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The Application of Radiomics in Vestibular Schwannomas

Lookup NU author(s): David Hamilton, Amar RajgorORCiD

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Abstract

© The Author(s), 2025.Objectives: Radiomics refers to converting medical images into high-quality quantitative data. This review examines applications of radiomics in vestibular schwannomas and future considerations for translation into clinical practice. Methods: The review was pre-registered on PROSPERO (ID: CRD42024579319). A comprehensive systematic review-informed search of OVID MEDLINE, EMBASE and Global Health online databases was undertaken. Keywords "acoustic neuroma"OR "vestibular schwannoma"OR "cerebellopontine angle tumour"OR "cerebellopontine tumour"OR "head and neck cancer"were combined with "radiomic"OR "signature"OR "machine learning"OR "artificial intelligence". Results: The studies (n=6) are categorised into two groups: Radiomics for Preoperative Decision-making (n=1) and Radiomics for Treatment Outcomes (n=5). Radiomic features are significantly associated with clinical outcomes. Radiomics-based predictive models are superior to expert vision. Conclusion: Radiomics has potential for improving multiple aspects of vestibular schwannoma care; however, lack of studies inhibits firm conclusions. Prospective studies are required to progress this field.


Publication metadata

Author(s): Gill T, Hamilton DW, Rajgor AD

Publication type: Review

Publication status: Published

Journal: Journal of Laryngology and Otology

Year: 2025

Pages: epub ahead of print

Online publication date: 27/03/2025

Acceptance date: 02/04/2018

ISSN (print): 0022-2151

ISSN (electronic): 1748-5460

Publisher: Cambridge University Press

URL: https://doi.org/10.1017/S0022215125000258

DOI: 10.1017/S0022215125000258


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