Browse by author
Lookup NU author(s): Dr Lisa CroweORCiD, Dr Morven BrownORCiD, Jan Lecouturier, Professor Alastair GreystokeORCiD, Dr Desy Nuryunarsih, Ben RimmerORCiD, Professor Adam ToddORCiD, Professor Linda Sharp
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© The Author(s) 2025.Purpose: Develop an instrument to assess unmet needs in cancer patients using immuno-, biological and precision (IBP) therapies. Methods: Development followed COSMIN guidance. Instruments to assess unmet needs of advanced cancer patients were identified, and quality and content were evaluated in a systematic review (Phase 1). Semi-structured interviews with patients utilising IBP therapies (n = 31) and healthcare professionals (n = 22) explored supportive care needs (Phase 2). Phase 3 selected a base instrument to adapt, generated new items and iteratively refined these through six meetings involving professionals (n = 8) and public and patient involvement representatives (n = 9) and patient cognitive interviews (n = 16). Phase 4 piloted the new instrument (n = 50 patients). Results: Twenty-four instruments were identified; none was developed for patients utilising IBP therapies (Phase 1). Ten domains of unmet needs were identified from the interview data (Phase 2). SCNS-SF34 was selected as the base instrument. Informed by interview data, an “add-on module” (SCNS-TARGET) was developed for patients utilising IBP therapies comprising 25 questions (psychological domain, 7 items; information, 6; healthcare, 5; economic, 3; role, 2; physical, 1; social, 1; Phase 3). Levels of missingness were low; reliability varied across questions, and, on average, patients reported 7.40 (standard deviation = 8.43) unmet needs on SCNS-TARGET (Phase 4). Conclusions: SCNS-TARGET is designed for use alongside SCNS-SF34 to assess unmet needs in those using IBP therapies. Content and face validity have been established. Implications for Cancer Survivors: SCNS-TARGET can help researchers and healthcare professionals determine unmet needs and inform requirements for new services and interventions, among patients using IBP therapies.
Author(s): Crowe L, Brown MC, Lecouturier J, Greystoke A, Nuryunarsih D, Rimmer B, Bojke A, Bojke R, Richardson J, Wells M, Ezeala E, Carter L, Todd A, Sharp L
Publication type: Article
Publication status: Published
Journal: Journal of Cancer Survivorship
Year: 2025
Pages: epub ahead of print
Online publication date: 10/04/2025
Acceptance date: 18/03/2025
Date deposited: 22/04/2025
ISSN (print): 1932-2259
ISSN (electronic): 1932-2267
Publisher: Springer
URL: https://doi.org/10.1007/s11764-025-01787-4
DOI: 10.1007/s11764-025-01787-4
Data Access Statement: No datasets were generated or analysed during the current study.
Altmetrics provided by Altmetric
