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Lookup NU author(s): Professor Jonathan Rees
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I have tried to illustrate how the study of genetics can elucidate both the pattern of rashes within individuals and the pattern of disease and cutaneous phenotypes between individuals within and between communities. There is no one human genome - just human genomes. The pattern of allelic variation within and between populations is receiving increased attention because this store of human diversity can be seen to be both a result of and a weapon against disease. It cannot escape any dermatologist's attention that the manifest variation in skin appearance between people is one of the most polymorphic human traits. Understanding the significance of these differences, their relationship to disease and the reasons for these differences will provide insight not only into biology but also perhaps will illustrate the biological significance of physical appearance.
Author(s): Rees JL
Publication type: Review
Publication status: Published
Journal: Clinical and Experimental Dermatology
Year: 1999
Volume: 24
Issue: 5
Pages: 416-422
Print publication date: 01/09/1999
ISSN (print): 0307-6938
ISSN (electronic): 1365-2230
URL: http://dx.doi.org/10.1046/j.1365-2230.1999.00515.x
DOI: 10.1046/j.1365-2230.1999.00515.x
PubMed id: 10564335