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From gene regulation to gene function: Regulatory networks in Bacillus subtilis

Lookup NU author(s): Professor Colin Harwood

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Abstract

Bacillus subtilis is a sporulating Gram-positive bacterium that lives primarily in the soil and associated water sources. The publication of the B. subtilis genome sequence and subsequent systematic functional analysis and gene regulation programmes, together with an extensive understanding of its biochemistry and physiology, makes this micro-organism a prime candidate in which to model regulatory networks in silico. In this paper we discuss combined molecular biological and bioinformatical approaches that are being developed to model this organism's responses to changes in its environment. Copyright © 2001 John Wiley & Sons, Ltd.

Publication metadata

Author(s): Harwood CR; Moszer I

Publication type: Article

Publication status: Published

Journal: Comparative and Functional Genomics

Year: 2002

Volume: 3

Issue: 1

Pages: 37-41

Print publication date: 01/01/2002

ISSN (print): 1531-6912

ISSN (electronic): 1532-6268

Publisher: Hindawi Publishing Corporation

URL: http://dx.doi.org/10.1002/cfg.138

DOI: 10.1002/cfg.138

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