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Epigenomic translocation of H₃K₄me₃ broad domains over oncogenes following hijacking of super-enhancers

Lookup NU author(s): Dr Aneta Mikulasova, Dan Kent, Dr Marco Trevisan-HerrazORCiD, Nefeli Karataraki, Kent Fung, Dr Daniel Rico RodriguezORCiD, Dr Lisa Russell

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Author(s): Mikulasova A, Kent D, Trevisan-Herraz M, Karataraki N, Fung KTM, Ashby C, Cieslak A, Yaccoby S, van Rhee F, Zangari M, Thanendrarajan S, Schinke C, Morgan GJ, Asnafi V, Spicuglia S, Brackley CA, Corcoran AE, Hambleton S, Walker BA, Rico D, Russell LJ

Publication type: Article

Publication status: Published

Journal: Genome Research

Year: 2022

Volume: 32

Pages: 1343-1354

Print publication date: 01/07/2022

Online publication date: 21/12/2021

Acceptance date: 15/12/2021

Date deposited: 22/07/2022

ISSN (print): 1088-9051

ISSN (electronic): 1549-5469

Publisher: Cold Spring Harbor Laboratory Press

URL: https://doi.org/10.1101/gr.276042.121

DOI: 10.1101/gr.276042.121

Data Access Statement: The DNA sequencing data for the U266, KMS11, and MM1S myeloma cell lines generated in this study have been submitted to the NCBI BioProject database (https://www.ncbi.nlm.nih.gov/bioproject/) under accession number PRJNA635269. All raw and processed ChIP-seq data for the KMS11 and MM1S myeloma cell lines, as well as the PEER T-ALL cell line, have been submitted to the NCBI Gene Expression Omnibus (GEO; https://www.ncbi.nlm.nih.gov/geo/) under accession number GSE151556. All high-throughput sequencing data for the MM PDXs have been submitted to the European Genome-phenome Archive (https://ega-archive.org/) under accession number EGAS00001005684.

PubMed id: 34933939

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