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Lookup NU author(s): Daniel Brooks, Dr Stephen Wright, Dr Nadia Mcallister, Dr Sara Graziadio, Dr John Davidson, Dr Mat Elameer, Dr Anthony RostronORCiD, Professor John SimpsonORCiD
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© 2024. Purpose: Chest radiographs in critically ill patients can be difficult to interpret due to technical and clinical factors. We sought to determine the agreement of chest radiographs and CT scans, and the inter-observer variation of chest radiograph interpretation, in intensive care units (ICUs). Methods: Chest radiographs and corresponding thoracic computerised tomography (CT) scans (as reference standard) were collected from 45 ICU patients. All radiographs were analysed by 20 doctors (radiology consultants, radiology trainees, ICU consultants, ICU trainees) from 4 different centres, blinded to CT results. Specificity/sensitivity were determined for pleural effusion, lobar collapse and consolidation/atelectasis. Separately, Fleiss' kappa for multiple raters was used to determine inter-observer variation for chest radiographs. Results: The median sensitivity and specificity of chest radiographs for detecting abnormalities seen on CTs scans were 43.2% and 85.9% respectively. Diagnostic sensitivity for pleural effusion was significantly higher among radiology consultants but no specialty/experience distinctions were observed for specificity. Median inter-observer kappa coefficient among assessors was 0.295 (“fair”). Conclusions: Chest radiographs commonly miss important radiological features in critically ill patients. Inter-observer agreement in chest radiograph interpretation is only “fair”. Consultant radiologists are least likely to miss thoracic radiological abnormalities. The consequences of misdiagnosis by chest radiographs remain to be determined.
Author(s): Brooks D, Wright SE, Beattie A, McAllister N, Anderson NH, Roy AI, Gonsalves P, Yates B, Graziadio S, Mackie A, Davidson J, Gopal SV, Whittle R, Zahed A, Barton L, Elameer M, Tuckett J, Holmes R, Sutcliffe A, Santamaria N, de Lalouviere LLH, Gupta S, Subramaniam J, Pearson JA, Brandwood M, Burnham R, Rostron AJ, Simpson AJ
Publication type: Article
Publication status: Published
Journal: Journal of Critical Care
Year: 2024
Volume: 82
Print publication date: 01/08/2024
Online publication date: 15/03/2024
Acceptance date: 02/04/2018
ISSN (print): 0883-9441
ISSN (electronic): 1557-8615
Publisher: Elsevier
URL: https://doi.org/10.1016/j.jcrc.2024.154760
DOI: 10.1016/j.jcrc.2024.154760
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