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Lookup NU author(s): Dr Valerie Vidal, Marie-Christine Chaboissier, Professor Andreas Schedl
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Mutations in SOX9 are associated with male-to-female sex reversal in humans. To analyze Sox9 function during sex determination, we ectopically expressed this gene in XX gonads. Here, we show that Sox9 is sufficient to induce testis formation in mice, indicating that it can substitute for the sex-determining gene Sry.
Author(s): Vidal VPI, Chaboissier M-C, De Rooij DG, Schedl A
Publication type: Article
Publication status: Published
Journal: Nature Genetics
Year: 2001
Volume: 28
Issue: 3
Pages: 216-217
Print publication date: 01/01/2001
ISSN (print): 1061-4036
ISSN (electronic): 1469-7750
Publisher: Oxford University Press
URL: http://dx.doi.org/10.1038/90046
DOI: 10.1038/90046
PubMed id: 11431689
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