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Co-option of a conserved host glutamine transporter facilitates aphid/Buchnera metabolic integration

Lookup NU author(s): Dr Catriona AndersonORCiD, Professor David Thwaites

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Publication metadata

Author(s): Duncan RP, Anderson CMH, Thwaites DT, Luetje CW, Wilson ACC

Publication type: Article

Publication status: Published

Journal: Proceedings of the National Academy of Sciences USA

Year: 2023

Volume: 120

Issue: 43

Online publication date: 16/10/2023

Acceptance date: 14/09/2023

Date deposited: 20/11/2023

ISSN (print): 0027-8424

ISSN (electronic): 1091-6490

Publisher: PNAS

URL: https://doi.org/10.1073/pnas.2308448120

DOI: 10.1073/pnas.2308448120

ePrints DOI: 10.57711/6eeq-sb08

Data Access Statement: Raw RNA-seq reads generated here were deposited in the NCBI Sequence Read Archive under BioProject PRJNA315109. Full length coding sequences of GLNT1 orthologs used for expression constructs were deposited in GenBank under accession numbers KY448282 (D. citri), KY448283 (P citri), KY448284 (P. humanus), and KY448285 (T. castaneum). Additional raw data (including FASTA files with insect GLNT1 sequences, alignments used for phylogenetic analysis, tree files, homology model files, original microscopy images, and electrophysiology trace files for figures 3, 4, and 6 can be accessed in the Zenodo repository (DOI: 10.5281/zenodo.8317238).


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Funding

Funder referenceFunder name
Newcastle University NUAcT fellowship
NSF award number DEB-1406631
NSF award number IOS-1354154
Rank Prize new lecturer grant
The Royal Society research grant RGS\R1\221113
The Physiological Society Momentum Fellowship number 47690-FR

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