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Lookup NU author(s): Professor Mark PearceORCiD, Emeritus Professor Jimmy Steele CBE, Dr David Campbell, Dr Julian Thomas
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Background. Helicobacter pylori, one of the commonest chronic bacterial infections of humankind, is an important risk factor for gastric carcinoma. It has also been suggested to be present in dental plaque. This study investigated the potential link between the number of teeth lost and H. pylori seropositivity at age 50 years. Methods. H. pylori seropositivity at age 50 years was investigated among 334 individuals born in Newcastle upon Tyne, United Kingdom, in May and June 1947 and related to the number of teeth lost, after adjusting for socioeconomic status. Results. The unadjusted risk of being seropositive for H. pylori increased with increasing number of teeth lost (odds ratio per tooth 1.03, 95% confidence interval 1.01-1.06, p = .019). However, after adjustment for socioeconomic status at birth and at age 50 years, the relationship was no longer significant (p = .36). Conclusions. Our results, obtained using prospectively collected data, suggest that any relationship between poor oral health and seropositivity to H. pylori may be due to both tooth loss and H. pylori colonization being associated with socioeconomic status and related factors.
Author(s): Pearce MS, Steele JG, Campbell DI, Thomas JE
Publication type: Article
Publication status: Published
Journal: Helicobacter
Year: 2005
Volume: 10
Issue: 1
Pages: 90-94
ISSN (print): 1083-4389
ISSN (electronic): 1523-5378
Publisher: Wiley-Blackwell Publishing Ltd.
URL: http://dx.doi.org/10.1111/j.1523-5378.2005.00296.x
DOI: 10.1111/j.1523-5378.2005.00296.x
PubMed id: 15691320
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