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Lookup NU author(s): Professor John LunecORCiD, Vanessa Ashton, Jennifer Wilson
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The prognostic value of the expression of the cyclin-dependent kinase inhibitor p21 and the p53 tumour suppressor gene was examined using immunohistochemistry in 60 patients with laryngeal cancer. Multivariate analysis using Cox's proportional hazard method, showed that p21 expression (P = 0.02) and advanced T stage (P = 0.003) significantly predicted survival. It was concluded that p21 expression may be a useful prognostic indicator in laryngeal cancer.
Author(s): Jeannon, J., Soames, J, Lunec, J, Awwad, S., Ashton, V., Wilson, J.
Publication type: Article
Publication status: Published
Journal: Clinical Otolaryngology and Allied Sciences
Year: 2000
Volume: 25
Issue: 1
Pages: 23-27
Print publication date: 01/01/2000
ISSN (print): 0307-7772
ISSN (electronic): 1749-4486
URL: http://dx.doi.org/10.1046/j.1365-2273.2000.00318.x
DOI: 10.1046/j.1365-2273.2000.00318.x
PubMed id: 10764233
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