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A study protocol to investigate if Acipimox improves muscle function and sarcopenia –an open-label, uncontrolled, before-and-after experimental medicine feasibility study in community dwelling older adults.

Lookup NU author(s): Dr Claire McDonald, Matt Birkbeck, Dr Silvia Del DinORCiD, Dr Gráinne Gorman, Dr Kieren Hollingsworth, Clare Massarella, Dr Rana RehmanORCiD, Professor Lynn RochesterORCiD, Professor Avan SayerORCiD, Dr Huizhong Su, Dr Helen Tuppen, Dr Charlotte Warren, Professor Miles WithamORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

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Author(s): McDonald C, Alderson C, Birkbeck MG, Brown L, Del Din S, Gorman G, Hollingsworth KG, Massarella C, Rehman R, Rochester L, Sayer AA, Su H, Tuppen HAL, Warren C, Witham MD

Publication type: Article

Publication status: Published

Journal: BMJ Open

Year: 2024

Volume: 14

Online publication date: 27/02/2024

Acceptance date: 25/01/2024

Date deposited: 13/02/2024

ISSN (electronic): 2044-6055

Publisher: BMJ

URL: https://doi.org/10.1136/bmjopen-2023-076518

DOI: 10.1136/bmjopen-2023-076518

Data Access Statement: Access to the full dataset will be limited to the TMG and to authors of the trial publication. At the end of the trial, a deidentified dataset will be prepared and stored by Newcastle University. Requests for data sharing with study teams outside Newcastle University or the study Sponsor, including international requests, will be considered by a Data Access Committee with representation from the Funder, Sponsor and the trial Chief Investigator.

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