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Lung transplantation: state of the art and current practice

Lookup NU author(s): Anders Andreasson, Professor John Dark

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Abstract

© 2023. Lung transplantation remains the standard of care for selected patients with progressive respiratory failure with advanced chronic lung disease. In the late 1980s, early surgical pioneers of lung transplantation developed programmes which included the surgical techniques and patient management principles that remain in use today. Since then, development of technology and advancements in clinical care to support patients on the lung transplant waiting list, along with advances in immunosuppression, have led to increased numbers of lung transplants and improved recipient outcomes. A total of 109 lung and heart–lung transplants were performed in the five UK lung transplant centres in 2021/22. However, there are currently 258 patients on the UK lung transplant waiting list, with 186 new registrations in 2021/22. In the modern era, research has focused on bridging this gap between the number of patients listed for lung transplantation and the number of available organs. Here, the focus is not only on increasing the number of potential organ donors, but on improving our ability to select, evaluate and improve the utilization of donor lungs.


Publication metadata

Author(s): Andreasson ASI, Dark JH

Publication type: Review

Publication status: Published

Journal: Surgery

Year: 2023

Volume: 41

Issue: 9

Pages: 580-586

Print publication date: 10/09/2023

Online publication date: 28/07/2023

Acceptance date: 02/04/2018

ISSN (print): 0263-9319

ISSN (electronic): 1878-1764

Publisher: Elsevier Ltd

URL: https://doi.org/10.1016/j.mpsur.2023.06.011

DOI: 10.1016/j.mpsur.2023.06.011


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