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Increasing Prevalence of Syphilis: Oral Manifestations, Diagnosis and Management

Lookup NU author(s): Dr Charlotte CurrieORCiD, Dr Anne Chambers, Dr Rachel GreenORCiD, Dr Max RobinsonORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

Introduction: Cases of syphilis are increasing, with 9513 cases diagnosed in England in 2023, the highest annual number since 1948. Oral surgery and oral and maxillofacial surgery teams should therefore be aware of how oral syphilis presents, the differential diagnosis and the appropriate care pathway and management. Case Series: We present 14 contemporary cases of oral syphilis to highlight the clinical features, outline the diagnostic pathway and document the management of the patients. We present the first patient in the literature to receive a diagnosis of neuro-syphilis following an initial presentation with an oral lesion, emphasising the importance of early diagnosis and treatment of this increasingly prevalent infection.

Publication metadata

Author(s): Currie CC, Chambers A, Endersby S, Green R, Price DA, Robinson N, Spoor E, Wilson A, Robinson M

Publication type: Article

Publication status: Published

Journal: Oral Surgery

Year: 2025

Pages: epub ahead of print

Online publication date: 20/02/2025

Acceptance date: 13/02/2025

Date deposited: 13/02/2025

ISSN (print): 1752-2471

ISSN (electronic): 1752-248X

Publisher: Wiley-Blackwell Publishing Ltd

URL: https://doi.org/10.1111/ors.12966

DOI: 10.1111/ors.12966

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