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Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer’s disease, restores synapse integrity and memory in a disease mouse model

Lookup NU author(s): Dr Faye McLeodORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Martin-Flores N, Podpolny M, McLeod F, Workman I, Crawford K, Ivanov D, Leonenko G, Escott-Price V, Salinas PC

Publication type: Article

Publication status: Published

Journal: Elife

Year: 2023

Volume: 12

Online publication date: 28/11/2023

Acceptance date: 25/09/2023

Date deposited: 13/03/2024

ISSN (electronic): 2050-084X

Publisher: eLife Sciences Publications, Ltd

URL: https://doi.org/10.7554/eLife.89453.1

DOI: 10.7554/eLife.89453.1

Data Access Statement: All data are available in the main text or the supplementary materials

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Funding

Funder referenceFunder name
Alzheimer’s Research UK (ARUK-PG2018A-002)
Alzheimer’s Society (AS-PG-17- 006)
MR/M024083/1
MR/S012125/1

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