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α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity

Lookup NU author(s): Dr Daniel ErskineORCiD, Professor Johannes Attems, Professor Ian McKeith, Professor Tiago OuteiroORCiD

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).


Publication metadata

Author(s): Ghanem SS, Majbour NK, Vaikath NN, Ardah MT, Erskine D, Jensen NM, Fayyad M, Sudhakaran IP, Vasili E, Melachroinou K, Abdi IY, Poggiolini I, Santos P, Dorn A, Carloni P, Vekrellis K, Attems J, McKeith I, Outeiro TF, JEnsen PH, El-Agnaf OMA

Publication type: Article

Publication status: Published

Journal: Proceedings of the National Academy of Sciences

Year: 2022

Volume: 119

Issue: 15

Print publication date: 12/04/2022

Online publication date: 30/03/2022

Acceptance date: 15/02/2022

Date deposited: 05/07/2023

ISSN (print): 0027-8424

ISSN (electronic): 1091-64901

Publisher: Proceedings of the National Academy of Sciences

URL: https://doi.org/10.1073/pnas.2109617119

DOI: 10.1073/pnas.2109617119

PubMed id: 35353605


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Funding

Funder referenceFunder name
Alzheimer’s Research UK
Alzheimer’s Society
ARUK-RF2018C-005Alzheimer`s Research UK
G0400074
National Institute for Health Research Newcastle Biomedical Research Centre
Medical Research Council
Qatar Biomedical Research Institute
R223-2015-4222
R248-2016-2518
VR98

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