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Lookup NU author(s): Professor Mushtaq Saleem, Professor Andrew Cant
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The clinical course of 10 children who have been diagnosed with major histocompatibility complex (MHC) class II deficiency (bare lymphocyte syndrome) in the UK over the past eight years is described. They have had a generally poor prognosis, with only two of the 10 still alive despite eight attempts at bone marrow transplantation in six patients. Overwhelming viral infection was the predominant cause of death. Alternative transplant strategies or novel therapies are required for these patients.
Author(s): Saleem MA, Arkwright PD, Davies EG, Cant AJ, Veys PA
Publication type: Article
Publication status: Published
Journal: Archives of Disease in Childhood
Year: 2000
Volume: 83
Issue: 4
Pages: 356-359
ISSN (print): 0003-9888
ISSN (electronic):
Publisher: BMJ Publishing Group Ltd
URL: http://dx.doi.org/10.1136/adc.83.4.356
DOI: 10.1136/adc.83.4.356
PubMed id: 10999878
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