professor Matthew Wright et al.	THE glucocorticoid-dependent conversion of the B-13 progenitor cell into hepatocyte-like (B-13/H) cells is dependent on a short exposure to glucocorticoid and epigenetic alterations	2014
Dr Emma Fairhall Dr Karen Wallace Steven White Professor James Shaw Professor Alastair Burt et al.	Adult human exocrine pancreas differentiation to hepatocytes – potential source of a human hepatocyte progenitor for use in toxicology research	2013
Dr Emma Fairhall Claire Schwab Professor Christine Harrison FRCPath FMedSci Dr Karen Wallace Professor Matthew Wright et al.	The Hepatic Progenitor B-13 Cell Line Engrafts into the Mouse Liver and Transdifferentiates in Vivo	2013
Emma Fairhall Dr Karen Wallace	Myofibroblasts modulate the trans-differentiation of hepatic progenitor cells in vitro	2011
Dr Karen Wallace Professor James Shaw Professor Alastair Burt Professor Matthew Wright	Prolonged glucocorticoid exposure results in the appearance of hepatocytes in the adult pancreas	2011
Dr Karen Wallace QUAN LONG Dr Emma Fairhall Professor Matthew Wright	Serine/threonine protein kinase SGK1 in glucocorticoid-dependent transdifferentiation of pancreatic acinar cells to hepatocytes	2011
Dr Karen Wallace Emma Fairhall Professor Matthew Wright	Serum- and glucorticoid-induced kinase 1 (SGK1) plays a key role in the glucocorticoid dependent trans-differentiation of a pancreatic progenitor cell to hepatocytes	2011
Dr Karen Wallace Dr Emma Fairhall Professor Matthew Wright	AR42J-B-13 cell: An expandable progenitor to generate an unlimited supply of functional hepatocytes	2010
Dr Karen Wallace Professor Matthew Wright	Corrigendum to "Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury" [J Hepatol 49 (2008) 88-98] (DOI:10.1016/j.jhep.2008.01.032)	2010
Dr Karen Wallace Emeritus Professor Paul Flecknell Professor Alastair Burt Professor Matthew Wright	Disrupted Pancreatic Exocrine Differentiation and Malabsorption in Response to Chronic Elevated Systemic Glucocorticoid	2010
Dr Karen Wallace Dr Carlyn Marek Professor Matthew Wright	Glucocorticoid-dependent transdifferentiation of pancreatic progenitor cells into hepatocytes is dependent on transient suppression of WNT signalling	2010
Professor Matthew Wright Dr Karen Wallace Professor James Shaw Professor Alastair Burt Steven White et al.	Long term glucocorticoid therapy leads to pancreatic acinar trans-differentiation into hepatocyte-like cells	2010
Dr Karen Wallace Dr David Cowie Stephen Hill Andy Axon Steven White et al.	The PXR is a drug target for chronic inflammatory liver disease	2010
Dr Karen Wallace Professor James Shaw Professor Alastair Burt Professor Matthew Wright	Chronic Elevated Systemic Glucocorticocoid Results in Widespread Pancreatic-Hepatic Trans-Differentiation In Vivo	2009
Dr Karen Wallace Dr Carlyn Marek Professor Matthew Wright	Exocrine pancreas trans-differentiation to hepatocytes-A physiological response to elevated glucocorticoid in vivo	2009
Dr Roben Gieling Dr Karen Wallace	Interleukin-1 participates in the progression from liver injury to fibrosis	2009
Dr Carlyn Marek Dr Karen Wallace Professor Matthew Wright	Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics	2009
Dr Karen Wallace Dr Carlyn Marek Professor Matthew Wright	The Trans-Differentiation of Pancreatic Acinar Cells into Hepatocytes is Mediated by a Suppression of WNT Signalling Activity	2009
Dr Karen Wallace Professor Matthew Wright	Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury	2008
Dr Andrew Douglass Dr Karen Wallace Professor Matthew Wright	C1-3 recombinant antibody targeting myofibroblasts - Specific apoptosis reverses fibrosis in a sustained injury mouse model	2008
Dr Karen Wallace Professor Alastair Burt Professor Matthew Wright	Liver fibrosis	2008
Dr Martha Watson Dr Karen Wallace Dr Roben Gieling Professor Derek Manas Professor Derek Mann et al.	NF-κB is a critical regulator of the survival of rodent and human hepatic myofibroblasts	2008
Dr Karen Wallace Dr David Cowie Dr Carlyn Marek Professor Derek Mann Professor Matthew Wright et al.	PXR activation reduces hepatic TNF-alpha levels - A mechanism for inhibiting liver fibrosis	2008
Dr Karen Wallace Professor Muzlifah Haniffa Professor Matthew Collin Professor Matthew Wright	Skin Derived Fibroblasts Can Differentiate Into Hepatocyte-Like Cells	2008
Dr Karen Wallace Professor Matthew Wright	Targeting liver myofibroblasts: a novel approach in anti-fibrogenic therapy	2008
Dr Andrew Douglass Dr Karen Wallace Professor Matthew Wright	A human recombinant antibody for targeting anti-fibrogenic therapeutics to myofibroblasts in vivo	2007
Dr Carlyn Marek Dr Karen Wallace Professor Matthew Wright	Expression of CYP2S1 in human hepatic stellate cells	2007